Fabrice Senger
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senger.bsky.social
Fabrice Senger
@senger.bsky.social
Mechanobiology / Multi-cellular assemblies
Reposted by Fabrice Senger
📯👨‍🚀 Calling all #bioimage analysis aficionados. #EZInput is out! We wanted to bring #ImageJ’s capacity to record settings to the #Python ecosystem 🐍. It is a declarative library for generating UIs that just work. Done with @guijacquemet.bsky.social lab

arxiv.org/abs/2601.08859 #ScientificComputing
January 15, 2026 at 11:36 AM
The beasts
January 13, 2026 at 7:56 PM
Reposted by Fabrice Senger
Multiscale curvature modulates epithelial architecture and nuclear organization. https://www.biorxiv.org/content/10.64898/2026.01.12.698973v1
January 13, 2026 at 1:47 AM
Reposted by Fabrice Senger
New JCS snapshot - Bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organisation

Anne Müsch presents the key findings from their recent JCS paper with David Cohen and Francisco Lázaro-Diéguez.
journals.biologists.com/jcs/article/...
JCS snapshot - Bile canaliculi formation is dependent on ECM–cell-cell junctional crosstalk.
YouTube video by The Company of Biologists
youtu.be
January 12, 2026 at 4:17 PM
Reposted by Fabrice Senger
Available to read via #OpenAccess:
pubs.rsc.org/en/content/a...
Affordable, cleanroom-free millifluidic production of targeted lipid nanocarriers via additive manufacturing
Oscar Ces, James W. Hindley et al
@cesiboy.bsky.social @jwhindley.bsky.social
January 12, 2026 at 9:27 AM
will dig into WaveOrder as well
We are particular fans of DySTrack (www.biorxiv.org/content/10.6...) by @zimengwu33.bsky.social & Jonas Hartmann at UCL for live tracking of dynamic samples & WaveOrder (arxiv.org/abs/2412.097...) by @mattersoflight.bsky.social et al as a wave-optical framework for scalable biological microscopy 🐟🔬
📢Our latest #preprint list is now up on FocalPlane

In this list, we focus on new tools and techniques in imaging 🔬.

Let us know if you have any recommendations that we have missed.
focalplane.biologists.com/2026/01/09/m...
January 12, 2026 at 11:14 AM
With an ExM super res combo
Direct labeling of microtubule turnover reveals in-lattice repair and stabilization patterns in developing neurons https://www.biorxiv.org/content/10.64898/2026.01.11.698892v1
January 12, 2026 at 6:48 AM
Reposted by Fabrice Senger
I’m thrilled to share the first preprint from the Piacentino Lab @hopkinsmedicine.bsky.social! We show that developing inner ear requires a secreted lipid chaperone, APOD, working in a positive feedback loop to amplify FGF/MAPK signaling. 👂 #DevBio Check it out! www.biorxiv.org/content/10.6...
Lipid-mediated reinforcement of FGF/MAPK signaling enables robust otic placode specification
The formation of cranial placodes requires groups of ectodermal cells to interpret inductive signals in a robust and organized manner, yet how signaling responses are coordinated across a developing f...
www.biorxiv.org
January 8, 2026 at 10:56 PM
Reposted by Fabrice Senger
For 15(!) years I’ve been teaching introductory #MRI to grad students, and struggled to find a textbook for a wide variety of backgrounds. I'm happy to share an online textbook I created, fully open source (including code for generating figures and plots shown):
larsonlab.github.io/MRI-educatio...
Introduction to Principles of MRI — Principles of MRI
larsonlab.github.io
January 10, 2026 at 7:42 AM
Maybe Olivier Burris might be interested
Microscopy facility position coming up ⬇️
If you are looking for a position in a microscopy facility, we will also be recruiting very soon, be in touch as well :)
January 9, 2026 at 6:54 PM
on another note thinking about @deniswirtz.bsky.social recent reviews in NatMet, or @guijacquemet.bsky.social most recent paper in EMBO, it makes me think about this one : doi.org/10.1073/pnas...
January 7, 2026 at 4:01 PM
totally useless, but it looks good
January 7, 2026 at 3:35 PM
Reposted by Fabrice Senger
Won best thesis award with this video! 4 years of research and play in 3 minutes :')
youtu.be/so0fPlK1-LM
Smart microscopy, computer vision, and controlling cells with light -- my PhD thesis in 3 minutes
YouTube video by Pertz Lab
youtu.be
January 7, 2026 at 11:27 AM
Reposted by Fabrice Senger
A Perspective on 3D traction force microscopy provides practical experimental and computational guidance for users. @barrasa-fano.bsky.social

www.nature.com/articles/s41...
Guidance for 3D traction force microscopy today and in the next decade - Nature Methods
This Perspective envisions the future of 3DTFM and provides practical guidelines for experimental and computation strategies for its application.
www.nature.com
January 6, 2026 at 5:30 PM
Reposted by Fabrice Senger
Our paper describing the development of ShapeSpaceExplorer is now out: journals.plos.org/ploscompbiol... The software and documentation is available here: github.com/cmcb-warwick... Explainer thread below.
January 6, 2026 at 3:47 PM
very cool study and lots of resources available for others to use
January 6, 2026 at 1:32 PM
Reposted by Fabrice Senger
If you have time tomorrow, join my online talk about LLS/single molecule/microtubules and 3D data at @bioimagingna.bsky.social user group (18:00 CET for Europe).
I hope I manage to fit 25 movies into 20 cohesive slides and connection will be ok.
#HappyMicroscpyMonday #microscopycommunity - Join us tomorrow, Tue Jan 6 for a talk by Eugene Katrukha on "Single molecule imaging using LLS7", hosted by the BINA Lattice Lightsheet User Group

Learn more & register here: buff.ly/US5Xd2q
January 5, 2026 at 7:36 PM
Oh and i totally forget to mention the incredible Cristina, who powered the project with her incredible energy
Optogenetic SH3 nanoclustering of SRC and HCK uncovers the functional specificity of these redundant kinases in macrophages. https://www.biorxiv.org/content/10.64898/2025.12.27.692121v1
January 5, 2026 at 9:42 AM
Reposted by Fabrice Senger
Read the paper here: www.nature.com/articles/s41...

Thanks to @apek-shapeti.bsky.social , Alejandro Apolinar, Laurens Kimps, @bart-smeets.bsky.social , José Antonio Sanz Herrera and Hans Van Oosterwyck for helping me draft this exciting paper!!
Guidance for 3D traction force microscopy today and in the next decade - Nature Methods
This Perspective envisions the future of 3DTFM and provides practical guidelines for experimental and computation strategies for its application.
www.nature.com
January 5, 2026 at 9:32 AM
Soulful start of the year
January 1, 2026 at 8:16 PM
Start to prepare : youtu.be/P6q9xNvy5pM?...
Groundation - Dream
YouTube video by ReggaeXL
youtu.be
December 31, 2025 at 1:45 PM
Allways a good read, even for the lay
Our review article is now available in Annual Review of Condensed Matter Physics: “Full-Integer Topological Defects in Polar Active Matter.” @luizaangheluta.bsky.social @emmalaang.bsky.social doi.org/10.1146/annu...
December 29, 2025 at 11:11 AM
Reposted by Fabrice Senger
Optogenetic SH3 nanoclustering of SRC and HCK uncovers the functional specificity of these redundant kinases in macrophages. https://www.biorxiv.org/content/10.64898/2025.12.27.692121v1
December 28, 2025 at 5:30 AM
Reposted by Fabrice Senger
💻 Get direct access to 3D CAD models for Nikon microscope components!

✏️Our CAD request page puts detailed, ready-to-use files at your fingertips, so you can design with total precision and speed.

👉 Explore the page and grab your CAD files today: https://bit.ly/3Y4gzOV

#NikonMicroscopy
December 26, 2025 at 9:52 AM