Stig Ove Bøe
@stigoveboe.bsky.social
Epithelial Mechanics, Active Matter, Biology and Physics
Reposted by Stig Ove Bøe
Microfluidic pumping with active nematics! Self-organized and self-sustained. No external pumps.
@pnas.org @ub.edu
www.pnas.org/doi/10.1073/...
#ActiveMatter #Microfluidics #SoftMatter
@pnas.org @ub.edu
www.pnas.org/doi/10.1073/...
#ActiveMatter #Microfluidics #SoftMatter
Active nematic pumps | PNAS
Microfluidics involves the manipulation of flows at the microscale, typically requiring
external power sources to generate pressure gradients. Alte...
www.pnas.org
November 12, 2025 at 7:20 PM
Microfluidic pumping with active nematics! Self-organized and self-sustained. No external pumps.
@pnas.org @ub.edu
www.pnas.org/doi/10.1073/...
#ActiveMatter #Microfluidics #SoftMatter
@pnas.org @ub.edu
www.pnas.org/doi/10.1073/...
#ActiveMatter #Microfluidics #SoftMatter
Reposted by Stig Ove Bøe
New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tomgolde.bsky.social 🙌
@IBECBarcelona
www.biorxiv.org/content/10.1...
@IBECBarcelona
www.biorxiv.org/content/10.1...
September 1, 2025 at 3:31 PM
New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tomgolde.bsky.social 🙌
@IBECBarcelona
www.biorxiv.org/content/10.1...
@IBECBarcelona
www.biorxiv.org/content/10.1...
Reposted by Stig Ove Bøe
Collective cell motion has many forms, but rotation is the coolest of them all.
I'm @onenimesa.bsky.social , and in this short🧵, I'll highlight some instances of global tissue rotation like this one from @BauschLab
I'm @onenimesa.bsky.social , and in this short🧵, I'll highlight some instances of global tissue rotation like this one from @BauschLab
August 23, 2025 at 7:00 AM
Collective cell motion has many forms, but rotation is the coolest of them all.
I'm @onenimesa.bsky.social , and in this short🧵, I'll highlight some instances of global tissue rotation like this one from @BauschLab
I'm @onenimesa.bsky.social , and in this short🧵, I'll highlight some instances of global tissue rotation like this one from @BauschLab
Reposted by Stig Ove Bøe
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
March 19, 2025 at 5:31 PM
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
Reposted by Stig Ove Bøe
New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations.
The tissue morphogenesis logic, now engineered into living, programmable materials.
www.biorxiv.org/content/10.1...
#ActiveMatter #TissueEngineering
The tissue morphogenesis logic, now engineered into living, programmable materials.
www.biorxiv.org/content/10.1...
#ActiveMatter #TissueEngineering
June 30, 2025 at 7:53 AM
New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations.
The tissue morphogenesis logic, now engineered into living, programmable materials.
www.biorxiv.org/content/10.1...
#ActiveMatter #TissueEngineering
The tissue morphogenesis logic, now engineered into living, programmable materials.
www.biorxiv.org/content/10.1...
#ActiveMatter #TissueEngineering
Reposted by Stig Ove Bøe
FINALLY out in #Science Advances! 🎉
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!
It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀
www.science.org/doi/10.1126/...
#DevBio #CellBio #Microscopy
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!
It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀
www.science.org/doi/10.1126/...
#DevBio #CellBio #Microscopy
June 18, 2025 at 7:06 PM
FINALLY out in #Science Advances! 🎉
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!
It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀
www.science.org/doi/10.1126/...
#DevBio #CellBio #Microscopy
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!
It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀
www.science.org/doi/10.1126/...
#DevBio #CellBio #Microscopy
Reposted by Stig Ove Bøe
What do we see when looking at cells under the microscope? 👉Some are bigger than others, some are elongated and align with the neighbors & others seem to move. Cool, right? But wouldn't it be cooler to quantify these observations?
I'm @juliaeckert.bsky.social. Let's explore some analysis software!
I'm @juliaeckert.bsky.social. Let's explore some analysis software!
June 8, 2025 at 7:01 AM
What do we see when looking at cells under the microscope? 👉Some are bigger than others, some are elongated and align with the neighbors & others seem to move. Cool, right? But wouldn't it be cooler to quantify these observations?
I'm @juliaeckert.bsky.social. Let's explore some analysis software!
I'm @juliaeckert.bsky.social. Let's explore some analysis software!
Reposted by Stig Ove Bøe
Development of a transgenic zebrafish embryo. Credit to Dr. Mario Mendieta-Serrano. #ZebrafishZunday 🧪
June 1, 2025 at 8:04 AM
Development of a transgenic zebrafish embryo. Credit to Dr. Mario Mendieta-Serrano. #ZebrafishZunday 🧪
Reposted by Stig Ove Bøe
Reposted by Stig Ove Bøe
The tip of the cantilever consists of a fluorescent bead that contacts the epiblast. Because we know the force necessary to bend the cantilever, we can perform mechanical assays by driving the bead across the embryo and measure in real time the force applied to the tissue.
May 12, 2025 at 2:01 PM
The tip of the cantilever consists of a fluorescent bead that contacts the epiblast. Because we know the force necessary to bend the cantilever, we can perform mechanical assays by driving the bead across the embryo and measure in real time the force applied to the tissue.
Reposted by Stig Ove Bøe
🚨📣 New preprint alert!
Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos!
A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social
📄 www.biorxiv.org/content/10.1...
#devbio #mechanics
Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos!
A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social
📄 www.biorxiv.org/content/10.1...
#devbio #mechanics
Direct measurements of active forces and material properties unveil the active mechanics of early embryogenesis
Despite progress in probing tissue mechanics, direct long-term measurements in live embryonic epithelia are lacking. This limits our understanding of amniote embryonic morphogenesis, which takes place...
www.biorxiv.org
May 12, 2025 at 2:01 PM
🚨📣 New preprint alert!
Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos!
A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social
📄 www.biorxiv.org/content/10.1...
#devbio #mechanics
Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos!
A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social
📄 www.biorxiv.org/content/10.1...
#devbio #mechanics
Reposted by Stig Ove Bøe
Collective cell migration is fascinating!
Some tissues behave like fluids (motile), others like solids (jammed).
Check out some papers exploring this topic in this thread.
Some tissues behave like fluids (motile), others like solids (jammed).
Check out some papers exploring this topic in this thread.
May 11, 2025 at 1:02 PM
Collective cell migration is fascinating!
Some tissues behave like fluids (motile), others like solids (jammed).
Check out some papers exploring this topic in this thread.
Some tissues behave like fluids (motile), others like solids (jammed).
Check out some papers exploring this topic in this thread.
Reposted by Stig Ove Bøe
Trichoplax adhaerens is one of the simplest and most enigmatic animals on earth. Its body shows incredible fluidity, changing shape within minutes. In a recent visit by Andrea Pasini we had the chance to host and observe these amazing animals live.
[movie accelerated 3x; animal 0.5 to 1 mm in size]
[movie accelerated 3x; animal 0.5 to 1 mm in size]
May 10, 2025 at 5:53 PM
Trichoplax adhaerens is one of the simplest and most enigmatic animals on earth. Its body shows incredible fluidity, changing shape within minutes. In a recent visit by Andrea Pasini we had the chance to host and observe these amazing animals live.
[movie accelerated 3x; animal 0.5 to 1 mm in size]
[movie accelerated 3x; animal 0.5 to 1 mm in size]
Reposted by Stig Ove Bøe
B. Aigouy et al., Cell flow reorients the axis of planar polarity in the wing epithelium of Drosophila. Cell (2010). #EpithelialMechanics buff.ly/vH41dfH
May 8, 2025 at 11:02 AM
B. Aigouy et al., Cell flow reorients the axis of planar polarity in the wing epithelium of Drosophila. Cell (2010). #EpithelialMechanics buff.ly/vH41dfH
Reposted by Stig Ove Bøe
New in Nature Physics! In a great collaboration with @junlab.bsky.social and my students Henrik Weyer & @lwuerthner.bsky.social, we show how Min proteins in E. coli self-organize into robust, efficient patterns ensuring accurate cell division across conditions.
📄 www.nature.com/articles/s41...
📄 www.nature.com/articles/s41...
May 6, 2025 at 1:25 PM
New in Nature Physics! In a great collaboration with @junlab.bsky.social and my students Henrik Weyer & @lwuerthner.bsky.social, we show how Min proteins in E. coli self-organize into robust, efficient patterns ensuring accurate cell division across conditions.
📄 www.nature.com/articles/s41...
📄 www.nature.com/articles/s41...
Reposted by Stig Ove Bøe
It's #MicroscopyMonday, so let's take a peek into the 🔬
This movie was taken by Shinya Inuoe, who built the polarizing microscope that allowed scientists to see mitotic spindle fibers live for the first time.
Dr. Inuoe premiered his research at MBL.
This movie was taken by Shinya Inuoe, who built the polarizing microscope that allowed scientists to see mitotic spindle fibers live for the first time.
Dr. Inuoe premiered his research at MBL.
May 5, 2025 at 8:53 PM
It's #MicroscopyMonday, so let's take a peek into the 🔬
This movie was taken by Shinya Inuoe, who built the polarizing microscope that allowed scientists to see mitotic spindle fibers live for the first time.
Dr. Inuoe premiered his research at MBL.
This movie was taken by Shinya Inuoe, who built the polarizing microscope that allowed scientists to see mitotic spindle fibers live for the first time.
Dr. Inuoe premiered his research at MBL.
Reposted by Stig Ove Bøe
How can organs regenerate fast? Bioelectricity helps -- by coupling sub-second electrical injury signals to regenerative proliferation.
First preprint from my potsdoc :D with @liujinghui.bsky.social @ritamateus.bsky.social @mpi-cbg.de and collaborators @mpipks.bsky.social @csbdresden.bsky.social
First preprint from my potsdoc :D with @liujinghui.bsky.social @ritamateus.bsky.social @mpi-cbg.de and collaborators @mpipks.bsky.social @csbdresden.bsky.social
April 9, 2025 at 2:12 PM
How can organs regenerate fast? Bioelectricity helps -- by coupling sub-second electrical injury signals to regenerative proliferation.
First preprint from my potsdoc :D with @liujinghui.bsky.social @ritamateus.bsky.social @mpi-cbg.de and collaborators @mpipks.bsky.social @csbdresden.bsky.social
First preprint from my potsdoc :D with @liujinghui.bsky.social @ritamateus.bsky.social @mpi-cbg.de and collaborators @mpipks.bsky.social @csbdresden.bsky.social
Reposted by Stig Ove Bøe
Flocking and active solid behavior of epithelial cells in our new study in @pnas.org
Great work of Y. Shen, J. O'Byrne and
@andreasschoenit.bsky.social and collaboration with A. Maitra and R. Voituriez!
| PNAS www.pnas.org/doi/10.1073/...
Great work of Y. Shen, J. O'Byrne and
@andreasschoenit.bsky.social and collaboration with A. Maitra and R. Voituriez!
| PNAS www.pnas.org/doi/10.1073/...
April 19, 2025 at 2:11 PM
Flocking and active solid behavior of epithelial cells in our new study in @pnas.org
Great work of Y. Shen, J. O'Byrne and
@andreasschoenit.bsky.social and collaboration with A. Maitra and R. Voituriez!
| PNAS www.pnas.org/doi/10.1073/...
Great work of Y. Shen, J. O'Byrne and
@andreasschoenit.bsky.social and collaboration with A. Maitra and R. Voituriez!
| PNAS www.pnas.org/doi/10.1073/...
Reposted by Stig Ove Bøe
New paper on a field theory for coupling nematic ordering of the actin filaments with tissue elasticity.
arxiv.org/abs/2504.10689
arxiv.org/abs/2504.10689
Biomechanics of orientationally ordered epithelial tissue
Organogenesis involves large deformations and complex shape changes that require elaborate mechanical regulation. Models of tissue biomechanics have been introduced to account for the coupling between...
arxiv.org
April 18, 2025 at 7:58 AM
New paper on a field theory for coupling nematic ordering of the actin filaments with tissue elasticity.
arxiv.org/abs/2504.10689
arxiv.org/abs/2504.10689
Our new review on topological defects 🌀 in polar active matter is out on arXiv! Co-authored by Luiza Angheluta, Anna Lång, @emmalaang.bsky.social, and @stigoveboe.bsky.social. #ActiveMatter #TopologicalDefects #CollectiveBehavior
arxiv.org/abs/2504.03284
arxiv.org/abs/2504.03284
April 8, 2025 at 8:17 AM
Our new review on topological defects 🌀 in polar active matter is out on arXiv! Co-authored by Luiza Angheluta, Anna Lång, @emmalaang.bsky.social, and @stigoveboe.bsky.social. #ActiveMatter #TopologicalDefects #CollectiveBehavior
arxiv.org/abs/2504.03284
arxiv.org/abs/2504.03284
Reposted by Stig Ove Bøe
Congratulations to Zihui, Sano-san, and the team on this interesting work! They found that +1 topological defects attract neural progenitors—an observation that seems at odds with expectations for an extensile active nematic. www.nature.com/articles/s41...
Integer topological defects offer a methodology to quantify and classify active cell monolayers - Nature Communications
The orientation of elongated cells often rotates once around the center in tissue. Such structures are called +1 topological defects and play some roles in biological development. By inducing various ...
www.nature.com
March 13, 2025 at 4:33 AM
Congratulations to Zihui, Sano-san, and the team on this interesting work! They found that +1 topological defects attract neural progenitors—an observation that seems at odds with expectations for an extensile active nematic. www.nature.com/articles/s41...
Reposted by Stig Ove Bøe
Really excited to present the results of a great collaboration between our group @poldresden.bsky.social and Elliot Hawkes at @ucsantabarbara.bsky.social, which were just published in @science.org. A mix of physics, biology and robotics! 🤖 😀
▶️ www.science.org/doi/10.1126/...
▶️ www.science.org/doi/10.1126/...
Material-like robotic collectives with spatiotemporal control of strength and shape
The vision of robotic materials—cohesive collectives of robotic units that can arrange into virtually any form with any physical properties—has long intrigued both science and fiction. Yet, this visio...
www.science.org
February 24, 2025 at 6:44 PM
Really excited to present the results of a great collaboration between our group @poldresden.bsky.social and Elliot Hawkes at @ucsantabarbara.bsky.social, which were just published in @science.org. A mix of physics, biology and robotics! 🤖 😀
▶️ www.science.org/doi/10.1126/...
▶️ www.science.org/doi/10.1126/...
Reposted by Stig Ove Bøe
For #FluorescenceFriday, large lipid droplets (orange) and alpha-spectrin (blue) are shown in adipocytes 🔬 #Microscopy #CellBiology
February 7, 2025 at 4:20 PM
For #FluorescenceFriday, large lipid droplets (orange) and alpha-spectrin (blue) are shown in adipocytes 🔬 #Microscopy #CellBiology
Reposted by Stig Ove Bøe
New paper from the lab🎈. Introducing Micro Immune Response On-chip (MIRO), a device that replicates tumors and their microenvironment to better understand responses to immunotherapies (cyan=immune cells, red=cancer, green=CAFs).
www.nature.com/articles/s41...
@ibecbarcelona.eu
www.nature.com/articles/s41...
@ibecbarcelona.eu
February 7, 2025 at 11:46 AM
New paper from the lab🎈. Introducing Micro Immune Response On-chip (MIRO), a device that replicates tumors and their microenvironment to better understand responses to immunotherapies (cyan=immune cells, red=cancer, green=CAFs).
www.nature.com/articles/s41...
@ibecbarcelona.eu
www.nature.com/articles/s41...
@ibecbarcelona.eu
Reposted by Stig Ove Bøe
Thrilled to share our new preprint on detecting the nematic orientation field on surfaces of 3D multicellular systems!
www.biorxiv.org/content/10.1...
Huge thanks to all authors: @tobyandrews.bsky.social,Joe Pollard, @rashmi-priya.bsky.social, @yap-lab.bsky.social &Richard Morris
Any 3D systems?👇
www.biorxiv.org/content/10.1...
Huge thanks to all authors: @tobyandrews.bsky.social,Joe Pollard, @rashmi-priya.bsky.social, @yap-lab.bsky.social &Richard Morris
Any 3D systems?👇
January 29, 2025 at 11:01 PM
Thrilled to share our new preprint on detecting the nematic orientation field on surfaces of 3D multicellular systems!
www.biorxiv.org/content/10.1...
Huge thanks to all authors: @tobyandrews.bsky.social,Joe Pollard, @rashmi-priya.bsky.social, @yap-lab.bsky.social &Richard Morris
Any 3D systems?👇
www.biorxiv.org/content/10.1...
Huge thanks to all authors: @tobyandrews.bsky.social,Joe Pollard, @rashmi-priya.bsky.social, @yap-lab.bsky.social &Richard Morris
Any 3D systems?👇