PombeDoc
@pombedoc.bsky.social
Distinguished Professor, fission yeast geneticist. Replication stress and genome integrity. Photographer. 🏳️🌈
Reposted by PombeDoc
The latest #GENETICS study shows that the sisters separate (Ssep) gene in #Drosophila is essential for centromere cohesion during meiosis and is probably a new member of the cohesin complex. buff.ly/Qo75cpB
December 26, 2025 at 7:02 PM
The latest #GENETICS study shows that the sisters separate (Ssep) gene in #Drosophila is essential for centromere cohesion during meiosis and is probably a new member of the cohesin complex. buff.ly/Qo75cpB
Reposted by PombeDoc
Jose y Maria by Everett Patterson #ArtSky
www.everettpatterson.com?p=1835
Alt text: illustration of a Joseph and Mary, at a payphone trying to find shelter for the night in the rain. References to the birth of Jesus are dropped all over the illustration including a hotel sign that reads: "man ger"
www.everettpatterson.com?p=1835
Alt text: illustration of a Joseph and Mary, at a payphone trying to find shelter for the night in the rain. References to the birth of Jesus are dropped all over the illustration including a hotel sign that reads: "man ger"
December 23, 2025 at 9:14 PM
Jose y Maria by Everett Patterson #ArtSky
www.everettpatterson.com?p=1835
Alt text: illustration of a Joseph and Mary, at a payphone trying to find shelter for the night in the rain. References to the birth of Jesus are dropped all over the illustration including a hotel sign that reads: "man ger"
www.everettpatterson.com?p=1835
Alt text: illustration of a Joseph and Mary, at a payphone trying to find shelter for the night in the rain. References to the birth of Jesus are dropped all over the illustration including a hotel sign that reads: "man ger"
Reposted by PombeDoc
A Trump administration change to how the National Institutes of Health awards grants has sharply reduced early-stage investigators’ odds of securing funding, new data from the agency show. Teamed up with @aniloza.bsky.social for this @statnews.com story
www.statnews.com/2025/12/18/n...
www.statnews.com/2025/12/18/n...
NIH funding rates for early-career researchers plunged in 2025, new data show
A Trump administration change to how NIH awards grants has sharply reduced early-stage investigators’ odds of securing funding.
www.statnews.com
December 18, 2025 at 8:01 PM
A Trump administration change to how the National Institutes of Health awards grants has sharply reduced early-stage investigators’ odds of securing funding, new data from the agency show. Teamed up with @aniloza.bsky.social for this @statnews.com story
www.statnews.com/2025/12/18/n...
www.statnews.com/2025/12/18/n...
Reposted by PombeDoc
They want us to not want to be professors:
So our students don't question their propaganda.
So our research doesn't challenge their lies.
So our institutions can be replaced with so-called AI.
So our students don't question their propaganda.
So our research doesn't challenge their lies.
So our institutions can be replaced with so-called AI.
December 19, 2025 at 11:42 PM
They want us to not want to be professors:
So our students don't question their propaganda.
So our research doesn't challenge their lies.
So our institutions can be replaced with so-called AI.
So our students don't question their propaganda.
So our research doesn't challenge their lies.
So our institutions can be replaced with so-called AI.
Reposted by PombeDoc
The end goal is eugenicist. RFK and his ilk know that this will make vaccines more expensive and time-consuming — and therefore marginalized children are most likely to fall through the cracks.
This is about killing kids who aren't born to privilege.
www.washingtonpost.com/health/2025/...
This is about killing kids who aren't born to privilege.
www.washingtonpost.com/health/2025/...
U.S. plans to stop recommending most childhood vaccines, defer to doctors
The plan, which is not finalized, suggests children get fewer shots and shifts to a model telling parents to consult doctors to make their own vaccine choices.
www.washingtonpost.com
December 19, 2025 at 11:38 PM
The end goal is eugenicist. RFK and his ilk know that this will make vaccines more expensive and time-consuming — and therefore marginalized children are most likely to fall through the cracks.
This is about killing kids who aren't born to privilege.
www.washingtonpost.com/health/2025/...
This is about killing kids who aren't born to privilege.
www.washingtonpost.com/health/2025/...
December 16, 2025 at 5:44 PM
Reposted by PombeDoc
AMTRAK Pacific Surfliner (765) SAN->GTA [2025-12-11] Alert:
Route Obstruction: As of 7:45 AM PT Train 765 is stopped at San Juan Capistrano (SNC) due to municipal services investigating an incident involving a commuter train.
Route Obstruction: As of 7:45 AM PT Train 765 is stopped at San Juan Capistrano (SNC) due to municipal services investigating an incident involving a commuter train.
December 11, 2025 at 3:53 PM
AMTRAK Pacific Surfliner (765) SAN->GTA [2025-12-11] Alert:
Route Obstruction: As of 7:45 AM PT Train 765 is stopped at San Juan Capistrano (SNC) due to municipal services investigating an incident involving a commuter train.
Route Obstruction: As of 7:45 AM PT Train 765 is stopped at San Juan Capistrano (SNC) due to municipal services investigating an incident involving a commuter train.
Reposted by PombeDoc
AMTRAK Pacific Surfliner (562) LAX->SAN [2025-12-11] Alert:
Route Obstruction: As of 7:23 AM PT Train 562 is stopped at Irvine (IRV) due to municipal services investigating an incident involving a commuter train.
Route Obstruction: As of 7:23 AM PT Train 562 is stopped at Irvine (IRV) due to municipal services investigating an incident involving a commuter train.
December 11, 2025 at 3:33 PM
AMTRAK Pacific Surfliner (562) LAX->SAN [2025-12-11] Alert:
Route Obstruction: As of 7:23 AM PT Train 562 is stopped at Irvine (IRV) due to municipal services investigating an incident involving a commuter train.
Route Obstruction: As of 7:23 AM PT Train 562 is stopped at Irvine (IRV) due to municipal services investigating an incident involving a commuter train.
Reposted by PombeDoc
A bunch of us did a piece on RFK Jr.'s attacks on vaccines. Please circulate. Scientists and clinicians are sounding the alarm. It's time to act. youtube.com/shorts/4wnNy...
December 10, 2025 at 4:20 PM
A bunch of us did a piece on RFK Jr.'s attacks on vaccines. Please circulate. Scientists and clinicians are sounding the alarm. It's time to act. youtube.com/shorts/4wnNy...
Reposted by PombeDoc
Gift link to article www.nytimes.com/interactive/...
The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine (Gift Article)
A quiet policy change means the government is making fewer bets on long-term science.
www.nytimes.com
December 2, 2025 at 1:39 PM
Gift link to article www.nytimes.com/interactive/...
Reposted by PombeDoc
aw. Somewhere, I have pictures of Claude that I took maybe 15 years ago.
It's with heavy hearts that we share that Claude, our beloved albino alligator, has passed away at the age of 30. Claude brought joy to millions of people at the Academy and across the world during his 17 year tenure. We will miss him dearly. 🤍
December 2, 2025 at 10:27 PM
aw. Somewhere, I have pictures of Claude that I took maybe 15 years ago.
Reposted by PombeDoc
So apparently the administrators at Northwestern have caved to the extortionist demands of the Feds. Faculty voted 595-4 AGAINST this measure.
November 29, 2025 at 3:30 AM
So apparently the administrators at Northwestern have caved to the extortionist demands of the Feds. Faculty voted 595-4 AGAINST this measure.
Reposted by PombeDoc
I don’t think people outside of healthcare realize how much AAP is standing out as a moral backbone of medicine right now, especially in pediatrics. There is so much fear at institutions. Seeing an org directly and repeatedly targeted refuse to budge an inch is extraordinary.
AAP: ‘Stop wasting government resources to amplify false claims’ about vaccines, autism
The Centers for Disease Control and Prevention has updated its website to include false claims linking vaccines and autism, prompting a swift rebuke from the AAP and other medical experts.
publications.aap.org
November 27, 2025 at 6:17 AM
I don’t think people outside of healthcare realize how much AAP is standing out as a moral backbone of medicine right now, especially in pediatrics. There is so much fear at institutions. Seeing an org directly and repeatedly targeted refuse to budge an inch is extraordinary.
Reposted by PombeDoc
Gentle reminder that everyone should read Jacob and Monod, 1961. And then read it again every once in awhile. A master-class on clear writing (and, ya know, Nobel Prize winning stuff, too).
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Genetic regulatory mechanisms in the synthesis of proteins
The synthesis of enzymes in bacteria follows a double genetic control. The socalled structural genes determine the molecular organization of the prote…
www.sciencedirect.com
November 10, 2025 at 3:28 PM
Gentle reminder that everyone should read Jacob and Monod, 1961. And then read it again every once in awhile. A master-class on clear writing (and, ya know, Nobel Prize winning stuff, too).
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by PombeDoc
𝘐𝘯𝘤𝘦𝘯𝘥𝘪𝘢𝘮𝘰𝘦𝘣𝘢 𝘤𝘢𝘴𝘤𝘢𝘥𝘦𝘯𝘴𝘪𝘴 at 63°C 🔥 sure enough, wheels on fire... and faaast like the ayrton senna of amoebae
November 25, 2025 at 9:01 PM
𝘐𝘯𝘤𝘦𝘯𝘥𝘪𝘢𝘮𝘰𝘦𝘣𝘢 𝘤𝘢𝘴𝘤𝘢𝘥𝘦𝘯𝘴𝘪𝘴 at 63°C 🔥 sure enough, wheels on fire... and faaast like the ayrton senna of amoebae
Reposted by PombeDoc
The HPV vaccine is erasing cancer – here's the proof www.gavi.org/vaccineswork... via @gavi.org
The HPV vaccine is erasing cancer – here's the proof
More than a decade after the first HPV vaccination programmes rolled out, data from multiple countries reveals a dramatic fall in cervical cancers and precancers, confirming that HPV vaccines are high...
www.gavi.org
November 24, 2025 at 1:50 AM
The HPV vaccine is erasing cancer – here's the proof www.gavi.org/vaccineswork... via @gavi.org
Reposted by PombeDoc
If you use GMail, AI (Gemini) was turned on yesterday by default and now scans all of your content for machine learning. To turn off, go to Settings>General and scroll down. Uncheck the box for "Smart features."
There's other "Smart" add-ons as well, but that's the one that reads your content.
There's other "Smart" add-ons as well, but that's the one that reads your content.
November 20, 2025 at 5:32 PM
If you use GMail, AI (Gemini) was turned on yesterday by default and now scans all of your content for machine learning. To turn off, go to Settings>General and scroll down. Uncheck the box for "Smart features."
There's other "Smart" add-ons as well, but that's the one that reads your content.
There's other "Smart" add-ons as well, but that's the one that reads your content.
Reposted by PombeDoc
“We don’t deserve the trust of the nation if we’re unclear about the divisiveness of swastikas,” the official said, speaking on the condition of anonymity due to a fear of reprisal.
www.washingtonpost.com/national-sec...
www.washingtonpost.com/national-sec...
U.S. Coast Guard will no longer classify swastikas, nooses as hate symbols
The military service, which falls under the Department of Homeland Security, has drafted a new policy that classifies such items “potentially divisive.”
www.washingtonpost.com
November 20, 2025 at 8:09 PM
“We don’t deserve the trust of the nation if we’re unclear about the divisiveness of swastikas,” the official said, speaking on the condition of anonymity due to a fear of reprisal.
www.washingtonpost.com/national-sec...
www.washingtonpost.com/national-sec...
Reposted by PombeDoc
This is, of course excellent.
November 16, 2025 at 5:10 PM
This is, of course excellent.
Reposted by PombeDoc
1. Will Bunch’s recent column in the Philadelphia Inquirer has stayed with me, because it weaves various threads of history and politics into a clear and compelling tapestry with which ordinary people can act.
www.inquirer.com/opinion/trum...
www.inquirer.com/opinion/trum...
From autism to beards, the Trump regime wages war on ‘the different’ | Will Bunch
The Trump regime's disturbing views on everything from autism to transgender people have a scary "master race" vibe.
www.inquirer.com
October 30, 2025 at 2:15 PM
1. Will Bunch’s recent column in the Philadelphia Inquirer has stayed with me, because it weaves various threads of history and politics into a clear and compelling tapestry with which ordinary people can act.
www.inquirer.com/opinion/trum...
www.inquirer.com/opinion/trum...
Reposted by PombeDoc
Some nice thoughts here. Of course Meselson and Stahl (my personal favorite) make an appearance, as well as Nirenberg and Matthaei and many others. If you need inspiration today to keep plugging along (which I do!), this is for you.
www.asimov.press/p/beautiful-...
www.asimov.press/p/beautiful-...
What Makes an Experiment Beautiful?
A beautiful experiment is not just a reflection of human ingenuity but also efficient science.
www.asimov.press
November 13, 2025 at 8:46 PM
Some nice thoughts here. Of course Meselson and Stahl (my personal favorite) make an appearance, as well as Nirenberg and Matthaei and many others. If you need inspiration today to keep plugging along (which I do!), this is for you.
www.asimov.press/p/beautiful-...
www.asimov.press/p/beautiful-...
Reposted by PombeDoc
CAN LLMs write about science? @science.org decided to find out, and they did it the curious, scientific way. They did an experiment.
Love this thoughtful convo. www.lastwordonnothing.com/2025/11/12/w...
Love this thoughtful convo. www.lastwordonnothing.com/2025/11/12/w...
The Last Word On Nothing | Why AAAS won’t be using AI to write press releases anytime soon
www.lastwordonnothing.com
November 13, 2025 at 4:19 PM
CAN LLMs write about science? @science.org decided to find out, and they did it the curious, scientific way. They did an experiment.
Love this thoughtful convo. www.lastwordonnothing.com/2025/11/12/w...
Love this thoughtful convo. www.lastwordonnothing.com/2025/11/12/w...
Reposted by PombeDoc
Just a fundamental misunderstanding of how the scientific method works: It's not that someone *disagrees* was theory or finding and then argues with it, it's that you've got data that doesn't align and you go from there. Science isn't really about agreement or disagreement in an emotional sense.
JD Vance: "Science as practiced in its best form is that if you disagree with it, then you ought to criticize it and you ought to argue against it."
November 12, 2025 at 6:50 PM
Just a fundamental misunderstanding of how the scientific method works: It's not that someone *disagrees* was theory or finding and then argues with it, it's that you've got data that doesn't align and you go from there. Science isn't really about agreement or disagreement in an emotional sense.