Özge Özgüç
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oozguc.bsky.social
Özge Özgüç
@oozguc.bsky.social
320 followers 380 following 19 posts
Studying the tiny forces that shape life 🔬 || Postdoc with @xaviertrepat.bsky.social , @maitrejl.bsky.social lab alumna.
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Reposted by Özge Özgüç
biologists.bsky.social
Thank you to organisers Alex Dunn, @zevgartner.bsky.social, @adrianjacobo.bsky.social and Matthew Kutys and everyone who joined us for our Workshop on New Technologies for Studying and Reprogramming Development.
#BiologistsWorkshops
biologists.com/workshops
Group photo of Workshop attendees
November 20, 2025 at 7:56 AM
Reposted by Özge Özgüç
alleninstitute.org
A gourd-geous image of our lamin B1 cell line for your Halloween cell-ebrations! 🎃🧬

📸 Thanks to @oozguc.bsky.social for sharing this unbe-leaf-able shot!

#FluorescenceFriday
October 31, 2025 at 6:11 PM
oozguc.bsky.social
When #halloween meets #FluorescenceFriday 🎃
October 31, 2025 at 4:21 PM
Reposted by Özge Özgüç
xaviertrepat.bsky.social
📣Announcing the 4th edition of the EMBL‑IBEC Conference on “Engineering Multicellular Systems”, taking place 11–13 March 2026 in Barcelona. Exploring organoids, mechanobiology, embryo models, organ-on-chip systems, multiomics and more. Abstracts open now!
events.ibecbarcelona.eu/embl-ibec-co...
October 22, 2025 at 2:06 PM
Reposted by Özge Özgüç
cperez-gonzalez.bsky.social
1/ 🎉Excited to share our new preprint @vignjeviclab.bsky.social @davidbrueckner.bsky.social :

"Self-organization of tumor heterogeneity and plasticity"
biorxiv.org/content/10.1...

Tumor heterogeneity and plasticity drive metastasis and relapse. How is tumor patterning coordinated?

A thread👇
October 16, 2025 at 9:55 PM
Reposted by Özge Özgüç
tomgolde.bsky.social
Check out the preprint of my main work in the lab of @xaviertrepat.bsky.social @IBECBarcelona. Many thanks to all the people involved!
xaviertrepat.bsky.social Xavier Trepat @xaviertrepat.bsky.social · Sep 1
New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tomgolde.bsky.social‬ 🙌
@IBECBarcelona
www.biorxiv.org/content/10.1...
September 2, 2025 at 9:24 AM
Reposted by Özge Özgüç
redpenblackpen.bsky.social
Really just had something like this feeling this afternoon. It’s the high that keeps you coming back for more
Cartoon of a scientist peering through a microscope saying "Whoaah!!!". Title says "The best part of Science is knowing, for a moment, something that nobody else in the world knows."
August 8, 2025 at 1:27 AM
Reposted by Özge Özgüç
marija-matejcic.bsky.social
On cell extrusion in the #intestine!
After 80 years of observations, we finally took a deeper look thanks to 2D #organoids. We report:

3D #forces, #extrusion still only in the villus even without curvature, #lamellipodia generate 3D force.. and more. Have a look!
www.biorxiv.org/content/10.1...
July 4, 2025 at 10:21 AM
Reposted by Özge Özgüç
onenimesa.bsky.social
Have you ever thought about inflating tissues?
Or maybe quickly deflating those inflated tissues?

New #EpithelialMechanics pre-print: doi.org/10.1101/2025...
🧵 with pressure control, multiscale buckling, controlled wrinkling
July 3, 2025 at 2:23 PM
Reposted by Özge Özgüç
xaviertrepat.bsky.social
🚨 Second preprint of the week!

We uncover the multiscale dynamics of active viscoelastic buckling in epithelia.

We harness these mechanical instabilities for synthetic morphogenesis.

Led by @onenimesa.bsky.social 🙌. Theory by Marino Arroyo etal. @ibecbarcelona.eu

www.biorxiv.org/content/10.1...
July 3, 2025 at 10:25 AM
Reposted by Özge Özgüç
pauguillamat.bsky.social
New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations.

The tissue morphogenesis logic, now engineered into living, programmable materials.

www.biorxiv.org/content/10.1...

#ActiveMatter #TissueEngineering
June 30, 2025 at 7:53 AM
oozguc.bsky.social
highly recommended! 👇
bardinlab.bsky.social Bardin Lab @bardinlab.bsky.social · Jun 13
Students (Master's/PhD), do not miss this fantastic Developmental Biology course of @sorbonne-universite.fr and @institutcurie.bsky.social - It is FREE and open to international students, however, room and board + travel are not included.

training.institut-curie.org/courses/deve...
June 16, 2025 at 2:19 PM
Reposted by Özge Özgüç
the-node.bsky.social
Featured image with Özge Özgüç: the Node–FocalPlane image competition

Find out more about @oozguc.bsky.social and the story behind "Cell-estial bloom", which won the image competition we organised with @focalplane.bsky.social:
thenode.biologists.com/featured-ima...
A ‘Cell-estial Bloom’ of human induced pluripotent stem cells (hiPSCs) flourishes on a micropatterned island. This image presents a colony of live hiPSCs, with fluorescently labeled Lamin B delineating the nuclear lamina within each cell. Acquired with a Zeiss LSM 880 Airyscan microscope, this maximum intensity projection is enhanced with depth-coded coloring to reveal the captivating three-dimensional landscape.
May 7, 2025 at 8:22 AM
oozguc.bsky.social
From Turkiye’s Children’s Day to San Jordi in Catalonia, today is all about love, knowledge, and the future.
@ibecbarcelona.eu turned my microscopy image into a bookmark for the occasion🎈

23 Nisan kutlu olsun & Feliç Diada de Sant Jordi!
April 23, 2025 at 11:09 AM
Reposted by Özge Özgüç
epimechfc.bsky.social
How do hydraulic forces impact critical processes such as tissue integrity, cell fate decisions, and embryo development?

Hydraulics studies how fluids move and exert forces.

Join me in exploring few articles on hydraulics in #EpithelialMechanics
April 5, 2025 at 9:12 AM
Reposted by Özge Özgüç
kstapornwongkul.bsky.social
We’re looking for PhD students to join the lab! 🧫🧑‍🔬
Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/

‼️Deadline: April 15‼️
PhD Program
Empowering Curious Researchers at the Vienna BioCenter PhD Program Are you a curious and motivated student looking to launch a successful scientific career? Look no further than the Vienna BioCenter P...
training.vbc.ac.at
April 1, 2025 at 1:00 PM
Reposted by Özge Özgüç
jcellsci.bsky.social
In their Review, Laura Faure, Valeria Venturini @valeriaventurini.bsky.social and Pere Roca-Cusachs discuss the biological contexts of cell mechanical compression, the associated mechanisms and the experimental systems engineered to compress cells in vitro.
journals.biologists.com/jcs/article/...
Cartoon of techniques to apply one-dimensional, in-plane or volumetric cell compression in vitro.
March 28, 2025 at 11:46 AM
Reposted by Özge Özgüç
the-node.bsky.social
🎉Congratulations to the Top 3 images from the Node–FocalPlane image competition!

1️⃣"Cell-estial bloom" by @oozguc.bsky.social
2️⃣"Dancing actinotroch" by @allancarbal.bsky.social
3️⃣"Who’s active?" by @jupeloggia.bsky.social

thenode.biologists.com/results-from...

@focalplane.bsky.social #biologists100
"Cell-estial bloom" Image from Özge Özgüç: A ‘Cell-estial bloom’ of human induced pluripotent stem cells (hiPSCs) flourishes on a micropatterned island. This image presents a colony of live hiPSCs, with fluorescently labelled Lamin B delineating the nuclear lamina within each cell. Acquired with a Zeiss LSM 880 Airyscan microscope, this maximum intensity projection is enhanced with depth-coded coloring to reveal the captivating three-dimensional landscape. "Dancing actinotroch" by Allan Carrillo-Baltodano: Actinotroch larva of a phoronid worm with phalloidin shown in yellow and acetylated tubulin in magenta. Imaged with a Zeiss LSM 800 at 10 x magnification. "Who’s active?" by Julia Peloggia de Castro: The image depicts a zebrafish embryo at 9 hours post-fertilisation on a lateral view. Cells are stained with MitoTracker, which labels active mitochondria, and cell membranes are labelled in cyan with a EGFP transgenic membrane tag. Image was taken using a 20x objective on a spinning disk confocal microscope.
March 27, 2025 at 10:01 AM
Reposted by Özge Özgüç
focalplane.bsky.social
The Node-FocalPlane image competition at #biologists100.

All the votes are now in, and we can announce our three prize winners: @oozguc.bsky.social, @allancarbal.bsky.social and @jupeloggia.bsky.social.
Read more ⤵️: focalplane.biologists.com/2025/03/27/a...
Announcing the winners of the Node–FocalPlane image competition. - FocalPlane
Announcing the winners of the Node–FocalPlane image competition. - News
focalplane.biologists.com
March 27, 2025 at 10:08 AM
oozguc.bsky.social
Whaaat?! Cell-estial Bloom took 1st place in the Node–FocalPlane image competition! 🤯🤯🤯
the-node.bsky.social the Node @the-node.bsky.social · Mar 27
🎉Congratulations to the Top 3 images from the Node–FocalPlane image competition!

1️⃣"Cell-estial bloom" by @oozguc.bsky.social
2️⃣"Dancing actinotroch" by @allancarbal.bsky.social
3️⃣"Who’s active?" by @jupeloggia.bsky.social

thenode.biologists.com/results-from...

@focalplane.bsky.social #biologists100
"Cell-estial bloom" Image from Özge Özgüç: A ‘Cell-estial bloom’ of human induced pluripotent stem cells (hiPSCs) flourishes on a micropatterned island. This image presents a colony of live hiPSCs, with fluorescently labelled Lamin B delineating the nuclear lamina within each cell. Acquired with a Zeiss LSM 880 Airyscan microscope, this maximum intensity projection is enhanced with depth-coded coloring to reveal the captivating three-dimensional landscape. "Dancing actinotroch" by Allan Carrillo-Baltodano: Actinotroch larva of a phoronid worm with phalloidin shown in yellow and acetylated tubulin in magenta. Imaged with a Zeiss LSM 800 at 10 x magnification. "Who’s active?" by Julia Peloggia de Castro: The image depicts a zebrafish embryo at 9 hours post-fertilisation on a lateral view. Cells are stained with MitoTracker, which labels active mitochondria, and cell membranes are labelled in cyan with a EGFP transgenic membrane tag. Image was taken using a 20x objective on a spinning disk confocal microscope.
March 27, 2025 at 10:07 AM
oozguc.bsky.social
On my way to to the International Dutch Embryo Model Meeting 2025! 🚆
Excited to dive into the latest advances and have some great discussions.
If you’re around and curious about mechanics in development / mechanically accessible models, come find my poster!!
#IDEMM25
March 27, 2025 at 7:26 AM
oozguc.bsky.social
My image on display at #Biologists100! 🖼️🔬
So surreal to see “Cell-estial Bloom” showcased in this gallery among so many stunning images! Huge thanks to @LFort8 for the photo!

Also: ✨ it is the last day to vote! ✨
thenode.biologists.com/vote-for-you...
@the-node.bsky.social @focalplane.bsky.social
March 25, 2025 at 4:56 PM
Reposted by Özge Özgüç
kstapornwongkul.bsky.social
Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab!

Thankful for any retweet! 🫶

imba.onlyfy.jobs/job/l6u2m980
March 20, 2025 at 12:13 PM
Reposted by Özge Özgüç
the-node.bsky.social
Together with @focalplane.bsky.social, we're having an image competition to accompany the #Biologists100 conference.

Thank you everyone who submitted their images. Shortlisting only 15 was tough!

Browse through the gallery and vote for your favourite image:
thenode.biologists.com/vote-for-you...
Vote for your favourite image in the Node–FocalPlane image competition - the Node
Browse through the gallery of the 15 shortlisted images and vote for your favourite image by Wednesday 26 March.
thenode.biologists.com
March 11, 2025 at 1:39 PM
oozguc.bsky.social
My image is shortlisted and will be displayed at #100Biologists! 🎉

This “Cell-estial Bloom” features LaminB-labeled cells from @alleninstitute.bsky.social glowing in all their fluorescent glory! ✨

All very incredible images—check them out and vote for your favorite (Hope it’s mine! 🤞)!
a colony of live hiPSCs, with fluorescently labeled Lamin B delineating the nuclear lamina within each cell. this maximum intensity projection is enhanced with depth-coded coloring to reveal the captivating three-dimensional landscape.
March 12, 2025 at 2:21 PM