Tom Golde
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tomgolde.bsky.social
Tom Golde
@tomgolde.bsky.social
biophysics. post-doc @XavierTrepat lab barcelona. currently focused on intermediate filaments and epithelial tissues.
Reposted by Tom Golde
I am putting together a collection of video-protocols we (will) use in tissue mechanics research🌀
I hope to help consolidate established methods, but also showcase a few up-and-coming ones in our blooming field.
Abstract submission by March 2026! Get in touch✨
#JoVETissueMech
#ReproducibleTissueMech
December 16, 2025 at 2:28 PM
Today I'm traveling to Portimao, Portugal to play with the German Men's Masters National team at the World Beach Ultimate Championships 2025. Wish me luck.
wbuc.sport
November 15, 2025 at 8:51 AM
Check out the preprint of my main work in the lab of @xaviertrepat.bsky.social @IBECBarcelona. Many thanks to all the people involved!
New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tomgolde.bsky.social‬ 🙌
@IBECBarcelona
www.biorxiv.org/content/10.1...
September 2, 2025 at 9:24 AM
I'm proud to contributing to the development of the experimental system of this amazing study.

I heard @onenimesa.bsky.social will do a whole thread soon.

And maybe we have even more in the pipeline...
🚨 Second preprint of the week!

We uncover the multiscale dynamics of active viscoelastic buckling in epithelia.

We harness these mechanical instabilities for synthetic morphogenesis.

Led by @onenimesa.bsky.social 🙌. Theory by Marino Arroyo etal. @ibecbarcelona.eu

www.biorxiv.org/content/10.1...
July 3, 2025 at 11:04 AM
Reposted by Tom Golde
New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations.

The tissue morphogenesis logic, now engineered into living, programmable materials.

www.biorxiv.org/content/10.1...

#ActiveMatter #TissueEngineering
June 30, 2025 at 7:53 AM
Reposted by Tom Golde
What do we see when looking at cells under the microscope? 👉Some are bigger than others, some are elongated and align with the neighbors & others seem to move. Cool, right? But wouldn't it be cooler to quantify these observations?

I'm @juliaeckert.bsky.social. Let's explore some analysis software!‬
June 8, 2025 at 7:01 AM
New paper from the lab🎈. Introducing Micro Immune Response On-chip (MIRO), a device that replicates tumors and their microenvironment to better understand responses to immunotherapies (cyan=immune cells, red=cancer, green=CAFs).
www.nature.com/articles/s41...
@ibecbarcelona.eu
February 7, 2025 at 2:11 PM
🎄 𝗜𝘁’𝘀 𝗕𝗲𝗴𝗶𝗻𝗻𝗶𝗻𝗴 𝘁𝗼 𝗟𝗼𝗼𝗸 𝗮 𝗟𝗼𝘁 𝗟𝗶𝗸𝗲 𝗖𝗵𝗿𝗶𝘀𝘁𝗺𝗮𝘀... 𝗨𝗻𝗱𝗲𝗿 𝘁𝗵𝗲 𝗠𝗶𝗰𝗿𝗼𝘀𝗰𝗼𝗽𝗲! 🔬

Why buy Christmas trees when you can "grow" one using micropatterning and @alleninstitute.bsky.social cells that come with their own LaminB1 "ornaments"?

Happy #FluorescenceFriday! ✨❄️
December 13, 2024 at 9:56 AM
Great stuff from our lab!
🎈New preprint! We study how single cells move up, down and about fibronectin gradients. Experiments by @icfortunato.bsky.social, theory by David Bruckner. Collaboration with @raimonsunyer.bsky.social and @ehannezo.bsky.social 👇https://biorxiv.org/cgi/content/short/2024.12.02.626413v1
December 4, 2024 at 11:29 AM
Hello world! I wrote something about intermediate filaments and epithelial mechanics back on twitter. But you can also find it here :)
But what about intermediate filaments? This question is often in my head when I see a talk about cell mechanics focused on actin or microtubules. I am @tom_golde and today I will give you a short overview about the role of intermediate filaments (IF) in #EpithelialMechanics
November 18, 2024 at 10:19 AM