Tom Golde
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tomgolde.bsky.social
Tom Golde
@tomgolde.bsky.social
biophysics. post-doc @XavierTrepat lab barcelona. currently focused on intermediate filaments and epithelial tissues.
Today I'm traveling to Portimao, Portugal to play with the German Men's Masters National team at the World Beach Ultimate Championships 2025. Wish me luck.
wbuc.sport
November 15, 2025 at 8:51 AM
Check out the preprint of my main work in the lab of @xaviertrepat.bsky.social @IBECBarcelona. Many thanks to all the people involved!
New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tomgolde.bsky.social‬ 🙌
@IBECBarcelona
www.biorxiv.org/content/10.1...
September 2, 2025 at 9:24 AM
I'm proud to contributing to the development of the experimental system of this amazing study.

I heard @onenimesa.bsky.social will do a whole thread soon.

And maybe we have even more in the pipeline...
🚨 Second preprint of the week!

We uncover the multiscale dynamics of active viscoelastic buckling in epithelia.

We harness these mechanical instabilities for synthetic morphogenesis.

Led by @onenimesa.bsky.social 🙌. Theory by Marino Arroyo etal. @ibecbarcelona.eu

www.biorxiv.org/content/10.1...
July 3, 2025 at 11:04 AM
Reposted by Tom Golde
New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations.

The tissue morphogenesis logic, now engineered into living, programmable materials.

www.biorxiv.org/content/10.1...

#ActiveMatter #TissueEngineering
June 30, 2025 at 7:53 AM
Reposted by Tom Golde
What do we see when looking at cells under the microscope? 👉Some are bigger than others, some are elongated and align with the neighbors & others seem to move. Cool, right? But wouldn't it be cooler to quantify these observations?

I'm @juliaeckert.bsky.social. Let's explore some analysis software!‬
June 8, 2025 at 7:01 AM
New paper from the lab🎈. Introducing Micro Immune Response On-chip (MIRO), a device that replicates tumors and their microenvironment to better understand responses to immunotherapies (cyan=immune cells, red=cancer, green=CAFs).
www.nature.com/articles/s41...
@ibecbarcelona.eu
February 7, 2025 at 2:11 PM
🎄 𝗜𝘁’𝘀 𝗕𝗲𝗴𝗶𝗻𝗻𝗶𝗻𝗴 𝘁𝗼 𝗟𝗼𝗼𝗸 𝗮 𝗟𝗼𝘁 𝗟𝗶𝗸𝗲 𝗖𝗵𝗿𝗶𝘀𝘁𝗺𝗮𝘀... 𝗨𝗻𝗱𝗲𝗿 𝘁𝗵𝗲 𝗠𝗶𝗰𝗿𝗼𝘀𝗰𝗼𝗽𝗲! 🔬

Why buy Christmas trees when you can "grow" one using micropatterning and @alleninstitute.bsky.social cells that come with their own LaminB1 "ornaments"?

Happy #FluorescenceFriday! ✨❄️
December 13, 2024 at 9:56 AM
Great stuff from our lab!
🎈New preprint! We study how single cells move up, down and about fibronectin gradients. Experiments by @icfortunato.bsky.social, theory by David Bruckner. Collaboration with @raimonsunyer.bsky.social and @ehannezo.bsky.social 👇https://biorxiv.org/cgi/content/short/2024.12.02.626413v1
December 4, 2024 at 11:29 AM
Hello world! I wrote something about intermediate filaments and epithelial mechanics back on twitter. But you can also find it here :)
But what about intermediate filaments? This question is often in my head when I see a talk about cell mechanics focused on actin or microtubules. I am @tom_golde and today I will give you a short overview about the role of intermediate filaments (IF) in #EpithelialMechanics
November 18, 2024 at 10:19 AM