Microbe-host enthusiast tackling TB and beyond | Passionate #SciComm advocate | #MicroSky #TBSky #CNRS | He/Him | Views mine
Weโre thrilled to share our new study revealing how the chromatin regulator SP140 preserves protective T cell immunity during #tuberculosis infection by restraining harmful type I IFN responses.
๐ ๐ฅ๐ฒ๐ฎ๐ฑ ๐๐ต๐ฒ ๐ฝ๐ฟ๐ฒ๐ฝ๐ฟ๐ถ๐ป๐: shorturl.at/r5jd9
Watching Max Caouaille and Aizat Abdul at #TBVAC was genuinely moving. Great science, great storytelling, huge passion.
The future of research is in very good hands. ๐
Watching Max Caouaille and Aizat Abdul at #TBVAC was genuinely moving. Great science, great storytelling, huge passion.
The future of research is in very good hands. ๐
The 2026 UK CellularMicrobiologyNetwork meeting will be held 22nd - 23rd of June at @wwiem-qub.bsky.social in Belfast.
Researchers from the UK and beyond are invited to share exciting work on the mechanisms of host-pathogen interactions.
Follow us to stay tuned! www.ukcellmicro.org
๐ Huge thanks to the team, and our collaborators! Supported by @agencerecherche.bsky.social, @frm-officiel.bsky.social, and Bettencourt Schueller Foundation.
๐ Huge thanks to the team, and our collaborators! Supported by @agencerecherche.bsky.social, @frm-officiel.bsky.social, and Bettencourt Schueller Foundation.
๐น NCAM1 is the main polysialic acid carrier in inflammatory monocytes, and its loss phenocopies ST8SIA4 deficiency.
๐น Polysialylation regulates CCR2 surface distribution, cytoskeleton, and chemokine binding, revealing a new mechanism controlling immune cell trafficking.
๐น NCAM1 is the main polysialic acid carrier in inflammatory monocytes, and its loss phenocopies ST8SIA4 deficiency.
๐น Polysialylation regulates CCR2 surface distribution, cytoskeleton, and chemokine binding, revealing a new mechanism controlling immune cell trafficking.
๐น Human ๐๐8๐๐ผ๐ด4 variants are associated with lower monocyte and lymphocyte counts and higher SLE risk.
๐น ST8SIA4 deficiency causes monocytopenia in mice by impairing CCR2-dependent monocyte exit from bone marrow.
...
๐น Human ๐๐8๐๐ผ๐ด4 variants are associated with lower monocyte and lymphocyte counts and higher SLE risk.
๐น ST8SIA4 deficiency causes monocytopenia in mice by impairing CCR2-dependent monocyte exit from bone marrow.
...
โ๏ธ Aurรฉlien Boyancรฉ, Nelly Gilles, @yoannrombouts.bsky.social & coll. @ipbstoulouse.bsky.social
๐ shorturl.at/IDwza
๐ A short thread...
โ๏ธ Aurรฉlien Boyancรฉ, Nelly Gilles, @yoannrombouts.bsky.social & coll. @ipbstoulouse.bsky.social
๐ shorturl.at/IDwza
๐ A short thread...
Hereโs to a bright, productive 2026! ๐คฉ
@mcaouaille.bsky.social @saurabhchugh09.bsky.social @vogeleerp.bsky.social @yoannrombouts.bsky.social & more!
Hereโs to a bright, productive 2026! ๐คฉ
@mcaouaille.bsky.social @saurabhchugh09.bsky.social @vogeleerp.bsky.social @yoannrombouts.bsky.social & more!
1. We've launched a new website for our lab: www.brysonlab.org
2. With some new funding, we are recruiting for new postdocs and graduate students. The projects build upon our previous studies of antigen presentation and phagosome biology and go into new exciting dimensions!
1. We've launched a new website for our lab: www.brysonlab.org
2. With some new funding, we are recruiting for new postdocs and graduate students. The projects build upon our previous studies of antigen presentation and phagosome biology and go into new exciting dimensions!
More info: shorturl.at/U6zSa
#MicroSky #Salmonella
More info: shorturl.at/U6zSa
#MicroSky #Salmonella
What a wonderful day with incredibly friendly hosts and such brilliant, motivated students!
๐ซ๐ท๐ฎ๐ณ Long live Franco-Indian cooperation!
What a wonderful day with incredibly friendly hosts and such brilliant, motivated students!
๐ซ๐ท๐ฎ๐ณ Long live Franco-Indian cooperation!
#Tuberculosis #ImmunoSky #MicroSky #Microscopy
#Tuberculosis #ImmunoSky #MicroSky #Microscopy
โข Without SP140, excess IFN-I traps CD8โบ and CD4โบ T cells and prevents their movement in lesions.
โข The few T cells that enter become almost immobile.
โข Blocking IFNAR fully restores T cell motility and surveillance.
โข Without SP140, excess IFN-I traps CD8โบ and CD4โบ T cells and prevents their movement in lesions.
โข The few T cells that enter become almost immobile.
โข Blocking IFNAR fully restores T cell motility and surveillance.
Weโre thrilled to share our new study revealing how the chromatin regulator SP140 preserves protective T cell immunity during #tuberculosis infection by restraining harmful type I IFN responses.
๐ ๐ฅ๐ฒ๐ฎ๐ฑ ๐๐ต๐ฒ ๐ฝ๐ฟ๐ฒ๐ฝ๐ฟ๐ถ๐ป๐: shorturl.at/r5jd9
Weโre thrilled to share our new study revealing how the chromatin regulator SP140 preserves protective T cell immunity during #tuberculosis infection by restraining harmful type I IFN responses.
๐ ๐ฅ๐ฒ๐ฎ๐ฑ ๐๐ต๐ฒ ๐ฝ๐ฟ๐ฒ๐ฝ๐ฟ๐ถ๐ป๐: shorturl.at/r5jd9
These anucleate fat cells still metabolize lipids and glucose, support blood cell production, and may shape the bone marrow niche and hematopoiesis.๐ฉธ
๐ shorturl.at/bunUV
#Hematopoiesis #Adipocytes #BoneMarrow
These anucleate fat cells still metabolize lipids and glucose, support blood cell production, and may shape the bone marrow niche and hematopoiesis.๐ฉธ
๐ shorturl.at/bunUV
#Hematopoiesis #Adipocytes #BoneMarrow
#Tuberculosis
#Tuberculosis
๐ฌ @institutfresnel.bsky.social ๐ค @univ-amu.fr @centralemed.bsky.social @cnrs.fr
๐ @cnrs-dr12.bsky.social
๐ฌ @institutfresnel.bsky.social ๐ค @univ-amu.fr @centralemed.bsky.social @cnrs.fr
๐ @cnrs-dr12.bsky.social
Our preprint is out, curious to hear your take! ๐
www.biorxiv.org/content/10.1...
Our preprint is out, curious to hear your take! ๐
www.biorxiv.org/content/10.1...