Olivier Neyrolles
@oneyrolles.bsky.social
Director of https://www.ipbs.fr Toulouse 🇫🇷🇪🇺
Microbe-host enthusiast tackling TB and beyond | Passionate #SciComm advocate | #MicroSky #TBSky #CNRS | He/Him | Views mine
Microbe-host enthusiast tackling TB and beyond | Passionate #SciComm advocate | #MicroSky #TBSky #CNRS | He/Him | Views mine
Pinned
Olivier Neyrolles
@oneyrolles.bsky.social
· Sep 23
Inorganic sulfate is critical for Mycobacterium tuberculosis lung tissue colonization and redox balance | PNAS
Tuberculosis remains the deadliest infectious disease caused by a single pathogen,
highlighting the urgent need for novel therapies. A deeper under...
www.pnas.org
Excited to share Wendy Le Mouëllic’s PhD work, now published in @pnas.org!
It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance.
Huge congrats to Wendy & colleagues!
shorturl.at/WbFQC
It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance.
Huge congrats to Wendy & colleagues!
shorturl.at/WbFQC
Reposted by Olivier Neyrolles
Two M. tuberculosis RelE toxins don’t cut mRNA, they slice 16S rRNA itself, shutting down translation in a totally unexpected way, new study reveals.
A big leap in understanding TB’s survival tricks and new angles for therapies.
📖 shorturl.at/Z8MVX
✍️ @genevauxpierre.bsky.social & coll.
#MicroSky
A big leap in understanding TB’s survival tricks and new angles for therapies.
📖 shorturl.at/Z8MVX
✍️ @genevauxpierre.bsky.social & coll.
#MicroSky
November 18, 2025 at 8:56 AM
Two M. tuberculosis RelE toxins don’t cut mRNA, they slice 16S rRNA itself, shutting down translation in a totally unexpected way, new study reveals.
A big leap in understanding TB’s survival tricks and new angles for therapies.
📖 shorturl.at/Z8MVX
✍️ @genevauxpierre.bsky.social & coll.
#MicroSky
A big leap in understanding TB’s survival tricks and new angles for therapies.
📖 shorturl.at/Z8MVX
✍️ @genevauxpierre.bsky.social & coll.
#MicroSky
👏👏👏
So proud of our co-PI!
This well-deserved recognition honors Luciana’s outstanding scientific contributions, her dedication to mentoring, and her support for young women in research. Please join me in congratulating her on this incredible achievement!
So proud of our co-PI!
This well-deserved recognition honors Luciana’s outstanding scientific contributions, her dedication to mentoring, and her support for young women in research. Please join me in congratulating her on this incredible achievement!
We are thrilled to congratulate @lucianabalboa.bsky.social, co-leader of our IPBS/CNRS-CONICET lab, for receiving a special mention in the L’Oréal-UNESCO “For Women in Science” Award 2025. This honor recognizes her exceptional career & dedication to research in infectious diseases.
shorturl.at/Gfo4a
shorturl.at/Gfo4a
November 13, 2025 at 6:48 AM
👏👏👏
So proud of our co-PI!
This well-deserved recognition honors Luciana’s outstanding scientific contributions, her dedication to mentoring, and her support for young women in research. Please join me in congratulating her on this incredible achievement!
So proud of our co-PI!
This well-deserved recognition honors Luciana’s outstanding scientific contributions, her dedication to mentoring, and her support for young women in research. Please join me in congratulating her on this incredible achievement!
Reposted by Olivier Neyrolles
Un immense merci à nos doctorants, au comité organisateur et à nos orateurs invités @mblokesch.bsky.social, F. Mechta-Grigoriou & E. Crubezy, pour la réussite de ce superbe 10e Symposium des étudiants de l’IPBS.
Bravo à toutes et à tous !
Cap sur le 11e Symposium !
Bravo à toutes et à tous !
Cap sur le 11e Symposium !
November 5, 2025 at 2:06 PM
Un immense merci à nos doctorants, au comité organisateur et à nos orateurs invités @mblokesch.bsky.social, F. Mechta-Grigoriou & E. Crubezy, pour la réussite de ce superbe 10e Symposium des étudiants de l’IPBS.
Bravo à toutes et à tous !
Cap sur le 11e Symposium !
Bravo à toutes et à tous !
Cap sur le 11e Symposium !
Reposted by Olivier Neyrolles
A huge thank you to our PhD students, the organizing committee, and our guest speakers @mblokesch.bsky.social, F. Mechta-Grigoriou & E. Crubezy for making the 10th IPBS Student Symposium such a success.
Kudos to everyone involved!
On to the 11th Symposium! 🎉
Kudos to everyone involved!
On to the 11th Symposium! 🎉
November 5, 2025 at 2:07 PM
A huge thank you to our PhD students, the organizing committee, and our guest speakers @mblokesch.bsky.social, F. Mechta-Grigoriou & E. Crubezy for making the 10th IPBS Student Symposium such a success.
Kudos to everyone involved!
On to the 11th Symposium! 🎉
Kudos to everyone involved!
On to the 11th Symposium! 🎉
Reposted by Olivier Neyrolles
Exciting #postdoc opportunity in T. Gensollen's group!
How early-life interactions between the immune system and microbiota shape lifelong immune imprinting and disease risk
Learn more: shorturl.at/F8hqE
Deadline: January 15, 2026
Contact: recruit@ipbs.fr
#Immunology #Microbiology #Microbiota #Omics
How early-life interactions between the immune system and microbiota shape lifelong immune imprinting and disease risk
Learn more: shorturl.at/F8hqE
Deadline: January 15, 2026
Contact: recruit@ipbs.fr
#Immunology #Microbiology #Microbiota #Omics
Early-life Immune Imprinting and Inflammatory Diseases - IPBS-Toulouse
Our team studies neonatal immunity. We are particularly interested in mapping the mucosal cell subsets[…]
shorturl.at
November 4, 2025 at 5:32 AM
Exciting #postdoc opportunity in T. Gensollen's group!
How early-life interactions between the immune system and microbiota shape lifelong immune imprinting and disease risk
Learn more: shorturl.at/F8hqE
Deadline: January 15, 2026
Contact: recruit@ipbs.fr
#Immunology #Microbiology #Microbiota #Omics
How early-life interactions between the immune system and microbiota shape lifelong immune imprinting and disease risk
Learn more: shorturl.at/F8hqE
Deadline: January 15, 2026
Contact: recruit@ipbs.fr
#Immunology #Microbiology #Microbiota #Omics
Reposted by Olivier Neyrolles
Exciting #postdoc opportunity in KL Ung's group!
Understanding the molecular mechanisms of cell wall remodeling in pathogens
Learn more: shorturl.at/gPuFV
Deadline: January 15, 2026
Contact: recruit@ipbs.fr
#Protein #Biochemistry #StructuralBiology #Biophysics #CryoEM
Understanding the molecular mechanisms of cell wall remodeling in pathogens
Learn more: shorturl.at/gPuFV
Deadline: January 15, 2026
Contact: recruit@ipbs.fr
#Protein #Biochemistry #StructuralBiology #Biophysics #CryoEM
November 4, 2025 at 5:34 AM
Exciting #postdoc opportunity in KL Ung's group!
Understanding the molecular mechanisms of cell wall remodeling in pathogens
Learn more: shorturl.at/gPuFV
Deadline: January 15, 2026
Contact: recruit@ipbs.fr
#Protein #Biochemistry #StructuralBiology #Biophysics #CryoEM
Understanding the molecular mechanisms of cell wall remodeling in pathogens
Learn more: shorturl.at/gPuFV
Deadline: January 15, 2026
Contact: recruit@ipbs.fr
#Protein #Biochemistry #StructuralBiology #Biophysics #CryoEM
Reposted by Olivier Neyrolles
Insights from Andrea Cooper: Mtb drives expression of type I IFN–mediated #neutrophil accumulation, which limits interaction btwn CD4 T cells & macrophages. Failure to limit type I IFN very early in the process allows rapid progression of disease rupress.org/jem/article/...
#Tuberculosis
#Tuberculosis
October 28, 2025 at 4:01 PM
Insights from Andrea Cooper: Mtb drives expression of type I IFN–mediated #neutrophil accumulation, which limits interaction btwn CD4 T cells & macrophages. Failure to limit type I IFN very early in the process allows rapid progression of disease rupress.org/jem/article/...
#Tuberculosis
#Tuberculosis
Women's medicine, a 'bikini medicine'… « You do realize we have other organs too, right? »
That joke is so true, unfortunately!
✍️ Camille Van Belle
That joke is so true, unfortunately!
✍️ Camille Van Belle
October 29, 2025 at 9:29 AM
Women's medicine, a 'bikini medicine'… « You do realize we have other organs too, right? »
That joke is so true, unfortunately!
✍️ Camille Van Belle
That joke is so true, unfortunately!
✍️ Camille Van Belle
👏👏👏 Ophélie Dufrançais, @chrisverollet.bsky.social et leurs collègues ! Un travail soutenu par @frm-officiel.bsky.social et @agencerecherche.bsky.social et réalisé en collaboration avec @lp2mlab.bsky.social et @embl.org, entre autres.
Des chercheurs de l’IPBS (@chrisverollet.bsky.social et coll.) ont découvert que la protéine moésine régule les ostéoclastes, les cellules qui résorbent l’os. Sans elle, les os s’affaiblissent. Une piste prometteuse contre l’ #ostéoporose.
📘 @jcb.org shorturl.at/OhNSa
📘 @jcb.org shorturl.at/OhNSa
La protéine Moésine régule le remodelage osseux en modulant la fusion et l’activité des ostéoclastes - IPBS-Toulouse
Des chercheurs de l’Institut de Pharmacologie et Biologie Structurale (IPBS) ont mis en évidence un[…]
shorturl.at
October 27, 2025 at 5:32 PM
👏👏👏 Ophélie Dufrançais, @chrisverollet.bsky.social et leurs collègues ! Un travail soutenu par @frm-officiel.bsky.social et @agencerecherche.bsky.social et réalisé en collaboration avec @lp2mlab.bsky.social et @embl.org, entre autres.
Reposted by Olivier Neyrolles
Des chercheurs de l’IPBS (@chrisverollet.bsky.social et coll.) ont découvert que la protéine moésine régule les ostéoclastes, les cellules qui résorbent l’os. Sans elle, les os s’affaiblissent. Une piste prometteuse contre l’ #ostéoporose.
📘 @jcb.org shorturl.at/OhNSa
📘 @jcb.org shorturl.at/OhNSa
La protéine Moésine régule le remodelage osseux en modulant la fusion et l’activité des ostéoclastes - IPBS-Toulouse
Des chercheurs de l’Institut de Pharmacologie et Biologie Structurale (IPBS) ont mis en évidence un[…]
shorturl.at
October 27, 2025 at 5:29 PM
Des chercheurs de l’IPBS (@chrisverollet.bsky.social et coll.) ont découvert que la protéine moésine régule les ostéoclastes, les cellules qui résorbent l’os. Sans elle, les os s’affaiblissent. Une piste prometteuse contre l’ #ostéoporose.
📘 @jcb.org shorturl.at/OhNSa
📘 @jcb.org shorturl.at/OhNSa
Reposted by Olivier Neyrolles
Too much cell fusion can break your bones, literally!
IPBS researchers @chrisverollet.bsky.social & coll. found that moesin keeps bone-resorbing cells (osteoclasts) in check.
Without it, bones weaken, a discovery that could inspire new #osteoporosis treatments.
📘 @jcb.org shorturl.at/N0Esc
IPBS researchers @chrisverollet.bsky.social & coll. found that moesin keeps bone-resorbing cells (osteoclasts) in check.
Without it, bones weaken, a discovery that could inspire new #osteoporosis treatments.
📘 @jcb.org shorturl.at/N0Esc
Moesin Protein Controls Bone Remodeling by Regulating Osteoclast Fusion and Function - IPBS-Toulouse
Researchers at the Institut de Pharmacologie et Biologie Structurale (IPBS) have uncovered a pivotal role[…]
www.ipbs.fr
October 27, 2025 at 5:17 PM
Too much cell fusion can break your bones, literally!
IPBS researchers @chrisverollet.bsky.social & coll. found that moesin keeps bone-resorbing cells (osteoclasts) in check.
Without it, bones weaken, a discovery that could inspire new #osteoporosis treatments.
📘 @jcb.org shorturl.at/N0Esc
IPBS researchers @chrisverollet.bsky.social & coll. found that moesin keeps bone-resorbing cells (osteoclasts) in check.
Without it, bones weaken, a discovery that could inspire new #osteoporosis treatments.
📘 @jcb.org shorturl.at/N0Esc
Reposted by Olivier Neyrolles
We are inviting applications for postdoctoral fellows in immunology of TB at the South African Tuberculosis Vaccine Initiative, University of Cape Town. For more information see the attached ad:
idm.uct.ac.za/media/739223
idm.uct.ac.za/media/739223
October 9, 2025 at 11:28 AM
We are inviting applications for postdoctoral fellows in immunology of TB at the South African Tuberculosis Vaccine Initiative, University of Cape Town. For more information see the attached ad:
idm.uct.ac.za/media/739223
idm.uct.ac.za/media/739223
Reposted by Olivier Neyrolles
Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here:
emploi.cnrs.fr/Offres/Docto...
emploi.cnrs.fr/Offres/Docto...
Portail Emploi CNRS - Offre d'emploi - Thèse en Microbiologie-Biochimie (H/F)
emploi.cnrs.fr
October 9, 2025 at 12:18 PM
Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here:
emploi.cnrs.fr/Offres/Docto...
emploi.cnrs.fr/Offres/Docto...
This!👇
Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here:
emploi.cnrs.fr/Offres/Docto...
emploi.cnrs.fr/Offres/Docto...
Portail Emploi CNRS - Offre d'emploi - Thèse en Microbiologie-Biochimie (H/F)
emploi.cnrs.fr
October 9, 2025 at 7:39 PM
This!👇
What a fantastic event! Thanks to @carobarisch.bsky.social, Oliver Jäckle-Tietjen, and the amazing students for the kind invite and great organization. Such a pleasure to join! 🤩
@fzborstel.bsky.social
@fzborstel.bsky.social
Yesterday’s NGMI3 symposium @fzborstel.bsky.social was a real highlight 🎉 Great keynotes, inspiring discussions & a lot of fun! Many thanks to #NDI3, #Nordinfect & Oliver JT who did such a great job👏
@oneyrolles.bsky.social, @maxgg.bsky.social, Susanne Häussler, Silke Meiners & Christian Karsten!
@oneyrolles.bsky.social, @maxgg.bsky.social, Susanne Häussler, Silke Meiners & Christian Karsten!
October 9, 2025 at 5:33 PM
What a fantastic event! Thanks to @carobarisch.bsky.social, Oliver Jäckle-Tietjen, and the amazing students for the kind invite and great organization. Such a pleasure to join! 🤩
@fzborstel.bsky.social
@fzborstel.bsky.social
What an honor and joy to speak at Borsteler Herrenhaus for #NDI3 2025! Thrilled to reconnect with friends & colleagues. Special thanks to the brilliant students and @carobarisch.bsky.social for the kind invite & flawless organization!
#Immunology #InfectionBiology #NordInfect
Fotos: Kerstin Pukall
#Immunology #InfectionBiology #NordInfect
Fotos: Kerstin Pukall
October 8, 2025 at 6:52 PM
What an honor and joy to speak at Borsteler Herrenhaus for #NDI3 2025! Thrilled to reconnect with friends & colleagues. Special thanks to the brilliant students and @carobarisch.bsky.social for the kind invite & flawless organization!
#Immunology #InfectionBiology #NordInfect
Fotos: Kerstin Pukall
#Immunology #InfectionBiology #NordInfect
Fotos: Kerstin Pukall
Reposted by Olivier Neyrolles
A big thank you to our Scientific Advisory Board for their engagement during out meeting this week. So many thoughtful questions and insightful comments!
Hans-Georg Kräusslich, @oneyrolles.bsky.social,
@sykhalid.bsky.social, @thamlab.bsky.social,
Joost Enninga, Friedrich Förster, Ilaria Ferlenghi
Hans-Georg Kräusslich, @oneyrolles.bsky.social,
@sykhalid.bsky.social, @thamlab.bsky.social,
Joost Enninga, Friedrich Förster, Ilaria Ferlenghi
October 8, 2025 at 10:52 AM
A big thank you to our Scientific Advisory Board for their engagement during out meeting this week. So many thoughtful questions and insightful comments!
Hans-Georg Kräusslich, @oneyrolles.bsky.social,
@sykhalid.bsky.social, @thamlab.bsky.social,
Joost Enninga, Friedrich Förster, Ilaria Ferlenghi
Hans-Georg Kräusslich, @oneyrolles.bsky.social,
@sykhalid.bsky.social, @thamlab.bsky.social,
Joost Enninga, Friedrich Förster, Ilaria Ferlenghi
Welcome to the little blue planet @khadershabaana.bsky.social 😉
October 5, 2025 at 2:55 PM
Welcome to the little blue planet @khadershabaana.bsky.social 😉
Reposted by Olivier Neyrolles
#ResultatScientifique🔎| Un transporteur spécifique du bacille de la tuberculose pourrait être la cible de médicaments ?
✍️ @oneyrolles.bsky.social
🤝 @ipbstoulouse.bsky.social
📕 @pnas.org | buff.ly/XAynagm
✍️ @oneyrolles.bsky.social
🤝 @ipbstoulouse.bsky.social
📕 @pnas.org | buff.ly/XAynagm
Un point faible du bacille de la tuberculose identifié
Dans une étude parue dans PNAS, des scientifiques dévoilent que la survie d
buff.ly
September 23, 2025 at 2:01 PM
#ResultatScientifique🔎| Un transporteur spécifique du bacille de la tuberculose pourrait être la cible de médicaments ?
✍️ @oneyrolles.bsky.social
🤝 @ipbstoulouse.bsky.social
📕 @pnas.org | buff.ly/XAynagm
✍️ @oneyrolles.bsky.social
🤝 @ipbstoulouse.bsky.social
📕 @pnas.org | buff.ly/XAynagm
Very happy to have attended the inaugural lecture of the 20th congress of the @sfmicrobiologie.bsky.social by my former PhD supervisor, @alainblanchard.bsky.social.
Brilliant and moving 🙏🙏🙏
Brilliant and moving 🙏🙏🙏
September 24, 2025 at 4:24 PM
Very happy to have attended the inaugural lecture of the 20th congress of the @sfmicrobiologie.bsky.social by my former PhD supervisor, @alainblanchard.bsky.social.
Brilliant and moving 🙏🙏🙏
Brilliant and moving 🙏🙏🙏
Excited to share Wendy Le Mouëllic’s PhD work, now published in @pnas.org!
It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance.
Huge congrats to Wendy & colleagues!
shorturl.at/WbFQC
It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance.
Huge congrats to Wendy & colleagues!
shorturl.at/WbFQC
Inorganic sulfate is critical for Mycobacterium tuberculosis lung tissue colonization and redox balance | PNAS
Tuberculosis remains the deadliest infectious disease caused by a single pathogen,
highlighting the urgent need for novel therapies. A deeper under...
www.pnas.org
September 23, 2025 at 3:32 AM
Excited to share Wendy Le Mouëllic’s PhD work, now published in @pnas.org!
It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance.
Huge congrats to Wendy & colleagues!
shorturl.at/WbFQC
It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance.
Huge congrats to Wendy & colleagues!
shorturl.at/WbFQC
Another memorable #TBVACHORIZON WP1 working group meeting in Basel, Switzerland! Grateful to #TBVI and many thanks to Daniel Pinschewer and colleagues for the warm welcome and inspiring discussions.
@unibas.ch @horizoneu.bsky.social
@unibas.ch @horizoneu.bsky.social
September 19, 2025 at 11:45 AM
Another memorable #TBVACHORIZON WP1 working group meeting in Basel, Switzerland! Grateful to #TBVI and many thanks to Daniel Pinschewer and colleagues for the warm welcome and inspiring discussions.
@unibas.ch @horizoneu.bsky.social
@unibas.ch @horizoneu.bsky.social
Reposted by Olivier Neyrolles
We are looking to hire post-docs to work on T cell responses to M. tuberculosis infection using murine and NHP models. If you know T cells and wanna work on the top global infectious killer check us out. BSL3 experience not required. The NIH intramural program in Bethesda MD is an amazing place!
September 17, 2025 at 5:50 PM
We are looking to hire post-docs to work on T cell responses to M. tuberculosis infection using murine and NHP models. If you know T cells and wanna work on the top global infectious killer check us out. BSL3 experience not required. The NIH intramural program in Bethesda MD is an amazing place!
Reposted by Olivier Neyrolles
A 2-year postdoc position in my lab, under the supervision of P-Alex Kaminski, on Z-DNA phages and the benefit given by ZTGC DNA and the replication machinery, with attempt to create a Z based minireplicon
research.pasteur.fr/en/job/a-two...
research.pasteur.fr/en/job/a-two...
A two year post-doctoral position at the BacterialGenome Plasticity Unit starting October 1st - Research
research.pasteur.fr
July 28, 2025 at 10:30 AM
A 2-year postdoc position in my lab, under the supervision of P-Alex Kaminski, on Z-DNA phages and the benefit given by ZTGC DNA and the replication machinery, with attempt to create a Z based minireplicon
research.pasteur.fr/en/job/a-two...
research.pasteur.fr/en/job/a-two...
Reposted by Olivier Neyrolles
From tuberculosis to rheumatoid arthritis: A glycobiology breakthrough enters the valorization phase
👏 @yoannrombouts.bsky.social
Thanks @frm-officiel.bsky.social
More info: shorturl.at/i3sQd
👏 @yoannrombouts.bsky.social
Thanks @frm-officiel.bsky.social
More info: shorturl.at/i3sQd
July 29, 2025 at 9:40 AM
From tuberculosis to rheumatoid arthritis: A glycobiology breakthrough enters the valorization phase
👏 @yoannrombouts.bsky.social
Thanks @frm-officiel.bsky.social
More info: shorturl.at/i3sQd
👏 @yoannrombouts.bsky.social
Thanks @frm-officiel.bsky.social
More info: shorturl.at/i3sQd