Are you interested in cytoskeleton and looking for a postdoc position? I will be advertising positions in the new year but happy to chat in person if you are attending ASCB @ascbiology.bsky.social in Philadelphia. Just drop me a line.

SPIN90 and #YanCao strike again! First NPF to only activate a subset of Arp2/3 iso-complexes to regulate lamellipodial actin & protrusion efficiency. Great collaboration with @romet-jegou-lab.bsky.social #ManosMavrakis polarized fluorescence microscopy rocks 🤘💥🎉
www.biorxiv.org/content/10.6...

Researchers at the Crick have discovered that mice lacking a specific gene responsible for cell structure lose intestinal balance and experience systemic inflammation, mirroring a lethal condition seen in humans.

www.crick.ac.uk/news/2025-11...

This is a tale of precise team work, massive two way knowledge exchange and such an amazing support from immunologist and cell biologists at the Crick. I am pleased to see that our work is finally out and that all effort made in the Way Lab is being recognised! #actin #rare-disease #host-microbe

Our paper on Arp2/3-mediated bidirectional actin assembly is out @natsmb.nature.com 🚀 After great reviews & community feedback, this version includes new insights beyond the preprint:) Huge thanks to all co-authors!!! @drmichaelway.bsky.social @romet-jegou-lab.bsky.social @carolynmoores1.bsky.social

Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social

We are delighted to share our new preprint “The evolution of gene regulatory programs controlling gonadal development in primates” www.biorxiv.org/content/10.1...

🚨 New preprint!
Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM
www.biorxiv.org/content/10.1...

Registration is now open for NeuroBioUK 2025!
This year we're looking forward to hearing from our plenary speaker @cathyabbott.bsky.social. As ever, all other talks chosen from submitted abstracts so get submitting - we can't wait to see you there!

neurobiouk.sites.sheffield.ac.uk/registration

The longer we have worked on and refined this #microtubule - based model of #neurodegeneration, the more convincing it becomes. It is the fruit of 20 years of work. If you are interested, join my THE CYTOSKELETON OF NEURONS AND GLIA online talk this Thurday: ncytoskeleton.wixsite.com/webinars

We’re excited to share the first publication from our lab, now out in @EMBOPress! @shayma-a.bsky.social @ucl.ac.uk
Using live imaging in the mouse embryo, we tracked how heart progenitors migrate and assemble into the heart tube.

Featured in The Guardian! www.theguardian.com/science/2025...

New lab preprint! Unveiling the Molecular Architecture of T Cells and Immune Synapses with Cryo-Expansion Microscopy (Cryo-ExM). A fantastic collaboration with Dr. Benita Wolf. Congratulations to all authors, especially Florent Lemaitre, for leading this amazing work! www.biorxiv.org/content/10.1...

deadline early bird registration approaching soon for ACTIN ASSEMBLY FOR INTRACELLULAR FUNCTION 2025
aaif2025-szeged.hu/registration/

Do you want to hear the latest and greatest about the neuronal cytoskeleton? Join us in Chile next April for #NeuroCyto2025, organized by @monicamsousa.bsky.social, Kassandra Ori-McKenney and Tomás Falzone! Registration is open until March 5: neurocytoskeleton.com/2025/

Working on actin cytoskeleton and Arp2/3 complex? Check out our latest work～https://www.biorxiv.org/content/10.1101/2025.01.31.635869v1
In this work, we found SPIN90 forms a dimer, facilitating bidirectional actin filament nucleation by activating two Arp2/3 complex #Cryo-EM #Actin #Arp2/3

Arp2/3 nucleates bidirectional linear actin filaments when activated by SPIN90 !!! www.biorxiv.org/content/10.1...