kenzo ivanovitch
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kenzoivanovitch.bsky.social
kenzo ivanovitch
@kenzoivanovitch.bsky.social
Developmental Biologist @UCL
https://www.ivanovitch-lab.com
Pinned
We’re excited to share the first publication from our lab, now out in @EMBOPress! @shayma-a.bsky.social @ucl.ac.uk
Using live imaging in the mouse embryo, we tracked how heart progenitors migrate and assemble into the heart tube.
Early coordination of cell migration and cardiac fate determination during mammalian gastrulation, revealed by light-sheet microscopy tracking of individual mesodermal cells
#RefereedPreprint c/o @reviewcommons.org by @kenzoivanovitch.bsky.social and colleagues
www.embopress.org/doi/full/10....
Reposted by kenzo ivanovitch
v sad to hear Antonio García-Bellido's passing. his work on mitotic clones led to fundamental insights such as compartment boundaries, enabled post-embryonic analysis of lethals, and revealed autonomous vs non-autonomous effects of mutants. and founding father of Spanish DB and Drosophila schools.🪰
The European Drosophila Society #flyEDS extends the condolences on the passing of Antonio García-Bellido, considered the founder of the Spanish school of #Drosophila genetics and an influential figure in developmental biology research worldwide. May he rest in peace.
November 12, 2025 at 5:08 PM
Reposted by kenzo ivanovitch
Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social

We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇

www.biorxiv.org/content/10.1...
Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcoding
The formation of neural circuits depends on the precise spatial and temporal organisation of neuronal populations during development. In the vertebrate spinal cord, progenitors are patterned into mole...
www.biorxiv.org
October 26, 2025 at 5:15 PM
Reposted by kenzo ivanovitch
Out @natcomms.nature.com:
our work on how the ❤️-supporting pericardium forms & acts in pediatric heart conditions.🎈🫀

Expanding our preprint & with our first HCR (thx to @thelovelylab.bsky.social!).

Congrats all! #devbio #zebrafish #CHD @cupediatrics.bsky.social @cudevbio.bsky.social
rdcu.be/eIJm5
September 30, 2025 at 5:55 PM
Reposted by kenzo ivanovitch
🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x
September 22, 2025 at 9:37 AM
Reposted by kenzo ivanovitch
Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️
August 11, 2025 at 1:18 PM
Reposted by kenzo ivanovitch
Excited to share our latest work with @jamesbriscoe.bsky.social .

A global #cis-regulatory temporal program guides how spatial cues are interpreted in neural progenitors. We show how #space and #time can be integrated to generate cell type diversity in the #spinalcord.

Congrats to all authors.
July 21, 2025 at 10:18 AM
Reposted by kenzo ivanovitch
This isn't a coincidence, IMO. The fly community is generally super rigorous - because there are so many tools and techniques available, people expect you to really nail things in order to get published (and keep getting funded)
July 16, 2025 at 7:17 PM
Reposted by kenzo ivanovitch
[0/8] Stoked to share our work with @arjunraj.bsky.social on tissue organization in the gastruloid. We use lineage tracing and spatial transcriptomics to show that diversity among stem cell clones promotes, rather than hinders, gastruloid development: www.biorxiv.org/content/10.1...
Gastruloid patterning reflects division of labor among biased stem cell clones
Embryonic development typically requires precise coordination among cells to achieve reproducible outcomes, leading to the assumption that cellular heterogeneity must be minimized or buffered against....
www.biorxiv.org
July 15, 2025 at 3:44 PM
Reposted by kenzo ivanovitch
Interested in developmental epigenetics? So are we! Apply now to join us for your postdoc!

Multiple positions across multiple groups @mrc-lms.bsky.social

Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇

lms.mrc.ac.uk/work/vacanci...
MRC Postdoctoral Research Scientists x 5 - MRC Laboratory of Medical Sciences
Applications are now open for up to five postdoctoral positions in the area of developmental epigenetics.
lms.mrc.ac.uk
July 14, 2025 at 5:15 PM
Reposted by kenzo ivanovitch
We've just been awarded a grant to study the cellular basis of regeneration – to track the progenitors of sensory organs in the context of leg regeneration, in our favourite crustacean tinyurl.com/parhyale, based on live imaging and cell tracking. The project involves some cool collaborations... 1/3
July 13, 2025 at 2:55 PM
Reposted by kenzo ivanovitch
Want to hear more about bioimaging and image analysis at UCL? Follow @biig-ucl.bsky.social
This is a wonderful community for those bioimaging enthusiasts!
June 26, 2025 at 8:15 AM
Reposted by kenzo ivanovitch
Embryonic CX3CR1+ cells constitute a multipotent epiblast-derived progenitor population that contributes not only to the formation of tissue-resident macrophages, but also of cardiomyocytes and heart endothelial cells
Young-sup Yoon and coworkers
www.embopress.org/doi/full/10....
June 24, 2025 at 7:55 AM
Reposted by kenzo ivanovitch
Issue 12:
Commentary: in vivo metabolomics in the cancer clinic
Review: oxygen-sulfur interdependence
ADP-ribosylation in M.tuberculosis
Microprotein promoting BAT thermogenesis
Cover by @kenzoivanovitch.bsky.social and colleagues
www.embopress.org/toc/14602075...
June 23, 2025 at 6:53 AM
Reposted by kenzo ivanovitch
Save the date! March 23-26 will be the dates for our 2026 @bsdb.bsky.social annual meeting: Molecules to Morphogenesis!

Excited to reveal more details soon!

Want to attend with a reduced rate, and have access to conference/travel grants for other meetings too? Don't forget to join the BSDB :)
June 18, 2025 at 2:29 PM
Reposted by kenzo ivanovitch
Very happy to share I've written a review on placental vascular formation in mice and humans, now published in @dev-journal.bsky.social.

journals.biologists.com/dev/article/...

@idrm.ox.ac.uk Funded by the @thebhf.bsky.social
Feto-placental blood vessel development
Summary: This Review contains an overview of placental vascular development and pathologies in mice and humans and highlights key remaining questions in the field.
journals.biologists.com
June 2, 2025 at 10:24 AM
Reposted by kenzo ivanovitch
Beautiful work from @sagnera.bsky.social & co on how spinal neurons diversify

A temporal TF clock in spinal neurons, sequentially specifying different motor and sensory neuron subtypes during development

A shared molecular timer driving cellular diversity

www.biorxiv.org/cgi/content/...
www.biorxiv.org
May 29, 2025 at 6:29 AM
May 19, 2025 at 9:03 PM
Reposted by kenzo ivanovitch
Researchers @uclpophealthsci.bsky.social and @crick.ac.uk, led by Dr @kenzoivanovitch.bsky.social & Shayma Abukar, have, for the first time, identified the origin of cardiac cells using 3D images of a heart forming in real-time, inside a living mouse embryo www.ucl.ac.uk/news/2025/ma...
May 13, 2025 at 10:07 AM
We’re excited to share the first publication from our lab, now out in @EMBOPress! @shayma-a.bsky.social @ucl.ac.uk
Using live imaging in the mouse embryo, we tracked how heart progenitors migrate and assemble into the heart tube.
Early coordination of cell migration and cardiac fate determination during mammalian gastrulation, revealed by light-sheet microscopy tracking of individual mesodermal cells
#RefereedPreprint c/o @reviewcommons.org by @kenzoivanovitch.bsky.social and colleagues
www.embopress.org/doi/full/10....
May 13, 2025 at 5:30 PM
Reposted by kenzo ivanovitch
Fresh from the press! @lankylaste.bsky.social, @guijacquemet.bsky.social and I put together a practical guide on how to develop software for life science applications.
Practical recommendations for developing software for life science applications
ABSTRACT. Developing user-friendly image analysis software is essential for advancing biological and life science research. However, the interdisciplinary gap between software developers and life scie...
doi.org
March 17, 2025 at 9:44 AM
Reposted by kenzo ivanovitch
We’re hiring a new research fellow. Come join us in London to study glial cells in the ageing retina using killifish as a model. www.ucl.ac.uk/work-at-ucl/...
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
www.ucl.ac.uk
February 7, 2025 at 2:35 PM
Reposted by kenzo ivanovitch
In Praise of Peer Review

As an Editor of the journal Development, I often hear complaints about peer review. We all know the problems - from lengthy review times to requests for seemingly unnecessary experiments. I agree with many of these complaints. Katherine Brown (Executive Editor of…
In Praise of Peer Review
As an Editor of the journal Development, I often hear complaints about peer review. We all know the problems - from lengthy review times to requests for seemingly unnecessary experiments. I agree with many of these complaints. Katherine Brown (Executive Editor of Development) and I recently wrote an editorial about this in which we talk about some of the things Development is doing to mitigate the worst of the problems.
briscoelab.org
December 11, 2024 at 9:03 AM
Reposted by kenzo ivanovitch
New @dev-journal.bsky.social editorial

We know we have high standards - but we're committed to making publishing with us constructive

From clear revision guidance to limitations sections & transparent peer review, we're here to help you share your science

journals.biologists.com/dev/article/...
Constructive Critics: Development's approach to peer review
We're all familiar with complaints about peer review. Some think it's biased – editors (especially from ‘those’ journals) seem to have too much power to decide what gets published. It can be opaque – ...
journals.biologists.com
December 2, 2024 at 9:19 AM
Reposted by kenzo ivanovitch
Using #gastruloids F. Lescroart and colleagues explore the origins of the most complex organ in our body, the #heart. Very good start of unravelling an amazing process in which an organ is being designed and redesigned at the same time it functions
www.nature.com/articles/s41...
November 28, 2024 at 6:42 AM