Tianyang Liu
@tianyang22.bsky.social
Postdoc @Moores Lab in London. Interested in cytoskeleton and cryoEM🐍🐍🐍
Reposted by Tianyang Liu
Now for something completely different - Way lab does immunology - check out our @science.org paper - Branched actin networks mediate macrophage-dependent host-microbiota homeostasis. The work was driven by the 2 first authors @luiz90vasc.bsky.social @shainahuang.bsky.social
November 14, 2025 at 9:16 AM
Now for something completely different - Way lab does immunology - check out our @science.org paper - Branched actin networks mediate macrophage-dependent host-microbiota homeostasis. The work was driven by the 2 first authors @luiz90vasc.bsky.social @shainahuang.bsky.social
Our paper on Arp2/3-mediated bidirectional actin assembly is out @natsmb.nature.com 🚀 After great reviews & community feedback, this version includes new insights beyond the preprint:) Huge thanks to all co-authors!!! @drmichaelway.bsky.social @romet-jegou-lab.bsky.social @carolynmoores1.bsky.social
And now for something completely different @tianyang22.bsky.social & #YanCao uncover of how SPIN90 dimers activate Arp2/3 to nucleate bidirectional linear actin filaments. Great collaboration with @romet-jegou-lab.bsky.social & @carolynmoores1.bsky.social #Cryo-EM #Arp2/3 rdcu.be/eGoH4
Arp2/3-mediated bidirectional actin assembly by SPIN90 dimers
Nature Structural & Molecular Biology - Liu et al. show that SPIN90 dimerizes and binds two Arp2/3 complexes to nucleate two bidirectional actin filaments and the dimerization domain is...
rdcu.be
September 16, 2025 at 8:20 PM
Our paper on Arp2/3-mediated bidirectional actin assembly is out @natsmb.nature.com 🚀 After great reviews & community feedback, this version includes new insights beyond the preprint:) Huge thanks to all co-authors!!! @drmichaelway.bsky.social @romet-jegou-lab.bsky.social @carolynmoores1.bsky.social
Reposted by Tianyang Liu
Another wonderful collaboration with @alanbrownhms.bsky.social lab 👇
Zhang lab (co-first author @qingweiniu.bsky.social) contribute the doublet structure from Crithidia fasciculata, a model organism that infects mosquitoes.
Zhang lab (co-first author @qingweiniu.bsky.social) contribute the doublet structure from Crithidia fasciculata, a model organism that infects mosquitoes.
I am super excited to share our latest work on the structures of doublet microtubules from trypanosomatid parasites, the causative agents of leishmaniasis, Chagas disease, and African sleeping sickness. tinyurl.com/48sh3xn5
Evolutionary adaptations of doublet microtubules in trypanosomatid parasites
The movement and pathogenicity of trypanosomatid species, the causative agents of trypanosomiasis and leishmaniasis, are dependent on a flagellum that contains an axoneme of dynein-bound doublet micro...
tinyurl.com
March 13, 2025 at 10:41 PM
Another wonderful collaboration with @alanbrownhms.bsky.social lab 👇
Zhang lab (co-first author @qingweiniu.bsky.social) contribute the doublet structure from Crithidia fasciculata, a model organism that infects mosquitoes.
Zhang lab (co-first author @qingweiniu.bsky.social) contribute the doublet structure from Crithidia fasciculata, a model organism that infects mosquitoes.
Reposted by Tianyang Liu
Excited to announce the 10th "Choanoflagellates & Friends Workshop" over May 20-22 in our own Institut Pasteur in Paris: 2025choanocon.wordpress.com Registrations open til March 15, abstract til March 5. Pre-conference event for students/postdocs on 19/05. Plenty of slots for selected talks/posters!
February 17, 2025 at 11:41 AM
Excited to announce the 10th "Choanoflagellates & Friends Workshop" over May 20-22 in our own Institut Pasteur in Paris: 2025choanocon.wordpress.com Registrations open til March 15, abstract til March 5. Pre-conference event for students/postdocs on 19/05. Plenty of slots for selected talks/posters!
Working on actin cytoskeleton and Arp2/3 complex? Check out our latest work～https://www.biorxiv.org/content/10.1101/2025.01.31.635869v1
In this work, we found SPIN90 forms a dimer, facilitating bidirectional actin filament nucleation by activating two Arp2/3 complex #Cryo-EM #Actin #Arp2/3
In this work, we found SPIN90 forms a dimer, facilitating bidirectional actin filament nucleation by activating two Arp2/3 complex #Cryo-EM #Actin #Arp2/3
January 31, 2025 at 9:42 PM