Matt Sikora
@mjsikora.bsky.social
Assoc Prof at CU Anschutz, Cancer biologist, focus on #lobular breast cancer and gyn cancers, estrogen receptor pharmacology, and basic mechs in cancer disparities. Posts are my own. He/Him.
www.sikoralab.com
www.sikoralab.com
Pinned
Matt Sikora
@mjsikora.bsky.social
· Nov 25
Home
welcome to the sikora lab
www.sikoralab.com
Hey #oncosky and 🧪 friends - so glad you're here!
A quick (re)intro to the Sikora Lab (www.sikoralab.com):
We study:
1) #lobular breast cancer and its complicated relationship w estrogen.
2) gyn / ovarian cancer, metabolic parallels w #lobular, and genetic links to health disparities.
1/n
A quick (re)intro to the Sikora Lab (www.sikoralab.com):
We study:
1) #lobular breast cancer and its complicated relationship w estrogen.
2) gyn / ovarian cancer, metabolic parallels w #lobular, and genetic links to health disparities.
1/n
Reposted by Matt Sikora
Save the date: our faculty job market series continues this Wed, Nov12 at 3pm ET / 12p PT!
Topic: on-site interviews + seminars
Come hear our junior faculty share our thoughts/advice! There will also be time for Q&A.
Registration link in flyer - see you soon!
Topic: on-site interviews + seminars
Come hear our junior faculty share our thoughts/advice! There will also be time for Q&A.
Registration link in flyer - see you soon!
November 10, 2025 at 7:28 PM
Save the date: our faculty job market series continues this Wed, Nov12 at 3pm ET / 12p PT!
Topic: on-site interviews + seminars
Come hear our junior faculty share our thoughts/advice! There will also be time for Q&A.
Registration link in flyer - see you soon!
Topic: on-site interviews + seminars
Come hear our junior faculty share our thoughts/advice! There will also be time for Q&A.
Registration link in flyer - see you soon!
Reposted by Matt Sikora
Reposted by Matt Sikora
Are you a #Colorado resident who buys health insurance on the state marketplace (Connect for Health Colorado) & have seen a spike in your premiums for next year? DM me if you're willing to talk about the bill. Thanks! #copolitics
November 6, 2025 at 3:38 PM
Are you a #Colorado resident who buys health insurance on the state marketplace (Connect for Health Colorado) & have seen a spike in your premiums for next year? DM me if you're willing to talk about the bill. Thanks! #copolitics
Reposted by Matt Sikora
Reposted by Matt Sikora
Beshear: Let me be clear. The president has both the funding and the authority to fund snap during a shutdown. In fact, every other president in every other shutdown has done so. People going hungry in this instance is a choice that this president has made.
November 5, 2025 at 4:44 PM
Beshear: Let me be clear. The president has both the funding and the authority to fund snap during a shutdown. In fact, every other president in every other shutdown has done so. People going hungry in this instance is a choice that this president has made.
For Halloween, the Sikora Lab is excited to announce the release of the debut self-titled album from **MITOTIC CATASTROPHE** with chart topping hits:
- Pour Some Agar on Me
- You Give Science a Bad Name
- Sweet Graph 'o Mine
- We're Not Gonna Fake it
- Welcome to the Data
- Back in Lab
Rock on!!!
- Pour Some Agar on Me
- You Give Science a Bad Name
- Sweet Graph 'o Mine
- We're Not Gonna Fake it
- Welcome to the Data
- Back in Lab
Rock on!!!
October 30, 2025 at 8:28 PM
For Halloween, the Sikora Lab is excited to announce the release of the debut self-titled album from **MITOTIC CATASTROPHE** with chart topping hits:
- Pour Some Agar on Me
- You Give Science a Bad Name
- Sweet Graph 'o Mine
- We're Not Gonna Fake it
- Welcome to the Data
- Back in Lab
Rock on!!!
- Pour Some Agar on Me
- You Give Science a Bad Name
- Sweet Graph 'o Mine
- We're Not Gonna Fake it
- Welcome to the Data
- Back in Lab
Rock on!!!
Reposted by Matt Sikora
Endocrine research conference: Dr Maggie Musick from the Sikora lab @mjsikora.bsky.social discussed mechanisms of tumorigenesis in lobular breast cancer.
#cancer #CUPathology
#cancer #CUPathology
October 22, 2025 at 6:01 PM
Endocrine research conference: Dr Maggie Musick from the Sikora lab @mjsikora.bsky.social discussed mechanisms of tumorigenesis in lobular breast cancer.
#cancer #CUPathology
#cancer #CUPathology
I know & trust that NIH staff will get this round of reviews done. Yet having done my own CSR reviews 'for nothing' & with my own R01 sitting unreviewed now, working on another NIH grant has never felt so painful and futile. A quiet impact on science, perhaps, robbing the joy from looking ahead.
If you are serving on NIH study sections that have been cancelled, PLEASE continue to work on your reviews. NIH will do everything their power to ensure the meetings happen eventually, and the more prepared you are when those meetings are rescheduled, the better.
Welp. Thanks to the Republican gov shutdown I have a bunch of hours back in my week due to a NIH study section not meeting.
These poor applicants. They will be waiting week by week for government to reopen and to find out what will happen to their grant application.
These poor applicants. They will be waiting week by week for government to reopen and to find out what will happen to their grant application.
October 20, 2025 at 3:52 PM
I know & trust that NIH staff will get this round of reviews done. Yet having done my own CSR reviews 'for nothing' & with my own R01 sitting unreviewed now, working on another NIH grant has never felt so painful and futile. A quiet impact on science, perhaps, robbing the joy from looking ahead.
Reposted by Matt Sikora
. @cucancercenter.bsky.social member @mjsikora.bsky.social, PhD, is a leader in research into lobular breast cancer, an understudied cancer type that’s on the rise in American women and has sharply lower survival rates several years after diagnosis than more common breast cancers. #cucityofhealth
An Understudied Type of Breast Cancer Poses a Lurking Threat
Matt Sikora, PhD, seeks better answers for lobular breast cancer, which can be harder to detect & has lower survival rates after several years than other types.
news.cuanschutz.edu
October 13, 2025 at 7:11 PM
. @cucancercenter.bsky.social member @mjsikora.bsky.social, PhD, is a leader in research into lobular breast cancer, an understudied cancer type that’s on the rise in American women and has sharply lower survival rates several years after diagnosis than more common breast cancers. #cucityofhealth
Reposted by Matt Sikora
After Trump got his Covid shot, he chose to fire the scientists protecting the rest of us from diseases.
October 11, 2025 at 4:05 PM
After Trump got his Covid shot, he chose to fire the scientists protecting the rest of us from diseases.
Reposted by Matt Sikora
THAT’S NOT HOW IT WORKS
RFK Jr on Tylenol and autism: "It is not proof. We're doing the studies to make the proof."
October 9, 2025 at 5:11 PM
THAT’S NOT HOW IT WORKS
Reposted by Matt Sikora
Reposted by Matt Sikora
Sometimes I think about how from 1935-1975ish, Bell Labs produced an insane amount of revolutionary science and technology, including 11 Nobel Prizes, the transistor, UNIX, C, the laser, the solar cell, information theory, etc. The secret? Provide scientists with ample, steady, no-strings funding.
sites.stat.columbia.edu
October 4, 2025 at 5:35 PM
Sometimes I think about how from 1935-1975ish, Bell Labs produced an insane amount of revolutionary science and technology, including 11 Nobel Prizes, the transistor, UNIX, C, the laser, the solar cell, information theory, etc. The secret? Provide scientists with ample, steady, no-strings funding.
Reposted by Matt Sikora
I am just so fucking proud of her.
October 3, 2025 at 7:45 PM
I am just so fucking proud of her.
Reposted by Matt Sikora
NEWS: The F.D.A. approved a new generic version of the abortion pill mifepristone. www.nytimes.com/2025/10/02/h...
F.D.A. Approves Generic Abortion Pill as Opponents Push Trump for New Restrictions
www.nytimes.com
October 2, 2025 at 11:06 PM
NEWS: The F.D.A. approved a new generic version of the abortion pill mifepristone. www.nytimes.com/2025/10/02/h...
Reposted by Matt Sikora
Donald Trump is conditioning federal funding to universities on the signing of a loyalty pledge to his agenda.
This reeks of authoritarianism, and the universities should reject this hostage-taking of their funding.
This reeks of authoritarianism, and the universities should reject this hostage-taking of their funding.
Trump Administration Asks Colleges to Sign ‘Compact’ to Get Funding Preference
Demands sent to nine top schools included pledging to freeze tuition for five years and to commit to strict definitions of gender.
www.nytimes.com
October 2, 2025 at 8:11 PM
Donald Trump is conditioning federal funding to universities on the signing of a loyalty pledge to his agenda.
This reeks of authoritarianism, and the universities should reject this hostage-taking of their funding.
This reeks of authoritarianism, and the universities should reject this hostage-taking of their funding.
Reposted by Matt Sikora
The Jane Goodall Institute of Canada has learned this morning, Wednesday, October 1st, 2025, that Dr. Jane Goodall DBE, UN Messenger of Peace and Founder of the Jane Goodall Institute, has passed away due to natural causes.
She was in California as part of her speaking tour in the United States.
She was in California as part of her speaking tour in the United States.
October 1, 2025 at 6:14 PM
The Jane Goodall Institute of Canada has learned this morning, Wednesday, October 1st, 2025, that Dr. Jane Goodall DBE, UN Messenger of Peace and Founder of the Jane Goodall Institute, has passed away due to natural causes.
She was in California as part of her speaking tour in the United States.
She was in California as part of her speaking tour in the United States.
This is going to be the most unhinged well-being survey ever.
October 1, 2025 at 4:25 PM
This is going to be the most unhinged well-being survey ever.
Reposted by Matt Sikora
“The Founders understood that without education, the ability to repeat tyranny was too great. They pushed—whether it was Franklin, Washington, Madison, or Jefferson—in their writings for education, for critical thinking, & for an understanding of its role.”
— @rweingarten.bsky.social
— @rweingarten.bsky.social
September 30, 2025 at 4:44 PM
“The Founders understood that without education, the ability to repeat tyranny was too great. They pushed—whether it was Franklin, Washington, Madison, or Jefferson—in their writings for education, for critical thinking, & for an understanding of its role.”
— @rweingarten.bsky.social
— @rweingarten.bsky.social
This is right up there with interviewing Peter Navarro the other day - pandering to MAGA isn't going to get your funding back, NPR.
There is no 'both sides' to acetaminophen and autism, it's a safe drug during pregnancy.
There is no 'both sides' to acetaminophen and autism, it's a safe drug during pregnancy.
The science on Tylenol and autism isn't clear, despite President Trump's claims. Here's what parents need to know to make their own decisions about acetaminophen.
When it comes to Tylenol, what are parents to do?
The science on Tylenol and autism isn't clear, despite President Trump's claims. Here's what parents need to know to make their own decisions about acetaminophen.
n.pr
September 24, 2025 at 4:56 PM
This is right up there with interviewing Peter Navarro the other day - pandering to MAGA isn't going to get your funding back, NPR.
There is no 'both sides' to acetaminophen and autism, it's a safe drug during pregnancy.
There is no 'both sides' to acetaminophen and autism, it's a safe drug during pregnancy.
Reposted by Matt Sikora
I often get this question from non-scientists I meet when I travel, "why haven't we cured cancer yet?" and it does reveal a true disconnect between reality and public perception. You know who never asks me that question? Breast cancer patients and advocates I work with /1
Many types of cancer are now readily treatable, particularly if diagnosed early in their natural history. Much more remains to be done. But the “the cure for cancer” canard minimizes that progress from which many Americans and others around the globe have benefitted.
22/n
22/n
September 22, 2025 at 4:55 PM
I often get this question from non-scientists I meet when I travel, "why haven't we cured cancer yet?" and it does reveal a true disconnect between reality and public perception. You know who never asks me that question? Breast cancer patients and advocates I work with /1
Reposted by Matt Sikora
"STAT’s analysis of NIH Reporter data reveals that the agency will still fund far fewer new projects this year, due to a change in how it awards grants...the number of R grants issued has dropped much more precipitously — from 5,633 to
3,758 newly funded projects."
3,758 newly funded projects."
A frenzy of grantmaking in August has the NIH seemingly on pace to spend its entire $47 billion budget by the end of the fiscal year on Sept. 30
www.statnews.com/2025/09/12/n...
www.statnews.com/2025/09/12/n...
After lagging far behind, NIH now seems on pace to spend its entire $47 billion budget by Sept. 30
A frenzy of grantmaking in August has the NIH seemingly on pace to spend its entire $47 billion budget by the end of the fiscal year on Sept. 30
www.statnews.com
September 19, 2025 at 1:16 AM
"STAT’s analysis of NIH Reporter data reveals that the agency will still fund far fewer new projects this year, due to a change in how it awards grants...the number of R grants issued has dropped much more precipitously — from 5,633 to
3,758 newly funded projects."
3,758 newly funded projects."
Sigh. Our 8th percentile R21 officially misses the crazy 7%ile payline at NCI. At the same time, my R01 gets Y4-5 funded together, when instead of that multi-year funding, they could've funded new work on the R21!
September 16, 2025 at 3:12 PM
Sigh. Our 8th percentile R21 officially misses the crazy 7%ile payline at NCI. At the same time, my R01 gets Y4-5 funded together, when instead of that multi-year funding, they could've funded new work on the R21!
Reposted by Matt Sikora
While Health Secretary Robert F. Kennedy, Jr., dismantles the federal institutions that set vaccine policy, states like Colorado are changing laws and regulations in an effort to preserve access to vaccines.
Wary of RFK Jr., Colorado started revamping its vaccine policies last spring
While Health Secretary Robert F. Kennedy, Jr., dismantles the federal institutions that set vaccine policy, states like Colorado are changing laws and regulations in an effort to preserve access to vaccines.
n.pr
September 12, 2025 at 1:29 PM
While Health Secretary Robert F. Kennedy, Jr., dismantles the federal institutions that set vaccine policy, states like Colorado are changing laws and regulations in an effort to preserve access to vaccines.
NIH's NOSI on Women's Health Research was edited to expire as of yesterday, in case you were worried that the clowns in charge were finished axing research that they don't understand.
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
Expired NOT-OD-24-079: Notice of Special Interest: Womens Health Research
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Special Interest: Womens Health Research NOT-OD-24-079. ORWH
grants.nih.gov
September 10, 2025 at 7:35 PM
NIH's NOSI on Women's Health Research was edited to expire as of yesterday, in case you were worried that the clowns in charge were finished axing research that they don't understand.
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...