CMcG Rheum
@medicastra.medsky.social
#Hospital, #MD, #Rheumatology, UK based.
A chemistry PhD & pharma bg, came to medicine late
Scrolling is a distraction from taking action. Pick some concrete way to help & get to it.
@twofishnocat.bsky.social for the likes/hobbies stuff
A chemistry PhD & pharma bg, came to medicine late
Scrolling is a distraction from taking action. Pick some concrete way to help & get to it.
@twofishnocat.bsky.social for the likes/hobbies stuff
Reposted by CMcG Rheum
🧵 The ANA Test — Medicine’s Most Misinterpreted Marker
Up to 1 in 7 healthy adults test positive and never develop autoimmune disease.
Read the full post here:
🔗 haus.health/blog/ana-tes...
#Rheumatology #Autoimmune #Lupus #Medicine
Up to 1 in 7 healthy adults test positive and never develop autoimmune disease.
Read the full post here:
🔗 haus.health/blog/ana-tes...
#Rheumatology #Autoimmune #Lupus #Medicine
The ANA Test Explained: What a Positive Result Really Means — Haus Health Rheumatology
A rheumatologist explains why the ANA test is often misinterpreted—and what a positive result does (and doesn’t) mean for autoimmune disease.
haus.health
November 12, 2025 at 1:52 AM
🧵 The ANA Test — Medicine’s Most Misinterpreted Marker
Up to 1 in 7 healthy adults test positive and never develop autoimmune disease.
Read the full post here:
🔗 haus.health/blog/ana-tes...
#Rheumatology #Autoimmune #Lupus #Medicine
Up to 1 in 7 healthy adults test positive and never develop autoimmune disease.
Read the full post here:
🔗 haus.health/blog/ana-tes...
#Rheumatology #Autoimmune #Lupus #Medicine
Reposted by CMcG Rheum
GCA is a rare autoimmune disease that causes inflammation in the blood vessels — often leading to headaches, scalp tenderness, jaw pain when chewing, and in some cases, vision loss.
Awareness saves sight.
#GCAAwarenessDay #ChronicIllnessCommunity #InvisibleIllness #AutoimmuneWarrior #CreakyJoints
Awareness saves sight.
#GCAAwarenessDay #ChronicIllnessCommunity #InvisibleIllness #AutoimmuneWarrior #CreakyJoints
October 23, 2025 at 6:27 AM
GCA is a rare autoimmune disease that causes inflammation in the blood vessels — often leading to headaches, scalp tenderness, jaw pain when chewing, and in some cases, vision loss.
Awareness saves sight.
#GCAAwarenessDay #ChronicIllnessCommunity #InvisibleIllness #AutoimmuneWarrior #CreakyJoints
Awareness saves sight.
#GCAAwarenessDay #ChronicIllnessCommunity #InvisibleIllness #AutoimmuneWarrior #CreakyJoints
Random. Have you ever seen someone demoing a rowing machine with good form, without knees coming up before hands pass etc.
July 27, 2025 at 1:13 PM
Random. Have you ever seen someone demoing a rowing machine with good form, without knees coming up before hands pass etc.
Someone posted about their tachycardia moment.
Is anti-MDA5 associated ILD etc the ANCA positive ILD etc of this century?
Is anti-MDA5 associated ILD etc the ANCA positive ILD etc of this century?
February 15, 2025 at 2:25 PM
Someone posted about their tachycardia moment.
Is anti-MDA5 associated ILD etc the ANCA positive ILD etc of this century?
Is anti-MDA5 associated ILD etc the ANCA positive ILD etc of this century?
Reposted by CMcG Rheum
CIPS (Calcineurin Inhibitor-induced Pain Syndrome)
✅ Acute symmetric pain in transplant pts on CNI
✅ distal → proximal joints
✅ MRI: subchondral/periarticular edema; T1↓, T2↑
✅ Bone scan: calcaneal uptake↑
✅ Treatment: Ca channel blockers
#Rdiag #MSKRad #RadSky #MedSky
PMID: 23615775
✅ Acute symmetric pain in transplant pts on CNI
✅ distal → proximal joints
✅ MRI: subchondral/periarticular edema; T1↓, T2↑
✅ Bone scan: calcaneal uptake↑
✅ Treatment: Ca channel blockers
#Rdiag #MSKRad #RadSky #MedSky
PMID: 23615775
February 15, 2025 at 12:05 PM
Reposted by CMcG Rheum
In case you missed the poster session this morning #ISNWCN
APPEAR -C3G trial results showing promising at 12 months
✨Nice seeing @profnickwebb.bsky.social
APPEAR -C3G trial results showing promising at 12 months
✨Nice seeing @profnickwebb.bsky.social
February 8, 2025 at 5:25 AM
In case you missed the poster session this morning #ISNWCN
APPEAR -C3G trial results showing promising at 12 months
✨Nice seeing @profnickwebb.bsky.social
APPEAR -C3G trial results showing promising at 12 months
✨Nice seeing @profnickwebb.bsky.social
Reposted by CMcG Rheum
JOB ALERT FOR NEUROLOGY TRAINEES. On www.oriel.nhs.uk now. Academic Clinical Lecturer post in Dementia & Neurodegeneration @imperialbrains.bsky.social. Research can cover any aspect of the above. Please repost and feel free to contact me if interested (am at ABN SIG meeting today).
January 10, 2025 at 11:44 AM
JOB ALERT FOR NEUROLOGY TRAINEES. On www.oriel.nhs.uk now. Academic Clinical Lecturer post in Dementia & Neurodegeneration @imperialbrains.bsky.social. Research can cover any aspect of the above. Please repost and feel free to contact me if interested (am at ABN SIG meeting today).
Have definitely seen a few of these in #rheumatology as one of the painless lumpy bumpy things that we are asked about. There was a painful one though that spread under the hand flexor retinaculum. Pleased with the name change as the old one just never quite rolled off the tongue.
A right-handed man in his 50s presented with a painless, enlarging nodule destroying his nail. Biopsy confirmed a rare but locally aggressive tumor. What’s your diagnosis? #Dermatology #MedSky
Enlarging Painless Nodule Destroying Nail: What's Your Diagnosis?
A painless finger nodule leads to nail destruction, revealing an uncommon but locally aggressive tumor of the tendon sheath.
conexiant.com
February 6, 2025 at 10:43 AM
Have definitely seen a few of these in #rheumatology as one of the painless lumpy bumpy things that we are asked about. There was a painful one though that spread under the hand flexor retinaculum. Pleased with the name change as the old one just never quite rolled off the tongue.
From 2023, a nice discussion of retinal vein occlusions. I might always be on the lookout for #GCA but being clearer on the other options for painless vision loss is valuable.
lrn.peerview.com/150209033_1_...
lrn.peerview.com/150209033_1_...
MDADI
MDADI
lrn.peerview.com
February 5, 2025 at 9:28 AM
From 2023, a nice discussion of retinal vein occlusions. I might always be on the lookout for #GCA but being clearer on the other options for painless vision loss is valuable.
lrn.peerview.com/150209033_1_...
lrn.peerview.com/150209033_1_...
Holey monstera!!
ok ok here is the plant for all the sickos in my mentions asking for a photo!
February 4, 2025 at 4:06 PM
Holey monstera!!
That is very thought provoking. An #INR of 20.5, and such a high anti-TTG!!!
Coagulopathy of unknown etiology leading to a #celiacdisease diagnosis
#Medsky #Gastrosky
www.sciencedirect.com/science/arti...
#Medsky #Gastrosky
www.sciencedirect.com/science/arti...
Marked coagulopathy without liver disease or anticoagulation therapy
Symptomatic coagulopathies in celiac disease (CD) are rare. Here, we report a profound case of coagulopathy in a celiac. A 66-year old female without …
www.sciencedirect.com
February 3, 2025 at 8:30 PM
That is very thought provoking. An #INR of 20.5, and such a high anti-TTG!!!
Please, por favor, s'il vous plait, put something, anything in the profile spiel to catch the moucha.
February 3, 2025 at 6:06 PM
Please, por favor, s'il vous plait, put something, anything in the profile spiel to catch the moucha.
@benoitbrilland.bsky.social Could you add me to your starter list please
February 3, 2025 at 5:10 PM
@benoitbrilland.bsky.social Could you add me to your starter list please
Thanks, added this to my profile.
📢 Listen: scrolling is a distraction from taking action. Pick some concrete way to help large or small every day, & get to it. I asked our public school counselor Fri what she needs in our school’s free food pantry & just bought it. Be a helper.
#MedSky #HCWvsHunger #tariffs
#MedSky #HCWvsHunger #tariffs
February 3, 2025 at 9:13 AM
Thanks, added this to my profile.
Reposted by CMcG Rheum
Urine Protein Tests in Lupus: What do They Mean? | The Journal of Rheumatology https://buff.ly/3EhcTTl
Urine Protein Tests in Lupus: What do They Mean?
The development of nephritis in patients with lupus is associated with increased morbidity and mortality. Proteinuria is a key indicator of kidney involvement detecting and monitoring proteinuria is…
buff.ly
February 2, 2025 at 2:53 PM
Urine Protein Tests in Lupus: What do They Mean? | The Journal of Rheumatology https://buff.ly/3EhcTTl
Reposted by CMcG Rheum
Bosentan protective in development of PAH in SSc patients??
#systemicsclerosis #scleroderma #rheumsky
www.jrheum.org/content/earl...
#systemicsclerosis #scleroderma #rheumsky
www.jrheum.org/content/earl...
Pulmonary Arterial Hypertension Incidence in Patients With Systemic Sclerosis Treated With Bosentan for Digital Ulcers: Evidence From the SPRING-SIR Registry
Objective Bosentan (BOS) is approved for treating pulmonary arterial hypertension (PAH) and preventing digital ulcers (DU) in systemic sclerosis (SSc). Our study aimed to evaluate whether BOS prescrib...
www.jrheum.org
February 2, 2025 at 1:20 AM
Bosentan protective in development of PAH in SSc patients??
#systemicsclerosis #scleroderma #rheumsky
www.jrheum.org/content/earl...
#systemicsclerosis #scleroderma #rheumsky
www.jrheum.org/content/earl...
I would always suggest that you bring in a urine sample for your SLE consultations. Lupus nephritis doesn't have to be specifically symptomatic and a urine dip result can highlight if your kidney is unhappy (blood, protein). Of course there are other tests but this is a simple one.
💜 #FactFriday: Lupus nephritis can lead to kidney failure, but better access to treatments is saving lives. Staying informed about the risks and complications of lupus is an important step toward protecting your health.
Learn more about lupus-related causes of death: https://buff.ly/3PXMmgd
Learn more about lupus-related causes of death: https://buff.ly/3PXMmgd
January 31, 2025 at 4:48 PM
I would always suggest that you bring in a urine sample for your SLE consultations. Lupus nephritis doesn't have to be specifically symptomatic and a urine dip result can highlight if your kidney is unhappy (blood, protein). Of course there are other tests but this is a simple one.
Good article. Thanks for sharing. Interesting to see a target for novel pain pathways. The difference with the sciatica pain also intriguing. Something to follow.
In a small piece of bright news: exciting news today for everyone who wishes there were a non-addictive, effective way to treat pain.
The first in a new class of medications was approved by the FDA 🛟🩺🧪
(Nb: The RCTs for approval focused on acute, not chronic, pain.)
www.nytimes.com/2025/01/30/h...
The first in a new class of medications was approved by the FDA 🛟🩺🧪
(Nb: The RCTs for approval focused on acute, not chronic, pain.)
www.nytimes.com/2025/01/30/h...
FDA Approves Journavx Drug to Treat Pain Without Addiction Risk
The drug, Journavx by Vertex Pharmaceuticals, blocks pain signals to the brain, making it nonaddictive.
www.nytimes.com
January 31, 2025 at 8:08 AM
Good article. Thanks for sharing. Interesting to see a target for novel pain pathways. The difference with the sciatica pain also intriguing. Something to follow.
I read once, that a sign of a civilised society was finding evidence of bone growth in someone with a broken thigh. Here's to new bone growth in our society.
whofoundation.donorsupport.co/page/FUNEKRB...
#1dollar1world
#HealthForAll whofoundation.donorsupport.co/page/FUNEKRB...
whofoundation.donorsupport.co/page/FUNEKRB...
#1dollar1world
#HealthForAll whofoundation.donorsupport.co/page/FUNEKRB...
1 Dollar, 1 World
I have been at WHO for over 10 years. Like my colleagues, I have worked my butt off day and night to fight Covid and work towards universal access to health care. This place frustrates me every day.
whofoundation.donorsupport.co
January 26, 2025 at 12:18 PM
I read once, that a sign of a civilised society was finding evidence of bone growth in someone with a broken thigh. Here's to new bone growth in our society.
whofoundation.donorsupport.co/page/FUNEKRB...
#1dollar1world
#HealthForAll whofoundation.donorsupport.co/page/FUNEKRB...
whofoundation.donorsupport.co/page/FUNEKRB...
#1dollar1world
#HealthForAll whofoundation.donorsupport.co/page/FUNEKRB...
Reposted by CMcG Rheum
🧪 Modern menopausal hormone therapy, using safer options like transdermal patches and bioidentical hormones, may lower risks of heart disease and osteoporosis if started within 10 years of menopause or before age 60. 🩺 🛟
The new science of menopause: these emerging therapies could change women’s health
Researchers are exploring how to prolong ovarian life and revisiting hormone replacement therapy — a once routine treatment that has fallen out of favour.
www.nature.com
January 22, 2025 at 4:57 PM
🧪 Modern menopausal hormone therapy, using safer options like transdermal patches and bioidentical hormones, may lower risks of heart disease and osteoporosis if started within 10 years of menopause or before age 60. 🩺 🛟
Reposted by CMcG Rheum
Attention #Medsky! We’re slowly rolling out the new .medsky.social handle.
Like the labeler this is another way to show your colleagues you’re a part of the Medsky network, and what’s great is you don’t have to be subscribed to the labeler for people to see it!
DM me to get your invite link!
Like the labeler this is another way to show your colleagues you’re a part of the Medsky network, and what’s great is you don’t have to be subscribed to the labeler for people to see it!
DM me to get your invite link!
January 18, 2025 at 3:17 PM
Attention #Medsky! We’re slowly rolling out the new .medsky.social handle.
Like the labeler this is another way to show your colleagues you’re a part of the Medsky network, and what’s great is you don’t have to be subscribed to the labeler for people to see it!
DM me to get your invite link!
Like the labeler this is another way to show your colleagues you’re a part of the Medsky network, and what’s great is you don’t have to be subscribed to the labeler for people to see it!
DM me to get your invite link!
Reposted by CMcG Rheum
Thanks @richard.medsky.social for organizing & adding me to the .medsky.social.handle!
DM Richard for an invite link to the labeler 👇
#medsky
DM Richard for an invite link to the labeler 👇
#medsky
Attention #Medsky! We’re slowly rolling out the new .medsky.social handle.
Like the labeler this is another way to show your colleagues you’re a part of the Medsky network, and what’s great is you don’t have to be subscribed to the labeler for people to see it!
DM me to get your invite link!
Like the labeler this is another way to show your colleagues you’re a part of the Medsky network, and what’s great is you don’t have to be subscribed to the labeler for people to see it!
DM me to get your invite link!
January 19, 2025 at 9:55 PM
Thanks @richard.medsky.social for organizing & adding me to the .medsky.social.handle!
DM Richard for an invite link to the labeler 👇
#medsky
DM Richard for an invite link to the labeler 👇
#medsky
Reposted by CMcG Rheum
“...electrical stimulation of the vagus nerve—a major nerve connecting the brain and gut—may combat the #stress-related #inflammation that worsens #IBD symptoms.” bit.ly/3OjM8iG bit.ly/3YZYqBW
Vagal stimulation ameliorates murine colitis by regulating SUMOylation
Vagal stimulation or inhibition of SUMOylation with TAK-981 ameliorates colitis in mouse models.
bit.ly
November 22, 2024 at 8:56 PM
“...electrical stimulation of the vagus nerve—a major nerve connecting the brain and gut—may combat the #stress-related #inflammation that worsens #IBD symptoms.” bit.ly/3OjM8iG bit.ly/3YZYqBW