McVey lab
@mcveylab.bsky.social
A group of hard-working, hard-playing researchers investigating genome stability in fruit flies and beyond. We advocate for interdisciplinary science, innovative pedagogy, and effective mentoring.
Reposted by McVey lab
Join us in our plenary #seminar this week, with @crisprflydesign.bsky.social, from @dkfz.bsky.social.
Host: Dr. @milanlab.bsky.social
Register here ➡️ https://shorturl.at/gBv1J
#Drosophila #DrosophilaResearch #CRISPR
🧪
Host: Dr. @milanlab.bsky.social
Register here ➡️ https://shorturl.at/gBv1J
#Drosophila #DrosophilaResearch #CRISPR
🧪
October 13, 2025 at 9:02 AM
Join us in our plenary #seminar this week, with @crisprflydesign.bsky.social, from @dkfz.bsky.social.
Host: Dr. @milanlab.bsky.social
Register here ➡️ https://shorturl.at/gBv1J
#Drosophila #DrosophilaResearch #CRISPR
🧪
Host: Dr. @milanlab.bsky.social
Register here ➡️ https://shorturl.at/gBv1J
#Drosophila #DrosophilaResearch #CRISPR
🧪
Reposted by McVey lab
A comprehensive genetic catalog of human double-strand break repair | Science www.science.org/doi/10.1126/...
A comprehensive genetic catalog of human double-strand break repair
The analysis of DNA sequence outcomes provides molecular insights into double-strand break (DSB) repair mechanisms. Using parallel in-pool profiling of Cas9-induced insertions and deletions (indels) w...
www.science.org
October 2, 2025 at 6:47 PM
A comprehensive genetic catalog of human double-strand break repair | Science www.science.org/doi/10.1126/...
This made my day. Gotta watch those hot mikes.
😭😭😭
Referee: "Holding, offense, number 64"
Number 64: "FUCK!"
Number 64: "FUCK!"
September 7, 2025 at 5:17 PM
This made my day. Gotta watch those hot mikes.
Reposted by McVey lab
Every few months the "good lab hands" thing comes up and it misses a key point: you can learn to have good hands. Training matters.
Good hands aren't some magic gift from the PCR gods, you have to develop them through directed repetitive practice, like any other skill
Good hands aren't some magic gift from the PCR gods, you have to develop them through directed repetitive practice, like any other skill
September 1, 2025 at 6:04 PM
Every few months the "good lab hands" thing comes up and it misses a key point: you can learn to have good hands. Training matters.
Good hands aren't some magic gift from the PCR gods, you have to develop them through directed repetitive practice, like any other skill
Good hands aren't some magic gift from the PCR gods, you have to develop them through directed repetitive practice, like any other skill
Reposted by McVey lab
It is not always safe to repair DNA Damage. Sometimes, cells "just bypass it".
During DNA replication, repair of lesions on DNA can be dangerous. Cells instead "tolerate" DNA damage and focus on finishing replication.
Read our review and find out why and how: doi.org/10.1016/j.ti...
During DNA replication, repair of lesions on DNA can be dangerous. Cells instead "tolerate" DNA damage and focus on finishing replication.
Read our review and find out why and how: doi.org/10.1016/j.ti...
August 22, 2025 at 11:48 AM
It is not always safe to repair DNA Damage. Sometimes, cells "just bypass it".
During DNA replication, repair of lesions on DNA can be dangerous. Cells instead "tolerate" DNA damage and focus on finishing replication.
Read our review and find out why and how: doi.org/10.1016/j.ti...
During DNA replication, repair of lesions on DNA can be dangerous. Cells instead "tolerate" DNA damage and focus on finishing replication.
Read our review and find out why and how: doi.org/10.1016/j.ti...
Reposted by McVey lab
We have openings for a postdoctoral training program on DNA Damage and Oncogenic Signaling. Our past trainees have been very successful. Apply by Aug 31 for full consideration. See link for details. www.imgs-coh.edu/postdoctoral...
Postdoctoral Training Programs
Funded by the National Cancer Institute (T32CA186895), the program at City of Hope provides exceptionally motivated, recent (2 years or less) postdoctoral fellows with scientific knowledge, researc
www.imgs-coh.edu
August 19, 2025 at 6:32 PM
We have openings for a postdoctoral training program on DNA Damage and Oncogenic Signaling. Our past trainees have been very successful. Apply by Aug 31 for full consideration. See link for details. www.imgs-coh.edu/postdoctoral...
Reposted by McVey lab
Reposted by McVey lab
Reposted by McVey lab
Scientists!
@skypeascientist.bsky.social matches scientists with classrooms, libraries, & more for virtual Q&As! It's easy and fun!
We are looking for 750 more volunteers by 8/15
If you're down to chat with 1-5 classrooms this semester, sign up here
www.skypeascientist.com/sign-up.html
@skypeascientist.bsky.social matches scientists with classrooms, libraries, & more for virtual Q&As! It's easy and fun!
We are looking for 750 more volunteers by 8/15
If you're down to chat with 1-5 classrooms this semester, sign up here
www.skypeascientist.com/sign-up.html
August 7, 2025 at 3:10 PM
Scientists!
@skypeascientist.bsky.social matches scientists with classrooms, libraries, & more for virtual Q&As! It's easy and fun!
We are looking for 750 more volunteers by 8/15
If you're down to chat with 1-5 classrooms this semester, sign up here
www.skypeascientist.com/sign-up.html
@skypeascientist.bsky.social matches scientists with classrooms, libraries, & more for virtual Q&As! It's easy and fun!
We are looking for 750 more volunteers by 8/15
If you're down to chat with 1-5 classrooms this semester, sign up here
www.skypeascientist.com/sign-up.html
If there is any way that the scientific community can prevent this, we MUST try!
I just got the notice that all the FlyBase people at Harvard, including me, will be laid off on October 12. I'm devastated.
August 11, 2025 at 11:08 PM
If there is any way that the scientific community can prevent this, we MUST try!
Reposted by McVey lab
Important new document available regarding SCOTUS and NIH grants.
scienceandfreedomalliance.substack.com/p/tell-the-s...
1/2
scienceandfreedomalliance.substack.com/p/tell-the-s...
1/2
Tell the Supreme Court: No Stay. Hands off NIH
The Supreme Court is poised to allow Trump to illegally terminate NIH grants. Let's speak out. There is not much time.
scienceandfreedomalliance.substack.com
August 7, 2025 at 8:51 PM
Important new document available regarding SCOTUS and NIH grants.
scienceandfreedomalliance.substack.com/p/tell-the-s...
1/2
scienceandfreedomalliance.substack.com/p/tell-the-s...
1/2
Reposted by McVey lab
Proud of FASEB, ASM, ASCB, and ASBMB.
August 4, 2025 at 11:44 PM
Proud of FASEB, ASM, ASCB, and ASBMB.
Reposted by McVey lab
Check out this new review (with animations, natch) of mechanisms of licensing origins of DNA replication - a wonderful (and continuing!) collaboration with Bruce Stillman @cshlnews.bsky.social and John Diffley @crick.ac.uk! www.nature.com/articles/s41...
July 2, 2025 at 5:01 PM
Check out this new review (with animations, natch) of mechanisms of licensing origins of DNA replication - a wonderful (and continuing!) collaboration with Bruce Stillman @cshlnews.bsky.social and John Diffley @crick.ac.uk! www.nature.com/articles/s41...
Reposted by McVey lab
An important correction in the NYT, to a chart that was shared a lot in recent days & that I shared myself, shows they'd made a mistake with the 18-24 year old turnout, and so it's not the case that age group outvoted all others.
Still: nothing to sneeze at here, still a huge surge in youth vote.
Still: nothing to sneeze at here, still a huge surge in youth vote.
July 1, 2025 at 12:07 AM
An important correction in the NYT, to a chart that was shared a lot in recent days & that I shared myself, shows they'd made a mistake with the 18-24 year old turnout, and so it's not the case that age group outvoted all others.
Still: nothing to sneeze at here, still a huge surge in youth vote.
Still: nothing to sneeze at here, still a huge surge in youth vote.
I think that this is one of the most difficult aspects of science today—finding time to think and reflect.
If you don’t have time to take a walk, then you don’t have time to do science. Charles Darwin would take two walks every day on his "thinking path", not as a break from science, but as a crucial part of it.
July 1, 2025 at 10:22 AM
I think that this is one of the most difficult aspects of science today—finding time to think and reflect.
It's unconscionable that Congress is rushing to pass the reconciliation bill, which polling indicates is wildly unpopular across citizens of both parties. This isn't a political football to get across the goal line. It's a morally bankrupt contract. There's no shame in taking extra time to fix it.
June 30, 2025 at 1:25 PM
It's unconscionable that Congress is rushing to pass the reconciliation bill, which polling indicates is wildly unpopular across citizens of both parties. This isn't a political football to get across the goal line. It's a morally bankrupt contract. There's no shame in taking extra time to fix it.
Yes! We need to replicate this graph across the country.
June 29, 2025 at 9:03 PM
Yes! We need to replicate this graph across the country.
Reposted by McVey lab
Although 500 new NSF GRFPs were added in June, the total number of fellowships in 2025 remains ~500 fewer than in 2024. Some fields—like CS and Physics—still saw net increases in total awards.
But others, including Life Sciences & Psychology, have taken hits of 50% or more compared to last year.
But others, including Life Sciences & Psychology, have taken hits of 50% or more compared to last year.
June 26, 2025 at 4:32 PM
Although 500 new NSF GRFPs were added in June, the total number of fellowships in 2025 remains ~500 fewer than in 2024. Some fields—like CS and Physics—still saw net increases in total awards.
But others, including Life Sciences & Psychology, have taken hits of 50% or more compared to last year.
But others, including Life Sciences & Psychology, have taken hits of 50% or more compared to last year.
Reposted by McVey lab
Too poor to science: how wealth determines who succeeds in STEM
Thought-provoking read, especially in these times of questioning diversity, equity and inclusion initiatives
🧪
Thought-provoking read, especially in these times of questioning diversity, equity and inclusion initiatives
🧪
From student to researcher, a #career in #science can come with a high price tag. @drcraigmc.bsky.social explores how wealth shapes opportunity in #STEM and proposes structural changes to support #equity and inclusion. 🧪
plos.io/4edGlY4
plos.io/4edGlY4
Too poor to science: How wealth determines who succeeds in STEM
From student to researcher, a career in science can come with a high price tag. This Perspective explores how persistent financial barriers limit who can succeed in science, revealing how wealth shape...
plos.io
June 27, 2025 at 9:31 AM
Too poor to science: how wealth determines who succeeds in STEM
Thought-provoking read, especially in these times of questioning diversity, equity and inclusion initiatives
🧪
Thought-provoking read, especially in these times of questioning diversity, equity and inclusion initiatives
🧪
This semester, the Tufts undergraduate Biology of Aging class created a new set of YouTube Videos describing the science behind different healthspan-promoting interventions. There were some really creative and informative entries! Check them out here: www.youtube.com/@BiologyofAg...
Biology of Aging at Tufts
www.youtube.com
May 30, 2025 at 2:47 PM
This semester, the Tufts undergraduate Biology of Aging class created a new set of YouTube Videos describing the science behind different healthspan-promoting interventions. There were some really creative and informative entries! Check them out here: www.youtube.com/@BiologyofAg...
Our department can say with conviction that people like Chiara are exactly the individuals whose careers we need to be supporting. Now is not the time to be pulling back from commitments to young scientists!
My friend and fellow Swiftie @chiaramasnovophd.bsky.social's story:
"Molecular biologist Chiara Masnovo spent weeks filling out an application for a research fellowship earlier this year — taking it over the finish line as she was 38 weeks pregnant and starting a new job."
"Molecular biologist Chiara Masnovo spent weeks filling out an application for a research fellowship earlier this year — taking it over the finish line as she was 38 weeks pregnant and starting a new job."
More bad news for early career scientists. By @aniloza.bsky.social www.statnews.com/2025/05/19/h...
May 20, 2025 at 1:28 PM
Our department can say with conviction that people like Chiara are exactly the individuals whose careers we need to be supporting. Now is not the time to be pulling back from commitments to young scientists!
Reposted by McVey lab
🧵5 Top Free Alternatives to BioRender for Scientific Illustrations!
These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.
Save and share the post!
These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.
Save and share the post!
May 13, 2025 at 7:55 PM
🧵5 Top Free Alternatives to BioRender for Scientific Illustrations!
These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.
Save and share the post!
These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.
Save and share the post!
Reposted by McVey lab
For those of you who rely on government websites for your research, American University has put together this guide to sites that have archived them.
subjectguides.library.american.edu/data_rescue/...
subjectguides.library.american.edu/data_rescue/...
Subject Guides: Government Information Data Rescue: Archives of Government Websites
Links to trusted repositories that have rescued U.S. government data
subjectguides.library.american.edu
May 9, 2025 at 2:30 PM
For those of you who rely on government websites for your research, American University has put together this guide to sites that have archived them.
subjectguides.library.american.edu/data_rescue/...
subjectguides.library.american.edu/data_rescue/...
This is good news. May the rule of law prevail.
BREAKING: Second Circuit panel, one day after arguments, unanimously rejects government's arguments and orders that Rumeysa Ozturk be transferred to Vermont no later than May 14. ww3.ca2.uscourts.gov/decisions/is...
May 7, 2025 at 4:58 PM
This is good news. May the rule of law prevail.