Maud Borensztein
@maudborensztein.bsky.social
Group Leader @igmm-montpel.bsky.social 👩🔬
Passionate about Development, Epigenetics and Reprogramming 🐭🧬🔬
X-chromosome inactivation aficionado!
https://www.igmm.cnrs.fr/en/team/epigenetic-reprogramming-and-mammalian-development/
Passionate about Development, Epigenetics and Reprogramming 🐭🧬🔬
X-chromosome inactivation aficionado!
https://www.igmm.cnrs.fr/en/team/epigenetic-reprogramming-and-mammalian-development/
Pinned
I am thrilled to share our latest work, released today 🤩
www-nature-com.insb.bib.cnrs.fr/articles/s41...
It results from years of hard work by the team and long-time collaborators, with special thanks to PhD student Clara Roidor and collaborator Laurène Syx.
www-nature-com.insb.bib.cnrs.fr/articles/s41...
It results from years of hard work by the team and long-time collaborators, with special thanks to PhD student Clara Roidor and collaborator Laurène Syx.
We are thrilled to host Elphège Nora next week in Montpellier 🤩 ☀️🧬
@elphegenoralab.bsky.social
@cnrsbiologie.bsky.social @biolum-montpellier.bsky.social @umontpellier.bsky.social
#transcription
@elphegenoralab.bsky.social
@cnrsbiologie.bsky.social @biolum-montpellier.bsky.social @umontpellier.bsky.social
#transcription
Save the date : Seminar Dr Elphège Nora from UCSF on Tuesday 18 November at 11am @elphegenoralab.bsky.social
November 12, 2025 at 8:37 AM
We are thrilled to host Elphège Nora next week in Montpellier 🤩 ☀️🧬
@elphegenoralab.bsky.social
@cnrsbiologie.bsky.social @biolum-montpellier.bsky.social @umontpellier.bsky.social
#transcription
@elphegenoralab.bsky.social
@cnrsbiologie.bsky.social @biolum-montpellier.bsky.social @umontpellier.bsky.social
#transcription
Reposted by Maud Borensztein
🧬Le magazine de la Métropole de Montpellier consacre un article à Jamal Tazi, pour son rôle dans la découverte de l’Obefazimod (ABX464), molécule issue de la recherche académique et développée grâce à une collaboration public-privé exemplaire.
encommun.montpellier.fr/sites/defaul...
encommun.montpellier.fr/sites/defaul...
encommun.montpellier.fr
November 7, 2025 at 12:32 PM
🧬Le magazine de la Métropole de Montpellier consacre un article à Jamal Tazi, pour son rôle dans la découverte de l’Obefazimod (ABX464), molécule issue de la recherche académique et développée grâce à une collaboration public-privé exemplaire.
encommun.montpellier.fr/sites/defaul...
encommun.montpellier.fr/sites/defaul...
Reposted by Maud Borensztein
New paper from the lab: we’re using long-read sequencing to disentangle isoform complexity at allele-specific loci 🧬💡
Here, we combine the PacBio Iso-Seq workflow with the established WhatsHap phasing approach to assign long reads to the correct allele in polymorphic F1 mouse hybrids.
Here, we combine the PacBio Iso-Seq workflow with the established WhatsHap phasing approach to assign long reads to the correct allele in polymorphic F1 mouse hybrids.
November 11, 2025 at 7:00 PM
New paper from the lab: we’re using long-read sequencing to disentangle isoform complexity at allele-specific loci 🧬💡
Here, we combine the PacBio Iso-Seq workflow with the established WhatsHap phasing approach to assign long reads to the correct allele in polymorphic F1 mouse hybrids.
Here, we combine the PacBio Iso-Seq workflow with the established WhatsHap phasing approach to assign long reads to the correct allele in polymorphic F1 mouse hybrids.
Reposted by Maud Borensztein
Spread the word! There is a professor position opening at our University @upcite.bsky.social. There are several possible (great) labs to join, but if you are interested in DNA methylation and epigenetics in mammals, don't hesitate to contact me directly!
#JobOffer
💼 Un poste susceptible d’être vacant de Professeur en stabilité des génomes devrait s’ouvrir pour la rentrée 2026 au sein de l’Institut Jacques Monod
➡️ Informations concernant ce poste et la procédure de candidature 🔗 www.ijm.fr/poste-de-pro...
💼 Un poste susceptible d’être vacant de Professeur en stabilité des génomes devrait s’ouvrir pour la rentrée 2026 au sein de l’Institut Jacques Monod
➡️ Informations concernant ce poste et la procédure de candidature 🔗 www.ijm.fr/poste-de-pro...
October 28, 2025 at 1:51 PM
Spread the word! There is a professor position opening at our University @upcite.bsky.social. There are several possible (great) labs to join, but if you are interested in DNA methylation and epigenetics in mammals, don't hesitate to contact me directly!
Reposted by Maud Borensztein
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
October 15, 2025 at 12:22 PM
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
Reposted by Maud Borensztein
@viroscope.bsky.social (@karimaj.bsky.social team) partage dans The Scientist ses travaux sur les deltavirus et l’imagerie de cellules, des cellules humaines aux cellules de boa constrictor 🐍.
👉 Lire l’article : “Boa Constrictor Brain Cells Slither into Focus”
www.the-scientist.com/boa-constric...
👉 Lire l’article : “Boa Constrictor Brain Cells Slither into Focus”
www.the-scientist.com/boa-constric...
Boa Constrictor Brain Cells Slither into Focus
From reptiles and Tasmanian devils to humans, one researcher zooms in on unseen features of the brain and liver cells, like the cytoskeleton.
www.the-scientist.com
October 13, 2025 at 11:13 AM
@viroscope.bsky.social (@karimaj.bsky.social team) partage dans The Scientist ses travaux sur les deltavirus et l’imagerie de cellules, des cellules humaines aux cellules de boa constrictor 🐍.
👉 Lire l’article : “Boa Constrictor Brain Cells Slither into Focus”
www.the-scientist.com/boa-constric...
👉 Lire l’article : “Boa Constrictor Brain Cells Slither into Focus”
www.the-scientist.com/boa-constric...
Reposted by Maud Borensztein
The Crick is looking for new junior group leaders! Any postdocs or early career researchers wanting to be our colleagues should apply 👍
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
October 9, 2025 at 4:49 PM
The Crick is looking for new junior group leaders! Any postdocs or early career researchers wanting to be our colleagues should apply 👍
Reposted by Maud Borensztein
An Interview with Azim Surani
Ashley Moffett and @geraldinejowett.bsky.social spoke to Azim, recipient of both the 2025 Kyoto Prize and 2026 Paul Ehrlich and Ludwig Darmstaedter Prize, about his non-traditional and inspirational route into academia:
journals.biologists.com/dev/article/...
Ashley Moffett and @geraldinejowett.bsky.social spoke to Azim, recipient of both the 2025 Kyoto Prize and 2026 Paul Ehrlich and Ludwig Darmstaedter Prize, about his non-traditional and inspirational route into academia:
journals.biologists.com/dev/article/...
October 9, 2025 at 5:05 PM
An Interview with Azim Surani
Ashley Moffett and @geraldinejowett.bsky.social spoke to Azim, recipient of both the 2025 Kyoto Prize and 2026 Paul Ehrlich and Ludwig Darmstaedter Prize, about his non-traditional and inspirational route into academia:
journals.biologists.com/dev/article/...
Ashley Moffett and @geraldinejowett.bsky.social spoke to Azim, recipient of both the 2025 Kyoto Prize and 2026 Paul Ehrlich and Ludwig Darmstaedter Prize, about his non-traditional and inspirational route into academia:
journals.biologists.com/dev/article/...
Reposted by Maud Borensztein
⚠️ Paper alert: Using a novel CRISPR screening approach, we mapped the entire regulatory network controlling Xist—key for X-chromosome inactivation.
👉 We discover how sex and development signals are decoded at a single gene locus.
www.nature.com/articles/s41...
👇 Bluetorial
👉 We discover how sex and development signals are decoded at a single gene locus.
www.nature.com/articles/s41...
👇 Bluetorial
Reporter CRISPR screens decipher cis-regulatory and trans-regulatory principles at the Xist locus - Nature Structural & Molecular Biology
Here Schwämmle et al. develop CRISPR reporter screens to map transcription-factor-regulatory element interactions at the Xist locus, revealing a two-step mechanism integrating developmental and X-dosage signals to initiate X-chromosome inactivation.
www.nature.com
October 6, 2025 at 1:02 PM
⚠️ Paper alert: Using a novel CRISPR screening approach, we mapped the entire regulatory network controlling Xist—key for X-chromosome inactivation.
👉 We discover how sex and development signals are decoded at a single gene locus.
www.nature.com/articles/s41...
👇 Bluetorial
👉 We discover how sex and development signals are decoded at a single gene locus.
www.nature.com/articles/s41...
👇 Bluetorial
Reposted by Maud Borensztein
Is anyone in continental Europe looking for a lab manager? I have a fabulous candidate - let me know and please RT!
August 25, 2025 at 8:03 PM
Is anyone in continental Europe looking for a lab manager? I have a fabulous candidate - let me know and please RT!
Reposted by Maud Borensztein
DNA methylation at #retrotransposons protects the #germline by preventing NRF1-mediated #activation.
-> www.embopress.org/doi/full/10....
-> www.embopress.org/doi/full/10....
August 7, 2025 at 10:54 AM
DNA methylation at #retrotransposons protects the #germline by preventing NRF1-mediated #activation.
-> www.embopress.org/doi/full/10....
-> www.embopress.org/doi/full/10....
Reposted by Maud Borensztein
#jobAlert We are hiring! If you like #imaging ,gene regulation and a dynamic group please apply. We are looking for a research assistant with a master degree and prior experience in academia.
🎯 Hiring: Biology Research Assistant (M/F)
Join IGMM Montpellier to study gene expression dynamics during Drosophila development @laghalab.bsky.social
6-month contract, renewable up to 2 years.
Start Sept 15, 2025 | Apply by Aug 11
🔗 emploi.cnrs.fr/Offres/CDD/U...
#Hiring #Biology #Research #IGMM
Join IGMM Montpellier to study gene expression dynamics during Drosophila development @laghalab.bsky.social
6-month contract, renewable up to 2 years.
Start Sept 15, 2025 | Apply by Aug 11
🔗 emploi.cnrs.fr/Offres/CDD/U...
#Hiring #Biology #Research #IGMM
Portail Emploi CNRS - Offre d'emploi - Assistant ingénieur en biologie (H/F)
emploi.cnrs.fr
July 28, 2025 at 4:11 PM
Reposted by Maud Borensztein
🚀 @hfspo.bsky.social funded Postdoc
3-year contract
Start after Dec 2025
📩 Apply: mounia.lagha@igmm.cnrs.fr
Subject: "[HFSP Post doc application]"
📎 CV + short research summary + cover letter
🔗 More info: euraxess.ec.europa.eu/jobs/363437
@laghalab.bsky.social @umontpellier.bsky.social @cnrs.fr
3-year contract
Start after Dec 2025
📩 Apply: mounia.lagha@igmm.cnrs.fr
Subject: "[HFSP Post doc application]"
📎 CV + short research summary + cover letter
🔗 More info: euraxess.ec.europa.eu/jobs/363437
@laghalab.bsky.social @umontpellier.bsky.social @cnrs.fr
A PhD in biology, biophysics or a closely related field is required by the start of the appointment. Interdisciplinary profiles are strongly encouraged to apply.
- work environment:
euraxess.ec.europa.eu
July 28, 2025 at 8:18 AM
🚀 @hfspo.bsky.social funded Postdoc
3-year contract
Start after Dec 2025
📩 Apply: mounia.lagha@igmm.cnrs.fr
Subject: "[HFSP Post doc application]"
📎 CV + short research summary + cover letter
🔗 More info: euraxess.ec.europa.eu/jobs/363437
@laghalab.bsky.social @umontpellier.bsky.social @cnrs.fr
3-year contract
Start after Dec 2025
📩 Apply: mounia.lagha@igmm.cnrs.fr
Subject: "[HFSP Post doc application]"
📎 CV + short research summary + cover letter
🔗 More info: euraxess.ec.europa.eu/jobs/363437
@laghalab.bsky.social @umontpellier.bsky.social @cnrs.fr
Reposted by Maud Borensztein
🎯 Hiring: Biology Research Assistant (M/F)
Join IGMM Montpellier to study gene expression dynamics during Drosophila development @laghalab.bsky.social
6-month contract, renewable up to 2 years.
Start Sept 15, 2025 | Apply by Aug 11
🔗 emploi.cnrs.fr/Offres/CDD/U...
#Hiring #Biology #Research #IGMM
Join IGMM Montpellier to study gene expression dynamics during Drosophila development @laghalab.bsky.social
6-month contract, renewable up to 2 years.
Start Sept 15, 2025 | Apply by Aug 11
🔗 emploi.cnrs.fr/Offres/CDD/U...
#Hiring #Biology #Research #IGMM
Portail Emploi CNRS - Offre d'emploi - Assistant ingénieur en biologie (H/F)
emploi.cnrs.fr
July 28, 2025 at 7:47 AM
🎯 Hiring: Biology Research Assistant (M/F)
Join IGMM Montpellier to study gene expression dynamics during Drosophila development @laghalab.bsky.social
6-month contract, renewable up to 2 years.
Start Sept 15, 2025 | Apply by Aug 11
🔗 emploi.cnrs.fr/Offres/CDD/U...
#Hiring #Biology #Research #IGMM
Join IGMM Montpellier to study gene expression dynamics during Drosophila development @laghalab.bsky.social
6-month contract, renewable up to 2 years.
Start Sept 15, 2025 | Apply by Aug 11
🔗 emploi.cnrs.fr/Offres/CDD/U...
#Hiring #Biology #Research #IGMM
Reposted by Maud Borensztein
🧬 Avancée majeure issue d’Abivax et de l’équipe Tazi @igmm-montpel.bsky.social @cnrs.fr @umontpellier.bsky.social @cnrsbiologie.bsky.social
Le 23 juillet 2027, Abivax annonce des résultats très positifs en phase 3 pour obefazimod contre la RCH.
📈 +520 % en bourse @lemonde.fr
Le 23 juillet 2027, Abivax annonce des résultats très positifs en phase 3 pour obefazimod contre la RCH.
📈 +520 % en bourse @lemonde.fr
July 25, 2025 at 8:49 AM
🧬 Avancée majeure issue d’Abivax et de l’équipe Tazi @igmm-montpel.bsky.social @cnrs.fr @umontpellier.bsky.social @cnrsbiologie.bsky.social
Le 23 juillet 2027, Abivax annonce des résultats très positifs en phase 3 pour obefazimod contre la RCH.
📈 +520 % en bourse @lemonde.fr
Le 23 juillet 2027, Abivax annonce des résultats très positifs en phase 3 pour obefazimod contre la RCH.
📈 +520 % en bourse @lemonde.fr
Reposted by Maud Borensztein
Fantastique !!!
🧬 Avancée majeure issue d’Abivax et de l’équipe Tazi @igmm-montpel.bsky.social @cnrs.fr @umontpellier.bsky.social @cnrsbiologie.bsky.social
Le 23 juillet 2027, Abivax annonce des résultats très positifs en phase 3 pour obefazimod contre la RCH.
📈 +520 % en bourse @lemonde.fr
Le 23 juillet 2027, Abivax annonce des résultats très positifs en phase 3 pour obefazimod contre la RCH.
📈 +520 % en bourse @lemonde.fr
July 25, 2025 at 2:34 PM
Fantastique !!!
Reposted by Maud Borensztein
Two major events today on our campus!
🚴♀️First, the Tour de France is passing right next to us — @cnrsoccitanieest.bsky.social!
🧬Second, our latest paper on the role of G-quadruplexes (G4s) at promoters is now online at @natgenet.nature.com!
🚴♀️First, the Tour de France is passing right next to us — @cnrsoccitanieest.bsky.social!
🧬Second, our latest paper on the role of G-quadruplexes (G4s) at promoters is now online at @natgenet.nature.com!
July 22, 2025 at 12:25 PM
Two major events today on our campus!
🚴♀️First, the Tour de France is passing right next to us — @cnrsoccitanieest.bsky.social!
🧬Second, our latest paper on the role of G-quadruplexes (G4s) at promoters is now online at @natgenet.nature.com!
🚴♀️First, the Tour de France is passing right next to us — @cnrsoccitanieest.bsky.social!
🧬Second, our latest paper on the role of G-quadruplexes (G4s) at promoters is now online at @natgenet.nature.com!
Reposted by Maud Borensztein
60 days to go for applying to marie-sklodowska-curie-actions.ec.europa.eu/actions/post... if you want to join me to study ageing with an interesting new angle!
#Smurfs #2PAC
#Smurfs #2PAC
Postdoctoral Fellowships
The information provided on this page is a summary of the main rules and requirements for Postdoctoral Fellowships (PFs) and who can apply for them.
marie-sklodowska-curie-actions.ec.europa.eu
July 23, 2025 at 9:20 AM
60 days to go for applying to marie-sklodowska-curie-actions.ec.europa.eu/actions/post... if you want to join me to study ageing with an interesting new angle!
#Smurfs #2PAC
#Smurfs #2PAC
Reposted by Maud Borensztein
We are looking for a student to continue our work on chromatin evolution:
www.nature.com/articles/s41...
www.biorxiv.org/content/10.1...
The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes.
More info: recruitment.crg.eu/content/jobs...
www.nature.com/articles/s41...
www.biorxiv.org/content/10.1...
The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes.
More info: recruitment.crg.eu/content/jobs...
July 15, 2025 at 11:30 AM
We are looking for a student to continue our work on chromatin evolution:
www.nature.com/articles/s41...
www.biorxiv.org/content/10.1...
The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes.
More info: recruitment.crg.eu/content/jobs...
www.nature.com/articles/s41...
www.biorxiv.org/content/10.1...
The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes.
More info: recruitment.crg.eu/content/jobs...
Reposted by Maud Borensztein
Congratulations to the Carnesecchi lab 🍾🍾
Read below to learn more about their research 👇
Read below to learn more about their research 👇
🎉 Thrilled to share our new paper in @narjournal.bsky.social!
We uncover how the Hox TF Ultrabithorax controls alternative splicing to shape muscle patterning and homeotic identity 🧬 @igmm-montpel.bsky.social
🔗 doi.org/10.1093/nar/...
We uncover how the Hox TF Ultrabithorax controls alternative splicing to shape muscle patterning and homeotic identity 🧬 @igmm-montpel.bsky.social
🔗 doi.org/10.1093/nar/...
Synergistic DNA and RNA binding of the Hox transcription factor Ultrabithorax coordinates splicing and shapes in vivo homeotic functions
Abstract. The dual interaction of many transcription factors (TFs) with both DNA and RNA is an underexplored issue that could fundamentally reshape our und
doi.org
July 7, 2025 at 8:39 AM
Congratulations to the Carnesecchi lab 🍾🍾
Read below to learn more about their research 👇
Read below to learn more about their research 👇
Reposted by Maud Borensztein
Join us in the #institutcurie exceptional environment to explore the mysteries of X chromosome regulation in early human development
If you are interested by epigenetics, early human development in excellent scientific environment in middle of Paris, we are recruiting a postdoc.
app.beetween.com/WeaselWeb/p/...
Don't hesitate to apply or share the post !
app.beetween.com/WeaselWeb/p/...
Don't hesitate to apply or share the post !
Beetween
app.beetween.com
June 18, 2025 at 9:44 AM
Join us in the #institutcurie exceptional environment to explore the mysteries of X chromosome regulation in early human development
Reposted by Maud Borensztein
Save the date : Seminar Elphège NORA - June 19h - 11am
@elphegenoralab.bsky.social
@elphegenoralab.bsky.social
June 6, 2025 at 2:27 PM
Save the date : Seminar Elphège NORA - June 19h - 11am
@elphegenoralab.bsky.social
@elphegenoralab.bsky.social
Reposted by Maud Borensztein
Planning to apply for #research #funding from the ERC?
From the next application rounds, expect changes to the:
• proposal structure
• evaluation process
• extra funding you can request
• eligibility for Starting & Consolidator #Grants (from 2027)
More 👇 europa.eu/!RPHWvv
From the next application rounds, expect changes to the:
• proposal structure
• evaluation process
• extra funding you can request
• eligibility for Starting & Consolidator #Grants (from 2027)
More 👇 europa.eu/!RPHWvv
Changes to the 2026 and 2027 Work Programmes
With the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai...
europa.eu
June 2, 2025 at 10:02 AM
Planning to apply for #research #funding from the ERC?
From the next application rounds, expect changes to the:
• proposal structure
• evaluation process
• extra funding you can request
• eligibility for Starting & Consolidator #Grants (from 2027)
More 👇 europa.eu/!RPHWvv
From the next application rounds, expect changes to the:
• proposal structure
• evaluation process
• extra funding you can request
• eligibility for Starting & Consolidator #Grants (from 2027)
More 👇 europa.eu/!RPHWvv
We are recruiting at @igmm-montpel.bsky.social
Join us in a dynamic scientific environment in beautiful and sunny Montpellier 👩🔬👨🔬☀️
For questions, feel free to write to search2025@igmm.cnrs.fr or DM me!
Join us in a dynamic scientific environment in beautiful and sunny Montpellier 👩🔬👨🔬☀️
For questions, feel free to write to search2025@igmm.cnrs.fr or DM me!
📣 We are recruiting new group leaders in Innovative Biology!
RNA biology
Epigenetic regulation
Cell cycle regulation
Cancer, immunology
Virology
Application and information ⬇️
application.igmm.cnrs.fr
@cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social
RNA biology
Epigenetic regulation
Cell cycle regulation
Cancer, immunology
Virology
Application and information ⬇️
application.igmm.cnrs.fr
@cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social
May 28, 2025 at 12:28 PM
We are recruiting at @igmm-montpel.bsky.social
Join us in a dynamic scientific environment in beautiful and sunny Montpellier 👩🔬👨🔬☀️
For questions, feel free to write to search2025@igmm.cnrs.fr or DM me!
Join us in a dynamic scientific environment in beautiful and sunny Montpellier 👩🔬👨🔬☀️
For questions, feel free to write to search2025@igmm.cnrs.fr or DM me!
Reposted by Maud Borensztein
📣 We are recruiting new group leaders in Innovative Biology!
RNA biology
Epigenetic regulation
Cell cycle regulation
Cancer, immunology
Virology
Application and information ⬇️
application.igmm.cnrs.fr
@cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social
RNA biology
Epigenetic regulation
Cell cycle regulation
Cancer, immunology
Virology
Application and information ⬇️
application.igmm.cnrs.fr
@cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social
May 28, 2025 at 12:12 PM
📣 We are recruiting new group leaders in Innovative Biology!
RNA biology
Epigenetic regulation
Cell cycle regulation
Cancer, immunology
Virology
Application and information ⬇️
application.igmm.cnrs.fr
@cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social
RNA biology
Epigenetic regulation
Cell cycle regulation
Cancer, immunology
Virology
Application and information ⬇️
application.igmm.cnrs.fr
@cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social