Dr. Krissy Lyon
@krissylyon.bsky.social
Neuroscientist & astrocyte enthusiast | Postdoc in the Allen lab @SalkInstitute.bsky.social | NINDS K99 |@lclark.bsky.social and Harvard PiN alum | she/her
Pinned
Dr. Krissy Lyon
@krissylyon.bsky.social
· Nov 12
Frontiers | From Synapses to Circuits, Astrocytes Regulate Behavior
Astrocytes are non-neuronal cells that regulate synapses, neuronal circuits, and behavior. Astrocytes ensheath neuronal synapses to form the tripartite synap...
www.frontiersin.org
Hi Blue Sky! A reintroduction: I am a neuroscientist interested in neuron-glia interactions, astrocytes, behavior, neurodevelopment, and neurodevelopmental disorders. Currently a postdoc in the Allen lab at Salk 👩🏽🔬🧠 Here’s a review I wrote a couple years ago: www.frontiersin.org/journals/neu...
If you will be at #SfN25 next week, please join us for a professional development workshop ‘Navigating your career roadmap in a changing landscape’ on Monday from 12-2. Led by THE Dr. Michelle Jones-London. Please share with your lab and anyone you think would benefit!
November 10, 2025 at 4:35 PM
If you will be at #SfN25 next week, please join us for a professional development workshop ‘Navigating your career roadmap in a changing landscape’ on Monday from 12-2. Led by THE Dr. Michelle Jones-London. Please share with your lab and anyone you think would benefit!
Reposted by Dr. Krissy Lyon
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
November 5, 2025 at 5:48 PM
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
Reposted by Dr. Krissy Lyon
If you are attending #SfN25, please join @amygleichman.bsky.social and I on Monday at 9PM for a casual social gathering to discuss all things non-neuronal!
Date: Monday, Nov 17th
Time: 9PM till close
Location: The Smoking Gun SD, 555 Market St.
All welcome, please free to spread the word!
Date: Monday, Nov 17th
Time: 9PM till close
Location: The Smoking Gun SD, 555 Market St.
All welcome, please free to spread the word!
October 29, 2025 at 2:57 PM
If you are attending #SfN25, please join @amygleichman.bsky.social and I on Monday at 9PM for a casual social gathering to discuss all things non-neuronal!
Date: Monday, Nov 17th
Time: 9PM till close
Location: The Smoking Gun SD, 555 Market St.
All welcome, please free to spread the word!
Date: Monday, Nov 17th
Time: 9PM till close
Location: The Smoking Gun SD, 555 Market St.
All welcome, please free to spread the word!
Reposted by Dr. Krissy Lyon
Edward Kravitz, a Harvard biochemist who proved GABA's inhibitory power, passed away last month. He will "be remembered for his humanity, for his social conscience and his desire to help those less fortunate than he,” says Ronald Harris-Warrick.
By @claudia-lopez.bsky.social
bit.ly/479Ggmo
By @claudia-lopez.bsky.social
bit.ly/479Ggmo
Remembering GABA pioneer Edward Kravitz
The biochemist, who died last month at age 92, was part of the first neurobiology department in the world and showed that gamma-aminobutyric acid is inhibitory.
bit.ly
October 24, 2025 at 1:41 PM
Edward Kravitz, a Harvard biochemist who proved GABA's inhibitory power, passed away last month. He will "be remembered for his humanity, for his social conscience and his desire to help those less fortunate than he,” says Ronald Harris-Warrick.
By @claudia-lopez.bsky.social
bit.ly/479Ggmo
By @claudia-lopez.bsky.social
bit.ly/479Ggmo
Reposted by Dr. Krissy Lyon
It is based on a word cloud from the titles of the 197 MOSAIC grantee projects. I had it made if I have testify in the grant delay trial but it was perfect for this occasion.
Who needs PowerPoint?
Who needs PowerPoint?
October 16, 2025 at 7:23 PM
It is based on a word cloud from the titles of the 197 MOSAIC grantee projects. I had it made if I have testify in the grant delay trial but it was perfect for this occasion.
Who needs PowerPoint?
Who needs PowerPoint?
Reposted by Dr. Krissy Lyon
Lab’s 1st preprint!
Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate.
@cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation.
He is on the job market!
Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate.
@cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation.
He is on the job market!
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
Induction of menstruation in mice reveals the regulation of menstrual shedding
During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...
www.biorxiv.org
October 10, 2025 at 1:26 PM
Lab’s 1st preprint!
Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate.
@cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation.
He is on the job market!
Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate.
@cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation.
He is on the job market!
Reposted by Dr. Krissy Lyon
A huge shoutout to all the dedicated grants management specialists at the NIH who are working around the clock to push grants out before the Sep 30 deadline. And also to the POs responding to frantic emails.
Not an easy job under the best of circumstances and right now it's the pits.
Thank you!
Not an easy job under the best of circumstances and right now it's the pits.
Thank you!
September 15, 2025 at 8:17 PM
A huge shoutout to all the dedicated grants management specialists at the NIH who are working around the clock to push grants out before the Sep 30 deadline. And also to the POs responding to frantic emails.
Not an easy job under the best of circumstances and right now it's the pits.
Thank you!
Not an easy job under the best of circumstances and right now it's the pits.
Thank you!
Required periodic Salk Institute photo☀️
August 23, 2025 at 10:43 PM
Required periodic Salk Institute photo☀️
Reposted by Dr. Krissy Lyon
Postdocs applying for K99s, particularly if it's your last opportunity: DO NOT forget to include a foreign justification document if you have any sort of foreign collaboration. Your application will be withdrawn if you don't have that.
August 22, 2025 at 11:09 PM
Postdocs applying for K99s, particularly if it's your last opportunity: DO NOT forget to include a foreign justification document if you have any sort of foreign collaboration. Your application will be withdrawn if you don't have that.
Reposted by Dr. Krissy Lyon
Excited to share an important new pre-print from the lab led by incredibly talented postdoc @maureenbiologies.bsky.social, a neurotoxicologist who came to the lab with an ambitious goal of understanding the consequences of toxicant exposure in human neurodevelopment. www.biorxiv.org/content/10.1...
August 21, 2025 at 8:10 PM
Excited to share an important new pre-print from the lab led by incredibly talented postdoc @maureenbiologies.bsky.social, a neurotoxicologist who came to the lab with an ambitious goal of understanding the consequences of toxicant exposure in human neurodevelopment. www.biorxiv.org/content/10.1...
Reposted by Dr. Krissy Lyon
Several people have suggested that I compile my emails to Bhattacharya and I am delighted to do so.
Announcing the first cut of "Fifty Shades of 'Jay'
jeremymberg.github.io/jeremyberg.g...
This contains just the first few exchanges. I will be adding more as time permits.
Announcing the first cut of "Fifty Shades of 'Jay'
jeremymberg.github.io/jeremyberg.g...
This contains just the first few exchanges. I will be adding more as time permits.
August 18, 2025 at 7:18 PM
Several people have suggested that I compile my emails to Bhattacharya and I am delighted to do so.
Announcing the first cut of "Fifty Shades of 'Jay'
jeremymberg.github.io/jeremyberg.g...
This contains just the first few exchanges. I will be adding more as time permits.
Announcing the first cut of "Fifty Shades of 'Jay'
jeremymberg.github.io/jeremyberg.g...
This contains just the first few exchanges. I will be adding more as time permits.
Reposted by Dr. Krissy Lyon
Over 20 years after Julius’s lab and mine cloned TRPM8, it is rewarding to see this science helping patients. The TRPM8 agonist Tryptyr treats dry eye by increasing tear production. A reminder that NIH-funded curiosity-driven research translates to medicines.
tryptyr.myalcon.com?gad_source=1...
tryptyr.myalcon.com?gad_source=1...
TRYPTYR (acoltremon ophthalmic solution) 0.003% eye drops | Alcon US
TRYPTYR is a prescription eye drop used for the treatment of the signs and symptoms of dry eye disease. See prescribing information, how to save, and more.
tryptyr.myalcon.com
August 13, 2025 at 9:17 PM
Over 20 years after Julius’s lab and mine cloned TRPM8, it is rewarding to see this science helping patients. The TRPM8 agonist Tryptyr treats dry eye by increasing tear production. A reminder that NIH-funded curiosity-driven research translates to medicines.
tryptyr.myalcon.com?gad_source=1...
tryptyr.myalcon.com?gad_source=1...
Reposted by Dr. Krissy Lyon
FlyBase, a Drosophila database, will lose a third of its team in early October because the Harvard grant that covered the employees’ salaries was canceled. Scientists warn that losing FlyBase could devastate fly research.
By @claudia-lopez.bsky.social
www.thetransmitter.org/community/ha...
By @claudia-lopez.bsky.social
www.thetransmitter.org/community/ha...
Harvard University lays off fly database team
The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.
www.thetransmitter.org
August 13, 2025 at 7:32 PM
FlyBase, a Drosophila database, will lose a third of its team in early October because the Harvard grant that covered the employees’ salaries was canceled. Scientists warn that losing FlyBase could devastate fly research.
By @claudia-lopez.bsky.social
www.thetransmitter.org/community/ha...
By @claudia-lopez.bsky.social
www.thetransmitter.org/community/ha...
Reposted by Dr. Krissy Lyon
Update on NIH funding through July (August 1 budget start dates)
Non-competitive renewal awards by month for fiscal year 2025
1/7
Non-competitive renewal awards by month for fiscal year 2025
1/7
August 13, 2025 at 5:56 PM
Update on NIH funding through July (August 1 budget start dates)
Non-competitive renewal awards by month for fiscal year 2025
1/7
Non-competitive renewal awards by month for fiscal year 2025
1/7
Excited to have received the NOA for my K99 Pathway to Independence award on astrocytes in neurodevelopmental disorders! I am so grateful for my PI Nicola Allen, and all my mentors, letter writers, and collaborators.
August 12, 2025 at 4:47 PM
Excited to have received the NOA for my K99 Pathway to Independence award on astrocytes in neurodevelopmental disorders! I am so grateful for my PI Nicola Allen, and all my mentors, letter writers, and collaborators.
Cool astrocyte paper!
Astrocyte specification in the mouse septum is shaped by both developmental origin and local signals - Nature Neuroscience
The relative contribution of intrinsic and extrinsic factors to astrocyte heterogeneity is unknown. Using heterotropic transplantation of septal astrocytes with distinct lineage origins, we show that ...
www.nature.com
July 29, 2025 at 4:40 PM
Cool astrocyte paper!
Reposted by Dr. Krissy Lyon
To identify fundamental neuroscientific principles that generalize across species, systems and circuits, neuroscientists must embrace an evolutionary perspective, argue Karl Farrow and @katjareinhard.bsky.social.
#neuroskyence
www.thetransmitter.org/systems-neur...
#neuroskyence
www.thetransmitter.org/systems-neur...
Systems and circuit neuroscience need an evolutionary perspective
To identify fundamental neuroscientific principles that generalize across species, neuroscientists must frame their research through an evolutionary lens.
www.thetransmitter.org
July 16, 2025 at 2:02 PM
To identify fundamental neuroscientific principles that generalize across species, systems and circuits, neuroscientists must embrace an evolutionary perspective, argue Karl Farrow and @katjareinhard.bsky.social.
#neuroskyence
www.thetransmitter.org/systems-neur...
#neuroskyence
www.thetransmitter.org/systems-neur...
Reposted by Dr. Krissy Lyon
don't be fooled that this NIH effort is only about NOFO - listen to minute 21-22 "they are working tirelessly" to "phase out" "existing" funding www.youtube.com/watch?v=iSvk...
July 11, 2025 at 8:03 PM
don't be fooled that this NIH effort is only about NOFO - listen to minute 21-22 "they are working tirelessly" to "phase out" "existing" funding www.youtube.com/watch?v=iSvk...
Congratulations to all the new awardees!! Happy to see this program ongoing!
BWF is proud to announce the 2025 recipients of its Postdoctoral Diversity Enrichment Program (PDEP), which provides critical support to postdoctoral researchers pursuing careers in biomedical and medical research. www.bwfund.org/news/bwf-ann... #bwfpdep
BWF Announces 2025 Postdoctoral Diversity Enrichment Program Recipients - Burroughs Wellcome Fund
Research Triangle Park, N.C. — The Burroughs Wellcome Fund (BWF) is proud to announce the 2025 recipients of its Postdoctoral Diversity Enrichment Program (PDEP), which provides critical support to…
www.bwfund.org
July 10, 2025 at 7:55 PM
Congratulations to all the new awardees!! Happy to see this program ongoing!
Reposted by Dr. Krissy Lyon
In this entire 4.5 hour video from the FDA and NIH about reducing animal models, I didn't hear any discussion about conducting research developing new treatments for mental health disorders with behavioral symptoms
At 2:38:55 of this video is when the NIH component of the workshop begins. 2:49:11 is where the announcement of no new NIH funding of proposals relying exclusively on animals youtube.com/live/vz1uF42...
July 8, 2025 at 8:21 PM
In this entire 4.5 hour video from the FDA and NIH about reducing animal models, I didn't hear any discussion about conducting research developing new treatments for mental health disorders with behavioral symptoms
Reposted by Dr. Krissy Lyon
I'll be presenting at this science fair: I've done many a poster presentation, but never one quite like this!
A science fair of cancelled grants. The research that will be represented at this event (Tuesday) ranges from neuroscience, to astrophysics, to STEM education. The awarding agencies of the now-canceled grants include the EPA, DHS, NIH, NSF, USAID, and DOD. Open to the public.
Congressional Event: A Science Fair of Canceled Grants
The Things We’ll Never Know: A Science Fair of Canceled Grants.
nasawatch.com
July 7, 2025 at 2:46 PM
I'll be presenting at this science fair: I've done many a poster presentation, but never one quite like this!
Reposted by Dr. Krissy Lyon
BREAKING: Scientists are staging a “science fair” in the lobby of a Congressional building to tell elected officials about the critical knowledge the US will lose because their research grants have been canceled.
July 8, 2025 at 3:31 PM
BREAKING: Scientists are staging a “science fair” in the lobby of a Congressional building to tell elected officials about the critical knowledge the US will lose because their research grants have been canceled.
Reposted by Dr. Krissy Lyon
It would be great if other journals did this
Call for Submissions! Behavioral Medicine: Special Issue on Terminated Grants.
Submit by June 30 at 5PM ET. Learn more here: acrobat.adobe.com/id/urn:aaid:...
Submit by June 30 at 5PM ET. Learn more here: acrobat.adobe.com/id/urn:aaid:...
June 18, 2025 at 6:20 PM
It would be great if other journals did this
Blocks and blocks of San Diegans showing up to protest, chanting ‘This is what democracy looks like!’ 🇺🇸
June 14, 2025 at 8:02 PM
Blocks and blocks of San Diegans showing up to protest, chanting ‘This is what democracy looks like!’ 🇺🇸
