Jean-Paul Noel
@jpnoel.bsky.social
Assistant Prof. Department of Neuroscience, University of Minnesota. PI noel-lab.org. Causal inference, hidden state inference, multisensory integration, navigation, peri-personal space, computational psychiatry, ecological neuroscience
Reposted by Jean-Paul Noel
Want a party that actually fights back? Run for office. We’ll help you. runforwhat.net
Run for Something
Find offices you can run for
runforwhat.net
November 10, 2025 at 12:38 AM
Want a party that actually fights back? Run for office. We’ll help you. runforwhat.net
Reposted by Jean-Paul Noel
How do VTA DA neurons sculpt downstream representations to reinforce actions? VERY excited about our new preprint (by Alex Pan Vazquez & @czimmerman.bsky.social )
VTA dopamine neuron activity produces spatially organized value representations https://www.biorxiv.org/content/10.1101/2025.11.04.685995v1
November 7, 2025 at 8:46 PM
How do VTA DA neurons sculpt downstream representations to reinforce actions? VERY excited about our new preprint (by Alex Pan Vazquez & @czimmerman.bsky.social )
Nice write-up of some of our recent work! Thank you for the support @simonsfoundation.org !
Mice with autism-associated genetic variants don’t update their expectations as flexibly as their peers, finds a new study in Nature Neuroscience: https://www.simonsfoundation.org/mapping-mouse-brains-points-to-how-autism-can-affect-expectation-updating/ #science #neuroscience #autismresearch
Mapping Mouse Brains Points to How Autism Can Affect Expectation Updating
Mapping Mouse Brains Points to How Autism Can Affect Expectation Updating on Simons Foundation
www.simonsfoundation.org
October 23, 2025 at 6:52 PM
Nice write-up of some of our recent work! Thank you for the support @simonsfoundation.org !
Reposted by Jean-Paul Noel
The work with bats on barren, 7-acre Latham Island was Nachum Ulanovsky’s most complex undertaking yet.
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuroetholog...
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuroetholog...
October 16, 2025 at 6:15 PM
The work with bats on barren, 7-acre Latham Island was Nachum Ulanovsky’s most complex undertaking yet.
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuroetholog...
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuroetholog...
Reposted by Jean-Paul Noel
They’re using American tax dollars to fund infrastructure in Argentina because that’s where they’re all going to flee when we kick them out of office
After announcing a $20 billion bailout of Argentina, the White House now says it's pausing $18 billion in funding for NYC infrastructure projects
Russ Vought would love nothing more than to tear this country down to its studs
Russ Vought would love nothing more than to tear this country down to its studs
October 5, 2025 at 6:14 PM
They’re using American tax dollars to fund infrastructure in Argentina because that’s where they’re all going to flee when we kick them out of office
Reposted by Jean-Paul Noel
Our next profile is here! Dr. Christine Constantinople studies the neural mechanisms of decision-making. Follow the link below to learn more! 🧠
www.storiesofwin.org/profiles/202...
#StoriesOfWiN #WomenInNeuro
www.storiesofwin.org/profiles/202...
#StoriesOfWiN #WomenInNeuro
October 1, 2025 at 4:56 PM
Our next profile is here! Dr. Christine Constantinople studies the neural mechanisms of decision-making. Follow the link below to learn more! 🧠
www.storiesofwin.org/profiles/202...
#StoriesOfWiN #WomenInNeuro
www.storiesofwin.org/profiles/202...
#StoriesOfWiN #WomenInNeuro
Reposted by Jean-Paul Noel
How does the brain decide? 🧠
Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc.
After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up.
rdcu.be/eGUrv
Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc.
After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up.
rdcu.be/eGUrv
Transitions in dynamical regime and neural mode during perceptual decisions - Nature
Simultaneous recordings were made of hundreds of neurons in the rat frontal cortex and striatum, showing that decision commitment involves a rapid, coordinated transition in dynamical regime and neura...
www.nature.com
September 17, 2025 at 8:12 PM
How does the brain decide? 🧠
Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc.
After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up.
rdcu.be/eGUrv
Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc.
After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up.
rdcu.be/eGUrv
Reposted by Jean-Paul Noel
Multisensory coding of self-motion and its contribution to navigation — a Review by Dun Mao & Yong Gu
www.nature.com/articles/s41...
#neuroscience #neuroskyence
www.nature.com/articles/s41...
#neuroscience #neuroskyence
Multisensory coding of self-motion and its contribution to navigation - Nature Reviews Neuroscience
As an animal moves within its environment, self-motion signals are generated by the inner ear vestibular organs and the retina and transmitted to the CNS. In this Review, Mao and Gu describe how these...
www.nature.com
September 16, 2025 at 9:07 AM
Multisensory coding of self-motion and its contribution to navigation — a Review by Dun Mao & Yong Gu
www.nature.com/articles/s41...
#neuroscience #neuroskyence
www.nature.com/articles/s41...
#neuroscience #neuroskyence
Reposted by Jean-Paul Noel
Full professor complaining to an assistant professor on how hard it is to get funding nowadays
September 10, 2025 at 2:11 PM
Full professor complaining to an assistant professor on how hard it is to get funding nowadays
Reposted by Jean-Paul Noel
Reposted by Jean-Paul Noel
Two flagship papers from the International Brain Laboratory, now out in @Nature.com:
🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0
🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +
🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0
🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +
September 3, 2025 at 4:22 PM
Two flagship papers from the International Brain Laboratory, now out in @Nature.com:
🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0
🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +
🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0
🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +
Reposted by Jean-Paul Noel
The first complete activity map of a mammalian brain has revealed unprecedented insights into how decisions are made – and may even hint at the roots of intuition.
First map of mammal brain activity may have shown intuition in action
Scientists have mapped the activity that takes place across a mouse's entire brain as it decides how to complete a task - and the results could explain the origin of our gut feelings
www.newscientist.com
September 3, 2025 at 5:58 PM
The first complete activity map of a mammalian brain has revealed unprecedented insights into how decisions are made – and may even hint at the roots of intuition.
Reposted by Jean-Paul Noel
The @intlbrainlab.bsky.social published 2 papers today on their work to create a map of neural activity across the entire mouse brain. Learn more about the lab: https://www.simonsfoundation.org/2025/02/20/how-do-our-brains-make-decisions-the-international-brain-laboratory-is-closing-in-on-answers/
How Do Our Brains Make Decisions? The International Brain Laboratory Is Closing In on Answers
How Do Our Brains Make Decisions? The International Brain Laboratory Is Closing In on Answers on Simons Foundation
www.simonsfoundation.org
September 3, 2025 at 6:10 PM
The @intlbrainlab.bsky.social published 2 papers today on their work to create a map of neural activity across the entire mouse brain. Learn more about the lab: https://www.simonsfoundation.org/2025/02/20/how-do-our-brains-make-decisions-the-international-brain-laboratory-is-closing-in-on-answers/
Reposted by Jean-Paul Noel
The two key studies of the International Brain Laboratory @intlbrainlab.bsky.social are out today!
A brain-wide map of neural activity during complex behaviour
www.nature.com/articles/s41...
Brain-wide representations of prior information in mouse decision-making
www.nature.com/articles/s41...
A brain-wide map of neural activity during complex behaviour
www.nature.com/articles/s41...
Brain-wide representations of prior information in mouse decision-making
www.nature.com/articles/s41...
A brain-wide map of neural activity during complex behaviour - Nature
The International Brain Laboratory presents a brain-wide electrophysiological map obtained from pooling data from 12 laboratories that performed the same standardized perceptual decision-making task i...
www.nature.com
September 3, 2025 at 3:46 PM
The two key studies of the International Brain Laboratory @intlbrainlab.bsky.social are out today!
A brain-wide map of neural activity during complex behaviour
www.nature.com/articles/s41...
Brain-wide representations of prior information in mouse decision-making
www.nature.com/articles/s41...
A brain-wide map of neural activity during complex behaviour
www.nature.com/articles/s41...
Brain-wide representations of prior information in mouse decision-making
www.nature.com/articles/s41...
Reposted by Jean-Paul Noel
A show of bipartisan support for NIH. Basically flat except for ARPA-H.
The President’s budget proposal basically ignored (as it should have been).
The President’s budget proposal basically ignored (as it should have been).
House LHHC bill is out. Lots of hits to HHS, but the top line number for NIH is 1% decrease, mostly due to cuts ARPA-H. This seems like a huge rejection of the president's budget request.
democrats-appropriations.house.gov
September 2, 2025 at 12:37 AM
A show of bipartisan support for NIH. Basically flat except for ARPA-H.
The President’s budget proposal basically ignored (as it should have been).
The President’s budget proposal basically ignored (as it should have been).
Reposted by Jean-Paul Noel
A must-read, must-share piece - clearly deconstructing the shoddy science of the Geiers (who are inexplicably in charge of studies at HHS).
Consider this an early warning for what lies ahead. 🛟🩺🧪
www.nytimes.com/interactive/...
Consider this an early warning for what lies ahead. 🛟🩺🧪
www.nytimes.com/interactive/...
Opinion | The Playbook Used to ‘Prove’ Vaccines Cause Autism (Gift Article)
Data can easily be manipulated to show a causation that doesn’t exist.
www.nytimes.com
August 19, 2025 at 12:40 PM
A must-read, must-share piece - clearly deconstructing the shoddy science of the Geiers (who are inexplicably in charge of studies at HHS).
Consider this an early warning for what lies ahead. 🛟🩺🧪
www.nytimes.com/interactive/...
Consider this an early warning for what lies ahead. 🛟🩺🧪
www.nytimes.com/interactive/...
Reposted by Jean-Paul Noel
Congrats to this neuro-leaning @simonsfoundation.org physics & math collaboration on the science of learning. NeuroAI - exciting!
www.simonsfoundation.org/2025/08/18/s...
www.simonsfoundation.org/2025/08/18/s...
Simons Foundation Launches Collaboration on the Physics of Learning and Neural Computation
Simons Foundation Launches Collaboration on the Physics of Learning and Neural Computation on Simons Foundation
www.simonsfoundation.org
August 18, 2025 at 6:52 PM
Congrats to this neuro-leaning @simonsfoundation.org physics & math collaboration on the science of learning. NeuroAI - exciting!
www.simonsfoundation.org/2025/08/18/s...
www.simonsfoundation.org/2025/08/18/s...
Reposted by Jean-Paul Noel
Please sign! Science funding got strong support from the Senate but is now in the House! docs.google.com/forms/d/e/1F...
CE-Letter to Congress Requesting Protection of Science Funding in the FY26 Budget
To: The Honorable Members of the United States Congress
Dear Honorable Senators and Representatives,
We write in our individual capacities as U.S. citizens to urge you to prevent the far-reaching cons...
docs.google.com
August 17, 2025 at 4:21 PM
Please sign! Science funding got strong support from the Senate but is now in the House! docs.google.com/forms/d/e/1F...
Reposted by Jean-Paul Noel
I'll admit, I was skeptical when they said Gemini was just like a bunch of PhDs. But I gotta admit they nailed it.
August 17, 2025 at 1:51 PM
I'll admit, I was skeptical when they said Gemini was just like a bunch of PhDs. But I gotta admit they nailed it.
Reposted by Jean-Paul Noel
Reposted by Jean-Paul Noel
BREAKING NEWS: a government watchdog confirmed the Trump administration is breaking the law by blocking NIH funds.
How many kids with cancer or grandmas with Alzheimer’s have to get closer to death while crucial research is stalled?
Trump must end this illegal funding freeze.
How many kids with cancer or grandmas with Alzheimer’s have to get closer to death while crucial research is stalled?
Trump must end this illegal funding freeze.
August 5, 2025 at 10:46 PM
BREAKING NEWS: a government watchdog confirmed the Trump administration is breaking the law by blocking NIH funds.
How many kids with cancer or grandmas with Alzheimer’s have to get closer to death while crucial research is stalled?
Trump must end this illegal funding freeze.
How many kids with cancer or grandmas with Alzheimer’s have to get closer to death while crucial research is stalled?
Trump must end this illegal funding freeze.
Reposted by Jean-Paul Noel
I’m very excited to share that I will join the University of Utah Department of Neurobiology as an Assistant Professor in Jan 2026!! 🎉🏔️🏜️
My lab will focus on body–brain interactions in learning & memory — how do signals from our internal organs remodel the brain & behavior?
My lab will focus on body–brain interactions in learning & memory — how do signals from our internal organs remodel the brain & behavior?
July 8, 2025 at 4:48 PM
I’m very excited to share that I will join the University of Utah Department of Neurobiology as an Assistant Professor in Jan 2026!! 🎉🏔️🏜️
My lab will focus on body–brain interactions in learning & memory — how do signals from our internal organs remodel the brain & behavior?
My lab will focus on body–brain interactions in learning & memory — how do signals from our internal organs remodel the brain & behavior?
Reposted by Jean-Paul Noel
Come work in my dept! We are hiring a lecturer in psychology (ideally speaking Dutch) @leidenpsychology.bsky.social
www.academictransfer.com/en/jobs/3529...
www.academictransfer.com/en/jobs/3529...
Docent Psychologie
De Sectie Cognitieve Psychologie van het Instituut Psychologie van de Faculteit Sociale Wetenschappen heeft een vacature voor Docent Psychologie Dit ga je doen Als docent psychologie ga je onderwijs v...
www.academictransfer.com
June 20, 2025 at 11:02 AM
Come work in my dept! We are hiring a lecturer in psychology (ideally speaking Dutch) @leidenpsychology.bsky.social
www.academictransfer.com/en/jobs/3529...
www.academictransfer.com/en/jobs/3529...
Reposted by Jean-Paul Noel
Maybe he would only be able to rent part of Venice if he had to pay taxes.
Just kidding. With a net worth of $224.6 billion, he could pay $1 million per hour for the next 25 years and still be a multibillionaire (assuming no increase in wealth).
www.greenpeace.org/italy/storia...
Just kidding. With a net worth of $224.6 billion, he could pay $1 million per hour for the next 25 years and still be a multibillionaire (assuming no increase in wealth).
www.greenpeace.org/italy/storia...
June 23, 2025 at 8:16 PM
Maybe he would only be able to rent part of Venice if he had to pay taxes.
Just kidding. With a net worth of $224.6 billion, he could pay $1 million per hour for the next 25 years and still be a multibillionaire (assuming no increase in wealth).
www.greenpeace.org/italy/storia...
Just kidding. With a net worth of $224.6 billion, he could pay $1 million per hour for the next 25 years and still be a multibillionaire (assuming no increase in wealth).
www.greenpeace.org/italy/storia...
Reposted by Jean-Paul Noel
Mice harboring mutations in Fmr1, Cntnap2 or Shank3B show a blunted update of priors during decision-making, suggesting that distinct genetic instantiations of ASD may yield common neurophysiological and behavioral phenotypes
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A common computational and neural anomaly across mouse models of autism - Nature Neuroscience
Noel et al. show aberrant updating of expectations in three distinct mouse models of autism spectrum disorder. Brain-wide neurophysiology data suggest this stems from excess units encoding deviations ...
www.nature.com
June 9, 2025 at 9:02 PM
Mice harboring mutations in Fmr1, Cntnap2 or Shank3B show a blunted update of priors during decision-making, suggesting that distinct genetic instantiations of ASD may yield common neurophysiological and behavioral phenotypes
www.nature.com/articles/s41...
www.nature.com/articles/s41...