Canada has formally lost its measles elimination status, the country’s public health agency announced, triggering the loss of that status throughout all of the Americas.

Purpose Linezolid serum concentrations in critically ill patients show high variability. In this retrospective study, we analysed the linezolid plasma through levels (Cmin) in patients on intensive ca...

Previously considered a rare opportunistic pathogen, Serratia is now an emerging cause of bacteraemia. We compared the risk factors and outcomes of patients with Serratia bacteraemia relative to other...

James Cashman, Paul McCarroll, Peter Choong, Pedro Ivo Carvalho, Nicolaas Budhiparama, Ewout S Veltman, David Dewar, Mehmet Kursat Yilmaz

Just back from a visit to the Infectious Diseases Division at Johns Hopkins, thanks to the kind invitation of current ID chief Dr. Amita Gupta and her predecessor, Dr. David Thomas. On a personal note...

This white paper, devised from the Infectious Diseases Society of America's National Training Program Director annual meeting, outlines practical strategie

Tuberculosis (TB) is a major global health concern, with long-term complications persisting even after successful treatment. Chronic pulmonary aspergillosis (CPA) is a progressive fungal disease that frequently develops in TB survivors, contributing to post-TB lung disease. The true burden of CPA among patients with TB remains unclear due to diagnostic challenges and limited data. We aimed to estimate the prevalence of CPA among patients with prior or concurrent TB.MethodsWe conducted a systematic search in PubMed, Cochrane Library, Web of Science, and Science Direct through 10 January 2025. Eligible cohort and cross-sectional studies reported CPA prevalence in patients diagnosed with TB based on clinical symptoms, radiographic abnormalities, and microbiological evidence. Three reviewers screened 1575 unique studies, assessed 118 full texts, and included 22 studies (2884 patients). We conducted a meta-analysis using a random-effects model to estimate pooled CPA prevalence, with subgroup and meta-regression analyses exploring factors influencing CPA burden.ResultsCPA prevalence varied by timing of assessment and symptom status. Among all patients with TB, CPA prevalence was 9% (95% confidence interval [CI]: 6%–12%) during treatment and 13% (95% CI: 6%–27%) posttreatment. Among patients with persistent respiratory symptoms, CPA prevalence was 20% during treatment and 48% (95% CI: 36%–61%) posttreatment. Meta-regression identified symptom status and timing of CPA assessment as significant predictors of CPA prevalence.ConclusionsThe high CPA burden among TB survivors, particularly those with persistent symptoms, underscores the need for routine CPA screening in TB programs. Early detection and targeted interventions could reduce respiratory complications and improve patient outcomes.

Peripheral intravenous catheters (PIVCs) are widely used in hospitals and account for up to one-third of hospital-onset Staphylococcus aureus bacterem…

The dramatic shift in oversight comes at a time when the U.S. has never been more reliant on foreign food, which accounts for the vast majority of the nation’s seafood and more than half its fresh fru...

YouTube video by Dr. Glaucomflecken

This cohort study compares risk of surgical site infection among patients treated with β-lactam vs non–β-lactam surgical antimicrobial prophylaxis.