Antibiotic Steward 🅱️C🆔🅿️🌟
@absteward.bsky.social
Stay up-to-date in Infectious Diseases, Clinical Pharmacist, Antibiotics, #IDTwitter t✨p influencer #interstellar #dune
🌹❤️Misk #idsky #medsky #AMSsky #idxposts
Bassam Ghanem,PharmD MS BCPS BCIDP
🌹❤️Misk #idsky #medsky #AMSsky #idxposts
Bassam Ghanem,PharmD MS BCPS BCIDP
Pinned
🎖️📄Top infectious disease journal articles from 2025 is out! May be good for a quick review to see if you missed anything or if you need to pick a journal club article. #pharmacist #infectiousdiseases #pharmacyschool #FYP #IDstewardship @absteward.bsky.social
www.idstewardship.com/year-in-revi...
www.idstewardship.com/year-in-revi...
As 2025 comes to a close, it has been another remarkable year for ID research. From groundbreaking vaccine studies to innovative antibiotic strategies and simplified TB regimens,this year has delivered insights that challenge dogma,refine clinical practice & advance global stewardship efforts #idsky
As 2025 comes to a close, it has been another remarkable year for ID research. From groundbreaking vaccine studies to innovative antibiotic strategies and simplified TB regimens,this year has delivered insights that challenge dogma,refine clinical practice & advance global stewardship efforts #idsky
🎖️📄Top infectious disease journal articles from 2025 is out! May be good for a quick review to see if you missed anything or if you need to pick a journal club article. #pharmacist #infectiousdiseases #pharmacyschool #FYP #IDstewardship @absteward.bsky.social
www.idstewardship.com/year-in-revi...
www.idstewardship.com/year-in-revi...
December 29, 2025 at 5:49 PM
As 2025 comes to a close, it has been another remarkable year for ID research. From groundbreaking vaccine studies to innovative antibiotic strategies and simplified TB regimens,this year has delivered insights that challenge dogma,refine clinical practice & advance global stewardship efforts #idsky
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
🎖️📄Top infectious disease journal articles from 2025 is out! May be good for a quick review to see if you missed anything or if you need to pick a journal club article. #pharmacist #infectiousdiseases #pharmacyschool #FYP #IDstewardship @absteward.bsky.social
www.idstewardship.com/year-in-revi...
www.idstewardship.com/year-in-revi...
December 29, 2025 at 5:25 PM
🎖️📄Top infectious disease journal articles from 2025 is out! May be good for a quick review to see if you missed anything or if you need to pick a journal club article. #pharmacist #infectiousdiseases #pharmacyschool #FYP #IDstewardship @absteward.bsky.social
www.idstewardship.com/year-in-revi...
www.idstewardship.com/year-in-revi...
🆕⚡🧠HARVEST TRIAL:More Rifampin,Same Fate: High-Dose Rifampin Fails to Shift the Needle in TB Meningitis,NEJM,2025
Despite better theoretical CNS penetration,high-dose oral rifampin did not improve survival in adult TB meningitis & potential harm cannot be excluded #idsky
www.nejm.org/doi/full/10....
Despite better theoretical CNS penetration,high-dose oral rifampin did not improve survival in adult TB meningitis & potential harm cannot be excluded #idsky
www.nejm.org/doi/full/10....
Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis | NEJM
Tuberculous meningitis is often lethal, and many survivors have disabilities despite antimicrobial treatment and adjunctive glucocorticoid therapy. Standard-dose rifampin has limited central nervou...
www.nejm.org
December 18, 2025 at 3:51 AM
🆕⚡🧠HARVEST TRIAL:More Rifampin,Same Fate: High-Dose Rifampin Fails to Shift the Needle in TB Meningitis,NEJM,2025
Despite better theoretical CNS penetration,high-dose oral rifampin did not improve survival in adult TB meningitis & potential harm cannot be excluded #idsky
www.nejm.org/doi/full/10....
Despite better theoretical CNS penetration,high-dose oral rifampin did not improve survival in adult TB meningitis & potential harm cannot be excluded #idsky
www.nejm.org/doi/full/10....
⚡🫀 Beyond Dogma: Battle of the Unproven: Rifampicin vs Gentamicin in Staph PVE — A Shot in the Dark, JAC-AMR, 2025
🔥 Key findings:
• ⚰️ Lower 1-year mortality with rifampicin: 31.3% vs 39.9% (HR 0.71; 95% CI 0.54–0.94) #IDSky #EMIMCC
academic.oup.com/jacamr/artic...
🔥 Key findings:
• ⚰️ Lower 1-year mortality with rifampicin: 31.3% vs 39.9% (HR 0.71; 95% CI 0.54–0.94) #IDSky #EMIMCC
academic.oup.com/jacamr/artic...
Comparative effectiveness of adjunctive rifampicin versus gentamicin for prosthetic valve endocarditis due to Staphylococcus aureus
AbstractBackground. Although adjunctive rifampicin and/or gentamicin have been recommended for Staphylococcus aureus prosthetic valve endocarditis, evidenc
academic.oup.com
December 16, 2025 at 8:25 PM
⚡🫀 Beyond Dogma: Battle of the Unproven: Rifampicin vs Gentamicin in Staph PVE — A Shot in the Dark, JAC-AMR, 2025
🔥 Key findings:
• ⚰️ Lower 1-year mortality with rifampicin: 31.3% vs 39.9% (HR 0.71; 95% CI 0.54–0.94) #IDSky #EMIMCC
academic.oup.com/jacamr/artic...
🔥 Key findings:
• ⚰️ Lower 1-year mortality with rifampicin: 31.3% vs 39.9% (HR 0.71; 95% CI 0.54–0.94) #IDSky #EMIMCC
academic.oup.com/jacamr/artic...
A New Era for Gonorrhea
FDA Approves Two Oral Therapies for the treatment of Uncomplicated Urogenital Gonorrhea ,December 2025.
✅Nuzolvence (Zoliflodacin) granules that dissolve in water
✅Blujepa (Gepotidacin) oral tablets
Cost?
Resistance? #IDSky #EMIMCC
FDA Approves Two Oral Therapies for the treatment of Uncomplicated Urogenital Gonorrhea ,December 2025.
✅Nuzolvence (Zoliflodacin) granules that dissolve in water
✅Blujepa (Gepotidacin) oral tablets
Cost?
Resistance? #IDSky #EMIMCC
FDA approval 📢🔥
US FDA approved Nuzolvence (zoliflodacin) granules that dissolve in water. This medicine can treat uncomplicated urogenital gonorrhea in adults and children 12 years and older who weigh at least 77 pounds.
2 new oral Abx for gonorrhea #idsky
gepotidacin
www.fda.gov/news-events/...
US FDA approved Nuzolvence (zoliflodacin) granules that dissolve in water. This medicine can treat uncomplicated urogenital gonorrhea in adults and children 12 years and older who weigh at least 77 pounds.
2 new oral Abx for gonorrhea #idsky
gepotidacin
www.fda.gov/news-events/...
FDA Approves Two Oral Therapies to Treat Gonorrhea
The U.S. Food and Drug Administration recently approved two new oral medicines to treat a common sexually transmitted infection called gonorrhea.
www.fda.gov
December 13, 2025 at 2:36 PM
FDA approval 📢🔥
US FDA approved Nuzolvence (zoliflodacin) granules that dissolve in water. This medicine can treat uncomplicated urogenital gonorrhea in adults and children 12 years and older who weigh at least 77 pounds.
2 new oral Abx for gonorrhea #idsky
gepotidacin
www.fda.gov/news-events/...
US FDA approved Nuzolvence (zoliflodacin) granules that dissolve in water. This medicine can treat uncomplicated urogenital gonorrhea in adults and children 12 years and older who weigh at least 77 pounds.
2 new oral Abx for gonorrhea #idsky
gepotidacin
www.fda.gov/news-events/...
FDA Approves Two Oral Therapies to Treat Gonorrhea
The U.S. Food and Drug Administration recently approved two new oral medicines to treat a common sexually transmitted infection called gonorrhea.
www.fda.gov
December 13, 2025 at 8:16 AM
FDA approval 📢🔥
US FDA approved Nuzolvence (zoliflodacin) granules that dissolve in water. This medicine can treat uncomplicated urogenital gonorrhea in adults and children 12 years and older who weigh at least 77 pounds.
2 new oral Abx for gonorrhea #idsky
gepotidacin
www.fda.gov/news-events/...
US FDA approved Nuzolvence (zoliflodacin) granules that dissolve in water. This medicine can treat uncomplicated urogenital gonorrhea in adults and children 12 years and older who weigh at least 77 pounds.
2 new oral Abx for gonorrhea #idsky
gepotidacin
www.fda.gov/news-events/...
FDA approval 📢🔥
U.S. FDA.has approved **Blujepa (gepotidacin)**, a first-in-class oral antibiotic, for the treatment of **uncomplicated urogenital gonorrhoea in adults & adolescents aged 12 and older weighing at least 45 kg #IDsky #EMIMCC
www.reuters.com/business/hea...
U.S. FDA.has approved **Blujepa (gepotidacin)**, a first-in-class oral antibiotic, for the treatment of **uncomplicated urogenital gonorrhoea in adults & adolescents aged 12 and older weighing at least 45 kg #IDsky #EMIMCC
www.reuters.com/business/hea...
December 11, 2025 at 10:43 PM
FDA approval 📢🔥
U.S. FDA.has approved **Blujepa (gepotidacin)**, a first-in-class oral antibiotic, for the treatment of **uncomplicated urogenital gonorrhoea in adults & adolescents aged 12 and older weighing at least 45 kg #IDsky #EMIMCC
www.reuters.com/business/hea...
U.S. FDA.has approved **Blujepa (gepotidacin)**, a first-in-class oral antibiotic, for the treatment of **uncomplicated urogenital gonorrhoea in adults & adolescents aged 12 and older weighing at least 45 kg #IDsky #EMIMCC
www.reuters.com/business/hea...
🆕⚡🧠 Short-Course Prophylaxis: Early VAP Slashed, No Mortality Gain| Infection| 2025
Short-course antibiotic prophylaxis in high-risk acute brain injury patients reduces early and overall VAP and shortens LOS—but doesn’t improve mortality
Cc @pulmcrit.bsky.social
link.springer.com/article/10.1...
Short-course antibiotic prophylaxis in high-risk acute brain injury patients reduces early and overall VAP and shortens LOS—but doesn’t improve mortality
Cc @pulmcrit.bsky.social
link.springer.com/article/10.1...
Effectiveness of antibiotic prophylaxis for ventilator-associated pneumonia in acute brain injury: a systematic review and meta-analysis - Infection
Background Ventilator-associated pneumonia (VAP) affects 30–50% of mechanically ventilated patients with acute brain injury (ABI), exceeding general ICU rates (10–20%) due to aspiration risks and immu...
link.springer.com
December 11, 2025 at 9:21 PM
🆕⚡🧠 Short-Course Prophylaxis: Early VAP Slashed, No Mortality Gain| Infection| 2025
Short-course antibiotic prophylaxis in high-risk acute brain injury patients reduces early and overall VAP and shortens LOS—but doesn’t improve mortality
Cc @pulmcrit.bsky.social
link.springer.com/article/10.1...
Short-course antibiotic prophylaxis in high-risk acute brain injury patients reduces early and overall VAP and shortens LOS—but doesn’t improve mortality
Cc @pulmcrit.bsky.social
link.springer.com/article/10.1...
Chain of events:
🦨 Skunk → donor scratch → 🏥
• 1️⃣ Kidney recipient (MI) → 💀 5 wks: tremors, weakness, confusion, urinary incontinence
• 🧬 CDC: Rabies RNA detected postmortem (brain)
• 3️⃣ Cornea recipients → ✂️ Explant + 💉 PEP
• 370 exposed → 46 👩⚕️ HCWs needed 💉
4️⃣th U.S. organ-derived rabies case #idsky
🦨 Skunk → donor scratch → 🏥
• 1️⃣ Kidney recipient (MI) → 💀 5 wks: tremors, weakness, confusion, urinary incontinence
• 🧬 CDC: Rabies RNA detected postmortem (brain)
• 3️⃣ Cornea recipients → ✂️ Explant + 💉 PEP
• 370 exposed → 46 👩⚕️ HCWs needed 💉
4️⃣th U.S. organ-derived rabies case #idsky
🚨🦠 Tragic: A kidney recipient died of rabies — human-to-human transmission via organ transplant
Although rabies is usually transmitted by animal bites🐾,it can rarely pass through organs
The donor had mild encephalopathy… until family recalled a tiny detail:a skunk scratch
www.cdc.gov/mmwr/volumes...
Although rabies is usually transmitted by animal bites🐾,it can rarely pass through organs
The donor had mild encephalopathy… until family recalled a tiny detail:a skunk scratch
www.cdc.gov/mmwr/volumes...
Human-to-Human Rabies Transmission via Solid Organ...
This report describes the public health response to a patient who died after transplantation with an organ from a donor with undiagnosed rabies.
www.cdc.gov
December 8, 2025 at 6:06 PM
Chain of events:
🦨 Skunk → donor scratch → 🏥
• 1️⃣ Kidney recipient (MI) → 💀 5 wks: tremors, weakness, confusion, urinary incontinence
• 🧬 CDC: Rabies RNA detected postmortem (brain)
• 3️⃣ Cornea recipients → ✂️ Explant + 💉 PEP
• 370 exposed → 46 👩⚕️ HCWs needed 💉
4️⃣th U.S. organ-derived rabies case #idsky
🦨 Skunk → donor scratch → 🏥
• 1️⃣ Kidney recipient (MI) → 💀 5 wks: tremors, weakness, confusion, urinary incontinence
• 🧬 CDC: Rabies RNA detected postmortem (brain)
• 3️⃣ Cornea recipients → ✂️ Explant + 💉 PEP
• 370 exposed → 46 👩⚕️ HCWs needed 💉
4️⃣th U.S. organ-derived rabies case #idsky
🚨🦠 Tragic: A kidney recipient died of rabies — human-to-human transmission via organ transplant
Although rabies is usually transmitted by animal bites🐾,it can rarely pass through organs
The donor had mild encephalopathy… until family recalled a tiny detail:a skunk scratch
www.cdc.gov/mmwr/volumes...
Although rabies is usually transmitted by animal bites🐾,it can rarely pass through organs
The donor had mild encephalopathy… until family recalled a tiny detail:a skunk scratch
www.cdc.gov/mmwr/volumes...
Human-to-Human Rabies Transmission via Solid Organ...
This report describes the public health response to a patient who died after transplantation with an organ from a donor with undiagnosed rabies.
www.cdc.gov
December 8, 2025 at 5:52 PM
🚨🦠 Tragic: A kidney recipient died of rabies — human-to-human transmission via organ transplant
Although rabies is usually transmitted by animal bites🐾,it can rarely pass through organs
The donor had mild encephalopathy… until family recalled a tiny detail:a skunk scratch
www.cdc.gov/mmwr/volumes...
Although rabies is usually transmitted by animal bites🐾,it can rarely pass through organs
The donor had mild encephalopathy… until family recalled a tiny detail:a skunk scratch
www.cdc.gov/mmwr/volumes...
Finally, the classically recommended ‘4-to-6-week’ regimen of either FQs or TMP-SMX is not based on solid evidence, as no studies directly assessing 5 or 6 weeks of these Abx. Only fosfo was studied for durations over 4 weeks.
🆕⚡🧬 How Long Is Long Enough? — CBP Antibiotic Durations Still Built on Sand | CMI Communications, 2025
Current 4–6 wk FQ/TMP-SMX CBP regimens = thin evidence. Data mostly 4 wks (82%), shorter/longer durations poorly supported. RCTs needed #idsky #EMIMCC
www.sciencedirect.com:5037/science/arti...
Current 4–6 wk FQ/TMP-SMX CBP regimens = thin evidence. Data mostly 4 wks (82%), shorter/longer durations poorly supported. RCTs needed #idsky #EMIMCC
www.sciencedirect.com:5037/science/arti...
December 7, 2025 at 5:49 PM
Finally, the classically recommended ‘4-to-6-week’ regimen of either FQs or TMP-SMX is not based on solid evidence, as no studies directly assessing 5 or 6 weeks of these Abx. Only fosfo was studied for durations over 4 weeks.
🆕⚡🧬 How Long Is Long Enough? — CBP Antibiotic Durations Still Built on Sand | CMI Communications, 2025
Current 4–6 wk FQ/TMP-SMX CBP regimens = thin evidence. Data mostly 4 wks (82%), shorter/longer durations poorly supported. RCTs needed #idsky #EMIMCC
www.sciencedirect.com:5037/science/arti...
Current 4–6 wk FQ/TMP-SMX CBP regimens = thin evidence. Data mostly 4 wks (82%), shorter/longer durations poorly supported. RCTs needed #idsky #EMIMCC
www.sciencedirect.com:5037/science/arti...
December 7, 2025 at 5:33 PM
🆕⚡🧬 How Long Is Long Enough? — CBP Antibiotic Durations Still Built on Sand | CMI Communications, 2025
Current 4–6 wk FQ/TMP-SMX CBP regimens = thin evidence. Data mostly 4 wks (82%), shorter/longer durations poorly supported. RCTs needed #idsky #EMIMCC
www.sciencedirect.com:5037/science/arti...
Current 4–6 wk FQ/TMP-SMX CBP regimens = thin evidence. Data mostly 4 wks (82%), shorter/longer durations poorly supported. RCTs needed #idsky #EMIMCC
www.sciencedirect.com:5037/science/arti...
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Non pay walled link: authors.elsevier.com/a/1mCdH3AjoX...
authors.elsevier.com
December 7, 2025 at 3:32 AM
Non pay walled link: authors.elsevier.com/a/1mCdH3AjoX...
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
On an otherwise pretty dark day for ID and public health, great to see this is out.
Thanks to my Co-Leads ("the Michaels") and special thanks to Dipleen Kaur and the IDSA Staff!
TL;DR: use a scoring system for GAS.
@idsainfo.bsky.social @nuintmed.bsky.social
academic.oup.com/cid/advance-...
Thanks to my Co-Leads ("the Michaels") and special thanks to Dipleen Kaur and the IDSA Staff!
TL;DR: use a scoring system for GAS.
@idsainfo.bsky.social @nuintmed.bsky.social
academic.oup.com/cid/advance-...
December 6, 2025 at 12:09 AM
On an otherwise pretty dark day for ID and public health, great to see this is out.
Thanks to my Co-Leads ("the Michaels") and special thanks to Dipleen Kaur and the IDSA Staff!
TL;DR: use a scoring system for GAS.
@idsainfo.bsky.social @nuintmed.bsky.social
academic.oup.com/cid/advance-...
Thanks to my Co-Leads ("the Michaels") and special thanks to Dipleen Kaur and the IDSA Staff!
TL;DR: use a scoring system for GAS.
@idsainfo.bsky.social @nuintmed.bsky.social
academic.oup.com/cid/advance-...
🆕🔥State of art review article by 🌟 s
@drtoddlee.bsky.social @steventong.bsky.social
Navigating the Challenges in Staphylococcus aureus Bloodstream Infection: A Practical Guide to Management #idsky #EMIMCC
www.sciencedirect.com/science/arti...
@drtoddlee.bsky.social @steventong.bsky.social
Navigating the Challenges in Staphylococcus aureus Bloodstream Infection: A Practical Guide to Management #idsky #EMIMCC
www.sciencedirect.com/science/arti...
December 6, 2025 at 12:34 PM
🆕🔥State of art review article by 🌟 s
@drtoddlee.bsky.social @steventong.bsky.social
Navigating the Challenges in Staphylococcus aureus Bloodstream Infection: A Practical Guide to Management #idsky #EMIMCC
www.sciencedirect.com/science/arti...
@drtoddlee.bsky.social @steventong.bsky.social
Navigating the Challenges in Staphylococcus aureus Bloodstream Infection: A Practical Guide to Management #idsky #EMIMCC
www.sciencedirect.com/science/arti...
🆕⚡🔥🧬 BCID2 on Fire — Slashing Vancomycin Time in Staph Bacteremia Faster ID , Safer Care, Microbiology Spectrum, 2025 #IDSky #EMIMCC
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Clinical impact of BioFire Blood Culture Identification 2 implementation in patients with Staphylococcus bacteremia | Microbiology Spectrum
PCR-based blood culture testing with concurrent antimicrobial stewardship program
review continues to facilitate the initiation of pathogen-targeted antimicrobials
in a shorter amount of time compared...
journals.asm.org
December 5, 2025 at 8:20 PM
🆕⚡🔥🧬 BCID2 on Fire — Slashing Vancomycin Time in Staph Bacteremia Faster ID , Safer Care, Microbiology Spectrum, 2025 #IDSky #EMIMCC
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
🆕⚡🦠 Aztreonam-Avibactam — The Undisputed Hero 🏆 Tackling MBLs Like a Pro
🐯 Tigecycline strong & reliable not in BSI
🐴 Cefiderocol ,Once a Trojan Horse, not the soldier we hoped for
Cefepime-Taniborbactam🎯MBLs, yet resistance strikes with tricky combos #idsky #EMIMCC
journals.asm.org/doi/10.1128/...
🐯 Tigecycline strong & reliable not in BSI
🐴 Cefiderocol ,Once a Trojan Horse, not the soldier we hoped for
Cefepime-Taniborbactam🎯MBLs, yet resistance strikes with tricky combos #idsky #EMIMCC
journals.asm.org/doi/10.1128/...
Activity of aztreonam-avibactam, cefiderocol, and cefepime-taniborbactam against a global collection of genetically characterized metallo-β-lactamase-producing Enterobacterales | Antimicrobial Agents ...
Acquired metallo-β-lactamases (MBLs) emerged in the early 1990s with the description
of IMP-1 in a Serratia marcescens isolate from Japan (1). The description of this enzyme was followed by the report...
journals.asm.org
December 5, 2025 at 3:10 PM
🆕⚡🦠 Aztreonam-Avibactam — The Undisputed Hero 🏆 Tackling MBLs Like a Pro
🐯 Tigecycline strong & reliable not in BSI
🐴 Cefiderocol ,Once a Trojan Horse, not the soldier we hoped for
Cefepime-Taniborbactam🎯MBLs, yet resistance strikes with tricky combos #idsky #EMIMCC
journals.asm.org/doi/10.1128/...
🐯 Tigecycline strong & reliable not in BSI
🐴 Cefiderocol ,Once a Trojan Horse, not the soldier we hoped for
Cefepime-Taniborbactam🎯MBLs, yet resistance strikes with tricky combos #idsky #EMIMCC
journals.asm.org/doi/10.1128/...
👉 Evidence is limited, but reducing β-lactam doses too early in AKI may underdose critically ill patients at the worst possible time.
🛡️ Delayed dose reduction (after reassessing kidney recovery ~48H) might improve mortality—but better prospective studies are urgently needed #idsky #EMIMCC
🛡️ Delayed dose reduction (after reassessing kidney recovery ~48H) might improve mortality—but better prospective studies are urgently needed #idsky #EMIMCC
⚡💉Are We Jumping the Gun? Early Beta-Lactam Dose Cuts Risk Underdosing in AKI, Critical Care, 2025
link.springer.com/article/10.1...
Link to X post:
x.com/ABsteward/st...
#idsky #EMIMCC
link.springer.com/article/10.1...
Link to X post:
x.com/ABsteward/st...
#idsky #EMIMCC
Beta-lactam dose reductions in critically ill patients with acute kidney injury: a scoping review - Critical Care
Background Acute kidney injury is a common complication in critically ill patients, often coinciding with the need for antibiotic therapy. The dose of beta-lactam antibiotics is frequently adjusted an...
link.springer.com
December 5, 2025 at 9:51 AM
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Sounds like a temporary rift...but things need to change in the future or it will be likely to happen again due to problems with the methodology and execution
December 5, 2025 at 3:32 AM
Sounds like a temporary rift...but things need to change in the future or it will be likely to happen again due to problems with the methodology and execution
🆕⚡ A Temporary Rift or a Permanent Split? Why Didn’t IDSA Endorse the CAP Guidelines 2025 Update?
In 2025 IDSA disagreed because the new guidelines recommend routine antibiotics for viral-positive outpatients with comorbidities & inpatients with nonsevere CAP #IDSky
academic.oup.com/cid/article-...
In 2025 IDSA disagreed because the new guidelines recommend routine antibiotics for viral-positive outpatients with comorbidities & inpatients with nonsevere CAP #IDSky
academic.oup.com/cid/article-...
Infectious Diseases Society of America (IDSA) Position Statement: Why IDSA Did Not Endorse the Community-Acquired Pneumonia Guidelines 2025 Update
The Infectious Diseases Society of America (IDSA) did not endorse updated community-acquired pneumonia guidelines because they recommend antibiotics for pa
academic.oup.com
December 4, 2025 at 2:19 PM
🆕⚡ A Temporary Rift or a Permanent Split? Why Didn’t IDSA Endorse the CAP Guidelines 2025 Update?
In 2025 IDSA disagreed because the new guidelines recommend routine antibiotics for viral-positive outpatients with comorbidities & inpatients with nonsevere CAP #IDSky
academic.oup.com/cid/article-...
In 2025 IDSA disagreed because the new guidelines recommend routine antibiotics for viral-positive outpatients with comorbidities & inpatients with nonsevere CAP #IDSky
academic.oup.com/cid/article-...
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
In critically ill pts, avoid adjusting initial doses based solely on early bloodwork. When pts present to ED, SCr/eGFR may not accurately reflect kidney fxn. These early labs represent pre-treatment📷(before IV💧, Abxs & resus). W/ these interventions, SCr/eGFR often improves #emimcc #medsky #pharmsky
⚡💉Are We Jumping the Gun? Early Beta-Lactam Dose Cuts Risk Underdosing in AKI, Critical Care, 2025
link.springer.com/article/10.1...
Link to X post:
x.com/ABsteward/st...
#idsky #EMIMCC
link.springer.com/article/10.1...
Link to X post:
x.com/ABsteward/st...
#idsky #EMIMCC
Beta-lactam dose reductions in critically ill patients with acute kidney injury: a scoping review - Critical Care
Background Acute kidney injury is a common complication in critically ill patients, often coinciding with the need for antibiotic therapy. The dose of beta-lactam antibiotics is frequently adjusted an...
link.springer.com
December 3, 2025 at 10:51 PM
In critically ill pts, avoid adjusting initial doses based solely on early bloodwork. When pts present to ED, SCr/eGFR may not accurately reflect kidney fxn. These early labs represent pre-treatment📷(before IV💧, Abxs & resus). W/ these interventions, SCr/eGFR often improves #emimcc #medsky #pharmsky
🤔 I’ll admit — I’m still wrapping my head around DOOR in clinical trials. I’m used to P-values and classic non-inferiority, but DOOR feels different.
Breaking down the DOOR in DOTS RCT @cmicomms.bsky.social
#idsky #EMIMCC
www.sciencedirect.com/science/arti...
Breaking down the DOOR in DOTS RCT @cmicomms.bsky.social
#idsky #EMIMCC
www.sciencedirect.com/science/arti...
Breaking down the Desirability of Outcome Ranking (DOOR): unpacking the methodology behind the Dalbavancin as an Option for Treatment of Staphylococcus aureus Bacteremia (DOTS) trial
Desirability of Outcome Ranking (DOOR) outcomes such as the primary outcome of the DOTS (Dalbavancin as an Option for Treatment of Staphylococcus aure…
www.sciencedirect.com
December 3, 2025 at 8:57 PM
🤔 I’ll admit — I’m still wrapping my head around DOOR in clinical trials. I’m used to P-values and classic non-inferiority, but DOOR feels different.
Breaking down the DOOR in DOTS RCT @cmicomms.bsky.social
#idsky #EMIMCC
www.sciencedirect.com/science/arti...
Breaking down the DOOR in DOTS RCT @cmicomms.bsky.social
#idsky #EMIMCC
www.sciencedirect.com/science/arti...
🆕🎙️🔥Febrile Podcast just dropped!
✅ID Jedi @bradspellberg.bsky.social
✅Mini-cases OM,IE,Bacteremia
✅IV vs PO debates
✅Duration of therapy
✅Shmidelines Vs WikiGuideline
✅A must-listen for every antibiotic steward! #IDsky #EMIMCC
febrilepodcast.com/episodes/
open.spotify.com/episode/6dkJ...
✅ID Jedi @bradspellberg.bsky.social
✅Mini-cases OM,IE,Bacteremia
✅IV vs PO debates
✅Duration of therapy
✅Shmidelines Vs WikiGuideline
✅A must-listen for every antibiotic steward! #IDsky #EMIMCC
febrilepodcast.com/episodes/
open.spotify.com/episode/6dkJ...
December 3, 2025 at 8:25 PM
🆕🎙️🔥Febrile Podcast just dropped!
✅ID Jedi @bradspellberg.bsky.social
✅Mini-cases OM,IE,Bacteremia
✅IV vs PO debates
✅Duration of therapy
✅Shmidelines Vs WikiGuideline
✅A must-listen for every antibiotic steward! #IDsky #EMIMCC
febrilepodcast.com/episodes/
open.spotify.com/episode/6dkJ...
✅ID Jedi @bradspellberg.bsky.social
✅Mini-cases OM,IE,Bacteremia
✅IV vs PO debates
✅Duration of therapy
✅Shmidelines Vs WikiGuideline
✅A must-listen for every antibiotic steward! #IDsky #EMIMCC
febrilepodcast.com/episodes/
open.spotify.com/episode/6dkJ...
⚡💉Are We Jumping the Gun? Early Beta-Lactam Dose Cuts Risk Underdosing in AKI, Critical Care, 2025
link.springer.com/article/10.1...
Link to X post:
x.com/ABsteward/st...
#idsky #EMIMCC
link.springer.com/article/10.1...
Link to X post:
x.com/ABsteward/st...
#idsky #EMIMCC
Beta-lactam dose reductions in critically ill patients with acute kidney injury: a scoping review - Critical Care
Background Acute kidney injury is a common complication in critically ill patients, often coinciding with the need for antibiotic therapy. The dose of beta-lactam antibiotics is frequently adjusted an...
link.springer.com
December 3, 2025 at 6:53 PM
⚡💉Are We Jumping the Gun? Early Beta-Lactam Dose Cuts Risk Underdosing in AKI, Critical Care, 2025
link.springer.com/article/10.1...
Link to X post:
x.com/ABsteward/st...
#idsky #EMIMCC
link.springer.com/article/10.1...
Link to X post:
x.com/ABsteward/st...
#idsky #EMIMCC