Antibiotic Steward 🅱️C🆔🅿️🌟
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Antibiotic Steward 🅱️C🆔🅿️🌟
@absteward.bsky.social
Stay up-to-date in Infectious Diseases, Clinical Pharmacist, Antibiotics, #IDTwitter t✨p influencer #interstellar #dune
🌹❤️Misk #idsky #medsky #AMSsky #idxposts
Bassam Ghanem,PharmD MS BCPS BCIDP
Pinned
How much evidence is needed to revise established clinical practices? and, can data alone truly catalyze such shifts?
Our 🆕🔥 Article at @cidjournal.bsky.social with 🌟s @bradspellberg.bsky.social
Practicing With Intent: How to Teach an Old Dogma New Tricks #IDSky
academic.oup.com/cid/article/...
In high-income countries, up to 11.5% of adults report a penicillin allergy, and in high-risk groups prevalence can reach 35%. However, more than 90% of these labels are inaccurate, resulting in substantial clinical and public health consequences in hospitals and communities #idsky
🆕🔥State-of-the-Art Review with 🌟s @trubianojason.bsky.social : Antibiotic Allergy—A Multidisciplinary Approach to Delabeling #idsky
url: academic.oup.com/cid/article/...
November 7, 2025 at 2:37 PM
The misconception that antibiotic allergy assessment is solely the domain of allergists has led to complacency in clinical practice, yet verifying allergy histories should be a core competency for all physicians, particularly infectious diseases. #IDsky #EMIMCC
🆕🔥State-of-the-Art Review with 🌟s @trubianojason.bsky.social : Antibiotic Allergy—A Multidisciplinary Approach to Delabeling #idsky
url: academic.oup.com/cid/article/...
November 6, 2025 at 8:58 PM
Cross-reactivity of beta-lactams. A review of the beta-lactam cross-reactivity patterns based on key pharmacological structures and known clinical cross-reactivity #idsky
November 6, 2025 at 8:35 PM
🆕🔥State-of-the-Art Review with 🌟s @trubianojason.bsky.social : Antibiotic Allergy—A Multidisciplinary Approach to Delabeling #idsky
url: academic.oup.com/cid/article/...
November 6, 2025 at 8:09 PM
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
IV fosfo finally FDA approved in US for cUTI d/t E. coli or Kleb pneumo.
-How much will it cost?
-Folks willing to use it for Kleb (or other Enterobacterales) in the absence of CLSI BPs?
-Dose: 6G IV q8h…Tolerability in real-world? 🤔
Lots of questions to consider….
#IDSky #AMSsky
🔥Meitheal Pharmaceuticals Receives Approval from the US FDA for CONTEPO™ (fosfomycin) for injection in Patients ≥ 18 Years Having Complicated Urinary Tract Infections (cUTI),Including Acute Pyelonephritis🔥#idsky
www.businesswire.com/news/home/20...
November 5, 2025 at 4:57 PM
🔥Meitheal Pharmaceuticals Receives Approval from the US FDA for CONTEPO™ (fosfomycin) for injection in Patients ≥ 18 Years Having Complicated Urinary Tract Infections (cUTI),Including Acute Pyelonephritis🔥#idsky
www.businesswire.com/news/home/20...
November 5, 2025 at 4:32 AM
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Exciting to have more anti-Staph therapeutics, if a real effect. But don't look forward to a time when I have to manage a patient's anti-platelet drugs as ID...

(Rifampin interactions for TB and PJI are already plenty)

#IDSky
November 1, 2025 at 2:21 PM
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Toujours la même histoire :
1) Inventer un theorie.
2) Buter quelques souris sur l'autel de la science pour valider le concept. NDLR : à peine 10% de ces papiers ont des résultats reproductibles
3) Faire des etudes observationnelles bourrées de biais, dont le plus gros est le parti pris
November 1, 2025 at 10:19 AM
🆕🌟Excellent review article
P2Y12 inhibitors(eg clopidogrel,ticagrelor)in Staphylococcus aureus bacteraemia: current evidence and clinical implications
Coming soon: CLOPI-SNAP+ Clopido-SNAP #idsky #EMIMCC
www.thelancet.com/journals/lan...
P2Y12 inhibitors in Staphylococcus aureus bacteraemia: current evidence and clinical implications
Staphylococcus aureus bacteraemia presents a substantial clinical burden, with high rates of morbidity and mortality. Despite its severity, therapeutic advancements have been small in the past decade,...
www.thelancet.com
October 31, 2025 at 8:18 PM
Maybe AI Knows Something That We Do Not!
🆕💫 Cohort study
LLM accurately extracted presenting signs & symptoms from admission notes that clustered into syndromes differentially correlated with infection sources, MDR infections, and mortality #IDsky
jamanetwork.com/journals/jam...
Syndromic Analysis of Sepsis Cohorts Using Large Language Models
This cohort study compares the performance of a large language model against manual medical record review for extracting presenting signs and symptoms data from hospital admission notes and uses these...
jamanetwork.com
October 24, 2025 at 7:23 PM
A quick note: the article "incorrectly" refers to Candida parapsilosis as Pichia parapsilosis* and also omits Candida auris.
Is there any change in the name of C. parapsilosis?!
Just a reminder — taxonomy changes are tricky, and even peer review can miss them! #idsky
Updated nomenclature of common Candida species
Add Candida auris ⏭️Candidozyma auris.
The only one left is Candida albicans!
#IDsky
link.springer.com/article/10.1...
October 24, 2025 at 10:48 AM
Updated nomenclature of common Candida species
Add Candida auris ⏭️Candidozyma auris.
The only one left is Candida albicans!
#IDsky
link.springer.com/article/10.1...
October 23, 2025 at 11:21 PM
🆕🌟Excellent review
Invasive candidiasis in intensive care medicine: shaping the future of diagnosis and therapy #IDSky #EMIMCC
link.springer.com/article/10.1...
October 23, 2025 at 11:18 PM
CDI recurrence affects about 14% to 16% of patients with CDI, and the risk of recurrence increases with each CDI episode
🆕💫🌟 JAMA Insights
Recurrent Clostridioides difficile Infections
🟢Epidemiology and Risk factors
🟢Diagnosis
🟢Treatment
#IDSky #EMIMCC
jamanetwork.com/journals/jam...
October 20, 2025 at 5:00 PM
🆕🔥Seminar
Community-acquired pneumonia @thelancet.com #IDSky #EMIMCC
www.thelancet.com/journals/lan...
October 19, 2025 at 9:26 PM
One of the most anticipated RCT in ID #idsky
🆕🔥🔥CloCeBa RCT
Cloxacillin versus cefazolin for MSSA Bacteraemia
Cefazolin has a non-inferior efficacy regarding mortality, microbiological or clinical endpoints and was associated with a lower rate of serious adverse events #IDSky
www.thelancet.com/journals/lan...
October 19, 2025 at 4:41 AM
🆕🔥🔥CloCeBa RCT
Cloxacillin versus cefazolin for MSSA Bacteraemia
Cefazolin has a non-inferior efficacy regarding mortality, microbiological or clinical endpoints and was associated with a lower rate of serious adverse events #IDSky
www.thelancet.com/journals/lan...
October 19, 2025 at 4:34 AM
New Series 💎
Kicking off Antibiotic Stewardship Gems — quick, practical examples of how overtesting or overinterpreting can lead to unnecessary antibiotics use.
Stay tuned for more! #IDSky
Antibiotic Stewardship Gem 💎
A classic example where imaging prompts unnecessary testing:
Renal US:“mobile echogenic debris in urinary bladder—urinalysis to rule out infection”
No urinary symptoms➜ No UA, no culture, no antibiotics!
💭What other examples do you see in practice? #idsky
October 9, 2025 at 5:22 PM
Antibiotic Stewardship Gem 💎
A classic example where imaging prompts unnecessary testing:
Renal US:“mobile echogenic debris in urinary bladder—urinalysis to rule out infection”
No urinary symptoms➜ No UA, no culture, no antibiotics!
💭What other examples do you see in practice? #idsky
October 9, 2025 at 2:59 PM
Super interesting
🆕💫Do Aminopenicillins Have a Role in Treating Ampicillin-Resistant Enterococcus UTIs? #idsky
academic.oup.com/ofid/article...
Do Aminopenicillins Have a Role in Treating Ampicillin-Resistant Enterococcus UTIs?
Abstract. Urinary tract infections (UTIs) caused by Enterococcus species are a frequent clinical challenge. The rising prevalence of ampicillin resistance
academic.oup.com
October 8, 2025 at 10:23 PM
What’s in a name?” Even microbes carry stories. @cmicomms.bsky.social
is launching a new series exploring the people behind eponymous organisms—those whose names live on through microbes like Escherichia or Pasteurella. Open call for submissions #idsky
www.sciencedirect.com/science/arti...
The person behind the name – an open call for articles in a new series for CMI Communications
www.sciencedirect.com
October 8, 2025 at 5:01 PM
There is still a widespread belief that fever is harmful and that it should be
treated regardless of the underlying cause, which is not supported by clinical data.
🆕💫 Review: Fever in sepsis revisited: Is a little heat what we need? #idsky
academic.oup.com/ofid/article...
October 1, 2025 at 7:35 PM
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Intéressant...
Jamais vu encore en vrai..
Gentil rappel de toujours examiner les patients complètement, même si un diagnostic de choc sur pneumonie ou tableau abdominal semblant évident
Hypervirulent Klebsiella pneumoniae
(hvKP ) is a life-threatening pathogen that requires prompt clinical recognition!
🆕💫Tips for intinsvists: Hypervirulent Klebsiella pneumoniae
Delays kill eyes - and sometimes patients! #IDsky #EMIMCC
link.springer.com/article/10.1...
September 26, 2025 at 12:48 PM
hvKP is a life-& vision-threatening pathogen that should be promptly recognized
The triad of liver abscess + bacteremia + endophthalmitis should prompt immediate suspicion
Endophthalmitis is a medical emergency in septic patients with visual symptoms
Delays kill eyes and sometimes patients #microsky
Hypervirulent Klebsiella pneumoniae
(hvKP ) is a life-threatening pathogen that requires prompt clinical recognition!
🆕💫Tips for intinsvists: Hypervirulent Klebsiella pneumoniae
Delays kill eyes - and sometimes patients! #IDsky #EMIMCC
link.springer.com/article/10.1...
September 25, 2025 at 7:08 PM
Hypervirulent Klebsiella pneumoniae
(hvKP ) is a life-threatening pathogen that requires prompt clinical recognition!
🆕💫Tips for intinsvists: Hypervirulent Klebsiella pneumoniae
Delays kill eyes - and sometimes patients! #IDsky #EMIMCC
link.springer.com/article/10.1...
September 25, 2025 at 7:06 PM