Dr. David Boulware, MD MPH
@drboulware.bsky.social
Professor of Medicine at U of MN; Practicing infectious disease doc; budding mycologist; interested in cryptococcal & TB meningitis. Ran some RCTs during COVID, but more excited to return to focus on RCTs on HIV-related meningitis & advanced HIV disease
Should one be flattered when a published manuscript that is clearly AI written hallucinates and creates citations by you that you never wrote? Paper is not very good, omitting from the abstract use of a bad CrAg test which has poor performance.
What should one do? Contact editor? Or author?
What should one do? Contact editor? Or author?
November 9, 2025 at 1:04 PM
Should one be flattered when a published manuscript that is clearly AI written hallucinates and creates citations by you that you never wrote? Paper is not very good, omitting from the abstract use of a bad CrAg test which has poor performance.
What should one do? Contact editor? Or author?
What should one do? Contact editor? Or author?
Reposted by Dr. David Boulware, MD MPH
Career Opportunity! The California Department of Public Health, TB Control Branch is recruiting for an epidemiologist position.
Interested persons may apply via this website: sjobs.brassring.com/TGnewUI/Sear...
#Tuberculosis #TBSKy
Interested persons may apply via this website: sjobs.brassring.com/TGnewUI/Sear...
#Tuberculosis #TBSKy
Job Search Welcome | University of California San Francisco
Search for Internet job openings.
sjobs.brassring.com
October 24, 2025 at 5:23 PM
Career Opportunity! The California Department of Public Health, TB Control Branch is recruiting for an epidemiologist position.
Interested persons may apply via this website: sjobs.brassring.com/TGnewUI/Sear...
#Tuberculosis #TBSKy
Interested persons may apply via this website: sjobs.brassring.com/TGnewUI/Sear...
#Tuberculosis #TBSKy
Is there a fungus amongst us?
Dr. Fungus App for medical mycology on your phone.
Apple iOS Store: apps.apple.com/us/app/dr-fu...
Google Play Store: play.google.com/store/apps/d...
Dr. Fungus App for medical mycology on your phone.
Apple iOS Store: apps.apple.com/us/app/dr-fu...
Google Play Store: play.google.com/store/apps/d...
Dr. Fungus
The Dr. Fungus app serves as a companion to the official Dr. Fungus website, the Mycoses Study Group Education and Research Consortium resource for fungal disease education. This app provides up-to-d...
apps.apple.com
October 22, 2025 at 12:48 AM
Is there a fungus amongst us?
Dr. Fungus App for medical mycology on your phone.
Apple iOS Store: apps.apple.com/us/app/dr-fu...
Google Play Store: play.google.com/store/apps/d...
Dr. Fungus App for medical mycology on your phone.
Apple iOS Store: apps.apple.com/us/app/dr-fu...
Google Play Store: play.google.com/store/apps/d...
Insurance via ACA marketplace is projected to rise by 21% in Minnesota in 2026.
October 16, 2025 at 12:04 AM
Insurance via ACA marketplace is projected to rise by 21% in Minnesota in 2026.
No longer... CDC EIS RIF'ed.
October 11, 2025 at 1:57 AM
No longer... CDC EIS RIF'ed.
Reposted by Dr. David Boulware, MD MPH
Vaccine for typhoid, invasive Salmonella shows promise in phase 1 trial
Researchers say the investigational three-strain vaccine produced a strong immune response and was well-tolerated in its first human trial.
www.cidrap.umn.edu/s...
Researchers say the investigational three-strain vaccine produced a strong immune response and was well-tolerated in its first human trial.
www.cidrap.umn.edu/s...
October 8, 2025 at 8:31 PM
Vaccine for typhoid, invasive Salmonella shows promise in phase 1 trial
Researchers say the investigational three-strain vaccine produced a strong immune response and was well-tolerated in its first human trial.
www.cidrap.umn.edu/s...
Researchers say the investigational three-strain vaccine produced a strong immune response and was well-tolerated in its first human trial.
www.cidrap.umn.edu/s...
Predictive value of C-reactive protein for hospitalization and mortality among people with advanced HIV disease in Uganda receiving the WHO-recommended package of care
Nice paper by U of MN MD/PhD student Eli Schwartz on behalf of the ENCORE Team.
track.smtpsendmail.com/9032119/c?p=...
Nice paper by U of MN MD/PhD student Eli Schwartz on behalf of the ENCORE Team.
track.smtpsendmail.com/9032119/c?p=...
Predictive value of C-reactive protein for hospitalization and mortality among people with advanced HIV disease in Uganda receiving the WHO-recommended package of care
Among Ugandan outpatients with advanced HIV, elevated serum CRP (≥10 mg/L) predicted 30-day risk of opportunistic infection, hospitalization, and death. Ea
track.smtpsendmail.com
October 8, 2025 at 5:54 PM
Predictive value of C-reactive protein for hospitalization and mortality among people with advanced HIV disease in Uganda receiving the WHO-recommended package of care
Nice paper by U of MN MD/PhD student Eli Schwartz on behalf of the ENCORE Team.
track.smtpsendmail.com/9032119/c?p=...
Nice paper by U of MN MD/PhD student Eli Schwartz on behalf of the ENCORE Team.
track.smtpsendmail.com/9032119/c?p=...
Twin Cities Marathon Day.
Brunch with neighbors on front lawn cheering on runners.
Brunch with neighbors on front lawn cheering on runners.
October 5, 2025 at 2:51 PM
Twin Cities Marathon Day.
Brunch with neighbors on front lawn cheering on runners.
Brunch with neighbors on front lawn cheering on runners.
Excited to speak at UT Houston-Methodist on Friday on "Innovative Clinical Trial Designs in ID"
First time I have been back to Houston in 26 years. It's still hot... and even more buildings on medical campus.
First time I have been back to Houston in 26 years. It's still hot... and even more buildings on medical campus.
October 2, 2025 at 8:16 PM
Excited to speak at UT Houston-Methodist on Friday on "Innovative Clinical Trial Designs in ID"
First time I have been back to Houston in 26 years. It's still hot... and even more buildings on medical campus.
First time I have been back to Houston in 26 years. It's still hot... and even more buildings on medical campus.
Mycosis Study Group has released DrFungus app for phones as a reference companion for yeast and mold infections.
iPhone apps.apple.com/us/app/dr-fu...
Android play.google.com/store/apps/d...
App designed by Dr Matt Pullen. @msgerc.bsky.social
iPhone apps.apple.com/us/app/dr-fu...
Android play.google.com/store/apps/d...
App designed by Dr Matt Pullen. @msgerc.bsky.social
Dr. Fungus
The Dr. Fungus app serves as a companion to the official Dr. Fungus website, the Mycoses Study Group Education and Research Consortium resource for fungal disease education. This app provides up-to-d...
apps.apple.com
September 18, 2025 at 5:54 AM
Mycosis Study Group has released DrFungus app for phones as a reference companion for yeast and mold infections.
iPhone apps.apple.com/us/app/dr-fu...
Android play.google.com/store/apps/d...
App designed by Dr Matt Pullen. @msgerc.bsky.social
iPhone apps.apple.com/us/app/dr-fu...
Android play.google.com/store/apps/d...
App designed by Dr Matt Pullen. @msgerc.bsky.social
Reposted by Dr. David Boulware, MD MPH
More Than 20 Medical Groups Call For RFK Jr. To Resign
#IDSky #MedSky
www.idsociety.org/news--public...
#IDSky #MedSky
www.idsociety.org/news--public...
Joint statement calling for Secretary Kennedy resignation
www.idsociety.org
September 5, 2025 at 12:10 PM
More Than 20 Medical Groups Call For RFK Jr. To Resign
#IDSky #MedSky
www.idsociety.org/news--public...
#IDSky #MedSky
www.idsociety.org/news--public...
Reposted by Dr. David Boulware, MD MPH
Two studies, same signal👇
📊 COVID-OUT RCT: 41% ↓ long COVID with 14d metformin (1500 mg/day by Day 6).
📊 CID UK cohort (766k pts): 64% ↓ long COVID if metformin started within 90d.
Cheap, safe, generic drug. Replication across RCT + real world = 🔥
#MedSky
📊 COVID-OUT RCT: 41% ↓ long COVID with 14d metformin (1500 mg/day by Day 6).
📊 CID UK cohort (766k pts): 64% ↓ long COVID if metformin started within 90d.
Cheap, safe, generic drug. Replication across RCT + real world = 🔥
#MedSky
Effect of Metformin on the Risk of Post-coronavirus Disease 2019 Condition Among Individuals With Overweight or Obese: A Population-based Retrospective Cohort Study
Early metformin treatment in overweight or obese adults with recent coronavirus disease 2019 infection significantly reduces the risk of developing post–co
academic.oup.com
September 3, 2025 at 7:50 PM
Two studies, same signal👇
📊 COVID-OUT RCT: 41% ↓ long COVID with 14d metformin (1500 mg/day by Day 6).
📊 CID UK cohort (766k pts): 64% ↓ long COVID if metformin started within 90d.
Cheap, safe, generic drug. Replication across RCT + real world = 🔥
#MedSky
📊 COVID-OUT RCT: 41% ↓ long COVID with 14d metformin (1500 mg/day by Day 6).
📊 CID UK cohort (766k pts): 64% ↓ long COVID if metformin started within 90d.
Cheap, safe, generic drug. Replication across RCT + real world = 🔥
#MedSky
Are childhood vaccination requirement to attend public school (with a parental opt out) equivalent to slavery? No.
September 4, 2025 at 3:26 AM
Are childhood vaccination requirement to attend public school (with a parental opt out) equivalent to slavery? No.
IDSA @idsainfo.bsky.social calls for the resignation of RFK Jr. as "Health" Secretary.
Are there other organizations which will call for this?
www.idsociety.org/news--public...
Are there other organizations which will call for this?
www.idsociety.org/news--public...
Joint statement calling for Secretary Kennedy resignation
www.idsociety.org
September 4, 2025 at 12:36 AM
IDSA @idsainfo.bsky.social calls for the resignation of RFK Jr. as "Health" Secretary.
Are there other organizations which will call for this?
www.idsociety.org/news--public...
Are there other organizations which will call for this?
www.idsociety.org/news--public...
Reposted by Dr. David Boulware, MD MPH
#Metformin reduces risk on developing #PCC from 27,9% to 11.2% if started within 90 days of #SARS-COV-2 infection in #overweight/#obese patients in real-world settings (624 308 patients propensity-score)
Risk Difference At 1 y (%) -12,58%
Adjusted Hazard Ratio 0.36 academic.oup.com/cid/advance-...
Risk Difference At 1 y (%) -12,58%
Adjusted Hazard Ratio 0.36 academic.oup.com/cid/advance-...
Effect of Metformin on the Risk of Post-coronavirus Disease 2019 Condition Among Individuals With Overweight or Obese: A Population-based Retrospective Cohort Study
Early metformin treatment in overweight or obese adults with recent coronavirus disease 2019 infection significantly reduces the risk of developing post–co
academic.oup.com
September 2, 2025 at 6:57 AM
#Metformin reduces risk on developing #PCC from 27,9% to 11.2% if started within 90 days of #SARS-COV-2 infection in #overweight/#obese patients in real-world settings (624 308 patients propensity-score)
Risk Difference At 1 y (%) -12,58%
Adjusted Hazard Ratio 0.36 academic.oup.com/cid/advance-...
Risk Difference At 1 y (%) -12,58%
Adjusted Hazard Ratio 0.36 academic.oup.com/cid/advance-...
Why is OFID publishing a #covid study from 2021 reporting #paxlovid secondary trial results by Pfizer in high risk unvaccinated results - while burying the same results in the lower risk trial. @ofidjournal.bsky.social
Low risk results were presented at IDweek
academic.oup.com/ofid/article...
Low risk results were presented at IDweek
academic.oup.com/ofid/article...
Patient-Reported Outcomes of Nirmatrelvir Treatment for High-Risk, Nonhospitalized Adults With Symptomatic COVID-19
In a phase 2/3 trial, high-risk adults with confirmed symptomatic COVID-19 receiving nirmatrelvir/ritonavir twice daily for 5 days reported global impressi
academic.oup.com
September 2, 2025 at 12:25 PM
Why is OFID publishing a #covid study from 2021 reporting #paxlovid secondary trial results by Pfizer in high risk unvaccinated results - while burying the same results in the lower risk trial. @ofidjournal.bsky.social
Low risk results were presented at IDweek
academic.oup.com/ofid/article...
Low risk results were presented at IDweek
academic.oup.com/ofid/article...
America First? Not When It Comes to Your Health. www.nytimes.com/2025/08/24/o...
Money saved by impoundment. Opportunities lost. Video explains such opportunities to advance medical research to improve Anetjcan’s health
Money saved by impoundment. Opportunities lost. Video explains such opportunities to advance medical research to improve Anetjcan’s health
Opinion | America First? Not When It Comes to Your Health.
www.nytimes.com
August 25, 2025 at 4:16 AM
America First? Not When It Comes to Your Health. www.nytimes.com/2025/08/24/o...
Money saved by impoundment. Opportunities lost. Video explains such opportunities to advance medical research to improve Anetjcan’s health
Money saved by impoundment. Opportunities lost. Video explains such opportunities to advance medical research to improve Anetjcan’s health
Reposted by Dr. David Boulware, MD MPH
🎙️ Just published a new #Communicable episode: Communi...
Hosted by Angela Huttner @angelahuttner.bsky.social
Josh Nosanchuk @josh-nosanchuk.bsky.social
with invited guests:
Hatim Sati (@who.int)
Dimitrios Kontoyiannis (@mdanderson.bsky.social)
Listen here:
#IDSky #Clinmicro #MedSky
Hosted by Angela Huttner @angelahuttner.bsky.social
Josh Nosanchuk @josh-nosanchuk.bsky.social
with invited guests:
Hatim Sati (@who.int)
Dimitrios Kontoyiannis (@mdanderson.bsky.social)
Listen here:
#IDSky #Clinmicro #MedSky
Communicable E34: WHO's Fungal Priority Pathogens List
Fungal infections and disease have long been overlooked in terms of...
share.transistor.fm
August 24, 2025 at 10:00 PM
🎙️ Just published a new #Communicable episode: Communi...
Hosted by Angela Huttner @angelahuttner.bsky.social
Josh Nosanchuk @josh-nosanchuk.bsky.social
with invited guests:
Hatim Sati (@who.int)
Dimitrios Kontoyiannis (@mdanderson.bsky.social)
Listen here:
#IDSky #Clinmicro #MedSky
Hosted by Angela Huttner @angelahuttner.bsky.social
Josh Nosanchuk @josh-nosanchuk.bsky.social
with invited guests:
Hatim Sati (@who.int)
Dimitrios Kontoyiannis (@mdanderson.bsky.social)
Listen here:
#IDSky #Clinmicro #MedSky
Day 2 of Minnesota State Fair - the Great Minnesota Get Together.
Largest state fair in daily attendance. Today feels like a low 160,000 person day.
Largest state fair in daily attendance. Today feels like a low 160,000 person day.
August 22, 2025 at 10:05 PM
Day 2 of Minnesota State Fair - the Great Minnesota Get Together.
Largest state fair in daily attendance. Today feels like a low 160,000 person day.
Largest state fair in daily attendance. Today feels like a low 160,000 person day.
Fogarty International Clinical Research Fellowship: Seeking Applications
1 month away from the deadline for the July 2026- June 2027 fellowship year.
Opportunities in Global Health Research Training.
US applicants can come from any US institution.
For more info see:
fogartyfellows.org
1 month away from the deadline for the July 2026- June 2027 fellowship year.
Opportunities in Global Health Research Training.
US applicants can come from any US institution.
For more info see:
fogartyfellows.org
Global Health Fellows | Northern Pacific Global Health Research Fellows Training Consortium
fogartyfellows.org
August 15, 2025 at 8:52 PM
Fogarty International Clinical Research Fellowship: Seeking Applications
1 month away from the deadline for the July 2026- June 2027 fellowship year.
Opportunities in Global Health Research Training.
US applicants can come from any US institution.
For more info see:
fogartyfellows.org
1 month away from the deadline for the July 2026- June 2027 fellowship year.
Opportunities in Global Health Research Training.
US applicants can come from any US institution.
For more info see:
fogartyfellows.org
Reposted by Dr. David Boulware, MD MPH
VP shunts are key for CSF diversion in refractory coccidioidal meningitis. In a study of 124 patients, 17% had abdominal pseudocysts, often with shunt malfunction symptoms. 71% had active infection.##idsky
Trapped Below: Abdominal Pseudocysts Associated with Ventriculoperitoneal Shunts in Coccidioidal Meningitis
AbstractVentriculoperitoneal (VP) shunts are the mainstay for cerebrospinal fluid (CSF) diversion in patients with refractory coccidioidal meningitis (CM)-associated hydrocephalus. Abdominal pseudocysts (APCs), an uncommon but known complication of distal shunt catheters, have not been well described in CM. We conducted a retrospective study of 124 patients with CM who underwent VP shunt placement between 2010 and 2024. APCs occurred in 21 patients (17%), with most presenting with symptoms of shunt malfunction rather than abdominal complaints. This incidence is notably higher than previously reported in patients with hydrocephalus due to other etiologies. Evidence of active Coccidioides infection was present in 71% of patients. Imaging typically revealed fluid collections at the distal catheter tip, and most patients underwent surgical intervention targeting the distal shunt. Despite intervention, recurrent shunt failures occurred in a substantial proportion. These findings add to the limited literature on APCs in CM and may inform future research into their presentation, contributing factors, and management.
academic.oup.com
August 14, 2025 at 12:30 AM
VP shunts are key for CSF diversion in refractory coccidioidal meningitis. In a study of 124 patients, 17% had abdominal pseudocysts, often with shunt malfunction symptoms. 71% had active infection.##idsky
What is the correct dose of flucytosine in cryptococcal meningitis? 100mg/kg is a round number? Is it correct? We sought to test whether lower dose 60mg/kg x 10 days was equally effective. doi.org/10.1093/cid/...
Trial was designed by the great ID UMN fellow Tom McHale @umn-idim.bsky.social
Trial was designed by the great ID UMN fellow Tom McHale @umn-idim.bsky.social
August 8, 2025 at 9:51 PM
What is the correct dose of flucytosine in cryptococcal meningitis? 100mg/kg is a round number? Is it correct? We sought to test whether lower dose 60mg/kg x 10 days was equally effective. doi.org/10.1093/cid/...
Trial was designed by the great ID UMN fellow Tom McHale @umn-idim.bsky.social
Trial was designed by the great ID UMN fellow Tom McHale @umn-idim.bsky.social
Reposted by Dr. David Boulware, MD MPH
As end-of-empire scenarios go it is so much more dignified to get your capital city sacked by the Visigoths than to have a bunch of illiterate rich people in their 70s doing it through a series of incomprehensible tantrums because their brains were defeated by their phones.
August 5, 2025 at 11:44 PM
As end-of-empire scenarios go it is so much more dignified to get your capital city sacked by the Visigoths than to have a bunch of illiterate rich people in their 70s doing it through a series of incomprehensible tantrums because their brains were defeated by their phones.
Reposted by Dr. David Boulware, MD MPH
If you work in/adjacent to Democratic politics, or even if you are an occasional Democratic donor, this new @adambonica.bsky.social piece is the most important thing you can read today.
The Democratic Party cannot build power if it allows scam pacs to thrive
open.substack.com/pub/data4dem...
The Democratic Party cannot build power if it allows scam pacs to thrive
open.substack.com/pub/data4dem...
August 3, 2025 at 1:36 PM
If you work in/adjacent to Democratic politics, or even if you are an occasional Democratic donor, this new @adambonica.bsky.social piece is the most important thing you can read today.
The Democratic Party cannot build power if it allows scam pacs to thrive
open.substack.com/pub/data4dem...
The Democratic Party cannot build power if it allows scam pacs to thrive
open.substack.com/pub/data4dem...
Tesla dinner is open in LA
Inflatable Elon Musks doing a Nazi salute have been put up outside the Tesla diner in Hollywood
August 3, 2025 at 12:45 PM
Tesla dinner is open in LA