Fibo
@jfabriciolh.bsky.social
Full-time father, part-time postdoc at Thornton Lab at UChicago | Evolutionary genetics
Reposted by Fibo
I am looking to hire a postdoc interested in combining genetics and evolution to understand why telomeres vary so much in plants. My group has been developing Mimulus a genetic model for studying plant telomeres and we have really cool research brewing. Please check ad for detail. Deadline is 12/31.
November 16, 2025 at 8:29 PM
I am looking to hire a postdoc interested in combining genetics and evolution to understand why telomeres vary so much in plants. My group has been developing Mimulus a genetic model for studying plant telomeres and we have really cool research brewing. Please check ad for detail. Deadline is 12/31.
Reposted by Fibo
The full list of instructors is available here
bsky.app/profile/jlst...
bsky.app/profile/jlst...
November 10, 2025 at 7:28 PM
The full list of instructors is available here
bsky.app/profile/jlst...
bsky.app/profile/jlst...
Reposted by Fibo
One of the most exciting works of my career, years in the making. We used high-throughput precision genome editing to test the fitness effects of thousands of natural variants. Our findings challenge the long-held assumption that common variants are inconsequential.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Massively parallel interrogation of the fitness of natural variants in ancient signaling pathways reveals pervasive local adaptation
The nature of standing genetic variation remains a central debate in population genetics, with differing perspectives on whether common variants are almost always neutral as suggested by neutral and n...
www.biorxiv.org
October 22, 2025 at 5:46 PM
One of the most exciting works of my career, years in the making. We used high-throughput precision genome editing to test the fitness effects of thousands of natural variants. Our findings challenge the long-held assumption that common variants are inconsequential.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Fibo
Hey Yaniv Brandvain is not on Bluesky but his most recent biostats ebook is live ybrandvain.github.io/biostats/. His stats resources have been so helpful to me as I develop my own stats course, so check it out. Github repo here: github.com/ybrandvain/b...
Applied Biostatistics
ybrandvain.github.io
October 24, 2025 at 2:47 PM
Hey Yaniv Brandvain is not on Bluesky but his most recent biostats ebook is live ybrandvain.github.io/biostats/. His stats resources have been so helpful to me as I develop my own stats course, so check it out. Github repo here: github.com/ybrandvain/b...
Mi wife (an american) just taught me (a mexican) how to transform stale tortilla chips to fresh again using a mini oven. Nothing goes to waste in this house for sure.
September 26, 2025 at 6:28 PM
Mi wife (an american) just taught me (a mexican) how to transform stale tortilla chips to fresh again using a mini oven. Nothing goes to waste in this house for sure.
Reposted by Fibo
New preprint reveals bacteria can't just collect all resistance genes like Pokemon cards.
We found mutually exclusive evolutionary pathways to multidrug resistance in E. coli & P. aeruginosa - some resistance mechanisms actively prevent others from coexisting www.biorxiv.org/content/10.1...
We found mutually exclusive evolutionary pathways to multidrug resistance in E. coli & P. aeruginosa - some resistance mechanisms actively prevent others from coexisting www.biorxiv.org/content/10.1...
Genomic constraints shape the evolution of alternative routes to drug resistance in prokaryotes
Background Variation within the prokaryotic pangenome is not random, and natural selection that favours particular combinations of genes appears to dominate over random drift. What is less clear is wh...
www.biorxiv.org
August 29, 2025 at 2:05 PM
New preprint reveals bacteria can't just collect all resistance genes like Pokemon cards.
We found mutually exclusive evolutionary pathways to multidrug resistance in E. coli & P. aeruginosa - some resistance mechanisms actively prevent others from coexisting www.biorxiv.org/content/10.1...
We found mutually exclusive evolutionary pathways to multidrug resistance in E. coli & P. aeruginosa - some resistance mechanisms actively prevent others from coexisting www.biorxiv.org/content/10.1...
Reposted by Fibo
I cannot fully put into words what publishing this Review has meant to me, so I leave you with how we closed the paper.
"The humble bacterium is still a relevant tool for the study of the underlying mechanisms that are conserved throughout life."
🧪🧫🧬📚
doi.org/10.1093/gene...
"The humble bacterium is still a relevant tool for the study of the underlying mechanisms that are conserved throughout life."
🧪🧫🧬📚
doi.org/10.1093/gene...
The nature of mutation: a legacy of bacterial genetics
Abstract. A central question in the fields of genetics and evolution was the nature and origin of spontaneous mutation. Bacterial genetic experiments throu
doi.org
August 25, 2025 at 4:48 PM
I cannot fully put into words what publishing this Review has meant to me, so I leave you with how we closed the paper.
"The humble bacterium is still a relevant tool for the study of the underlying mechanisms that are conserved throughout life."
🧪🧫🧬📚
doi.org/10.1093/gene...
"The humble bacterium is still a relevant tool for the study of the underlying mechanisms that are conserved throughout life."
🧪🧫🧬📚
doi.org/10.1093/gene...
Reposted by Fibo
Me and my group are searching for a senior postdoc (3 +3 years) in the field of theoretical/ computational biology.
The position provides the opportunity to closely interact with experimentalists and develop own research projects.
Please RT.
Deadline: 11/09/2025
Details 👇:
shorturl.at/iiiOv
The position provides the opportunity to closely interact with experimentalists and develop own research projects.
Please RT.
Deadline: 11/09/2025
Details 👇:
shorturl.at/iiiOv
116 FB 5 Research Assistant (m/f/d) field of Theoretical Ecology and Evolution or Computational Biology: Uni Osnabrück
shorturl.at
August 18, 2025 at 5:35 AM
Me and my group are searching for a senior postdoc (3 +3 years) in the field of theoretical/ computational biology.
The position provides the opportunity to closely interact with experimentalists and develop own research projects.
Please RT.
Deadline: 11/09/2025
Details 👇:
shorturl.at/iiiOv
The position provides the opportunity to closely interact with experimentalists and develop own research projects.
Please RT.
Deadline: 11/09/2025
Details 👇:
shorturl.at/iiiOv
Reposted by Fibo
This preprint from Helen Sakharova is one of the coolest things to come out of my lab: “Protein language models reveal evolutionary constraints on synonymous codon choice.” Codon choice is a big puzzle in how information is encoded in genomes, and we have a new angle. www.biorxiv.org/content/10.1...
Protein language models reveal evolutionary constraints on synonymous codon choice
Evolution has shaped the genetic code, with subtle pressures leading to preferences for some synonymous codons over others. Codons are translated at different speeds by the ribosome, imposing constrai...
www.biorxiv.org
August 7, 2025 at 8:29 AM
This preprint from Helen Sakharova is one of the coolest things to come out of my lab: “Protein language models reveal evolutionary constraints on synonymous codon choice.” Codon choice is a big puzzle in how information is encoded in genomes, and we have a new angle. www.biorxiv.org/content/10.1...
Reposted by Fibo
I am opening scientific illustration commissions! Below are some examples of my work. Please contact me via bfitzwater@crimson.ua.edu if you are interested!
August 7, 2025 at 4:32 PM
I am opening scientific illustration commissions! Below are some examples of my work. Please contact me via bfitzwater@crimson.ua.edu if you are interested!
Reposted by Fibo
🚨 Attention early-career scientists! 🚨
Become a Theory Fellow at Janelia and use computation & theory to tackle biological problems.
✅ Three-year appointment
✅ Collaboration across scientific disciplines
✅ Dynamic research environment
Become a Theory Fellow at Janelia and use computation & theory to tackle biological problems.
✅ Three-year appointment
✅ Collaboration across scientific disciplines
✅ Dynamic research environment
August 5, 2025 at 2:49 PM
🚨 Attention early-career scientists! 🚨
Become a Theory Fellow at Janelia and use computation & theory to tackle biological problems.
✅ Three-year appointment
✅ Collaboration across scientific disciplines
✅ Dynamic research environment
Become a Theory Fellow at Janelia and use computation & theory to tackle biological problems.
✅ Three-year appointment
✅ Collaboration across scientific disciplines
✅ Dynamic research environment
Reposted by Fibo
Network, we are looking for PhD students and Postdocs on evolutionary and ecological genomics in 2025/2026
Join our diverse and welcoming lab at UC Berkeley & HHMINEWS!
Check job ads-> www.moilab.science/team/join-us
Join our diverse and welcoming lab at UC Berkeley & HHMINEWS!
Check job ads-> www.moilab.science/team/join-us
M O I L A B - Join us!
Join us!
Our lab is based at the University of California, Berkeley, embedded in the vibrant and multicultural San Francisco Bay Area, surrounded by astonishing nature!
www.moilab.science
July 22, 2025 at 10:32 PM
Network, we are looking for PhD students and Postdocs on evolutionary and ecological genomics in 2025/2026
Join our diverse and welcoming lab at UC Berkeley & HHMINEWS!
Check job ads-> www.moilab.science/team/join-us
Join our diverse and welcoming lab at UC Berkeley & HHMINEWS!
Check job ads-> www.moilab.science/team/join-us
Reposted by Fibo
Applications now open for the SSE GREG Rosemary Grant Advanced Awards! These grants provide up to $3500 to expand your dissertation work. Submit your proposal by September 15!
www.evolutionsociety.org/content/soci...
www.evolutionsociety.org/content/soci...
July 15, 2025 at 9:16 PM
Applications now open for the SSE GREG Rosemary Grant Advanced Awards! These grants provide up to $3500 to expand your dissertation work. Submit your proposal by September 15!
www.evolutionsociety.org/content/soci...
www.evolutionsociety.org/content/soci...
Reposted by Fibo
Experimental evolution in an era of molecular manipulation
#ExperimentalEvolution #evolution #evoSky
www.nature.com/articles/s41...
#ExperimentalEvolution #evolution #evoSky
www.nature.com/articles/s41...
Experimental evolution in an era of molecular manipulation - Nature Reviews Genetics
In this Review, Ascensao and Desai discuss how methodological advances in genotype and phenotype manipulation are transforming experimental evolution approaches and providing new insights into the und...
www.nature.com
July 21, 2025 at 9:02 PM
Experimental evolution in an era of molecular manipulation
#ExperimentalEvolution #evolution #evoSky
www.nature.com/articles/s41...
#ExperimentalEvolution #evolution #evoSky
www.nature.com/articles/s41...
Reposted by Fibo
In @elife.bsky.social: Effective population size does not explain long-term variation in genome size and transposable element content in animals doi.org/10.7554/eLif...
Effective population size does not explain long-term variation in genome size and transposable element content in animals
A large-scale survey across animals reveals no general association between genome size expansion and the relaxation of natural selection.
doi.org
July 19, 2025 at 5:50 AM
In @elife.bsky.social: Effective population size does not explain long-term variation in genome size and transposable element content in animals doi.org/10.7554/eLif...
Reposted by Fibo
Published in Nature today! Here, we sought to systematically ask how natural community's metabolism changes with the environment. A simple consumer-resource model can predict N-cycle metabolism (nitrate use) and, more importantly, the mechanism behind its change.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Functional regimes define soil microbiome response to environmental change - Nature
Experimental perturbation of soil pH leads to a generalizable model of the soil microcosm comprising three functional regimes with distinct mechanisms linking environmental change to metabolite dynami...
www.nature.com
July 16, 2025 at 3:19 PM
Published in Nature today! Here, we sought to systematically ask how natural community's metabolism changes with the environment. A simple consumer-resource model can predict N-cycle metabolism (nitrate use) and, more importantly, the mechanism behind its change.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Fibo
Please share! Our lab is recruiting a PhD student to join us starting fall 2026. Our group is broadly interested in plant molecular evolution and comparative genomics. More info about our lab and grad programs at Colorado St. is available on our lab website.
sites.google.com/site/danielb...
sites.google.com/site/danielb...
Sloan Lab
Welcome! Our research focuses on the evolutionary process at the molecular level. In particular, we investigate how a mixture of natural selection and non-adaptive forces create and maintain the amazi...
sites.google.com
July 14, 2025 at 7:35 PM
Please share! Our lab is recruiting a PhD student to join us starting fall 2026. Our group is broadly interested in plant molecular evolution and comparative genomics. More info about our lab and grad programs at Colorado St. is available on our lab website.
sites.google.com/site/danielb...
sites.google.com/site/danielb...
Reposted by Fibo
I'm recruiting a 2-yr postdoc to start in October or November of 2025! I'm looking for applicants interested in exploring amphibian disease ecology as it relates to climate change. Strong quantitative skills preferred, interviews start late July. More info: erinsauer.com
July 7, 2025 at 6:55 PM
I'm recruiting a 2-yr postdoc to start in October or November of 2025! I'm looking for applicants interested in exploring amphibian disease ecology as it relates to climate change. Strong quantitative skills preferred, interviews start late July. More info: erinsauer.com
Reposted by Fibo
The deadline for submissions to the special issue "Yeast in Microbiomes" has been extended to 15 October. We accept manuscripts exploring yeast diversity, interactions, and adaptations in diverse host environments. Hurry up and don't miss this opportunity!!!
onlinelibrary.wiley.com/page/journal...
onlinelibrary.wiley.com/page/journal...
Yeast Call for Papers: Yeast in Microbiomes
Yeast is a microbiology journal for research in the rapidly moving field of yeast biology. We publish the most significant developments in unicellular fungi.
onlinelibrary.wiley.com
July 7, 2025 at 4:16 PM
The deadline for submissions to the special issue "Yeast in Microbiomes" has been extended to 15 October. We accept manuscripts exploring yeast diversity, interactions, and adaptations in diverse host environments. Hurry up and don't miss this opportunity!!!
onlinelibrary.wiley.com/page/journal...
onlinelibrary.wiley.com/page/journal...
Reposted by Fibo
Words cannot describe how excited I am to share the findings from the second half of my postdoc in @aaronwhiteley.bsky.social's lab where we discover that bacteria use functional amyloids to defend themselves from predatory bacteria. rdcu.be/euu5Y. See thread for details on this epic adventure 1/.
Functional amyloid proteins confer defence against predatory bacteria
Nature - Escherichia coli uses curli fibres, oligomers of the functional amyloid CsgA, as a barrier to protect against the predatory bacteria Bdellovibrio bacteriovorus and Myxococcus xanthus in a...
rdcu.be
July 2, 2025 at 8:10 PM
Words cannot describe how excited I am to share the findings from the second half of my postdoc in @aaronwhiteley.bsky.social's lab where we discover that bacteria use functional amyloids to defend themselves from predatory bacteria. rdcu.be/euu5Y. See thread for details on this epic adventure 1/.
Reposted by Fibo
Reposted by Fibo
Now published in PNAS: www.pnas.org/doi/10.1073/...
May 23, 2025 at 6:39 PM
Now published in PNAS: www.pnas.org/doi/10.1073/...
Reposted by Fibo
#Fungal infections are hard to treat due to #DrugResistance. @blakebillmyre.bsky.social &co use a high-throughput #TNseq system in #Cryptococcus neoformans to identify >1400 essential genes & reveal a role for #mitochondrial genes in #fluconazole sensitivity @plosbiology.org 🧪 plos.io/4dz3iVm
May 24, 2025 at 9:44 AM
#Fungal infections are hard to treat due to #DrugResistance. @blakebillmyre.bsky.social &co use a high-throughput #TNseq system in #Cryptococcus neoformans to identify >1400 essential genes & reveal a role for #mitochondrial genes in #fluconazole sensitivity @plosbiology.org 🧪 plos.io/4dz3iVm
Reposted by Fibo
Congratulations to this year's Hamilton Award finalists! 🎉 Join us Thursday, May 29 to hear these outstanding student talks. See the full schedule on the meeting website: www.evolutionmeetings.org/program-over... @evolmtg.bsky.social
May 22, 2025 at 7:22 AM
Congratulations to this year's Hamilton Award finalists! 🎉 Join us Thursday, May 29 to hear these outstanding student talks. See the full schedule on the meeting website: www.evolutionmeetings.org/program-over... @evolmtg.bsky.social
Reposted by Fibo
10/n To relax this assumption, we take advantage of the progress in geometric deep learning. More specifically, we use a neural network called a "Riemannian Hamiltonian Variational Autoencoder" (RHVAE) that not only reduces dimensionality but preserves the geometric relationships between data points
May 15, 2025 at 2:33 PM
10/n To relax this assumption, we take advantage of the progress in geometric deep learning. More specifically, we use a neural network called a "Riemannian Hamiltonian Variational Autoencoder" (RHVAE) that not only reduces dimensionality but preserves the geometric relationships between data points