Mashaal Sohail
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mashaals.bsky.social
Mashaal Sohail
@mashaals.bsky.social
310 followers 550 following 18 posts
Evolutionary and statistical geneticist. Associate Professor at
Center for Genomic Sciences, UNAM.

http://sohaillab.com
UNAM | U Chicago | Langebio | Harvard | MIT
🇵🇰🇺🇸🇲🇽🏳️‍🌈
Posts Replies Media Videos
Reposted by Mashaal Sohail
fsanchezquinto.bsky.social
Lo logramos! @paleogenomics.bsky.social @vvillaislas.bsky.social @mashaals.bsky.social @jcchacond.bsky.social #EduardoArrieta #AngelesTavares #MiriamBravo, #AleCastillo #MarceSandoval, Muchas gracias por su gran entusiasmo, dedicación y entrega. (Ayúdenme a taggear a quienes hacen falta).
fsanchezquinto.bsky.social Federico Sánchez Quinto @fsanchezquinto.bsky.social · Aug 29
La historia de cómo secuenciamos los mamtus 🦣 más tropicales 🏝️ secuenciados al momento la pueden leer aquí 👇https://shorturl.at/KE6Ux. Redactadó por el gran @rpocisv.bsky.social. Muchas gracias Rodrigo por cubrir con tanto entusiasmo la nota sobre nuestro trabajo.
Mammoths in Mexico? Huge bone trove reveals giant beasts thrived in warmth, too
Fossils found while building airport contain first mammoth DNA from tropical location
shorturl.at
August 29, 2025 at 2:15 AM
Reposted by Mashaal Sohail
andganna.bsky.social
Leena Peltonen School of Human Genetics in full-swing!

@gosiatrynka.bsky.social
@dgmacarthur.bsky.social
@bpasaniuc.bsky.social
@tuuliel.bsky.social
@hilarycmartin.bsky.social
@sashagusevposts.bsky.social
@zkutalik.bsky.social
@mashaals.bsky.social
@alemedinarivera.bsky.social
July 30, 2025 at 10:04 AM
mashaals.bsky.social
Absolutely wonderful experience helping train HHMI bioambassadors to teach high school and college biology in non-deterministic frameworks and with a deep understanding of the multi-scale complexity of human genetic variation @biointeractive.bsky.social @hhmijanelia.bsky.social
July 11, 2025 at 6:22 AM
mashaals.bsky.social
Mi charla como parte del serie de charlas públicas sobre Genética humana y Paleogenómica

Genes entrelazados, historias compartidas
Intertwined genes, shared histories

www.youtube.com/watch?v=Naen...
Genes entrelazados, historias compartidas
YouTube video by elcolegionacionalmx
www.youtube.com
June 24, 2025 at 8:51 PM
mashaals.bsky.social
Full cycle of talks on Human Genetics and Paleogenomics is available on YouTube with El Colegio Nacional MX Fundación UNAM (some in English and some in Spanish) @sarahtishkoff.bsky.social @jnovembre.bsky.social @fsanchezquinto.bsky.social @gcbias.bsky.social and others!

youtube.com/playlist?lis...
Genómica Humana Y Paleogenómica // Human Genetics and Paleogenomics - YouTube
Since our origins we have wondered where we come from. The research on genomics, paleogenomics and the human genome are now providing answers on this questio...
youtube.com
June 24, 2025 at 8:49 PM
Reposted by Mashaal Sohail
delvecchyo.bsky.social
Happy to have worked on this project with @mashaals.bsky.social , Emilia Huerta-Sanchez and Valeria Añorve-Garibay. We analyzed how stabilizing and directional selection cause problems to predict traits in ancient samples.
mashaals.bsky.social Mashaal Sohail @mashaals.bsky.social · Jun 10
Our new work is now out in AJHG "Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples." Great collaboration with @delvecchyo.bsky.social and Emilia Huerta-Sanchez, led by Valeria Añorve-Garibay.
ajhgnews.bsky.social The American Journal of Human Genetics @ajhgnews.bsky.social · Jun 10
📣Online now!
📄Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples
🧑‍🤝‍🧑 @delvecchyo.bsky.social @mashaals.bsky.social & co
June 10, 2025 at 5:58 PM
mashaals.bsky.social
Our new work is now out in AJHG "Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples." Great collaboration with @delvecchyo.bsky.social and Emilia Huerta-Sanchez, led by Valeria Añorve-Garibay.
June 10, 2025 at 4:38 PM
mashaals.bsky.social
Subcontinental genetic variation in the All of Us Research Program: Implications for biomedical research
www.cell.com/ajhg/fulltex...
Subcontinental genetic variation in the All of Us Research Program: Implications for biomedical research
Analysis of 230,016 genomes in the All of Us Research Program revealed substantial variation in continental and subcontinental ancestry within self-reported race and ethnicity across the US. Subcontin...
www.cell.com
June 5, 2025 at 9:27 PM
Reposted by Mashaal Sohail
tkcaccia.bsky.social
KODAMA goes spatial.
doi.org/10.1101/2025...
#spatialtranscriptomics #visium #visiumhd #seurat #giotto
June 2, 2025 at 8:22 PM
mashaals.bsky.social
“Genes and geography: understanding human genetic variation” by @jnovembre.bsky.social, second talk in this cycle of talks on Human genomics and Paleogenomics for a general audience.
Tuesday 29th November 12pm Mexico City time/1pm central time/2pm est.

colnal.mx/agenda/genes...
April 23, 2025 at 8:50 PM
mashaals.bsky.social
African evolutionary genomics: reconstructing human evolution and the genetic basic of complex adaptive traits by @sarahtishkoff.bsky.social, Tuesday 22nd April 12pm Mexico City time.

colnal.mx/agenda/afric...
April 21, 2025 at 11:00 PM
mashaals.bsky.social
Honored to be mentioned for my contributions in human evolutionary genetics!

www.nature.com/articles/s41...
April 3, 2025 at 10:49 PM
mashaals.bsky.social
Register for the UPennn symposium on “Inclusive Genomics to Promote Health Excellence” organized by @sarahtishkoff.bsky.social and @bpasaniuc.bsky.social at the Center for Global Genomics & Health Equity and the Center for Computational Biomedicine.
Link: upenn.co1.qualtrics.com/jfe/form/SV_...
April 2, 2025 at 9:17 PM
Reposted by Mashaal Sohail
ajhgnews.bsky.social
📣New from Yang et al.
📄Fine-mapping in admixed populations using CARMA-X, with applications to Latin American studies
www.cell.com/ajhg/abstrac...
Fine-mapping in admixed populations using CARMA-X, with applications to Latin American studies
CARMA-X is a robust fine-mapping method for admixed populations, leveraging ancestry-specific data to identify putative causal variants. By modeling cross-ancestry correlations and accounting for LD v...
www.cell.com
March 26, 2025 at 4:37 PM
mashaals.bsky.social
Nice collaboration with Luliana Lonita-Laza's group at Columbia. "Fine-mapping in admixed populations using CARMA-X, with applications to Latin American studies" now out in
@ajhgnews.bsky.social
@scientist-ninja.bsky.social
authors.elsevier.com/c/1kqIJgeXDypv
www.cell.com/ajhg/fulltex...
Fine-mapping in admixed populations using CARMA-X, with applications to Latin American studies
CARMA-X is a robust fine-mapping method for admixed populations, leveraging ancestry-specific data to identify putative causal variants. By modeling cross-ancestry correlations and accounting for LD v...
www.cell.com
March 26, 2025 at 10:13 PM
mashaals.bsky.social
When in evolutionary time does accelerated genomic change occur across phenotypes? Our study out in Cell Genomics led by Eucharist Kun, with Vagheesh Narasimhan integrates comparative, functional, and ancient genomic data with GWAS. Read more www.cell.com/cell-genomic...
The trait-specific timing of accelerated genomic change in the human lineage
Kun et al. examine the timing of accelerated genomic changes in human evolution by linking human traits to genomic annotations related to distinct evolutionary points. Their findings reveal that skele...
www.cell.com
March 25, 2025 at 1:03 AM
mashaals.bsky.social
New perspective "Evolution, genetic diversity and health" led by PhD student @madmaxolotl.bsky.social and post-doc @scientist-ninja.bsky.social in @naturemedicine.bsky.social
nature.com/articles/s41...
PDF here: rdcu.be/eczeW
Evolution, genetic diversity, and health - Nature Medicine
This Perspective explains how past migrations and environmental exposures have influenced genomic diversity, and how understanding and contextualizing this diversity is crucial to advancing precision ...
nature.com
March 25, 2025 at 12:58 AM
Reposted by Mashaal Sohail
elagusdekomodo.bsky.social
Hoy nos la pasamos muy bien en Mutante, con @mashaals.bsky.social
February 25, 2025 at 2:09 AM
mashaals.bsky.social
Tracing human trait evolution through integrative genomics and temporal annotations, a preview of our recent study with Eucharist Kun and Vagheesh Narasimhan
www.cell.com/cell-genomic...
Tracing human trait evolution through integrative genomics and temporal annotations
Understanding the evolution of human traits is a fundamental yet challenging question. In a recent Cell Genomics article, Kun et al. integrate large-scale genomic and phenotypic data, including deep-l...
www.cell.com
January 27, 2025 at 11:17 PM
mashaals.bsky.social
🌟 Excited to teach at The Leena Peltonen School of Human Genetics in 2025!

This prestigious summer school brings together leaders in human genetics with PhD students

📅 July 27-31, 2025

📍 Wellcome Genome Campus, UK

📝 Apply by March 7 at www.lpshg.com
January 22, 2025 at 11:56 PM
mashaals.bsky.social
Excited to share our pre-print "The multi-scale complexity of human genetic variation beyond continental groups" biorxiv.org/cgi/content/...
Global Genomic Network Communities browser: sohail-lab.shinyapps.io/GG-NC/
Github: github.com/mariajpalma/...
See🧵by lead author @madmaxolotl.bsky.social
December 19, 2024 at 5:17 PM