Moi Expósito-Alonso (MOILAB)
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mexpositoalonso.bsky.social
Moi Expósito-Alonso (MOILAB)
@mexpositoalonso.bsky.social
Researching from mutations to climate change • Scientist and Asst. Professor at University of California Berkeley and Freeman Hrabowski Scholar at Howard Hughes Medical Institute • In 💚 with California flora
Our lab from @HHMINEWS & @UCBerkeley is looking for undergrads to come for an internship!
www.hhmi.org/programs/cec...
Summer Undergraduate Research Experience | HHMI
The Cech Fellows Program is a paid, nine-week summer research experience empowering the next generation of scientific leaders.
www.hhmi.org
November 20, 2025 at 1:59 AM
Reposted by Moi Expósito-Alonso (MOILAB)
The First Annual Virtual WALII Symposium: Exploring Life Without Water is ONE WEEK AWAY! 🗓️💧

Register now to join us on November, 18!
www.walii.science/virtual-symp...
November 11, 2025 at 7:37 PM
Reposted by Moi Expósito-Alonso (MOILAB)
The work is led by @weiweibio.bsky.social, a talented postdoc looking for faculty positions now and conceptualized both computational prediction and in lab validation. Computational implementation is a collaboration with Xing Wu, postdoc with @mexpositoalonso.bsky.social
Qs - contact us 💻🌱🧬
October 29, 2025 at 4:55 PM
Reposted by Moi Expósito-Alonso (MOILAB)
🚀 New preprint!
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
Natural variation in regulatory code revealed through Bayesian analysis of plant pan-genomes and pan-transcriptomes
Understanding the genetic code of cis-regulatory elements (CREs) is essential for engineering gene expression and modulating agronomic traits in crops. In plants, CREs underlying rapid evolution of ge...
biorxiv.org
October 29, 2025 at 4:47 PM
Reposted by Moi Expósito-Alonso (MOILAB)
Very proud to present our first paper from the Moi Lab Carnegie common garden! @mexpositoalonso.bsky.social
Synthetic experimental populations of Arabidopsis thaliana with differing genetic backgrounds planted in a 14-level precipitation alteration common garden.

Preprint: www.biorxiv.org/content/10.1...

🧵👇
October 22, 2025 at 8:56 PM
Reposted by Moi Expósito-Alonso (MOILAB)
In A. thaliana and other plant systems, local adaptation is stronger closer to the equatorial edge and load is highest farther from the equator, which highlights a critical vulnerability: under strong selection, these high mutation load and low local adaptation populations may be the most at risk.
October 22, 2025 at 8:54 PM
Reposted by Moi Expósito-Alonso (MOILAB)
We monitored these populations for 3 years, and found that population growth rate decreased as the treatments became more stressful. Further, "high risk" populations (either high load or low local adaptation scores) had a higher stochasticity for recovery after a single year of water stress.
October 22, 2025 at 8:54 PM
Reposted by Moi Expósito-Alonso (MOILAB)
Crucially, we found a significant interaction between load and local adaptation, which grew stronger as the environment became more stressful. This suggests a synergistic decay of fitness resulting from locally adaptive variants, globally maladaptive load, and high water stress environments.
October 22, 2025 at 8:54 PM
Reposted by Moi Expósito-Alonso (MOILAB)
We found that populations with a low number of local adaptation alleles or high mutation load had decreased fitness in our highest drought stress environments.
October 22, 2025 at 8:54 PM
Reposted by Moi Expósito-Alonso (MOILAB)
By using data from other A. thaliana common gardens and genomic prediction tools, we created synthetic experimental populations of A. thaliana that varied in their abundance of locally adaptive alleles and also in their mutational load.
October 22, 2025 at 8:54 PM
Reposted by Moi Expósito-Alonso (MOILAB)
Synthetic experimental populations of Arabidopsis thaliana with differing genetic backgrounds planted in a 14-level precipitation alteration common garden.

Preprint: www.biorxiv.org/content/10.1...

🧵👇
October 22, 2025 at 8:54 PM
🚨🧬Next Generation Sequencing scientist position!

Shorter link for easier access!
tinyurl.com/SRA-81640

🙏Appreciate the sharing!

@ucberkeleyofficial.bsky.social
@hhmi.org
October 16, 2025 at 1:38 AM
Reposted by Moi Expósito-Alonso (MOILAB)
Apply for our PhD program on Evolution Ecology Organismal Biology (Integrative! Biology)

Dec 1 2025 deadline

Check out the Flyer below for more information on our #MOILAB!

Link to Flyer
docs.google.com/document/d/1...

@ucberkeleyofficial.bsky.social
@hhmi.org
October 13, 2025 at 8:08 PM
Apply for our PhD program on Evolution Ecology Organismal Biology (Integrative! Biology)

Dec 1 2025 deadline

Check out the Flyer below for more information on our #MOILAB!

Link to Flyer
docs.google.com/document/d/1...

@ucberkeleyofficial.bsky.social
@hhmi.org
October 13, 2025 at 8:08 PM
We are searching for a technician in Next Generation Sequencing!

Come to our lab University of California, Berkeley Howard Hughes Medical Institute (HHMI)

See ad:

careerspub.universityofcalifornia.edu/psp/ucb/EMPL...
An error has occurred.
careerspub.universityofcalifornia.edu
October 13, 2025 at 7:27 PM
Wed Oct 8 10am-11am PST FREE!
October 7, 2025 at 4:18 PM
Join a virtual information session on our PhD program at University of California, Berkeley on Evolution, Ecology, Organismal (Integrative!) Biology

ib.berkeley.edu/grad/admissi...

Check out our website for opportunities to join our lab as a PhD

www.moilab.science/team/join-us
Admissions
Can you see yourself at Berkeley? Attend the Graduate Diversity Admissions Fair Register here to attend our Integrative Biology PhD Program Info Session at the UC Berkeley Graduate Diversity Admission...
ib.berkeley.edu
October 7, 2025 at 4:16 PM
@Blueskyverse!

if you are interested in **plants and how they may live without water** join this fantastic virtual symposium organized by our NSF WATER AND LIFE INTERFACE INSTITUTE BII

- is free, and fun ;)

REGISTER HERE 👇
www.walii.science/virtual-symp...
September 24, 2025 at 11:20 PM
Excited to join this exciting webinar in November and introduce my past PhD advisor Detlef Weigel, long term mentor and dear colleague, so deserving of the award!

Congrats also to the wonderful co-recipients!
Please share & RSVP to join the November 25th webinar!
Hear from the 2025 Philip N. Benfey Arabidopsis Community Lifetime Achievement Awardees! bit.ly/naascawards
@plantevolution.bsky.social
September 24, 2025 at 11:16 PM
Reposted by Moi Expósito-Alonso (MOILAB)
Please share & RSVP to join the November 25th webinar!
Hear from the 2025 Philip N. Benfey Arabidopsis Community Lifetime Achievement Awardees! bit.ly/naascawards
@plantevolution.bsky.social
September 22, 2025 at 10:03 PM
Reposted by Moi Expósito-Alonso (MOILAB)
I'm making a collage of Arabidopsis habitats for a seminar. If you have photos to share, such as these iconic ones from @mexpositoalonso.bsky.social & @coevolution.bsky.social, please send to weigel@tue.mpg.de. Please let me also know how to attribute them. 🙏🙏🙏🙏
September 14, 2025 at 9:52 AM
August 22, 2025 at 10:12 PM
Reposted by Moi Expósito-Alonso (MOILAB)
*ALERT! GLOBAL GENETIC DIVERSITY TREND RE-ANALYSIS*

"Signals of consistent genetic diversity decline are not yet measurable in global meta-analysis" doi.org/10.1101/2025...
August 4, 2025 at 6:35 PM