Jae Young Choi
jychoi.bsky.social
Jae Young Choi
@jychoi.bsky.social
Assistant professor of evolutionary genomics at KU. Has a toddler 🙂🙃🙂🙃🇰🇷🇨🇦🇺🇲
https://jychoilab.github.io/
I am looking to hire a postdoc interested in combining genetics and evolution to understand why telomeres vary so much in plants. My group has been developing Mimulus a genetic model for studying plant telomeres and we have really cool research brewing. Please check ad for detail. Deadline is 12/31.
November 16, 2025 at 8:29 PM
Reposted by Jae Young Choi
A nice write-up on the latest paper from my lab: news.ku.edu/news/article...

More commentary to come!

#PlantBiology #Drought #Corn #Maize #Microbiome #PlantScience #SoilHealth #PlantHealth
New study explores ‘legacy effects’ of soil microbes on plants across Kansas
Click for more on research in Nature Microbiology
news.ku.edu
November 8, 2025 at 1:54 AM
Excited to share a new method developed from my group thats published at Genome Biology. This was an amazing effort by my grad student Linh @linhngk.bsky.social. We developed Topsicle, a method that analyzes long read data for telomere analysis and length measuring.
doi.org/10.1186/s130...
Topsicle: a method for estimating telomere length from whole genome long-read sequencing data - Genome Biology
Telomeres protect chromosome ends and their length varies significantly between organisms. Because telomere length variation is associated with various biomedical and eco-evolutionary phenotypes, many...
doi.org
September 22, 2025 at 2:18 PM
Reposted by Jae Young Choi
Our latest paper is out: rdcu.be/ev6Ym — one of my favorite projects. It began about 8 years ago when Nobel laureate Torsten Wiesel asked me: what transcription factors regulate new genes? I had no idea then. Now we have some answers.
Gene regulatory networks and essential transcription factors for de novo-originated genes
Nature Ecology & Evolution - A combination of computational methods applied to single-cell RNA sequencing data and genetic experiments shows that a small number of transcription factors are...
rdcu.be
July 15, 2025 at 2:27 PM
I'm very excited to share a new method my grad student @linhngk.bsky.social and I have developed. Here's Topsicle a new computational method for analyzing long read sequencing data and estimate telomere length. Please see our preprint or this thread for detail!
www.biorxiv.org/content/10.1...
Topsicle: a method for estimating telomere length from whole genome long-read sequencing data
Telomeres protect chromosome ends and its length varies significantly between organisms. Because telomere length variation is associated with various biomedical and eco-evolutionary phenotypes, many b...
www.biorxiv.org
July 15, 2025 at 2:14 PM
I'd like to share a new method my grad student Linh and I have been developing called Topsicle. Do you have long read sequencing data and wondered what the telomere length of your organism is? If you're wondering then Topsicle is the tool for you!
github.com/jaeyoungchoi...
GitHub - jaeyoungchoilab/Topsicle: Topsicle utilizes abundance of telomere pattern k-mers to estimate telomere length in long read.
Topsicle utilizes abundance of telomere pattern k-mers to estimate telomere length in long read. - jaeyoungchoilab/Topsicle
github.com
June 28, 2025 at 5:54 PM
My group is at #Evol2025 to present everything about telomere evolution!

Surbhi Sat 11:15 will present Mimulus telomere molecular evolution

Linh Sat 12:00 will present Mimulus pangenome and telomeres

Joyce Sat poster board A7 is here as Undergraduate Diversity at Evolution

Please join us!
June 19, 2025 at 7:47 PM
I'm very excited to share the first research paper from my lab! My postdoc Surbhi led this amazing study. We combined genomics, evolution, and biochemistry to explain how telomeres evolved in monkeyflowers. If you're into unusual chromosome evolution please read! @plos.org
tinyurl.com/bdeku44x
Monkeyflower (Mimulus) uncovers the evolutionary basis of the eukaryote telomere sequence variation
Author summary One of the most fascinating phenomena in evolutionary biology is the rapid evolution of molecular complexes with conserved functions across the tree of life. Studying these complexes ha...
journals.plos.org
June 17, 2025 at 11:37 AM
Reposted by Jae Young Choi
I am excited to announce that registration and abstract submission is now open for Forest Genetics 2025 – ‘Harnessing Genetic Diversity for Resilient Forests’. Join us in State College, Pennsylvania from June 23-27, 2025 - all are welcome! forestgeneticsconference2025.com #forestgenetics2025
December 11, 2024 at 3:38 PM
Are you interested in a postdoc with both research and teaching? Please consider the NIH IRACDA fellowship at KU iracda.ku.edu. If interested I can sponsor especially if you're a plant biologist or evo biologist. Eligibility is limited to US citizen or PR. Please share!
August 1, 2024 at 2:10 PM
My lab is looking for a postdoctoral scholar. See image or t.co/bdIxT8eE6n
If you're a plant geneticist or mol biologist and appreciate the wonders of evolution this is a position for you.
We can teach dry lab or genomics so plz consider if you want to learn a new skill!
July 14, 2024 at 11:47 PM