Molly Przeworski
@mollyprz.bsky.social
Population & Human Genetics
Pinned
Registration for the 2026 NY Area Population Genetics meeting is now open, at events.simonsfoundation.org/e0mEoL?rt=8k.... Registration is free but required; if you are submitting an abstract, note that the deadline is *January 30th*.
Reposted by Molly Przeworski
“Success in US science has come from sustained funding and welcoming the best talent from around the world, yet both of these advantages are in decline”
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
China turns the tables in biotech
For at least a century, major scientific research initiatives have reliably occurred in the United States, usually in response to geopolitical competition. This helped establish the country’s status a...
www.science.org
February 11, 2026 at 12:03 PM
“Success in US science has come from sustained funding and welcoming the best talent from around the world, yet both of these advantages are in decline”
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Molly Przeworski
NEW: The FDA just shot down Moderna's new flu shot. From me:
www.theguardian.com/us-news/2026...
www.theguardian.com/us-news/2026...
FDA declines to review Moderna application for new flu vaccine
Moderna requests meeting to discuss refusal as decision could have implications for all new and updated vaccines
www.theguardian.com
February 10, 2026 at 11:52 PM
NEW: The FDA just shot down Moderna's new flu shot. From me:
www.theguardian.com/us-news/2026...
www.theguardian.com/us-news/2026...
Reposted by Molly Przeworski
“I am shocked and appalled,” one NCI scientist said. “We are moving funds away from so much promising research in order to do a preclinical study based on nonscientific ideas. It’s absurd.”
Holy shit—a terrible waste of $$
Bhattacharya is so kooky
“If lots of people believe it & it’s moving public health, we as NIH have an obligation, again, to treat it seriously,” Bhattacharya said at a MAHA event
Great reporting by @rachanadpradhan.bsky.social
kffhealthnews.org/news/article...
Bhattacharya is so kooky
“If lots of people believe it & it’s moving public health, we as NIH have an obligation, again, to treat it seriously,” Bhattacharya said at a MAHA event
Great reporting by @rachanadpradhan.bsky.social
kffhealthnews.org/news/article...
US Cancer Institute Studying Ivermectin’s ‘Ability To Kill Cancer Cells’ - KFF Health News
At a January event organized by allies of health secretary Robert F. Kennedy Jr., National Cancer Institute Director Anthony Letai said results may be released “in a few months.” Ivermectin, used to d...
kffhealthnews.org
February 10, 2026 at 2:16 PM
“I am shocked and appalled,” one NCI scientist said. “We are moving funds away from so much promising research in order to do a preclinical study based on nonscientific ideas. It’s absurd.”
Reposted by Molly Przeworski
The IICD will host a half-day symposium on Artificial Intelligence and Cancer Research on March 16, 2026. The program will feature short presentations from leading researchers and a keynote by @danapeer.bsky.social
(@mskcancercenter.bsky.social).
Free with registration: bit.ly/IICDSymposiu...
(@mskcancercenter.bsky.social).
Free with registration: bit.ly/IICDSymposiu...
February 9, 2026 at 2:31 PM
The IICD will host a half-day symposium on Artificial Intelligence and Cancer Research on March 16, 2026. The program will feature short presentations from leading researchers and a keynote by @danapeer.bsky.social
(@mskcancercenter.bsky.social).
Free with registration: bit.ly/IICDSymposiu...
(@mskcancercenter.bsky.social).
Free with registration: bit.ly/IICDSymposiu...
Reposted by Molly Przeworski
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
October 15, 2025 at 3:53 PM
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
Reposted by Molly Przeworski
Heritability = a statistical description of sources of interindividual variation in a specific set of people under a specific set of environmental conditions. It doesn't index a fixed underlying feature of human biology. A few lines in this paper acknowledge that but its overall framing may mislead.
Heritability of intrinsic human life span is about 50% when confounding factors are addressed
How heritable is human life span? If genetic heritability is high, longevity genes can reveal aging mechanisms and inform medicine and public health. However, current estimates of heritability are low...
www.science.org
January 30, 2026 at 3:36 PM
Heritability = a statistical description of sources of interindividual variation in a specific set of people under a specific set of environmental conditions. It doesn't index a fixed underlying feature of human biology. A few lines in this paper acknowledge that but its overall framing may mislead.
Reposted by Molly Przeworski
Join us at the Evolutionary Biology Centre at Uppsala University. We’re searching for an Assistant Professor in Biology. www.uu.se/en/about-uu/...
January 28, 2026 at 8:28 PM
Join us at the Evolutionary Biology Centre at Uppsala University. We’re searching for an Assistant Professor in Biology. www.uu.se/en/about-uu/...
Reposted by Molly Przeworski
Registration for the 2026 NY Area Population Genetics meeting is now open, at events.simonsfoundation.org/e0mEoL?rt=8k.... Registration is free but required; if you are submitting an abstract, note that the deadline is *January 30th*.
January 14, 2026 at 9:37 PM
Registration for the 2026 NY Area Population Genetics meeting is now open, at events.simonsfoundation.org/e0mEoL?rt=8k.... Registration is free but required; if you are submitting an abstract, note that the deadline is *January 30th*.
Reposted by Molly Przeworski
The US government lost more than 10,000 STEM PhDs last year, according to an analysis by Science of newly released OPM data, with 11 departures for every hire. And many OPM calls "voluntary" separations were probably pushed. www.science.org/content/arti...
U.S. government has lost more than 10,000 STEM Ph.D.s since Trump took office
A Science analysis reveals how many were fired, retired, or quit across 14 agencies
www.science.org
January 27, 2026 at 1:28 AM
The US government lost more than 10,000 STEM PhDs last year, according to an analysis by Science of newly released OPM data, with 11 departures for every hire. And many OPM calls "voluntary" separations were probably pushed. www.science.org/content/arti...
Reposted by Molly Przeworski
Moderna have announced that they won't run new phase three trials now with massive impacts for new vaccine development- why- its because of RFK Jr and his anti-vaccine campaigns and cancelling mRNA vaccine research which affect the sales the company can then make 🧪🧵 #PublicHealth
Moderna Won’t Run Phase III Vaccine Trials as Skepticism Grows in US: Bloomberg
Growing opposition to vaccines in the U.S., driven by recent government policy changes, makes it difficult to see a return on investment in vaccine development, Moderna CEO Stéphane Bancel said this w...
www.biospace.com
January 27, 2026 at 8:50 AM
Moderna have announced that they won't run new phase three trials now with massive impacts for new vaccine development- why- its because of RFK Jr and his anti-vaccine campaigns and cancelling mRNA vaccine research which affect the sales the company can then make 🧪🧵 #PublicHealth
Reposted by Molly Przeworski
🚨 New from me: Grant review at more than half of NIH's institutes could be frozen by the end of the year.
That's because crucial NIH grant-review panels are slated to be empty at those institutes by Jan 2027.
A wonky bureaucratic problem with big implications.
A short 🧵
That's because crucial NIH grant-review panels are slated to be empty at those institutes by Jan 2027.
A wonky bureaucratic problem with big implications.
A short 🧵
Exclusive: key NIH review panels due to lose all members by the end of 2026
Thirteen of the agency’s advisory councils, which must review grant applications before funding is awarded, are on track to have no voting members.
www.nature.com
January 22, 2026 at 7:46 PM
🚨 New from me: Grant review at more than half of NIH's institutes could be frozen by the end of the year.
That's because crucial NIH grant-review panels are slated to be empty at those institutes by Jan 2027.
A wonky bureaucratic problem with big implications.
A short 🧵
That's because crucial NIH grant-review panels are slated to be empty at those institutes by Jan 2027.
A wonky bureaucratic problem with big implications.
A short 🧵
Reposted by Molly Przeworski
Pregnancy loss is common in humans, and chromosomal abnormalities are the leading cause. Using genetic data from ~140,000 IVF embryos, we show that maternal variation in meiosis genes influences recombination and aneuploidy risk.
First authors: @saracarioscia.bsky.social & @aabiddanda.github.io
First authors: @saracarioscia.bsky.social & @aabiddanda.github.io
Common variation in meiosis genes shapes human recombination and aneuploidy - Nature
Analysis of data from pre-implantation genetic testing sheds light on the genetic basis of meiotic-origin aneuploidy, the leading cause of human pregnancy loss, identifying common genetic variants ass...
www.nature.com
January 21, 2026 at 9:14 PM
Pregnancy loss is common in humans, and chromosomal abnormalities are the leading cause. Using genetic data from ~140,000 IVF embryos, we show that maternal variation in meiosis genes influences recombination and aneuploidy risk.
First authors: @saracarioscia.bsky.social & @aabiddanda.github.io
First authors: @saracarioscia.bsky.social & @aabiddanda.github.io
Reposted by Molly Przeworski
🔬 Call to create junior research groups at the Institut Pasteur
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research
The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...
research.pasteur.fr
December 8, 2025 at 8:53 AM
🔬 Call to create junior research groups at the Institut Pasteur
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Reposted by Molly Przeworski
Job alert! Assistant professor position in the Department of Molecular Genetics (University of Toronto). Amazing department and city. jobs.utoronto.ca/job/Toronto-... Please share.
Assistant Professor - Virology
Assistant Professor - Virology
jobs.utoronto.ca
January 15, 2026 at 8:04 PM
Job alert! Assistant professor position in the Department of Molecular Genetics (University of Toronto). Amazing department and city. jobs.utoronto.ca/job/Toronto-... Please share.
Registration for the 2026 NY Area Population Genetics meeting is now open, at events.simonsfoundation.org/e0mEoL?rt=8k.... Registration is free but required; if you are submitting an abstract, note that the deadline is *January 30th*.
January 14, 2026 at 9:37 PM
Registration for the 2026 NY Area Population Genetics meeting is now open, at events.simonsfoundation.org/e0mEoL?rt=8k.... Registration is free but required; if you are submitting an abstract, note that the deadline is *January 30th*.
Reposted by Molly Przeworski
I am looking for a postdoc to develop high-performance algorithms in computational genomics. Email or DM me if interested. For more information, see hlilab.github.io/vacancies. RTs appreciated!
HLi Lab - Vacancies
Openings
hlilab.github.io
January 14, 2026 at 3:44 PM
I am looking for a postdoc to develop high-performance algorithms in computational genomics. Email or DM me if interested. For more information, see hlilab.github.io/vacancies. RTs appreciated!
Reposted by Molly Przeworski
We're recruiting for an Associate Professor of Statistics in the Department of Statistics, University of Oxford, in association with Jesus College.
⏰ One week left to apply – applications close Monday 19 January 2026.
➡️ Details and application information: tinyurl.com/59tjt7m2
⏰ One week left to apply – applications close Monday 19 January 2026.
➡️ Details and application information: tinyurl.com/59tjt7m2
January 12, 2026 at 2:50 PM
We're recruiting for an Associate Professor of Statistics in the Department of Statistics, University of Oxford, in association with Jesus College.
⏰ One week left to apply – applications close Monday 19 January 2026.
➡️ Details and application information: tinyurl.com/59tjt7m2
⏰ One week left to apply – applications close Monday 19 January 2026.
➡️ Details and application information: tinyurl.com/59tjt7m2
Reposted by Molly Przeworski
HAPPENING NOW: Tens of thousands have filled 5th Avenue in Manhattan on Sunday (Jan 11) in a massive anti-ICE protest.
New York showed up!
👏👏
(🎥Hands Off NYC)
New York showed up!
👏👏
(🎥Hands Off NYC)
January 11, 2026 at 7:39 PM
HAPPENING NOW: Tens of thousands have filled 5th Avenue in Manhattan on Sunday (Jan 11) in a massive anti-ICE protest.
New York showed up!
👏👏
(🎥Hands Off NYC)
New York showed up!
👏👏
(🎥Hands Off NYC)
Reposted by Molly Przeworski
Want to study the genomics of repeated adaptation with data from hundreds of species? New funding for non-Canadians @ grad or postdoc level. Internal competition at UCalgary with very short deadline so please get in touch ASAP!!
sshrc-crsh.canada.ca/en/funding/o...
sshrc-crsh.canada.ca/en/funding/o...
January 9, 2026 at 6:41 PM
Want to study the genomics of repeated adaptation with data from hundreds of species? New funding for non-Canadians @ grad or postdoc level. Internal competition at UCalgary with very short deadline so please get in touch ASAP!!
sshrc-crsh.canada.ca/en/funding/o...
sshrc-crsh.canada.ca/en/funding/o...
Reposted by Molly Przeworski
Muller’s ratchet but for an entire society, in real time.
January 9, 2026 at 9:40 PM
Muller’s ratchet but for an entire society, in real time.
Reposted by Molly Przeworski
Job AD. Research Directions:
1. Selection in early development; Pop gen methods applied to new technologies, i.e. scDNA-seq with D. Shao
2. Study of hypermutability and selection using population cohorts with E. Koch
3. Evolution of Mutagenesis with M. Penenell & @jgschraiber.bsky.social
1. Selection in early development; Pop gen methods applied to new technologies, i.e. scDNA-seq with D. Shao
2. Study of hypermutability and selection using population cohorts with E. Koch
3. Evolution of Mutagenesis with M. Penenell & @jgschraiber.bsky.social
POSTDOCTORAL RESEARCHER - McDermott Center HG&D - Seplyarskiy Lab
Discover POSTDOCTORAL RESEARCHER - McDermott Center HG&D - Seplyarskiy Lab and other PostDoc jobs in Dallas, TX and apply online today!
jobs.utsouthwestern.edu
December 8, 2025 at 5:31 PM
Job AD. Research Directions:
1. Selection in early development; Pop gen methods applied to new technologies, i.e. scDNA-seq with D. Shao
2. Study of hypermutability and selection using population cohorts with E. Koch
3. Evolution of Mutagenesis with M. Penenell & @jgschraiber.bsky.social
1. Selection in early development; Pop gen methods applied to new technologies, i.e. scDNA-seq with D. Shao
2. Study of hypermutability and selection using population cohorts with E. Koch
3. Evolution of Mutagenesis with M. Penenell & @jgschraiber.bsky.social
Reposted by Molly Przeworski
From an email to one of our faculty members....
Not even Plato can escape censorship at Texas A&M!
Not even Plato can escape censorship at Texas A&M!
January 6, 2026 at 8:15 PM
From an email to one of our faculty members....
Not even Plato can escape censorship at Texas A&M!
Not even Plato can escape censorship at Texas A&M!
Reposted by Molly Przeworski
I’m very excited to share our new preprint with @arbelharpak.bsky.social! We meta-analyze male-female allele frequency divergences across studies (gnomAD, UKB, AoU) and ask what drives the observed differences. (1/12)
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
January 7, 2026 at 9:33 PM
I’m very excited to share our new preprint with @arbelharpak.bsky.social! We meta-analyze male-female allele frequency divergences across studies (gnomAD, UKB, AoU) and ask what drives the observed differences. (1/12)
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Molly Przeworski
New preprint alert: we use sign errors as a test of how well TWAS works.
Very worryingly we find that TWAS gets the sign wrong around 1/3 of the time (compared to 50% for pure guessing). You can read more about our analysis here, and what we think is going on 👇
Very worryingly we find that TWAS gets the sign wrong around 1/3 of the time (compared to 50% for pure guessing). You can read more about our analysis here, and what we think is going on 👇
How well does TWAS estimate a gene’s direction of effect on a trait? We think of this as an important stress-test for the accuracy of TWAS.
In a new pre-print, we find that TWAS gets the sign wrong around 20-30% of the time!
doi.org/10.64898/202...
1/n
In a new pre-print, we find that TWAS gets the sign wrong around 20-30% of the time!
doi.org/10.64898/202...
1/n
High false sign rates in transcriptome-wide association studies
Transcriptome-wide association studies (TWAS) are widely used to identify genes involved in complex traits and to infer the direction of gene effects on traits. However, despite their popularity, it r...
doi.org
January 6, 2026 at 2:48 AM
New preprint alert: we use sign errors as a test of how well TWAS works.
Very worryingly we find that TWAS gets the sign wrong around 1/3 of the time (compared to 50% for pure guessing). You can read more about our analysis here, and what we think is going on 👇
Very worryingly we find that TWAS gets the sign wrong around 1/3 of the time (compared to 50% for pure guessing). You can read more about our analysis here, and what we think is going on 👇
Reposted by Molly Przeworski
I'm just delighted to announce our new preprint on genome-scale perturb-seq in CD4+ T cells. We learned both general lessons about the power of perturb-seq, and specific lessons about T cell biology.
Led by amazing postdocs Emma Dann and Ronghui Zhu, with my wonderful collaborator Alex Marson.
Led by amazing postdocs Emma Dann and Ronghui Zhu, with my wonderful collaborator Alex Marson.
Together with @ronghuizhu.bsky.social, we are thrilled to present our new perturb-seq study of 22M primary CD4+ T cells, across donors and timepoints – the result of a decade-long collaboration between the Marson @marsonlab.bsky.social and Pritchard @jkpritch.bsky.social labs 🧵 tinyurl.com/gwt2025
Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits
Gene regulatory networks encode the fundamental logic of cellular functions, but systematic network mapping remains challenging, especially in cell states relevant to human biology and disease. Here, ...
tinyurl.com
January 5, 2026 at 7:27 PM
I'm just delighted to announce our new preprint on genome-scale perturb-seq in CD4+ T cells. We learned both general lessons about the power of perturb-seq, and specific lessons about T cell biology.
Led by amazing postdocs Emma Dann and Ronghui Zhu, with my wonderful collaborator Alex Marson.
Led by amazing postdocs Emma Dann and Ronghui Zhu, with my wonderful collaborator Alex Marson.