Molly Przeworski
@mollyprz.bsky.social
Population & Human Genetics
Pinned
Collateral mutagenesis funnels multiple sources of DNA damage into a ubiquitous mutational signature
Mutations reflect the net effects of myriad types of damage, replication errors, and repair mechanisms, and thus are expected to differ across cell types with distinct exposures to mutagens, division ...
www.biorxiv.org
In these dark times, it comes as a rare pleasure to highlight @natanaels.bsky.social & @marcdemanuel.bsky.social's work on germline and somatic mutations in humans. 1/n
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
Reposted by Molly Przeworski
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
November 10, 2025 at 1:26 PM
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Reposted by Molly Przeworski
Very excited for our paper in @nature.com on what genes association studies discover and why. It was a privilege to work closely with @jeffspence.github.io, @jkpritch.bsky.social, and our collaborators.
How do GWAS and rare variant burden tests rank gene signals?
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
Specificity, length and luck drive gene rankings in association studies - Nature
Genetic association tests prioritize candidate genes based on different criteria.
www.nature.com
November 7, 2025 at 6:33 PM
Very excited for our paper in @nature.com on what genes association studies discover and why. It was a privilege to work closely with @jeffspence.github.io, @jkpritch.bsky.social, and our collaborators.
Reposted by Molly Przeworski
How do GWAS and rare variant burden tests rank gene signals?
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
Specificity, length and luck drive gene rankings in association studies - Nature
Genetic association tests prioritize candidate genes based on different criteria.
www.nature.com
November 7, 2025 at 12:05 AM
How do GWAS and rare variant burden tests rank gene signals?
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
Reposted by Molly Przeworski
📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Genome Biology. We are particularly interested in researchers investigating the molecular and biophysical mechanisms underlying genome function and regulation. More details ➡️ tinyurl.com/3t7vvdct
November 5, 2025 at 10:59 AM
📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Genome Biology. We are particularly interested in researchers investigating the molecular and biophysical mechanisms underlying genome function and regulation. More details ➡️ tinyurl.com/3t7vvdct
Reposted by Molly Przeworski
The exciting next instalment of Mutations in Time and Space... Open for registration now
Explore the origins, patterns and consequences of mutations across biological systems! #MITS26
🗓️ Conference dates: 13-15 April 2026
Participate in expert-led knowledge exchange on how genome evolution shapes human health and ageing 🧬
Check out our exciting speakers ➡️ bit.ly/4hmbnyr
#Genomics
🗓️ Conference dates: 13-15 April 2026
Participate in expert-led knowledge exchange on how genome evolution shapes human health and ageing 🧬
Check out our exciting speakers ➡️ bit.ly/4hmbnyr
#Genomics
November 4, 2025 at 10:28 AM
The exciting next instalment of Mutations in Time and Space... Open for registration now
Reposted by Molly Przeworski
We have TWO post-doctoral fellowships in the Biodiversity Centre at UBC next year! Am happy to chat if you might want to be hosted in my lab. biodiversity.ubc.ca/training-and... Deadline January 15th!
November 3, 2025 at 5:16 PM
We have TWO post-doctoral fellowships in the Biodiversity Centre at UBC next year! Am happy to chat if you might want to be hosted in my lab. biodiversity.ubc.ca/training-and... Deadline January 15th!
Reposted by Molly Przeworski
We are now accepting apps for our Simons Postdoctoral Fellowships in Plant Biology awards. Deadline is 12/4/2025: https://www.simonsfoundation.org/applications-for-simons-postdoctoral-fellowships-in-plant-biology-now-open/ #lifesciences
Applications for Simons Postdoctoral Fellowships in Plant Biology Now Open
Applications for Simons Postdoctoral Fellowships in Plant Biology Now Open on Simons Foundation
www.simonsfoundation.org
October 14, 2025 at 2:16 PM
We are now accepting apps for our Simons Postdoctoral Fellowships in Plant Biology awards. Deadline is 12/4/2025: https://www.simonsfoundation.org/applications-for-simons-postdoctoral-fellowships-in-plant-biology-now-open/ #lifesciences
Reposted by Molly Przeworski
I started a new job in Montpellier, France!
Happy about new opportunities, sad about the state of things in the US.
abetterscientist.wordpress.com/2025/10/26/w...
Happy about new opportunities, sad about the state of things in the US.
abetterscientist.wordpress.com/2025/10/26/w...
We left the US and moved to France
Hello readers, I got big updates! Some of you already know this, but it’s getting more real and more official every month: my family and I have left the US and moved to France! A few months ago I q…
abetterscientist.wordpress.com
October 27, 2025 at 7:19 PM
I started a new job in Montpellier, France!
Happy about new opportunities, sad about the state of things in the US.
abetterscientist.wordpress.com/2025/10/26/w...
Happy about new opportunities, sad about the state of things in the US.
abetterscientist.wordpress.com/2025/10/26/w...
Reposted by Molly Przeworski
The question isn’t "why does Signal use AWS?" It’s to look at the infrastructural requirements of any global, real-time, mass comms platform and ask how it is that we got to a place where there’s no realistic alternative to AWS and the other hyperscalers. 3/
October 27, 2025 at 10:38 AM
The question isn’t "why does Signal use AWS?" It’s to look at the infrastructural requirements of any global, real-time, mass comms platform and ask how it is that we got to a place where there’s no realistic alternative to AWS and the other hyperscalers. 3/
Reposted by Molly Przeworski
Amazing job opportunity at the @institutimagine.bsky.social, Head of the Genomics Platform.
I am adding an English translation of the opportunity, but fluency in French is a (reasonable) requirement for the position. Application link below.
www.welcometothejungle.com/fr/companies...
I am adding an English translation of the opportunity, but fluency in French is a (reasonable) requirement for the position. Application link below.
www.welcometothejungle.com/fr/companies...
October 23, 2025 at 7:14 PM
Amazing job opportunity at the @institutimagine.bsky.social, Head of the Genomics Platform.
I am adding an English translation of the opportunity, but fluency in French is a (reasonable) requirement for the position. Application link below.
www.welcometothejungle.com/fr/companies...
I am adding an English translation of the opportunity, but fluency in French is a (reasonable) requirement for the position. Application link below.
www.welcometothejungle.com/fr/companies...
Reposted by Molly Przeworski
Results I'm sad to share but must be told - branching coral are now functionally extinct in Florida - to learn more check out the full study www.science.org/doi/10.1126/... and our personal summary theconversation.com/2-iconic-cor...
Heat-driven functional extinction of Caribbean Acropora corals from Florida’s Coral Reef
In 2023, a record-setting marine heat wave triggered the ninth mass coral bleaching event on Florida’s Coral Reef (FCR). We examined spatial patterns of heat exposure along the ~560-kilometer length o...
www.science.org
October 23, 2025 at 6:26 PM
Results I'm sad to share but must be told - branching coral are now functionally extinct in Florida - to learn more check out the full study www.science.org/doi/10.1126/... and our personal summary theconversation.com/2-iconic-cor...
Reposted by Molly Przeworski
We're launching a portal to review federal immigration enforcement in New York after yesterday’s ICE raid on Canal Street.
New Yorkers who were present should submit videos or photos, and we will review and investigate any violations of the law.
New Yorkers who were present should submit videos or photos, and we will review and investigate any violations of the law.
Federal Action Reporting Form
Federal Action Reporting Form Please use this form to share information regarding federal government action in New York state. Filing a complaint does not start
ag.ny.gov
October 22, 2025 at 6:48 PM
We're launching a portal to review federal immigration enforcement in New York after yesterday’s ICE raid on Canal Street.
New Yorkers who were present should submit videos or photos, and we will review and investigate any violations of the law.
New Yorkers who were present should submit videos or photos, and we will review and investigate any violations of the law.
Reposted by Molly Przeworski
Are you looking for a PhD? Join us in Barcelona! You'll dive into a community of >100 PhD students from 30 countries exploring the frontiers of biology. You can also join an online workshop on 6 November (15:00 CET) to learn how to find the right lab for you.
More info: www.crg.eu/en/content/t...
More info: www.crg.eu/en/content/t...
October 23, 2025 at 7:56 AM
Are you looking for a PhD? Join us in Barcelona! You'll dive into a community of >100 PhD students from 30 countries exploring the frontiers of biology. You can also join an online workshop on 6 November (15:00 CET) to learn how to find the right lab for you.
More info: www.crg.eu/en/content/t...
More info: www.crg.eu/en/content/t...
Reposted by Molly Przeworski
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
October 15, 2025 at 3:53 PM
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
Reposted by Molly Przeworski
In Chicago, four vehicles descended and eight ICE agents moved in to kidnap a child.
She screams, “I’m 15,” as ICE yanks her from the car and kneels on her neck.
This is not about immigration enforcement.
It's about terrorizing Americans.
She screams, “I’m 15,” as ICE yanks her from the car and kneels on her neck.
This is not about immigration enforcement.
It's about terrorizing Americans.
October 11, 2025 at 6:20 PM
In Chicago, four vehicles descended and eight ICE agents moved in to kidnap a child.
She screams, “I’m 15,” as ICE yanks her from the car and kneels on her neck.
This is not about immigration enforcement.
It's about terrorizing Americans.
She screams, “I’m 15,” as ICE yanks her from the car and kneels on her neck.
This is not about immigration enforcement.
It's about terrorizing Americans.
Reposted by Molly Przeworski
Reposted by Molly Przeworski
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
October 9, 2025 at 2:06 PM
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Reposted by Molly Przeworski
Just an absolutely horrific self own, depleting the US of amazing students from all over the world who contributed to what used to make America great: its diversity, its openness, and its leadership in education.
The number of international students arriving in the U.S. in August fell by 19% this year compared with last year — the largest decline on record outside of the pandemic.
Nearly 20 Percent Fewer International Students Traveled to the U.S. in August
The data shows the steepest decline in August international student arrivals since the pandemic.
nyti.ms
October 6, 2025 at 4:40 PM
Just an absolutely horrific self own, depleting the US of amazing students from all over the world who contributed to what used to make America great: its diversity, its openness, and its leadership in education.
Reposted by Molly Przeworski
🔁 Please share - we remind the SMBE community that the Call for Symposia for SMBE2026 in Copenhagen is open.
We invite you to submit a symposium proposal to help shape the scientific content of our annual meeting.
🗓️ Deadline: October 15th
More information: smbe2026.org/symposia
#SMBE2026
We invite you to submit a symposium proposal to help shape the scientific content of our annual meeting.
🗓️ Deadline: October 15th
More information: smbe2026.org/symposia
#SMBE2026
October 1, 2025 at 8:33 AM
🔁 Please share - we remind the SMBE community that the Call for Symposia for SMBE2026 in Copenhagen is open.
We invite you to submit a symposium proposal to help shape the scientific content of our annual meeting.
🗓️ Deadline: October 15th
More information: smbe2026.org/symposia
#SMBE2026
We invite you to submit a symposium proposal to help shape the scientific content of our annual meeting.
🗓️ Deadline: October 15th
More information: smbe2026.org/symposia
#SMBE2026
Reposted by Molly Przeworski
The Damage Done: @marianneguenot.bsky.social tells the story of clinical trials derailed by the administration's reckless science policy, across kidney disease, HIV, Alzheimer's disease, and cancer. Years of work and money thrown away, at times just short of a cure.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The damage done - Nature Medicine
When clinical trials are suddenly halted by US funding cuts, there are repercussions for investigators and patients, and they do not stop at borders.
www.nature.com
September 30, 2025 at 10:27 PM
The Damage Done: @marianneguenot.bsky.social tells the story of clinical trials derailed by the administration's reckless science policy, across kidney disease, HIV, Alzheimer's disease, and cancer. Years of work and money thrown away, at times just short of a cure.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Molly Przeworski
Another violent attack by an ICE officer on a civilian at 26 Federal Plaza—this time on a journalist, who had to be carried out on stretcher.
Another attack on the First Amendment, our neighbors, and our democracy.
Another attack on the First Amendment, our neighbors, and our democracy.
September 30, 2025 at 4:23 PM
Another violent attack by an ICE officer on a civilian at 26 Federal Plaza—this time on a journalist, who had to be carried out on stretcher.
Another attack on the First Amendment, our neighbors, and our democracy.
Another attack on the First Amendment, our neighbors, and our democracy.
Reposted by Molly Przeworski
Mutation bias in driver genes reveals the distribution of effects of oncogenic mutations https://www.biorxiv.org/content/10.1101/2025.09.25.678277v1
September 29, 2025 at 3:32 AM
Mutation bias in driver genes reveals the distribution of effects of oncogenic mutations https://www.biorxiv.org/content/10.1101/2025.09.25.678277v1
Reposted by Molly Przeworski
Join us at the Hubrecht Institute in Utrecht to start your research group! Fantastic scientific environment, strong support, and nice colleagues :) Apply and please share broadly in your network.
Ready to establish your own research group at the Hubrecht Institute for Molecular and Developmental Biology? We’re seeking a tenure-track group leader to develop an innovative research line within our vibrant scientific community. Learn more & apply! https://f.mtr.cool/jncxfqkuds
September 28, 2025 at 9:43 AM
Join us at the Hubrecht Institute in Utrecht to start your research group! Fantastic scientific environment, strong support, and nice colleagues :) Apply and please share broadly in your network.
Reposted by Molly Przeworski
🎖️Congratulations to Carole Ober, PhD, winner of the ASHG 2025 Mentorship Award! Learn more about the award and Dr. Ober's work: https://www.ashg.org/membership/awards/2025-awardees/ #ASHG #HumanGenetic
August 28, 2025 at 6:45 PM
🎖️Congratulations to Carole Ober, PhD, winner of the ASHG 2025 Mentorship Award! Learn more about the award and Dr. Ober's work: https://www.ashg.org/membership/awards/2025-awardees/ #ASHG #HumanGenetic