Jess White
@jessbwhite.bsky.social
Current: Tri-I CBM student in @jchodera@bsky.social and Wesley Tansey labs
Previous: SWTX | OrbiMed | WeillCornellGS | BofAML | Penn | Andover
Employer-mandated disclaimer: choderalab.org/disclaimer
Previous: SWTX | OrbiMed | WeillCornellGS | BofAML | Penn | Andover
Employer-mandated disclaimer: choderalab.org/disclaimer
Pinned
Jess White
@jessbwhite.bsky.social
· Dec 12
I'm honored to share that I've been selected as a 2026 PhRMA Foundation Predoctoral Fellow in Drug Discovery. This fellowship will support my research assessing how clinically relevant missense mutations impact kinase activity.
Read more about our work here.
Read more about our work here.
Reposted by Jess White
OpenBind is a new open science effort to dramatically increase the number of protein:ligand structures in the PDB, pairing this with high-quality affinity data to enable a new generation of predictive structure and affinity models for drug discovery. Check it out: openbind.ai
January 12, 2026 at 2:54 PM
OpenBind is a new open science effort to dramatically increase the number of protein:ligand structures in the PDB, pairing this with high-quality affinity data to enable a new generation of predictive structure and affinity models for drug discovery. Check it out: openbind.ai
I'm honored to share that I've been selected as a 2026 PhRMA Foundation Predoctoral Fellow in Drug Discovery. This fellowship will support my research assessing how clinically relevant missense mutations impact kinase activity.
Read more about our work here.
Read more about our work here.
December 12, 2025 at 3:06 PM
I'm honored to share that I've been selected as a 2026 PhRMA Foundation Predoctoral Fellow in Drug Discovery. This fellowship will support my research assessing how clinically relevant missense mutations impact kinase activity.
Read more about our work here.
Read more about our work here.
Reposted by Jess White
Achira is growing! We’re looking for talented software engineers, ML research engineers, and AI/ML scientists to join our team in building foundation simulation models to power the future of drug discovery.
Apply at achira.ai
Apply at achira.ai
Achira
Building foundation simulation models for drug discovery
achira.ai
October 24, 2025 at 12:20 PM
Achira is growing! We’re looking for talented software engineers, ML research engineers, and AI/ML scientists to join our team in building foundation simulation models to power the future of drug discovery.
Apply at achira.ai
Apply at achira.ai
Reposted by Jess White
How many crystal structures do you need to trust your docking results? [new]
Accurate drug docking needs crystal struct. Template docking via mol. similarity helps w/ ltd. data.
Accurate drug docking needs crystal struct. Template docking via mol. similarity helps w/ ltd. data.
September 25, 2025 at 2:54 AM
How many crystal structures do you need to trust your docking results? [new]
Accurate drug docking needs crystal struct. Template docking via mol. similarity helps w/ ltd. data.
Accurate drug docking needs crystal struct. Template docking via mol. similarity helps w/ ltd. data.
Reposted by Jess White
@jengreitz.bsky.social l & my lab want to co-hire a computational biologist/biostatistician with project management expertise to help map the regulatory code of the human genome and discover genetic mechanisms of disease.
Details below
careersearch.stanford.edu/jobs/computa...
Plz RT
Details below
careersearch.stanford.edu/jobs/computa...
Plz RT
August 19, 2025 at 12:29 AM
@jengreitz.bsky.social l & my lab want to co-hire a computational biologist/biostatistician with project management expertise to help map the regulatory code of the human genome and discover genetic mechanisms of disease.
Details below
careersearch.stanford.edu/jobs/computa...
Plz RT
Details below
careersearch.stanford.edu/jobs/computa...
Plz RT
Reposted by Jess White
Mark your calendars for the ACS COMP *SUNDAY* Social on August 17, 2025! Free German 🥨&🍻 for COMP members, sponsored by OpenEye + Cadence 💻
RSVP link dropping soon in all ACS COMP members' email inboxes :)
RSVP link dropping soon in all ACS COMP members' email inboxes :)
July 22, 2025 at 8:47 PM
Reposted by Jess White
The steady deterioration of First Amendment rights and the conflation of violence with dissent is a result not just of an authoritarian regime but of a press culture that is feckless at best and authoritarian-fluffers at worst. The New York Times is beyond redemption.
The killings of two Israeli Embassy workers in Washington on Wednesday cast a harsh spotlight on the pro-Palestinian movement in the U.S. and the impact even peaceful protests might be having on attitudes against people connected to Israel.
Pro-Palestinian Movement Faces an Uncertain Path After Embassy Attack
www.nytimes.com
May 23, 2025 at 4:34 PM
The steady deterioration of First Amendment rights and the conflation of violence with dissent is a result not just of an authoritarian regime but of a press culture that is feckless at best and authoritarian-fluffers at worst. The New York Times is beyond redemption.
Grateful for the opportunity to present my work to such an engaged audience! Find out more here: bit.ly/4kcOQnX #Kinase2025
May 13, 2025 at 5:30 PM
Grateful for the opportunity to present my work to such an engaged audience! Find out more here: bit.ly/4kcOQnX #Kinase2025
This could be incredibly dangerous
April 11, 2025 at 2:20 AM
This could be incredibly dangerous
Communicate your opposition to the cancelation of billions of dollars in pandemic preparedness grants to all of your elected representatives simultaneously here: resist.bot/petitions/PX...
March 27, 2025 at 6:15 PM
Communicate your opposition to the cancelation of billions of dollars in pandemic preparedness grants to all of your elected representatives simultaneously here: resist.bot/petitions/PX...
Reposted by Jess White
In honor of #MarchMadness, let's talk about how all 8 men's teams playing in Providence this week are threatened by the Musk/Trump Admin.
If you love college sports, you're going to have to stand up for colleges!!!!
If you love college sports, you're going to have to stand up for colleges!!!!
March 19, 2025 at 6:42 PM
In honor of #MarchMadness, let's talk about how all 8 men's teams playing in Providence this week are threatened by the Musk/Trump Admin.
If you love college sports, you're going to have to stand up for colleges!!!!
If you love college sports, you're going to have to stand up for colleges!!!!
Reposted by Jess White
This work is now published in J Phys Chem B! Check out our work showing that simulations predict the impact of distal mutations on kinase-inhibitor binding, and our experimental NanoBRET dataset of 94 kinase mutations that provide a benchmark for future methods. Link:
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
March 10, 2025 at 6:19 PM
This work is now published in J Phys Chem B! Check out our work showing that simulations predict the impact of distal mutations on kinase-inhibitor binding, and our experimental NanoBRET dataset of 94 kinase mutations that provide a benchmark for future methods. Link:
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
Reposted by Jess White
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
www.nytimes.com/2025/03/01/u...
March 1, 2025 at 6:07 PM
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
www.nytimes.com/2025/03/01/u...
Reposted by Jess White
Everything is chaos, but I wanted to share some awesome recent science from the lab that hints at where the future of biomolecular simulation is headed:
Foundation simulation models that can be fine-tuned to experimental free energy data to produce systematically more accurate predictions.
Foundation simulation models that can be fine-tuned to experimental free energy data to produce systematically more accurate predictions.
February 19, 2025 at 7:30 PM
Everything is chaos, but I wanted to share some awesome recent science from the lab that hints at where the future of biomolecular simulation is headed:
Foundation simulation models that can be fine-tuned to experimental free energy data to produce systematically more accurate predictions.
Foundation simulation models that can be fine-tuned to experimental free energy data to produce systematically more accurate predictions.
Reposted by Jess White
🧵 on our preprint: Zhang & Skolnick's TM score for comparing model of protein to experimental structures of same protein. The d_j are essentially the same as the aligned error in Alphafold. After any structure alignment, it's the displacement of model Calpha from experimental Calpha of residue j.
February 16, 2025 at 2:13 AM
🧵 on our preprint: Zhang & Skolnick's TM score for comparing model of protein to experimental structures of same protein. The d_j are essentially the same as the aligned error in Alphafold. After any structure alignment, it's the displacement of model Calpha from experimental Calpha of residue j.
Reposted by Jess White
Excited to be in LA for #BPS2025 @biophysicalsoc.bsky.social! I’ll be presenting a poster on our high-throughput fluorescence-based assay for kinase inhibitor binding in the West Exhibit Hall on Monday at 2:45 PM (board B60).
February 16, 2025 at 6:47 PM
Excited to be in LA for #BPS2025 @biophysicalsoc.bsky.social! I’ll be presenting a poster on our high-throughput fluorescence-based assay for kinase inhibitor binding in the West Exhibit Hall on Monday at 2:45 PM (board B60).
Reposted by Jess White
I'll be presenting my work prospectively studying clinical mutations and their impact on kinase inhibitor binding at #bps2025! Come see my talk on Wednesday morning @ 8:45am.
February 16, 2025 at 6:53 PM
I'll be presenting my work prospectively studying clinical mutations and their impact on kinase inhibitor binding at #bps2025! Come see my talk on Wednesday morning @ 8:45am.
Reposted by Jess White
1. Today the NIH director issued a new directive slashing overhead rates to 15%.
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
grants.nih.gov
February 8, 2025 at 12:18 AM
1. Today the NIH director issued a new directive slashing overhead rates to 15%.
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
Reposted by Jess White
#MLCB2025 will be Sept 10-11 at @nygenome.org in NYC! Paper deadline June 1st & in-person registration will open in May. Please sign up for our mailing list groups.google.com/g/mlcb/ for future announcements. More details at mlcb.github.io. Please RP!
January 27, 2025 at 6:40 PM
#MLCB2025 will be Sept 10-11 at @nygenome.org in NYC! Paper deadline June 1st & in-person registration will open in May. Please sign up for our mailing list groups.google.com/g/mlcb/ for future announcements. More details at mlcb.github.io. Please RP!
Reposted by Jess White
🏁 The antiviral challenge is live! 🏁
Ready to test your skills on new data? Hosted in partnership with @asapdiscovery.bsky.social and @omsf.io, we've prepared detailed notebooks showcasing how to format your data and submit your solutions. 🧑💻
Ready to test your skills on new data? Hosted in partnership with @asapdiscovery.bsky.social and @omsf.io, we've prepared detailed notebooks showcasing how to format your data and submit your solutions. 🧑💻
January 14, 2025 at 2:31 PM
🏁 The antiviral challenge is live! 🏁
Ready to test your skills on new data? Hosted in partnership with @asapdiscovery.bsky.social and @omsf.io, we've prepared detailed notebooks showcasing how to format your data and submit your solutions. 🧑💻
Ready to test your skills on new data? Hosted in partnership with @asapdiscovery.bsky.social and @omsf.io, we've prepared detailed notebooks showcasing how to format your data and submit your solutions. 🧑💻
Happy to have been a member of the BATCHIE team who worked on this recent publication featured by @MSKLibrary: A Bayesian active learning platform for scalable combination drug screens dx.doi.org/10.1038/s414...
A Bayesian active learning platform for scalable combination drug screens - Nature Communications
Large-scale combination drug screens in cancer are extremely challenging because of the immense number of possible combinations. Here, the authors develop BATCHIE, a Bayesian active learning platform ...
dx.doi.org
January 14, 2025 at 3:04 PM
Happy to have been a member of the BATCHIE team who worked on this recent publication featured by @MSKLibrary: A Bayesian active learning platform for scalable combination drug screens dx.doi.org/10.1038/s414...
Reposted by Jess White
🦠 We’re excited to announce our first competition in partnership with @asapdiscovery.bsky.social and @omsf.io!
Test your skills across three sub-challenges revolving around SARS-CoV-2 and MERS-CoV Mpro🧵
Full details: polarishub.io/competitions
Blog: polarishub.io/blog/antivir...
Test your skills across three sub-challenges revolving around SARS-CoV-2 and MERS-CoV Mpro🧵
Full details: polarishub.io/competitions
Blog: polarishub.io/blog/antivir...
December 3, 2024 at 3:13 PM
🦠 We’re excited to announce our first competition in partnership with @asapdiscovery.bsky.social and @omsf.io!
Test your skills across three sub-challenges revolving around SARS-CoV-2 and MERS-CoV Mpro🧵
Full details: polarishub.io/competitions
Blog: polarishub.io/blog/antivir...
Test your skills across three sub-challenges revolving around SARS-CoV-2 and MERS-CoV Mpro🧵
Full details: polarishub.io/competitions
Blog: polarishub.io/blog/antivir...
Reposted by Jess White
Automated plate handling in the Chodera Lab, part of our effort to study kinase inhibitors in high throughput.
November 27, 2024 at 4:44 PM
Automated plate handling in the Chodera Lab, part of our effort to study kinase inhibitors in high throughput.
Reposted by Jess White
Thrilled to announce Boltz-1, the first open-source and commercially available model to achieve AlphaFold3-level accuracy on biomolecular structure prediction! An exciting collaboration with Jeremy, Saro, and an amazing team at MIT and Genesis Therapeutics. A thread!
November 17, 2024 at 4:20 PM
Thrilled to announce Boltz-1, the first open-source and commercially available model to achieve AlphaFold3-level accuracy on biomolecular structure prediction! An exciting collaboration with Jeremy, Saro, and an amazing team at MIT and Genesis Therapeutics. A thread!
Reposted by Jess White
Here’s another critical piece of info about Bhattacharya: Multiple judges in court cases over COVID mitigations where he’s been been used as an expert have called his expertise into question.
www.importantcontext.news/p/judges-kee...
www.importantcontext.news/p/judges-kee...
Judges Keep Questioning Herd Immunity Advocate’s Credibility
"At this stage of the proceedings, the Court is simply unwilling to trust Dr. Bhattacharya."
www.importantcontext.news
November 16, 2024 at 6:35 PM
Here’s another critical piece of info about Bhattacharya: Multiple judges in court cases over COVID mitigations where he’s been been used as an expert have called his expertise into question.
www.importantcontext.news/p/judges-kee...
www.importantcontext.news/p/judges-kee...