Indra Roux
@indraroux.bsky.social
Postdoc at Univ of Cambridge MRC Tox🇬🇧 PhD UWA🇦🇺 Biotech UNQ🇦🇷🧬🛠️ #Microbiology #EngineeringBiology #ChemicalBiology #Microbiome #Genetics She/her Latinx https://scholar.google.com/citations?user=RNoSH60AAAAJ&hl=en
Pinned
Indra Roux
@indraroux.bsky.social
· Jun 26
"What does Engineering Biology mean to you?"
We invited members of the #EngBio community to share their definition of this evolving field. This is what Dr Indra Roux (@indraroux.bsky.social), Postdoctoral Researcher at the MRC Toxicology Unit (@mrc-tu.bsky.social), had to say.
#FacesOfEngBio
We invited members of the #EngBio community to share their definition of this evolving field. This is what Dr Indra Roux (@indraroux.bsky.social), Postdoctoral Researcher at the MRC Toxicology Unit (@mrc-tu.bsky.social), had to say.
#FacesOfEngBio
My definition of #EngineeringBiology has expanded: from synthetic biology in model chassis to designing diverse synthetic microbial communities. Many complex and resilient functions emerge at the microbiome level, so synthetic ecology is a promising approach for robust biotech. #FacesOfEngBio 🧬⚒️🧫
Reposted by Indra Roux
Ever wondered how antidepressants might influence your gut microbes? 🧬💊Join Dr. Xiaoteng Jiang ( @mrc-tu.bsky.social ) talk on Nov 20, 16:30h at @cambiochem.bsky.social to explore how RNA–protein interactions reveal unexpected drug–microbiome connections 🤯
a blue background with purple and green swirls
ALT: a blue background with purple and green swirls
media.tenor.com
November 7, 2025 at 12:58 PM
Ever wondered how antidepressants might influence your gut microbes? 🧬💊Join Dr. Xiaoteng Jiang ( @mrc-tu.bsky.social ) talk on Nov 20, 16:30h at @cambiochem.bsky.social to explore how RNA–protein interactions reveal unexpected drug–microbiome connections 🤯
Reposted by Indra Roux
There is still time to register for the EngBio Forum on Monday.
It's free to attend with a great speaker line up - Andreas Walther @waltherlab.bsky.social and Claudia Contini @continiclau.bsky.social exploring #SyntheticCells #LifeLikeSystems #EngineeringBiology
🎟️🫱 buytickets.at/engineeringb...
It's free to attend with a great speaker line up - Andreas Walther @waltherlab.bsky.social and Claudia Contini @continiclau.bsky.social exploring #SyntheticCells #LifeLikeSystems #EngineeringBiology
🎟️🫱 buytickets.at/engineeringb...
November 5, 2025 at 10:30 AM
There is still time to register for the EngBio Forum on Monday.
It's free to attend with a great speaker line up - Andreas Walther @waltherlab.bsky.social and Claudia Contini @continiclau.bsky.social exploring #SyntheticCells #LifeLikeSystems #EngineeringBiology
🎟️🫱 buytickets.at/engineeringb...
It's free to attend with a great speaker line up - Andreas Walther @waltherlab.bsky.social and Claudia Contini @continiclau.bsky.social exploring #SyntheticCells #LifeLikeSystems #EngineeringBiology
🎟️🫱 buytickets.at/engineeringb...
Reposted by Indra Roux
We're excited to help launch the inaugural Gordon research conference on #microbiome editing, coming up in January in Pomona, CA! Learn more and register here: https://ow.ly/a6Am50X9XkE
October 27, 2025 at 3:05 PM
We're excited to help launch the inaugural Gordon research conference on #microbiome editing, coming up in January in Pomona, CA! Learn more and register here: https://ow.ly/a6Am50X9XkE
Reposted by Indra Roux
Tyler Myers, an MPhil student in the Patil Lab, is one of the speakers at the next Neurotalks.
Hear more about our second brain in the latest edition of Neurotalks and learn about the pain of chillis, IBD, gut microbiome and drugs, and listening to the gut in action.
Hear more about our second brain in the latest edition of Neurotalks and learn about the pain of chillis, IBD, gut microbiome and drugs, and listening to the gut in action.
November 4, 2025 at 3:27 PM
Tyler Myers, an MPhil student in the Patil Lab, is one of the speakers at the next Neurotalks.
Hear more about our second brain in the latest edition of Neurotalks and learn about the pain of chillis, IBD, gut microbiome and drugs, and listening to the gut in action.
Hear more about our second brain in the latest edition of Neurotalks and learn about the pain of chillis, IBD, gut microbiome and drugs, and listening to the gut in action.
Reposted by Indra Roux
Growth-coupled microbial biosynthesis of the animal pigment xanthommatin — Led by Leah Bushin, featuring M. Gracia Alvan, @danielvolke.bsky.social @oscarpuiggene.bsky.social in a fantastic collaboration w/Brad Moore @labnikel.bsky.social @natbiotech.nature.com 🦑
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 3, 2025 at 12:49 PM
Growth-coupled microbial biosynthesis of the animal pigment xanthommatin — Led by Leah Bushin, featuring M. Gracia Alvan, @danielvolke.bsky.social @oscarpuiggene.bsky.social in a fantastic collaboration w/Brad Moore @labnikel.bsky.social @natbiotech.nature.com 🦑
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Indra Roux
Is science too obsessed with metrics, large-scale projects & “blockbuster” outputs? Desai & Jun argued that preserving the "auteur" spirit of individual creativity, exploration and risk-taking is essential for maintaining the creativity that drew us into science in the 1st place.
November 3, 2025 at 2:50 AM
Is science too obsessed with metrics, large-scale projects & “blockbuster” outputs? Desai & Jun argued that preserving the "auteur" spirit of individual creativity, exploration and risk-taking is essential for maintaining the creativity that drew us into science in the 1st place.
Reposted by Indra Roux
A brand-new Gordon Conference on Microbiomes!🦠 The opening session (Jan 2026) dives into microbiome editing - how fundamental research and new technologies can advance human health and environmental sustainability. Super looking forward!🧪 #microsky #microbiomesky #grc
www.grc.org/microbiome-e...
www.grc.org/microbiome-e...
2026 Microbiome Editing Conference GRC
The 2026 Gordon Research Conference on Microbiome Editing will be held in Pomona, California. Apply today to reserve your spot.
www.grc.org
October 31, 2025 at 9:42 AM
A brand-new Gordon Conference on Microbiomes!🦠 The opening session (Jan 2026) dives into microbiome editing - how fundamental research and new technologies can advance human health and environmental sustainability. Super looking forward!🧪 #microsky #microbiomesky #grc
www.grc.org/microbiome-e...
www.grc.org/microbiome-e...
Reposted by Indra Roux
Deep-learning-based virtual screening of antibacterial compounds go.nature.com/47oIdKy
Deep-learning-based virtual screening of antibacterial compounds - Nature Biotechnology
Antibacterial compounds are discovered by combining phenotypic screening with deep learning.
go.nature.com
October 24, 2025 at 3:39 PM
Deep-learning-based virtual screening of antibacterial compounds go.nature.com/47oIdKy
Reposted by Indra Roux
Pleased to have contributed to this Genentech-led research with NVIDIA featured today in @natbiotech.nature.com presenting GNEprop, an AI model that identifies novel antimicrobial compounds beyond known chemical space. Mila’s contributions were led by @yoshuabengio.bsky.social & Michał Koziarski.
Deep-learning-based virtual screening of antibacterial compounds go.nature.com/47oIdKy
Deep-learning-based virtual screening of antibacterial compounds - Nature Biotechnology
Antibacterial compounds are discovered by combining phenotypic screening with deep learning.
go.nature.com
October 24, 2025 at 7:42 PM
Pleased to have contributed to this Genentech-led research with NVIDIA featured today in @natbiotech.nature.com presenting GNEprop, an AI model that identifies novel antimicrobial compounds beyond known chemical space. Mila’s contributions were led by @yoshuabengio.bsky.social & Michał Koziarski.
Reposted by Indra Roux
In a new series, we're introducing you to some of our #EngBio Early Career Researchers.
Meet Nikos Nikolopoulos, Postdoctoral Research Fellow, Department of Medicine Molecular Immunity Unit (MIU) at @mrclmb.bsky.social. View Nikos' profile: www.engbio.cam.ac.uk/nikos-nikolo...
#EngBioECRs
Meet Nikos Nikolopoulos, Postdoctoral Research Fellow, Department of Medicine Molecular Immunity Unit (MIU) at @mrclmb.bsky.social. View Nikos' profile: www.engbio.cam.ac.uk/nikos-nikolo...
#EngBioECRs
October 27, 2025 at 11:00 AM
In a new series, we're introducing you to some of our #EngBio Early Career Researchers.
Meet Nikos Nikolopoulos, Postdoctoral Research Fellow, Department of Medicine Molecular Immunity Unit (MIU) at @mrclmb.bsky.social. View Nikos' profile: www.engbio.cam.ac.uk/nikos-nikolo...
#EngBioECRs
Meet Nikos Nikolopoulos, Postdoctoral Research Fellow, Department of Medicine Molecular Immunity Unit (MIU) at @mrclmb.bsky.social. View Nikos' profile: www.engbio.cam.ac.uk/nikos-nikolo...
#EngBioECRs
Reposted by Indra Roux
From #drug cabinet → gut #microbiome: screening 312 therapeutic compounds, we mapped 4.6 million microbial protein-level responses to reveal how our drugs don’t just target us, they hit our gut microbes too.
rdcu.be/eMmcT
rdcu.be/eMmcT
October 26, 2025 at 7:09 AM
From #drug cabinet → gut #microbiome: screening 312 therapeutic compounds, we mapped 4.6 million microbial protein-level responses to reveal how our drugs don’t just target us, they hit our gut microbes too.
rdcu.be/eMmcT
rdcu.be/eMmcT
Reposted by Indra Roux
Working on tailoring enzymes and want to learn more about the MITE database? We are organizing a hands-on training session on how use the DB and create new entries: October 30th and November 4th 10-11 am Amsterdam time. Sign up here: forms.gle/KHPqe9XV1RRg... See you there! #secmet #natprod
MITE training session registration form
Registration form for mailing list
forms.gle
October 24, 2025 at 1:37 PM
Working on tailoring enzymes and want to learn more about the MITE database? We are organizing a hands-on training session on how use the DB and create new entries: October 30th and November 4th 10-11 am Amsterdam time. Sign up here: forms.gle/KHPqe9XV1RRg... See you there! #secmet #natprod
Reposted by Indra Roux
Explore emerging research with field leaders @keystonesymposia.bsky.social #Microbiome Metabolism & #Metabolites, this January in Banff! @molsystbiol.org scientific editor Poonam Bheda will attend.
Early registration deadline is Nov 20th => keysym.us/KSMicroMetab26 #KSMicroMetab26
Early registration deadline is Nov 20th => keysym.us/KSMicroMetab26 #KSMicroMetab26
Microbiome Metabolism and Metabolites: Discovery and Function in Health and Disease | Keystone Symposia
Join us at the Keystone Symposia on Microbiome Metabolism and Metabolites: Discovery and Function in Health and Disease, January 2026, in Banff, with field leaders!
keysym.us
October 23, 2025 at 12:12 PM
Explore emerging research with field leaders @keystonesymposia.bsky.social #Microbiome Metabolism & #Metabolites, this January in Banff! @molsystbiol.org scientific editor Poonam Bheda will attend.
Early registration deadline is Nov 20th => keysym.us/KSMicroMetab26 #KSMicroMetab26
Early registration deadline is Nov 20th => keysym.us/KSMicroMetab26 #KSMicroMetab26
Reposted by Indra Roux
Interested in #drugs, #microbiome and #antibiotic resistance, then check out our paper on the effects of over 300 drugs on the gut microbiome. Exciting results as well on the role of antibiotic resistance defining how microbiomes respond to drugs.
@quadraminstitute.bsky.social
rdcu.be/eMmcT
@quadraminstitute.bsky.social
rdcu.be/eMmcT
Systematic metaproteomics mapping reveals functional and ecological landscapes of Ex vivo human gut microbiota responses to therapeutic drugs
Nature Communications - Here, the authors systematically map metaproteomic responses of ex vivo human gut microbiota to common therapeutics, identifying several drug classes inducing strong...
rdcu.be
October 24, 2025 at 4:20 PM
Interested in #drugs, #microbiome and #antibiotic resistance, then check out our paper on the effects of over 300 drugs on the gut microbiome. Exciting results as well on the role of antibiotic resistance defining how microbiomes respond to drugs.
@quadraminstitute.bsky.social
rdcu.be/eMmcT
@quadraminstitute.bsky.social
rdcu.be/eMmcT
Reposted by Indra Roux
Identification of human gut bacteria that produce bioactive serotonin and promote colonic innervation
www.cell.com/cell-reports...
Serotonin produced by gut bacteria provides hope for a novel IBS treatment
medicalxpress.com/news/2025-10...
www.cell.com/cell-reports...
Serotonin produced by gut bacteria provides hope for a novel IBS treatment
medicalxpress.com/news/2025-10...
Identification of human gut bacteria that produce bioactive serotonin and promote colonic innervation
Moretti et al. show a gut bacterial consortium (L. mucosae and L. ruminis) producing
serotonin, increasing fecal serotonin and enteric neuron density and normalizing intestinal
motility in mice. Reduc...
www.cell.com
October 21, 2025 at 12:13 AM
Identification of human gut bacteria that produce bioactive serotonin and promote colonic innervation
www.cell.com/cell-reports...
Serotonin produced by gut bacteria provides hope for a novel IBS treatment
medicalxpress.com/news/2025-10...
www.cell.com/cell-reports...
Serotonin produced by gut bacteria provides hope for a novel IBS treatment
medicalxpress.com/news/2025-10...
Reposted by Indra Roux
Please join us at Café Synthetique on 3 Nov with talks:
🍶Gut feelings: engineering smart probiotics that can sense disease @driglar.bsky.social
🧫Seeing Nanomaterials in Action, from Cellular Senescence to NanoDynamic Imaging - Andrew Baker @phar.cam.ac.uk
🎟️👉 www.tickettailor.com/events/engin...
🍶Gut feelings: engineering smart probiotics that can sense disease @driglar.bsky.social
🧫Seeing Nanomaterials in Action, from Cellular Senescence to NanoDynamic Imaging - Andrew Baker @phar.cam.ac.uk
🎟️👉 www.tickettailor.com/events/engin...
October 15, 2025 at 10:58 AM
Please join us at Café Synthetique on 3 Nov with talks:
🍶Gut feelings: engineering smart probiotics that can sense disease @driglar.bsky.social
🧫Seeing Nanomaterials in Action, from Cellular Senescence to NanoDynamic Imaging - Andrew Baker @phar.cam.ac.uk
🎟️👉 www.tickettailor.com/events/engin...
🍶Gut feelings: engineering smart probiotics that can sense disease @driglar.bsky.social
🧫Seeing Nanomaterials in Action, from Cellular Senescence to NanoDynamic Imaging - Andrew Baker @phar.cam.ac.uk
🎟️👉 www.tickettailor.com/events/engin...
Reposted by Indra Roux
A week to go... #EngBio ECRs Meetup returns on 20 Oct. Join us to hear great talks from Konstantina Beritza and
Caroline Faessler 🌱 Don't miss it!
@camplantsci.bsky.social
Sign up here👉 www.tickettailor.com/events/engin...
#plantsciences #marinemicroalga #Nicotianabenthamiana
Caroline Faessler 🌱 Don't miss it!
@camplantsci.bsky.social
Sign up here👉 www.tickettailor.com/events/engin...
#plantsciences #marinemicroalga #Nicotianabenthamiana
October 13, 2025 at 9:43 AM
A week to go... #EngBio ECRs Meetup returns on 20 Oct. Join us to hear great talks from Konstantina Beritza and
Caroline Faessler 🌱 Don't miss it!
@camplantsci.bsky.social
Sign up here👉 www.tickettailor.com/events/engin...
#plantsciences #marinemicroalga #Nicotianabenthamiana
Caroline Faessler 🌱 Don't miss it!
@camplantsci.bsky.social
Sign up here👉 www.tickettailor.com/events/engin...
#plantsciences #marinemicroalga #Nicotianabenthamiana
Reposted by Indra Roux
Pandas, snow leopards...and bacteria. A newly formed team of scientists is setting out to conserve the world's diversity of microbes. Here's my story: nyti.ms/47vEfRC
October 17, 2025 at 12:58 PM
Pandas, snow leopards...and bacteria. A newly formed team of scientists is setting out to conserve the world's diversity of microbes. Here's my story: nyti.ms/47vEfRC
Reposted by Indra Roux
SAVE THE DATE: 27 October, 2025
and join speakers from both illumina and #MVIF!
Registration for the webinar is free: emea.illumina.com/events/webin...
and join speakers from both illumina and #MVIF!
Registration for the webinar is free: emea.illumina.com/events/webin...
October 10, 2025 at 1:58 PM
SAVE THE DATE: 27 October, 2025
and join speakers from both illumina and #MVIF!
Registration for the webinar is free: emea.illumina.com/events/webin...
and join speakers from both illumina and #MVIF!
Registration for the webinar is free: emea.illumina.com/events/webin...
Reposted by Indra Roux
We're excited to help launch the inaugural Gordon Research Conference on #microbiome #GenomeEditing, coming up in January in Pomona, CA! Learn more and register here: https://ow.ly/63z150X9XkG
October 16, 2025 at 3:05 PM
We're excited to help launch the inaugural Gordon Research Conference on #microbiome #GenomeEditing, coming up in January in Pomona, CA! Learn more and register here: https://ow.ly/63z150X9XkG
Reposted by Indra Roux
μGrowthDB: querying, visualizing, and sharing microbial growth curve data www.biorxiv.org/content/10.1... #jcampubs
October 14, 2025 at 3:28 PM
μGrowthDB: querying, visualizing, and sharing microbial growth curve data www.biorxiv.org/content/10.1... #jcampubs
Reposted by Indra Roux
If you feel like contributing your microbial growth data, take a look at μGrowthDB
mgrowthdb.gbiomed.kuleuven.be
You can also read the preprint: www.biorxiv.org/content/10.1...
🧬🖥️🧪🦠🧫
mgrowthdb.gbiomed.kuleuven.be
You can also read the preprint: www.biorxiv.org/content/10.1...
🧬🖥️🧪🦠🧫
October 14, 2025 at 3:07 PM
If you feel like contributing your microbial growth data, take a look at μGrowthDB
mgrowthdb.gbiomed.kuleuven.be
You can also read the preprint: www.biorxiv.org/content/10.1...
🧬🖥️🧪🦠🧫
mgrowthdb.gbiomed.kuleuven.be
You can also read the preprint: www.biorxiv.org/content/10.1...
🧬🖥️🧪🦠🧫
Reposted by Indra Roux
Predicting functions of uncharacterized gene products from microbial communities www.nature.com/articles/s41... #jcampubs
Predicting functions of uncharacterized gene products from microbial communities - Nature Biotechnology
FUGAsseM predicts protein function in microbiomes using coexpression patterns from metatranscriptomes and diverse community-wide data.
www.nature.com
October 15, 2025 at 3:17 PM
Predicting functions of uncharacterized gene products from microbial communities www.nature.com/articles/s41... #jcampubs
Reposted by Indra Roux
Amazing resource—hope it gets used broadly and we see TnSeq datasets become more common for Bacteroidales.
Excited to share our preprint led by Carlos Voogdt et al
We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
October 13, 2025 at 8:43 PM
Amazing resource—hope it gets used broadly and we see TnSeq datasets become more common for Bacteroidales.
Reposted by Indra Roux
Excited to share our preprint led by Carlos Voogdt et al
We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
October 13, 2025 at 11:25 AM