Specialists in the 'dirty wars' of the Eighties encouraged the plotters who tried to topple President Chavez.

In historical viral epidemics, such as the H1N1 influenza and Zika viruses, prenatal exposures were correlated with risk for neuropsychiatric conditio…

Author summary There are several families of viruses that scientists predict are most likely to cause a future pandemic, such as coronaviruses or Ebola. Studying these viruses ahead of time might mean...

As heatwaves, floods and storms worsen across Africa, experts reveal a growing mental health toll that many organisations are ignoring.

Background Emerging infectious diseases (EIDs) pose ongoing global health threats, making it essential to understand their temporal, geographic, and biological patterns to inform prevention and contro...

Tesla announced it delivered 418,227 cars in the fourth quarter of 2025, as the carmaker ceded the crown of the world’s biggest EV maker to Chinese rival BYD for the first time.

The president, his family and some of their closest associates have engaged in a sprawling campaign of deals that stretches across industries and the globe.

Exclusive: Pilot scheme launches as one in five start primary school with no protection against deadly diseases

Agreement requires agency to evaluate hundreds of applications “in good faith” using its standard process

It’s hard to measure social and economic impacts of making papers and data free, researchers say

Trump administration declines to renew appointment of Walter Koroshetz, against NIH director’s wishes

Here the authors show that persistent antigen stimulation drives the generation of CD8+ tissue-resident exhausted T cells with distinct developmental origins, function and therapeutic responsiveness w...

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Background The coronavirus disease 2019 (COVID-19) affects multiple body systems, causing lasting effects on metabolic, endocrine, renal, and hematological functions. While vaccination is known to les...

Climate change made 213 historical heatwaves reported over 2000–2023 more likely and more intense, to which each of the 180 carbon majors (fossil fuel and cement producers) substantially contributed.

Lung development generates a complex tree-like architecture through proximal-distal patterning and branching morphogenesis. However, the gene regulatory programs governing embryonic lung development remain poorly understood. Here, we present a comprehensive single-cell multi-omics atlas of mouse embryonic lungs, integrating gene expression and chromatin accessibility profiles. Through systematic analysis, we identify 13 distinct cell types and map cis-regulatory elements, peak-to-gene linkages, and transcription factors underlying lung development. Leveraging this multi-modal dataset, we uncover lineage-determining transcription factors driving cell differentiation, including the Activated Protein-1 complex. We further delineate gene regulatory networks involving diverse transcription regulators, including CCCTC-binding factor (CTCF). Using the Ctcf conditional knockout mouse, coupled with histological and multi-omics analyses, we demonstrate that CTCF orchestrates lung progenitor main