@i2bcparissaclay.bsky.social
Pinned
I2BC Paris-Saclay | Scoop.it
Scoop.it enables professionals and businesses to research and publish content through its content curation tool.
www.scoop.it
Dear I2BC colleagues, if you want to have a look at the I2BC Scoop-it page, please follow this link: www.scoop.it/u/institut-d...
Olga Soutourina from @univparissaclay - #I2BC - will talk about alternative to current antibiotics & antivirals at the 9th edition of Immunotherapies & Innovations for Infectious Diseases congress, organized by MabDesign 13-14 November 25 - ENS, Lyon, Fr i4id.org
#Immunotherapy #InfectiousDiseases
#Immunotherapy #InfectiousDiseases
November 6, 2025 at 3:09 PM
Olga Soutourina from @univparissaclay - #I2BC - will talk about alternative to current antibiotics & antivirals at the 9th edition of Immunotherapies & Innovations for Infectious Diseases congress, organized by MabDesign 13-14 November 25 - ENS, Lyon, Fr i4id.org
#Immunotherapy #InfectiousDiseases
#Immunotherapy #InfectiousDiseases
Reposted
I am very proud to announce that our team has received an ERC synergy grant from @erc.europa.eu. A wonderful recognition of a truly collaborative effort with friends (Julius Lukes, Leos Valasek and Mark Osborn). Excited to begin this journey at @i2bcparissaclay.bsky.social @cnrs.fr
The newly announced ERC Synergy Grant includes research on:
✴️ genetic drug design
✴️ the Big Bang's first microseconds
✴️ crowd movement
✴️ nature-society interactions
👉 buff.ly/ZQhLp4h
Congrats to the 66 awarded research teams!
#FrontierResearch
✴️ genetic drug design
✴️ the Big Bang's first microseconds
✴️ crowd movement
✴️ nature-society interactions
👉 buff.ly/ZQhLp4h
Congrats to the 66 awarded research teams!
#FrontierResearch
buff.ly
November 6, 2025 at 11:40 AM
I am very proud to announce that our team has received an ERC synergy grant from @erc.europa.eu. A wonderful recognition of a truly collaborative effort with friends (Julius Lukes, Leos Valasek and Mark Osborn). Excited to begin this journey at @i2bcparissaclay.bsky.social @cnrs.fr
Reposted
#Mifobio2025 - You came home exhausted, but admit it, you already miss #Mifobio 😉
👉 Report by @france3-naquitaine.bsky.social on the @cnrs.fr thematic school organised for 22 years by the #GDRImabio : youtu.be/qDfPJiDmAsM
@cnrsbiologie.bsky.social @cnrsingenierie.bsky.social
👉 Report by @france3-naquitaine.bsky.social on the @cnrs.fr thematic school organised for 22 years by the #GDRImabio : youtu.be/qDfPJiDmAsM
@cnrsbiologie.bsky.social @cnrsingenierie.bsky.social
MIFOBIO 2025 - Reportage FRANCE 3 Nouvelle Aquitaine
YouTube video by GDR Imabio - CNRS
youtu.be
October 19, 2025 at 11:41 PM
#Mifobio2025 - You came home exhausted, but admit it, you already miss #Mifobio 😉
👉 Report by @france3-naquitaine.bsky.social on the @cnrs.fr thematic school organised for 22 years by the #GDRImabio : youtu.be/qDfPJiDmAsM
@cnrsbiologie.bsky.social @cnrsingenierie.bsky.social
👉 Report by @france3-naquitaine.bsky.social on the @cnrs.fr thematic school organised for 22 years by the #GDRImabio : youtu.be/qDfPJiDmAsM
@cnrsbiologie.bsky.social @cnrsingenierie.bsky.social
Reposted
Finally out!
Moderate
POLRMT increase boosts mitochondrial transcription initiation and exercise capacity.
Huge thanks to all co-authors, especially Maria Miranda! @lsajournal.org
@i2bcparissaclay.bsky.social
doi.org/10.26508/lsa...
Moderate
POLRMT increase boosts mitochondrial transcription initiation and exercise capacity.
Huge thanks to all co-authors, especially Maria Miranda! @lsajournal.org
@i2bcparissaclay.bsky.social
doi.org/10.26508/lsa...
POLRMT overexpression increases mtDNA transcription without affecting steady-state mRNA levels
POLRMT is the sole RNA polymerase in human mitochondria, where it generates primers for mitochondrial DNA (mtDNA) replication and transcribes the mtDNA to express genes encoding essential components o...
doi.org
October 18, 2025 at 9:12 AM
Finally out!
Moderate
POLRMT increase boosts mitochondrial transcription initiation and exercise capacity.
Huge thanks to all co-authors, especially Maria Miranda! @lsajournal.org
@i2bcparissaclay.bsky.social
doi.org/10.26508/lsa...
Moderate
POLRMT increase boosts mitochondrial transcription initiation and exercise capacity.
Huge thanks to all co-authors, especially Maria Miranda! @lsajournal.org
@i2bcparissaclay.bsky.social
doi.org/10.26508/lsa...
Reposted
👩🔬J'ai commencé un kit de démarrage "chercheuses en France" go.bsky.app/TBEzKC #FemmesEnScience
J'ai besoin de votre aide pour le remplir et donner de la visibilité aux chercheuses que vous connaissez et qui sont sur Bluesky !
▶️Taguez celles que vous connaissez, je les ajoute !
J'ai besoin de votre aide pour le remplir et donner de la visibilité aux chercheuses que vous connaissez et qui sont sur Bluesky !
▶️Taguez celles que vous connaissez, je les ajoute !
September 23, 2025 at 2:22 PM
👩🔬J'ai commencé un kit de démarrage "chercheuses en France" go.bsky.app/TBEzKC #FemmesEnScience
J'ai besoin de votre aide pour le remplir et donner de la visibilité aux chercheuses que vous connaissez et qui sont sur Bluesky !
▶️Taguez celles que vous connaissez, je les ajoute !
J'ai besoin de votre aide pour le remplir et donner de la visibilité aux chercheuses que vous connaissez et qui sont sur Bluesky !
▶️Taguez celles que vous connaissez, je les ajoute !
Reposted
Great work from a former PhD student of the Minion team @i2bcparissaclay.bsky.social led by @jm-frachisse.bsky.social.
Well done!!!
Well done!!!
The Rapid Mechanically Activated (RMA) channel transduces increases in plasma membrane tension into transient calcium influx https://www.biorxiv.org/content/10.1101/2025.08.06.668926v1
August 7, 2025 at 4:10 PM
Great work from a former PhD student of the Minion team @i2bcparissaclay.bsky.social led by @jm-frachisse.bsky.social.
Well done!!!
Well done!!!
Reposted
Today we had the chance to welcome Cécile Lorrain @ccilelorrain.bsky.social at the I2BC @i2bcparissaclay.bsky.social
Thanks for the great talk and very interesting discussion!
Thanks for the great talk and very interesting discussion!
September 1, 2025 at 3:33 PM
Today we had the chance to welcome Cécile Lorrain @ccilelorrain.bsky.social at the I2BC @i2bcparissaclay.bsky.social
Thanks for the great talk and very interesting discussion!
Thanks for the great talk and very interesting discussion!
Reposted
@cnrs.fr - @cnrsbiologie.bsky.social - @cea.fr - @cea-paris-saclay.bsky.social - @inserm.fr - @inrae-france.bsky.social - @i2bcparissaclay.bsky.social
September 8, 2025 at 6:44 AM
Reposted
Ce projet a été coordonné à l’Institut de biologie intégrative de la cellule (I2BC-CEA/CNRS/Université Paris-Saclay), situé à Gif-sur-Yvette.
@i2bcparissaclay.bsky.social - @cnrsbiologie.bsky.social - @cea-paris-saclay.bsky.social - @cea.fr - @univparissaclay.bsky.social - @inrae-france.bsky.social
@i2bcparissaclay.bsky.social - @cnrsbiologie.bsky.social - @cea-paris-saclay.bsky.social - @cea.fr - @univparissaclay.bsky.social - @inrae-france.bsky.social
September 11, 2025 at 7:33 AM
Ce projet a été coordonné à l’Institut de biologie intégrative de la cellule (I2BC-CEA/CNRS/Université Paris-Saclay), situé à Gif-sur-Yvette.
@i2bcparissaclay.bsky.social - @cnrsbiologie.bsky.social - @cea-paris-saclay.bsky.social - @cea.fr - @univparissaclay.bsky.social - @inrae-france.bsky.social
@i2bcparissaclay.bsky.social - @cnrsbiologie.bsky.social - @cea-paris-saclay.bsky.social - @cea.fr - @univparissaclay.bsky.social - @inrae-france.bsky.social
Reposted
Celebrating the 10 years of the @i2bcparissaclay.bsky.social with an excellent program of talks! Happy birthday I2BC !!🎊 🎂
September 12, 2025 at 7:15 AM
Celebrating the 10 years of the @i2bcparissaclay.bsky.social with an excellent program of talks! Happy birthday I2BC !!🎊 🎂
Reposted
Ready for a week of thinking about DNA's 3rd dimension @biochemsoc.bsky.social's #BioPhyChrom2025. But 1st I'm excited to be hosting @i2bcparissaclay.bsky.social's @vslioy.bsky.social. I am sure her talk on Salmonella chromatin will bring exciting chats & opportunies to @quadraminstitute.bsky.social
September 14, 2025 at 4:05 PM
Ready for a week of thinking about DNA's 3rd dimension @biochemsoc.bsky.social's #BioPhyChrom2025. But 1st I'm excited to be hosting @i2bcparissaclay.bsky.social's @vslioy.bsky.social. I am sure her talk on Salmonella chromatin will bring exciting chats & opportunies to @quadraminstitute.bsky.social
Reposted
📢 À l’occasion de la Fête de la science, le @cnrs.fr organise un jeu-concours pour tenter de remporter des visites insolites au cœur de la recherche, notamment en Essonne. Vous avez jusqu’au 17 septembre pour jouer ! #CNRSinsolite #FDS2024
▶ www.iledefrance-gif.cnrs.fr/fr/evenement...
▶ www.iledefrance-gif.cnrs.fr/fr/evenement...
August 25, 2025 at 1:02 PM
📢 À l’occasion de la Fête de la science, le @cnrs.fr organise un jeu-concours pour tenter de remporter des visites insolites au cœur de la recherche, notamment en Essonne. Vous avez jusqu’au 17 septembre pour jouer ! #CNRSinsolite #FDS2024
▶ www.iledefrance-gif.cnrs.fr/fr/evenement...
▶ www.iledefrance-gif.cnrs.fr/fr/evenement...
Reposted
Our description of the transcriptomic changes during sexual development in #Podospora anserina is out in @genomics.peercommunityin.org ! peercommunityjournal.org/articles/10....
@i2bcparissaclay.bsky.social @univparissaclay.bsky.social
@i2bcparissaclay.bsky.social @univparissaclay.bsky.social
Sexual reproduction is controlled by successive transcriptomic waves in Podospora anserina
peercommunityjournal.org
July 7, 2025 at 5:40 AM
Our description of the transcriptomic changes during sexual development in #Podospora anserina is out in @genomics.peercommunityin.org ! peercommunityjournal.org/articles/10....
@i2bcparissaclay.bsky.social @univparissaclay.bsky.social
@i2bcparissaclay.bsky.social @univparissaclay.bsky.social
Reposted
💼Vous êtes une ou un informaticien spécialisé en système d’exploitation ? Rejoignez le CNRS en tant que technicien support utilisateur/gestion de parc à l’Institut de biologie intégrative de la cellule, à Gif-sur-Yvette (Essonne).
▶ emploi.cnrs.fr/Offres/CDD/U...
▶ emploi.cnrs.fr/Offres/CDD/U...
July 9, 2025 at 7:15 AM
💼Vous êtes une ou un informaticien spécialisé en système d’exploitation ? Rejoignez le CNRS en tant que technicien support utilisateur/gestion de parc à l’Institut de biologie intégrative de la cellule, à Gif-sur-Yvette (Essonne).
▶ emploi.cnrs.fr/Offres/CDD/U...
▶ emploi.cnrs.fr/Offres/CDD/U...
Reposted
Microtubule nucleation: how the NEDD1:MZT1:GCP3 trio captures the γ-TuRC. Clémence Paumier, Cécile Sauvanet, and Benoît Gigant @mikicalab.bsky.social @i2bcparissaclay.bsky.social discuss new work from the @mike-wieczorek.bsky.social lab (rupress.org/jcb/article/...): rupress.org/jcb/article/...
July 22, 2025 at 1:45 PM
Microtubule nucleation: how the NEDD1:MZT1:GCP3 trio captures the γ-TuRC. Clémence Paumier, Cécile Sauvanet, and Benoît Gigant @mikicalab.bsky.social @i2bcparissaclay.bsky.social discuss new work from the @mike-wieczorek.bsky.social lab (rupress.org/jcb/article/...): rupress.org/jcb/article/...
Reposted
Huge thanks to all the co-authors: @mikesleutel.bsky.social and @remaut-lab.bsky.social (from VIB-VUB), Julienne Petit and Anne Marie Wehenkel (from @pasteur.fr @ipdbsc.bsky.social), Nicolas Bayan(from @i2bcparissaclay.bsky.social ) and Daniela Megrian (from @ipmontevideo.bsky.social)
July 30, 2025 at 5:04 AM
Huge thanks to all the co-authors: @mikesleutel.bsky.social and @remaut-lab.bsky.social (from VIB-VUB), Julienne Petit and Anne Marie Wehenkel (from @pasteur.fr @ipdbsc.bsky.social), Nicolas Bayan(from @i2bcparissaclay.bsky.social ) and Daniela Megrian (from @ipmontevideo.bsky.social)
Reposted
The Rapid Mechanically Activated (RMA) channel transduces increases in plasma membrane tension into transient calcium influx https://www.biorxiv.org/content/10.1101/2025.08.06.668926v1
August 7, 2025 at 4:03 PM
The Rapid Mechanically Activated (RMA) channel transduces increases in plasma membrane tension into transient calcium influx https://www.biorxiv.org/content/10.1101/2025.08.06.668926v1
Reposted
Thrilled to see our story now out at @naturecomms.bsky.social
A shared adventure with Estelle Leroy and Mathieu Rougemaille @i2bcparissaclay.bsky.social, and with the precious help of the @palancadelab.bsky.social
Such a tiny RNA with such a wide range of functions
www.nature.com/articles/s41...
A shared adventure with Estelle Leroy and Mathieu Rougemaille @i2bcparissaclay.bsky.social, and with the precious help of the @palancadelab.bsky.social
Such a tiny RNA with such a wide range of functions
www.nature.com/articles/s41...
April 5, 2025 at 10:11 AM
Thrilled to see our story now out at @naturecomms.bsky.social
A shared adventure with Estelle Leroy and Mathieu Rougemaille @i2bcparissaclay.bsky.social, and with the precious help of the @palancadelab.bsky.social
Such a tiny RNA with such a wide range of functions
www.nature.com/articles/s41...
A shared adventure with Estelle Leroy and Mathieu Rougemaille @i2bcparissaclay.bsky.social, and with the precious help of the @palancadelab.bsky.social
Such a tiny RNA with such a wide range of functions
www.nature.com/articles/s41...
Reposted
👋 I'm glad to advertise this new preprint led by the group of Olga Soutourina @i2bcparissaclay.bsky.social including @johann-i2bc.bsky.social - work in collaboration with the Canadian lab of Louis-Charles Fortier and other I2BC members including myself 😊
Check it out ⤵️
Check it out ⤵️
Deciphering the RNA-based regulation mechanism of the phage-encoded AbiF system in Clostridioides difficile https://www.biorxiv.org/content/10.1101/2025.04.15.648962v1
April 18, 2025 at 5:54 AM
👋 I'm glad to advertise this new preprint led by the group of Olga Soutourina @i2bcparissaclay.bsky.social including @johann-i2bc.bsky.social - work in collaboration with the Canadian lab of Louis-Charles Fortier and other I2BC members including myself 😊
Check it out ⤵️
Check it out ⤵️
Reposted
Last @i2bcparissaclay.bsky.social PhD day! I’m happy to discover the work of the future generation of researchers!
May 22, 2025 at 9:14 AM
Last @i2bcparissaclay.bsky.social PhD day! I’m happy to discover the work of the future generation of researchers!
Reposted
A new publication from my lab a great work done with fantastic colleagues from #IGDR (Reynald Gillet’s team for all the cryoem work. pubmed.ncbi.nlm.nih.gov/40187343/
RQC2 is a major player in peptide release from stalled ribosomes - PubMed
Eukaryotic cells prevent the accumulation of potentially toxic aberrant polypeptides and maintain ribosome availability through surveillance and clearance mechanisms, including the evolutionarily cons...
pubmed.ncbi.nlm.nih.gov
April 6, 2025 at 7:41 PM
A new publication from my lab a great work done with fantastic colleagues from #IGDR (Reynald Gillet’s team for all the cryoem work. pubmed.ncbi.nlm.nih.gov/40187343/
Reposted
Congratulations to all the candidates who qualified for the #CNRS #CRCN competition in #Section21. Such brilliant science and incredible enthusiasm! Keep it up!
c3n-cn.fr/2025/01/31/c...
c3n-cn.fr/2025/01/31/c...
Classements d’admissibilité au concours CNRS 2025
Comme en 2021, en 2022, en 2023 et en 2024 la C3N s’engage à rendre publiques les listes des candidates et des candidats admissibles classés par ordre de mérite.
c3n-cn.fr
April 11, 2025 at 7:17 PM
Congratulations to all the candidates who qualified for the #CNRS #CRCN competition in #Section21. Such brilliant science and incredible enthusiasm! Keep it up!
c3n-cn.fr/2025/01/31/c...
c3n-cn.fr/2025/01/31/c...
Reposted
📣 Happy to announce that "DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria" just got published in PNAS www.pnas.org/doi/abs/10.1...
🧬🧶👩🔬👩💻 Collaborative and interdisciplinary work, together with the groups of Ankur Dalia and J. Pablo Radicella
🧬🧶👩🔬👩💻 Collaborative and interdisciplinary work, together with the groups of Ankur Dalia and J. Pablo Radicella
DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria | PNAS
Natural transformation (NT) represents one of the major modes of horizontal gene transfer
in bacterial species. During NT, cells can take up free D...
www.pnas.org
April 14, 2025 at 5:42 AM
📣 Happy to announce that "DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria" just got published in PNAS www.pnas.org/doi/abs/10.1...
🧬🧶👩🔬👩💻 Collaborative and interdisciplinary work, together with the groups of Ankur Dalia and J. Pablo Radicella
🧬🧶👩🔬👩💻 Collaborative and interdisciplinary work, together with the groups of Ankur Dalia and J. Pablo Radicella
Reposted
Happy to see this collaborative study out! A multitasking snoRNA at play in ribosome biogenesis and gametogenesis in fission yeast - project led by Mathieu Rougemaille @i2bcparissaclay.bsky.social and supported by a joint funding from @agencerecherche.bsky.social 🙏 - www.nature.com/articles/s41...
A bifunctional snoRNA with separable activities in guiding rRNA 2’-O-methylation and scaffolding gametogenesis effectors - Nature Communications
Small nucleolar RNAs (snoRNAs) are known for their role in RNA modification to regulate gene expression. Here, the authors identify a snoRNA that not only guides ribosomal RNA 2’- O-methylation but al...
www.nature.com
April 7, 2025 at 7:22 AM
Happy to see this collaborative study out! A multitasking snoRNA at play in ribosome biogenesis and gametogenesis in fission yeast - project led by Mathieu Rougemaille @i2bcparissaclay.bsky.social and supported by a joint funding from @agencerecherche.bsky.social 🙏 - www.nature.com/articles/s41...
Rendez-vous le 20 mai lors du Paris-Saclay Spring à l’École Polytechnique pour échanger sur les recherches et analyses effectuées à l'I2BC dans le domaine de la santé paris-saclay-spring.com
April 8, 2025 at 12:00 PM
Rendez-vous le 20 mai lors du Paris-Saclay Spring à l’École Polytechnique pour échanger sur les recherches et analyses effectuées à l'I2BC dans le domaine de la santé paris-saclay-spring.com