Pierre Grognet
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pierregrognet.bsky.social
Pierre Grognet
@pierregrognet.bsky.social
540 followers 600 following 50 posts
Assistant Professor, MCU HDR, Univ. Paris-Saclay / I2BC
(Epi)genetics, Podospora 🍄
Member of @SFgenetique.bsky.social
Posts Replies Media Videos
Reposted by Pierre Grognet
molbioevol.bsky.social
De Filippo et al. investigated the evolution of recombination suppression in dung fungi, revealing multiple, likely independent evolutionary strata, associated with an extended diploid-like stage in Schizothecium fungi.

🔗 doi.org/10.1093/molbev/msaf325

#evobio #molbio #fungi
Stepwise recombination suppression around the mating-type locus associated with a diploid-like life cycle in Schizothecium fungi
Abstract. Recombination suppression often evolves around sex-determining loci and extends stepwise, resulting in adjacent regions with different levels of
doi.org
January 15, 2026 at 3:20 PM
Reposted by Pierre Grognet
sfp-france.bsky.social
#JJC2026 Eve Mercier (@i2bcparissaclay.bsky.social) on deciphering the #RIP mechanism
January 14, 2026 at 8:52 AM
Reposted by Pierre Grognet
agencerecherche.bsky.social
L’Agence nationale de la recherche (#ANR) est contrainte d’adapter temporairement ses activités dans le cadre des services votés. Le calendrier et la mise en œuvre des appels à projets, dans l’attente de l’adoption de la loi de finances pour 2026, sont précisés dans ce #communiqué ➡ bit.ly/3NyLwbI
January 8, 2026 at 3:49 PM
Reposted by Pierre Grognet
lemonde.fr
Le « Nobel de l’environnement » attribué à une spécialiste des champignons mycorhiziens, invisibles mais fascinants et essentiels à la vie sur Terre
Le « Nobel de l’environnement » attribué à une spécialiste des champignons mycorhiziens, invisibles mais fascinants et essentiels à la vie sur Terre
Toby Kiers, une mycologue et biologiste de l’évolution américaine, agit sur tous les fronts pour attirer l’attention sur l’importance des interactions entre plantes et champignons et la nécessité de protéger cette biodiversité.
www.lemonde.fr
January 14, 2026 at 5:11 AM
Reposted by Pierre Grognet
anne-lopes.bsky.social
Fresh news on de novo genes! Happy to present our latest work published in Nature communications: www.nature.com/articles/s41...

Keywords not in specific order: intergenic ORFs, de novo genes, GC content, foldability, genetic code, ancestral sequence reconstruction and more :)
January 11, 2026 at 7:43 PM
Reposted by Pierre Grognet
nicolashenin.net
Bonjour, afin de contribuer à la présence des institutions sur Bluesky (et leur permettre de faciliter leur exil de X) , j'ai créé ce starterpack des comptes institutionnels nationaux français présents.
January 8, 2026 at 10:10 AM
Reposted by Pierre Grognet
slavi-jan.bsky.social
Beyond excited to see this work finally out in @narjournal.bsky.social! We show that epigenetic modifiers on fungal accessory chromosomes can contribute to the overall epigenetic profile. Many thanks to @gomezlucia93.bsky.social and our other amazing collaborators 👏🏻

academic.oup.com/nar/article/...
Facultative heterochromatin mediated by core and accessory chromosome-encoded H3K27-specific methyltransferases controls virulence in a fungal phytopathogen
Abstract. In many fungal phytopathogens, infection is regulated by accessory genomic regions enriched in facultative heterochromatin, but the precise role
academic.oup.com
January 7, 2026 at 3:39 PM
Reposted by Pierre Grognet
jon276.bsky.social
I’m in this meme and I don’t like it.
#academicsky #academiclife
January 7, 2026 at 8:02 PM
Reposted by Pierre Grognet
bonimenteurfr.bsky.social
Comme quoi, cette chanson des guignols de l'info est intemporelle.
January 3, 2026 at 5:26 PM
Reposted by Pierre Grognet
merriam-webster.com
Take a screenshot of this GIF, and whichever new word you land on is YOUR word for 2026.

Let's. Go.
January 1, 2026 at 3:16 PM
Reposted by Pierre Grognet
liberation.fr
LVMH et Bernard Arnault rachètent les magazines «Challenges», «Sciences et Avenir» et «La Recherche»

Lire ⤵️
LVMH et Bernard Arnault rachètent les magazines «Challenges», «Sciences et Avenir» et «La Recherche»
Les sociétés des journalistes des trois titres ainsi que leurs délégués syndicaux et le comité social et économique (CSE) ont fait part ce mardi de leurs inquiétudes pour l’emploi et l’indépendance éditoriale.
www.liberation.fr
December 30, 2025 at 9:04 PM
Reposted by Pierre Grognet
biorxivpreprint.bsky.social
Pipette, mix, repeat: A reduced-order fluid model and protocol survey to evaluate 96-well mixing protocols https://www.biorxiv.org/content/10.64898/2025.12.27.696695v1
December 30, 2025 at 9:45 PM
Reposted by Pierre Grognet
reporterre.net
Les députés ont rejeté la généralisation du Nutri-score à une courte majorité, malgré la pléthore d'études en sa faveur.

Même la ministre de la Santé s'y était opposée.

Lire l'article ➡️ https://l.reporterre.net/PRt
⏱️ Redif. du 04/12/2025
December 26, 2025 at 8:01 PM
Reposted by Pierre Grognet
biorxivpreprint.bsky.social
CUT&ID for simultaneous profiling of protein-DNA and protein-protein interactions https://www.biorxiv.org/content/10.64898/2025.12.11.693662v1
December 12, 2025 at 11:16 PM
Reposted by Pierre Grognet
loreament.bsky.social
Would you say that Neurospora crassa is declining as a model organism for fungal biology?

💛 No way, that orange fun-guy is alive and well!
🔴 Yeah, not so many people work with it nowadays ...
🔵 Neuro-who?

📅 Ends: December 31, 2025, 10:03 PM UTC

📊 Show results
December 10, 2025 at 9:06 PM
Reposted by Pierre Grognet
france-assos-sante.bsky.social
🔴 Les députés ont rejeté l'affichage obligatoire du #NutriScore... à 3 voix près !

Les Français sont les grands perdants de ce vote :

❌ On les prive d'une information essentielle à laquelle ils ont droit
❌ On les prive d'un outil qui, c'est prouvé, réduit le risque de maladies chroniques
December 4, 2025 at 4:57 PM
Reposted by Pierre Grognet
natmicrobiol.nature.com
Our final issue of 2025 has gone live!

🫁pertussis prevention
🏭pollutants and gut bacteria
🕳️porins and resistance in E. coli
🧬many flavours of CRISPR
🦟fatal fungal attraction

...and more 👇
www.nature.com/nmicrobiol/v...
December 1, 2025 at 6:34 PM
Reposted by Pierre Grognet
lemonde.fr
Ces expressions de la langue française dont on ignore l’origine
Ces expressions de la langue française dont on ignore l’origine
Le dernier dimanche de chaque mois, le service Correction du « Monde » propose sa sélection de curiosités, de trésors et de perles du français. Aujourd’hui, place à ces expressions du quotidien que nous employons sans en connaître l’histoire.
www.lemonde.fr
November 30, 2025 at 4:23 AM
Reposted by Pierre Grognet
ccilelorrain.bsky.social
Our paper on Zymoseptoria tritici 3D genome organization is officially out! @iglavincheska.bsky.social
link.springer.com/article/10.1...
Three-dimensional genome architecture connects chromatin structure and function in a major wheat pathogen - BMC Biology
Background Genome spatial organization plays a fundamental role in biological function across all domains of life. While the principles of nuclear architecture have been well-characterized in animals ...
link.springer.com
November 28, 2025 at 12:43 PM
Reposted by Pierre Grognet
slavi-jan.bsky.social
A couple more days to apply! Join our team as PhD student or technician 👇🏻
slavi-jan.bsky.social Slavica Janevska @slavi-jan.bsky.social · Oct 21
📣 I’m excited to share two open positions in my lab @leibniz-hki.de. For this interdisciplinary project with @luziagyr.bsky.social, I’m seeking (1) an enthusiastic PhD student interested in fungal natural product research and genetic engineering, as well as (2) a technical assistant 👇🏻
November 25, 2025 at 4:49 PM
pierregrognet.bsky.social
Pour connaître les études faites sur les #champignons @univparissaclay.bsky.social
#fungi
www.universite-paris-saclay.fr/actualites/c...
Champignons : lumière sur un règne encore trop méconnu et aux fascinants pouvoirs
Longtemps rapprochés, à tort, des végétaux, les champignons forment un règne extrêmement diversifié dont la majeure partie demeure insoupçonnée. Ces organismes représentent pourtant des modèles passio...
www.universite-paris-saclay.fr
November 24, 2025 at 8:54 PM
Reposted by Pierre Grognet
hercbergs.bsky.social
Pour contrecarrer les lobbies, une pétition a été lancée sur le site de l'Assemblée Nationale "Pour rendre obligatoire l'affichage du Nutri-Score sur les emballages des aliments en France"
Citoyens, consommateurs, signez en nombre et diffusez ! petitions.assemblee-nationale.fr/initiatives/...
Pour rendre obligatoire l'affichage du Nutri-Score sur les emballages des aliments en France - Pour rendre obligatoire l'affichage du Nutri-Score sur les emballages des aliments en France - Platefor...
Le 7 novembre 2025, dans le cadre de la discussion sur le PLFSS à l’Assemblée Nationale, les députés ont adopté deux amendements rendant obligatoire l'affichage du Nutri-Score sur tous les aliments. ...
petitions.assemblee-nationale.fr
November 24, 2025 at 7:52 PM
Reposted by Pierre Grognet
standupforscience.bsky.social
Scientists have been crying "Lysenkoism!" since RFK Jr. took office, but what does it mean? RFK Jr. is reviving a dark chapter of history where ideology trumped evidence, with deadly consequences for millions.

Dissent is patriotic. We're fighting to #impeachrfk
Poster graphic with two half-face photos of Trofim Lysenko and RFK Jr. An arrow points right to invite readers to swipe. Text reads: History doesn't always repeat itself, but it certainly rhymes. American Lysenkoism. A black and white photo of Lysenko inspecting a stalk of grain, with a red semicircle background. text reads: Lysenkoism: Trofim Lysenko was a scientist in the Soviet Union who rejected established genetic and agricultural science in favor or in favour of his own unproven, pseudoscientific ideas. As director of the Institute of Genetics of the Soviet Academy of Sciences, he used his political position to jail dissenters, squash criticism, and fabricate evidence to support his theories. The human cost of his anti-science? Famines that killed millions in the Soviet Union and in China. A picture of RFK Jr in black and white mirroring the previous one of Lysenko. Text reads: Sound familiar? RFK Jr. is happy to exploit the same tactics as Lysenko to carry out his own agenda of deadly anti-science, from firing ACIP experts to demanding that scientists “make the proof” for his claims. We have seen the harms of putting ideology over science. Yet, RFK Jr. wants history to repeat itself. Lysenko put the Soviet Union through famine. RFK Jr.’s anti-vaccine stance and attacks on our public health infrastructure could put the US through outbreak after outbreak of preventable disease.
November 20, 2025 at 3:20 PM
Reposted by Pierre Grognet
paolocrosetto.bsky.social
What is the most profitable industry in the world, this side of the law? Not oil, not IT, not pharma.

It's *scientific publishing*.

We call this the Drain of Scientific Publishing.

Paper: arxiv.org/abs/2511.04820
Background: doi.org/10.1162/qss_...

Thread @markhanson.fediscience.org.ap.brid.gy 👇
November 12, 2025 at 10:31 AM
Reposted by Pierre Grognet
tobybarilbio.bsky.social
TEs aren’t just genomic parasites, they’re also engines of genomic novelty.

Our new study with ~2,000 Z. tritici genomes shows repeated TE mobilization waves during global expansion.

With @danielcroll.bsky.social & @guidopuccetti.bsky.social

🧬 www.nature.com/articles/s41...

#TEworldwide
Historic transposon mobilisation waves create distinct pools of adaptive variants in a major crop pathogen - Nature Communications
In this study, the authors analysed a large genomic dataset to trace how jumping genes shaped the global spread of a major wheat pathogen and reveal bursts of activity over decades that drove adaptati...
www.nature.com
November 12, 2025 at 1:17 PM