Fredrik Hugosson 🇸🇪 in 🇺🇸
fredrikhugosson.bsky.social
Fredrik Hugosson 🇸🇪 in 🇺🇸
@fredrikhugosson.bsky.social
"-I am no evolutionary biologist but.."
PhD. In molecular biology now Evo-Devo using cnidarians.

Know a thing or two about
Cnidarians
Drosophila
Ctenophores

Coffee and Craft beer connoisseur according to friends
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
Notch expression during ctenophore development gives insight into its ancestral function https://www.biorxiv.org/content/10.1101/2025.09.30.679519v1
October 2, 2025 at 10:31 PM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
An updated and spatially validated somatic single-cell atlas of Hydractinia symbiolongicarpus https://www.biorxiv.org/content/10.1101/2025.06.03.657738v1
June 7, 2025 at 4:33 PM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
#drosophila @flybase.bsky.social request emergency funding:
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!

www.philanthropy.cam.ac.uk/give-to-camb...
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
www.philanthropy.cam.ac.uk
June 3, 2025 at 4:15 PM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
The Americans are doing to Kseniia what the Russians did to Brittney Griner for having 0.7 grams of cannabis oil. Except no one is coming to negotiate her freedom and Harvard is sitting on their hands. I am so ashamed. Please share this story.
www.nytimes.com/2025/04/11/s...
She Worked in a Harvard Lab to Reverse Aging, Until ICE Jailed Her (Gift Article)
President Trump’s immigration crackdown ensnared Kseniia Petrova, a scientist who fled Russia after protesting its invasion of Ukraine. She fears arrest if she is deported there.
www.nytimes.com
April 11, 2025 at 5:55 PM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.”
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN
Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...
www.cnn.com
April 9, 2025 at 11:30 AM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
In preprints: the ins and outs of Cnidaria germ layers

Lucas Leclère and Chiara Sinigaglia @chisinig.bsky.social (@cnidevo.bsky.social @biom-banyuls.bsky.social) discuss 3 recent #preprints about the mechanisms that govern germ layer formation in Nematostella vectensis:
doi.org/10.1242/dev....
March 20, 2025 at 10:51 AM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
And... it's live! In situ hybridization has been foundational for sea urchin developmental biology. Here we report a fully automated method to probe more than a hundred genes using a general purpose liquid handler.https://www.biorxiv.org/content/10.1101/2025.03.23.644641v1
March 25, 2025 at 1:48 PM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
In 2008 Mark and I proposed the idea about the relocation of beta-catenin nuclearization and the endomesoderm induction (doi.org/10.1016/j.de...). Now data by @genikhovich.bsky.social et al shows, that beta catenin does not induce endomesoderm in cnidarians. Progress! www.nature.com/articles/s41...
March 13, 2025 at 9:32 AM
Different state, Different lab but still my dear Stella!😍
February 5, 2025 at 12:53 PM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
The Society for Developmental Biology has released a statement on the Unprecedented Disruptions to Biomedical Research in the United States.
January 29, 2025 at 10:08 PM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
Have you ever wanted to *see* receptor activity in embryos? If so, our new preprint is for you! In it, we showcase a new live-cell biosensor for visualizing receptor tyrosine kinase activity in living embryos – pYtags!

www.biorxiv.org/content/10.1...
January 7, 2025 at 5:46 PM
I just bought a suitcase that is larger than any airline will allow as checked back...sigh
January 22, 2025 at 11:44 PM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
January 20, 2025 at 6:00 PM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
An idea for a workshop that you can run (or take yourself!) to teach "R for cell biologists". 🧪
quantixed.org/2025/01/20/g...
Get Better: R for cell biologists – quantixed
quantixed.org
January 20, 2025 at 2:49 PM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
Breaking: Mice aren't humans either!
Scientists have identified functional differences between human and mouse PD-1, which could impact preclinical research on cancer immunotherapies.

Read more in #ScienceImmunology:
Functional differences between rodent and human PD-1 linked to evolutionary divergence
A highly conserved motif in human PD-1 but absent in rodent PD-1 is linked to differential inhibitory activity.
scim.ag
January 11, 2025 at 7:59 PM
A last dance (spawn) for me..and they don't let me down.😍 #Nematostella #Cnidarian #SaturdayInTheLab
January 4, 2025 at 5:03 PM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
Happy New Year!
(my cartoon for @newscientist.bsky.social)
January 1, 2025 at 10:04 AM
Something you unlikely ever see on a craft beer bottle cap. True art both on cap, on bottle and IN the bottle. Christmas in a bottle!
#Noel #brasseriedachouffe
December 24, 2024 at 2:34 PM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
🔥Today's new episode of the Night Science Podcast is super cool: A hypothesis is a liability! We talk about the interplay between hypothesis-driven and exploratory research, and discuss the insights of previous guests of the podcast. I'm really curious to know what you'll think!
December 16, 2024 at 4:58 PM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
Our miRNA story is now in @science.org ! We found a microRNA, not a protein, that finally solved a long-standing evolutionary mystery of wing coloration in butterflies and moths. (1/n)
www.science.org/doi/10.1126/...
A microRNA is the effector gene of a classic evolutionary hotspot locus
In Lepidoptera (butterflies and moths), the genomic region around the gene cortex is a “hotspot” locus, repeatedly implicated in generating intraspecific melanic wing color polymorphisms across 100 mi...
www.science.org
December 5, 2024 at 9:36 PM
Nematostella babies on the way 😍 #cnidarian #morethanonecaninject
December 7, 2024 at 7:56 PM
Reposted by Fredrik Hugosson 🇸🇪 in 🇺🇸
Everyone should read this. It is obcene that a country this weathy does not provide the most basic support for those in need. And what an amazingly talented writer... www.esquire.com/news-politic...
My Life As a Homeless Man in America
An extraordinary firsthand account.
www.esquire.com
November 29, 2024 at 11:09 PM
November 17, 2024 at 11:17 PM
Another day in the lab, pipetting away! #science #enjoythechaos #pipettetips #usascientific
November 13, 2024 at 9:56 PM
Happy Nematostella 😍
#Cnidaria #Nematostella #Embryo
November 11, 2024 at 3:59 PM