Emilie Reas
@etreas.bsky.social
Assistant Professor of Neurosciences @UCSanDiego | Alzheimer's disease & brain aging | (barefoot) running fanatic
Pinned
Emilie Reas
@etreas.bsky.social
· Nov 14
Hi BlueSky! In case we're not already friends, I'm a neuroscientist using neuroimaging (fancy forms of MRI) to understand brain aging and Alzheimer's disease. Also occasionally post about running/sports science. Looking forward to connecting and growing this community! #neuroscience #alzheimers #MRI
Reposted by Emilie Reas
This is 🤯
All publicly available. Looks like an amazing new histology-based human probabilistic atlas and parcellation tool.
#neuroskyence #mri #brainmapping
A probabilistic histological atlas of the human brain for MRI segmentation | Nature share.google/5AD0iW7pxgb4...
All publicly available. Looks like an amazing new histology-based human probabilistic atlas and parcellation tool.
#neuroskyence #mri #brainmapping
A probabilistic histological atlas of the human brain for MRI segmentation | Nature share.google/5AD0iW7pxgb4...
A probabilistic histological atlas of the human brain for MRI segmentation - Nature
NextBrain is an open source, probabilistic atlas of the entire human brain, assembled using artificial-intelligence-enabled registration and segmentation methods to reconstruct the multimodal serial h...
share.google
November 6, 2025 at 5:35 AM
This is 🤯
All publicly available. Looks like an amazing new histology-based human probabilistic atlas and parcellation tool.
#neuroskyence #mri #brainmapping
A probabilistic histological atlas of the human brain for MRI segmentation | Nature share.google/5AD0iW7pxgb4...
All publicly available. Looks like an amazing new histology-based human probabilistic atlas and parcellation tool.
#neuroskyence #mri #brainmapping
A probabilistic histological atlas of the human brain for MRI segmentation | Nature share.google/5AD0iW7pxgb4...
Reposted by Emilie Reas
Here it is: the Trump Administration "draft proposal" to the University of California. Published bc faculty sued for its disclosure.
Its terms go beyond what Trump demands in similar compacts to other universities.
EVERYONE should read: faculty, students, admins, alumni.
ucop.edu/communicatio...
Its terms go beyond what Trump demands in similar compacts to other universities.
EVERYONE should read: faculty, students, admins, alumni.
ucop.edu/communicatio...
ucop.edu
October 25, 2025 at 12:42 AM
Here it is: the Trump Administration "draft proposal" to the University of California. Published bc faculty sued for its disclosure.
Its terms go beyond what Trump demands in similar compacts to other universities.
EVERYONE should read: faculty, students, admins, alumni.
ucop.edu/communicatio...
Its terms go beyond what Trump demands in similar compacts to other universities.
EVERYONE should read: faculty, students, admins, alumni.
ucop.edu/communicatio...
Reposted by Emilie Reas
Wow! This is amazing news. Having friends who are confronted with Huntington's, this brings a ray of hope.
bbc.com/news/article...
bbc.com/news/article...
Huntington's disease successfully treated for first time
One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.
bbc.com
September 24, 2025 at 11:12 PM
Wow! This is amazing news. Having friends who are confronted with Huntington's, this brings a ray of hope.
bbc.com/news/article...
bbc.com/news/article...
Reposted by Emilie Reas
Replenishing the brain’s natural stores of lithium can protect against and even reverse Alzheimer’s disease
go.nature.com/4m8zW3H
go.nature.com/4m8zW3H
New hope for Alzheimer’s: lithium supplement reverses memory loss in mice
Nature - Studies in rodents and humans suggest that low levels of the metal contribute to cognitive decline.
go.nature.com
August 10, 2025 at 9:38 AM
Replenishing the brain’s natural stores of lithium can protect against and even reverse Alzheimer’s disease
go.nature.com/4m8zW3H
go.nature.com/4m8zW3H
Reposted by Emilie Reas
New paper out from the lab, demonstrating a robust non-linear relationship between age at menopause and dementia risk. Fantastic work by post-doc Dr. Ursula Saelzler. alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Age of menopause and dementia risk in 10,832 women from the Swedish Twin Registry
INTRODUCTION
An earlier age of menopause (AOM) is hypothesized to increase vulnerability to the neuropathological processes of dementia, which begin in midlife.
METHODS
We tested this hypothesis i.....
alz-journals.onlinelibrary.wiley.com
August 8, 2025 at 3:48 AM
New paper out from the lab, demonstrating a robust non-linear relationship between age at menopause and dementia risk. Fantastic work by post-doc Dr. Ursula Saelzler. alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Emilie Reas
"Nature has learnt that, as a result, some staff members are screening candidates’ social-media presences to check whether they have expressed negative views about the Trump administration or been involved in diversity, equity and inclusion (DEI) efforts...at their institutions." 🧪
NEW: In an unprecedented move, the NIH will soon disinvite dozens of scientists about to take positions on advisory councils that make final decisions on grant funding.
NIH staff were told to select others aligned with the Trump administration and told to expect placements by political appointees.
NIH staff were told to select others aligned with the Trump administration and told to expect placements by political appointees.
Exclusive: NIH to dismiss dozens of grant reviewers to align with Trump priorities
The move would undo years of work, leaving advisory councils understaffed, and without the full expertise needed for reviews.
www.nature.com
July 14, 2025 at 11:55 PM
"Nature has learnt that, as a result, some staff members are screening candidates’ social-media presences to check whether they have expressed negative views about the Trump administration or been involved in diversity, equity and inclusion (DEI) efforts...at their institutions." 🧪
Reposted by Emilie Reas
The full ruling explaining why NIH grant cuts are illegal came out today.
It's just as blistering as the judge's oral remarks. And it uncovers fresh details in DOGE's role orchestrating the cuts — and on the cuts at Columbia.
Here are my top highlights from the 103-page ruling. 🧵
It's just as blistering as the judge's oral remarks. And it uncovers fresh details in DOGE's role orchestrating the cuts — and on the cuts at Columbia.
Here are my top highlights from the 103-page ruling. 🧵
After ruling the NIH grant cuts were illegal yesterday, Judge Young, a Reagan appointee on the bench since 1985, ended the hearing with a blistering 15-minute speech.
I've cleaned up my notes — here are his remarks in full. 🧵
I've cleaned up my notes — here are his remarks in full. 🧵
Judge rules against NIH grant cuts — and calls them discriminatory
The decision means that the US biomedical agency has to restore funding to hundreds of research projects, but the government will likely appeal.
www.nature.com
July 2, 2025 at 11:55 PM
The full ruling explaining why NIH grant cuts are illegal came out today.
It's just as blistering as the judge's oral remarks. And it uncovers fresh details in DOGE's role orchestrating the cuts — and on the cuts at Columbia.
Here are my top highlights from the 103-page ruling. 🧵
It's just as blistering as the judge's oral remarks. And it uncovers fresh details in DOGE's role orchestrating the cuts — and on the cuts at Columbia.
Here are my top highlights from the 103-page ruling. 🧵
Reposted by Emilie Reas
It seems that only the science community is noticing that NIH and NSF budgets are cut 40% and 55% in the budget bill, respectively. If you live in Maine, West Va, Pennsylvania, Alabama, or Louisiana, CALL YOUR SENATOR as they could make a difference. See below.
prospect.org/politics/202...
prospect.org/politics/202...
Will the Senate Save NIH?
Rescuing biomedical research is every bit as important as saving Medicaid.
prospect.org
June 29, 2025 at 3:17 AM
It seems that only the science community is noticing that NIH and NSF budgets are cut 40% and 55% in the budget bill, respectively. If you live in Maine, West Va, Pennsylvania, Alabama, or Louisiana, CALL YOUR SENATOR as they could make a difference. See below.
prospect.org/politics/202...
prospect.org/politics/202...
Reposted by Emilie Reas
I applied for this trial. This could EASILY have been me. Or someone else you know.
Powerful story from Carolyn Johnson at the Washington Post...
wapo.st/44ntbo4
[Should be a gift link; let me know if there are problems]
wapo.st/44ntbo4
[Should be a gift link; let me know if there are problems]
His custom cancer therapy is in an NIH freezer. He may not get it in time.
The purge of probationary federal workers included skilled lab personnel who would have finalized a customized cell immunotherapy for cancer patients.
wapo.st
June 18, 2025 at 10:07 PM
I applied for this trial. This could EASILY have been me. Or someone else you know.
Judge Young: “This represents racial discrimination and discrimination against America’s LGBTQ community. I would be blind not to call it out ...I’ve been on the bench for 40 years — I’ve never seen government racial discrimination like this.”
A US judge has ordered hundreds of terminated research projects at the US National Institutes of Health to be reinstated, calling the processes that led to their cancellation “bereft of reasoning”.
https://go.nature.com/4kOmXDy
https://go.nature.com/4kOmXDy
Judge rules against NIH grant cuts — and calls them discriminatory
The decision means that the US biomedical agency has to restore funding to hundreds of research projects, but the government will likely appeal.
go.nature.com
June 17, 2025 at 6:57 AM
Judge Young: “This represents racial discrimination and discrimination against America’s LGBTQ community. I would be blind not to call it out ...I’ve been on the bench for 40 years — I’ve never seen government racial discrimination like this.”
Reposted by Emilie Reas
Incredible turn out for #NoKingsDay. Thank you to everyone speaking up and taking action. Dissent is patriotic!
June 15, 2025 at 1:00 AM
Incredible turn out for #NoKingsDay. Thank you to everyone speaking up and taking action. Dissent is patriotic!
Reposted by Emilie Reas
Over the next 25 years, if proposed cuts in NIH funding are made real, “In a population of more than 340 million, this reflects **82 million** fewer years of life.”
In the US alone.
jamanetwork.com/journals/jam...
In the US alone.
jamanetwork.com/journals/jam...
Cutting the NIH—The $8 Trillion Health Care Catastrophe
This JAMA Forum discusses the recent budget cuts to National Institutes of Health (NIH), the effects of these cuts on scientific research and health of individuals in the US, and the prospects for cha...
jamanetwork.com
June 15, 2025 at 1:55 AM
Over the next 25 years, if proposed cuts in NIH funding are made real, “In a population of more than 340 million, this reflects **82 million** fewer years of life.”
In the US alone.
jamanetwork.com/journals/jam...
In the US alone.
jamanetwork.com/journals/jam...
Reposted by Emilie Reas
We heard directly from more than 150 researchers, scientists and investigators about their terminated NIH grants and the science that’s being lost. Full story ⤵️
June 14, 2025 at 1:46 AM
We heard directly from more than 150 researchers, scientists and investigators about their terminated NIH grants and the science that’s being lost. Full story ⤵️
Reposted by Emilie Reas
New paper in Imaging Neuroscience by Emilie T. Reas, Jennifer S. Graves, et al:
Long COVID-related blood-brain barrier breakdown and microstructure in older adults are modified by sex and Alzheimer’s disease genetic risk
doi.org/10.1162/IMAG...
Long COVID-related blood-brain barrier breakdown and microstructure in older adults are modified by sex and Alzheimer’s disease genetic risk
doi.org/10.1162/IMAG...
June 3, 2025 at 10:19 AM
New paper in Imaging Neuroscience by Emilie T. Reas, Jennifer S. Graves, et al:
Long COVID-related blood-brain barrier breakdown and microstructure in older adults are modified by sex and Alzheimer’s disease genetic risk
doi.org/10.1162/IMAG...
Long COVID-related blood-brain barrier breakdown and microstructure in older adults are modified by sex and Alzheimer’s disease genetic risk
doi.org/10.1162/IMAG...
Reposted by Emilie Reas
These are not just grants. This is thousands of people who devoted their lives and careers - taking pay cuts, working long hours, living with uncertainty - all for the chance to try to make people's lives a bit better for you and your loved ones. This breaks my heart.
Cutting NIH or NSF funding sounds abstract. Seeing what research is actually being cut makes it real. Kudos to @nytimes.com for this piece:
www.nytimes.com/interactive/...
www.nytimes.com/interactive/...
Here Are the Nearly 2,500 Medical Research Grants Canceled or Delayed by Trump
Some cuts have been starkly visible, but the country’s medical grant-making machinery has also radically transformed outside the public eye.
www.nytimes.com
June 4, 2025 at 8:20 PM
These are not just grants. This is thousands of people who devoted their lives and careers - taking pay cuts, working long hours, living with uncertainty - all for the chance to try to make people's lives a bit better for you and your loved ones. This breaks my heart.
Reposted by Emilie Reas
Two VA pulmonologists rebuked by Trump administration for warning, in a @nejm.org article, that cancelled contracts, layoffs, and planned staff reductions jeopardize the health of a million veterans seeking help for conditions linked to toxic exposure.
www.theguardian.com/us-news/2025...
www.theguardian.com/us-news/2025...
Exclusive: US veterans agency orders scientists not to publish in journals without clearance
Move that seeks political control of doctors’ and scientists’ published research fits a pattern of censorship by the Trump administration, veterans advocates say
www.theguardian.com
June 1, 2025 at 7:39 PM
Two VA pulmonologists rebuked by Trump administration for warning, in a @nejm.org article, that cancelled contracts, layoffs, and planned staff reductions jeopardize the health of a million veterans seeking help for conditions linked to toxic exposure.
www.theguardian.com/us-news/2025...
www.theguardian.com/us-news/2025...
New work from our postdoc Seraphina Solders shows patterns of blood-brain barrier leakage in cognitively normal APOE4 carriers. BBB breakdown correlated with microstructural brain injury only in groups with high Alzheimer's disease risk (APOE4+, amyloid+, women) www.sciencedirect.com/science/arti...
Blood-brain barrier permeability varies by brain region and APOE4 status and correlates with brain microstructure among high-AD risk groups
Although strong evidence exists for blood–brain barrier (BBB) disruption in Alzheimer’s disease (AD), substantial uncertainty remains regarding its ro…
www.sciencedirect.com
June 2, 2025 at 1:27 AM
New work from our postdoc Seraphina Solders shows patterns of blood-brain barrier leakage in cognitively normal APOE4 carriers. BBB breakdown correlated with microstructural brain injury only in groups with high Alzheimer's disease risk (APOE4+, amyloid+, women) www.sciencedirect.com/science/arti...
Reposted by Emilie Reas
May 31, 2025 at 10:55 PM
Reposted by Emilie Reas
Our annual grantee conference convenes past and current grantees to share insights.
Among today’s presenters:
2021 BIG Award recipients Bradley Olwin, PhD, and Andrey Tsvetkov, PhD.
2022 McKnight Grantees @etreas.bsky.social, and Tara Tracy, PhD.
Check out tomorrow's schedule: ow.ly/KVLf50VZjZq
Among today’s presenters:
2021 BIG Award recipients Bradley Olwin, PhD, and Andrey Tsvetkov, PhD.
2022 McKnight Grantees @etreas.bsky.social, and Tara Tracy, PhD.
Check out tomorrow's schedule: ow.ly/KVLf50VZjZq
May 29, 2025 at 1:44 AM
Our annual grantee conference convenes past and current grantees to share insights.
Among today’s presenters:
2021 BIG Award recipients Bradley Olwin, PhD, and Andrey Tsvetkov, PhD.
2022 McKnight Grantees @etreas.bsky.social, and Tara Tracy, PhD.
Check out tomorrow's schedule: ow.ly/KVLf50VZjZq
Among today’s presenters:
2021 BIG Award recipients Bradley Olwin, PhD, and Andrey Tsvetkov, PhD.
2022 McKnight Grantees @etreas.bsky.social, and Tara Tracy, PhD.
Check out tomorrow's schedule: ow.ly/KVLf50VZjZq
Reposted by Emilie Reas
@scott-delaney.bsky.social has had a front row seat to the Trump admin’s cancellation of NIH grants
I caught up with Scott as his project to track research grant terminations became real personal — and his own funds were cut 🧪
www.statnews.com/2025/05/27/n...
I caught up with Scott as his project to track research grant terminations became real personal — and his own funds were cut 🧪
www.statnews.com/2025/05/27/n...
A Harvard scientist built a database of 2,100 NIH grant terminations. Then his own funding was cut
Harvard's Scott Delaney helped build a database of NIH grant terminations that is being used in litigation against the Trump administration.
www.statnews.com
May 27, 2025 at 1:04 PM
@scott-delaney.bsky.social has had a front row seat to the Trump admin’s cancellation of NIH grants
I caught up with Scott as his project to track research grant terminations became real personal — and his own funds were cut 🧪
www.statnews.com/2025/05/27/n...
I caught up with Scott as his project to track research grant terminations became real personal — and his own funds were cut 🧪
www.statnews.com/2025/05/27/n...
Reposted by Emilie Reas
The myths and fabrications persistently shared by the Health and Human Services Secretary aren’t just disappointing – they’re dangerous. See below for the facts and for our full statement in response to the Secretary’s comments.
❌ FALSE: “For 20 years…we were directing Alzheimer’s research to one hypothesis. And any other hypotheses were shut down.” - Sec. Kennedy
Over the last decade, less than 14% of new National Institutes of Health (NIH) Alzheimer’s projects focused on amyloid beta as the therapeutic target. 🧵(1/4)
Over the last decade, less than 14% of new National Institutes of Health (NIH) Alzheimer’s projects focused on amyloid beta as the therapeutic target. 🧵(1/4)
May 16, 2025 at 4:11 PM
The myths and fabrications persistently shared by the Health and Human Services Secretary aren’t just disappointing – they’re dangerous. See below for the facts and for our full statement in response to the Secretary’s comments.
Reposted by Emilie Reas
Read our full statement calling on Sec. Kennedy to stop spreading harmful Alzheimer’s myths: bit.ly/43dRIKw. 4/4
Contrary to Clear, Verifiable Facts, Secretary Kennedy Continues to Repeat Harmful Myths About Alzheimer’s and Dementia Research
The Alzheimer's Association calls on HHS Secretary Kennedy to stop dangerous fabrications about the state of Alzheimer’s and dementia research.
bit.ly
May 15, 2025 at 8:23 PM
Read our full statement calling on Sec. Kennedy to stop spreading harmful Alzheimer’s myths: bit.ly/43dRIKw. 4/4
Reposted by Emilie Reas
Since this was published yesterday, NPR reports JAMA joins NEJM on the list of journals that confirms they’ve been sent threatening letters by Trump’s DOJ, ominously referencing their tax-exempt status in a bid to compel regime-friendly editorial choices.
www.scientificamerican.com/article/the-...
www.scientificamerican.com/article/the-...
The Scary Implications of U.S. Government Attacks on Medical Journals
A Trump-aligned prosecutor’s attack on medical journals is a threat to your health care—and the medical establishment should not comply
www.scientificamerican.com
May 2, 2025 at 10:10 PM
Since this was published yesterday, NPR reports JAMA joins NEJM on the list of journals that confirms they’ve been sent threatening letters by Trump’s DOJ, ominously referencing their tax-exempt status in a bid to compel regime-friendly editorial choices.
www.scientificamerican.com/article/the-...
www.scientificamerican.com/article/the-...
Reposted by Emilie Reas
Why do women experience Alzheimer's disease at twice the rate of men? It might be genetic, hormonal, social, cultural, or most likely multifactorial. This is just one of many questions that urgently demands ongoing support for biomedical research on sex/gender health. www.nature.com/articles/d41...
Why women experience Alzheimer’s disease differently from men
Sex and gender research could lead to better, more equitable treatments — if it is allowed to continue without political interference.
www.nature.com
April 23, 2025 at 6:21 AM
Why do women experience Alzheimer's disease at twice the rate of men? It might be genetic, hormonal, social, cultural, or most likely multifactorial. This is just one of many questions that urgently demands ongoing support for biomedical research on sex/gender health. www.nature.com/articles/d41...