Matthew Panizzon
banner
matthewpanizzon.bsky.social
Matthew Panizzon
@matthewpanizzon.bsky.social
Associate Professor at UC San Diego; PI of the VETSA project; Cognitive Aging, Alzheimer's Disease, Sex Differences, and Genetics; Tired Father.
Reposted by Matthew Panizzon
Check out our data! Please reach out if you're interested, we're happy to provide more info and we may have useful datasets (e.g., with extra cleaning or composite variables) to address specific questions. Raw and derived MRI data also available upon request for ~1/2 the cohort.
🚨NEW DATA RELEASE🚨

Data from VETSA waves 1-3 is now available for public download from NACDA! This includes cognitive, health, psychosocial and demographic info from our nationwide twin cohort. Future releases will include wave 4 data and derived MRI variables.
www.icpsr.umich.edu/web/ICPSR/st...
Vietnam Era Twin Study of Aging (VETSA), United States, 2002-2019
www.icpsr.umich.edu
September 26, 2025 at 3:28 PM
Congratulations! So well deserved.
August 9, 2025 at 1:39 AM
New paper out from the lab, demonstrating a robust non-linear relationship between age at menopause and dementia risk. Fantastic work by post-doc Dr. Ursula Saelzler. alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Age of menopause and dementia risk in 10,832 women from the Swedish Twin Registry
INTRODUCTION An earlier age of menopause (AOM) is hypothesized to increase vulnerability to the neuropathological processes of dementia, which begin in midlife. METHODS We tested this hypothesis i.....
alz-journals.onlinelibrary.wiley.com
August 8, 2025 at 3:48 AM
Reposted by Matthew Panizzon
Happy to share a new published study link.springer.com/article/10.1...
on subjective memory concern, negative affect, and cortical microstructure using @vetsa.bsky.social dataset and supported by a K01 grant from the NIA!
link.springer.com
July 22, 2025 at 10:49 PM
Reposted by Matthew Panizzon
Study by Alex Posis finding that TBI is associated with altered microstructure of certain WM tracts that may persist at least 4 decades after the injury.

www.sciencedirect.com/science/arti...
Associations of history of traumatic brain injury with markers of brain health among older men in the Vietnam Era Twin Study of Aging
Traumatic brain injury (TBI) is associated with increased risk of dementia, but it is unclear how earlier life TBI is related to brain health in older…
www.sciencedirect.com
July 22, 2025 at 10:56 PM
Reposted by Matthew Panizzon
Study from Nathan Gillespie testing causal associations of plasma amyloid on total tau using #VETSA twin data.
www.sciencedirect.com/science/arti...
Testing the causal impact of plasma amyloid on total Tau using a genetically informative sample of adult male twins
The amyloid cascade hypothesis predicts that amyloid-beta (Aβ) aggregation drives tau tangle accumulation. We tested competing causal and non-causal h…
www.sciencedirect.com
July 22, 2025 at 11:05 PM
Reposted by Matthew Panizzon
I was fortunate enough to be interviewed by the Karen Toffler Charitable Trust on their Research Renaissance podcast! I talk about sex differences in Alzheimer's disease risk and optimizing women's brain health.

A link for those interested: open.spotify.com/episode/3ou4...
Unlocking Sex-Based Differences in Alzheimer’s Risk with Dr. Rachel Buckley
Research Renaissance: Exploring the Future of Brain Science · Episode
open.spotify.com
July 16, 2025 at 4:25 PM
Reposted by Matthew Panizzon
On Monday, Ann S. Bowers WBHI Director Emily Jacobs, PhD, testified for AB-432, California’s Menopause Care Equity Act. Updates are coming soon! More info about AB-432 here: bit.ly/ab-432menopa... #womenshealth #brainhealth
July 8, 2025 at 9:06 PM
Reposted by Matthew Panizzon
Trying to create directory tree for a new project or storage location? I did, but couldn't find an app that did exactly what I wanted, so I had GitHub Copilot + Claude create an app for me.

Link to the web app: jelman.github.io/TreeForge/
July 9, 2025 at 9:12 PM
Reposted by Matthew Panizzon
A new paper is out from our work with the Million Veteran Program (MVP). A ancestry specific GWAS of androgen levels in men. www.nature.com/articles/s41...
Discovery of novel ancestry specific genes for androgens and hypogonadism in Million Veteran Program Men - Nature Communications
Here, the authors perform a genome-wide association study to identify 157 significant testosterone genetic variants in male veterans, of which 8 are ancestry-specific. Men with higher testosterone gen...
www.nature.com
May 2, 2025 at 8:00 PM
Great post-doc opportunity at the University of Southern California working with a fantastic group of researchers. If you are interested in twin studies, aging, and health disparities you should check this out. dornsife.usc.edu/cesr/igems/
IGEMS: The Interplay of Genes and Environment across Multiple Studies - Center for Economic and Social Research
The Interplay of Genes and Environment across Multiple Studies (IGEMS) consortium is a collaboration involving over fifteen longitudinal twin studies of adult development and aging. Funding is from Na...
dornsife.usc.edu
April 3, 2025 at 5:07 PM
Reposted by Matthew Panizzon
Thank you, Scott Peters!

We appreciate you!

scottpeters.house.gov/2025/3/rep-p...
Rep. Peters Announces NIH Funded Alzheimer’s Researcher as State of the Union Guest
Congressman Scott Peters
scottpeters.house.gov
March 4, 2025 at 1:44 PM
Reposted by Matthew Panizzon
Please take two minutes to watch this excellent video that explains WHY SEX DIFFERENCES are critical to study...

This is why PINK Concussions has spent the last 12 years advocating for women to be included in Brain Injury research and why we will not give up advocating!

youtu.be/iyMmkoKEoLI?...
A New Vision for Women's Health Research
YouTube video by The National Academies of Sciences, Engineering, and Medicine
youtu.be
February 26, 2025 at 7:26 PM
Reposted by Matthew Panizzon
Hit the paywall- anyone at UCSD w/ more insight into the $200M projection? NIH indirect-related, NSF, USAID, DEI-related, other?
@jaredwyoung.bsky.social @michaeltaffe.bsky.social

www.sandiegouniontribune.com/2025/02/20/u...
UC San Diego, bracing for more than $200M in funding cuts, freezes faculty hiring
‘This is the biggest financial challenge in UCSD’s history,’ said Terry Gaasterland, a longtime faculty member.
www.sandiegouniontribune.com
February 21, 2025 at 3:38 AM
Reposted by Matthew Panizzon
Advancing Inclusive AI in Women’s Brain Health 🧠✨

We are thrilled to announce a $1.5M award from the Chan Zuckerberg Initiative to support the Women’s Brain Health Initiative in advancing inclusive AI through multi-modal biomedical datasets.
February 4, 2025 at 1:22 AM
Reposted by Matthew Panizzon
Anyone who downplays the threat of the anti-vaccine movement is either not paying attention or has been bamboozled.

Sadly, many of us have been warning about their pseudoscientific assault on public health for years.

www.nature.com/articles/d41...
January 24, 2025 at 2:28 AM
There's a new paper out in the Journal of Alzheimer's Disease of the curation of dementia data in the Million Veteran Program. Proud to be part of the effort lead by Mark Logue at Boston University and Victoria Merritt at UC San Diego.
doi.org/10.1177/1387...
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
doi.org
December 18, 2024 at 4:53 PM
Reposted by Matthew Panizzon
Here's a starter pack of researchers studying the effects of hormones on the brain with #neuroimaging. Thanks to @sheilashanmugan.bsky.social @angielaird.bsky.social @62442katieb.bsky.social and Laura Pritschet for filling it in. If you want to be added, just reply to this post and I'll add you.
December 3, 2024 at 3:17 PM
Reposted by Matthew Panizzon
New article describing a regional parcellation scheme of abnormal white matter developed using #VETSA data!
New article led by @cfnote.bsky.social and Shu-Ju Lin describing a novel parcellation of abnormal white matter w/ 5 distinct regions. Twin models identified common & unique genetic and environmental influences that may reflect variable underlying etiologies.
onlinelibrary.wiley.com/doi/10.1002/...
December 6, 2024 at 4:39 PM
Come and work with us!
December 6, 2024 at 5:12 PM
Reposted by Matthew Panizzon
Million Veteran Program & FinnGen teams are pleased to release v1 meta-analysis of MVP, FinnGen and UKBB GWAS data. This first version includes ~300 binary disease definitions across >1.5 M individuals.
Browse scans at: mvp-ukbb.finngen.fi
December 5, 2024 at 12:53 PM
New preprint from the Panizzon Lab looking at age of menopause and dementia risk in the Swedish Twin Registry. Fantastic work by the social media averse Ursula Saelzler.

www.medrxiv.org/content/10.1...
Age of menopause and dementia risk in 10,832 women from the Swedish Twin Registry
INTRODUCTION An earlier age of menopause (AOM) is hypothesized to increase vulnerability to the neuropathological processes of dementia which begin in midlife. METHODS We tested this hypothesis in a ...
www.medrxiv.org
December 4, 2024 at 4:13 PM
Fascinating article in The NY Times. If you are interested in women's health and the long-term consequences of "standard" medical care, you should take a look. www.nytimes.com/2024/12/02/h...
So You’ve Had a Hysterectomy. Do You Know What Was Removed?
Patients often are in the dark about which organs remain and which were removed — particularly the ovaries, which profoundly influence lifelong health.
www.nytimes.com
December 3, 2024 at 1:40 AM
Reposted by Matthew Panizzon
Only 0.5% of neuroscience research focuses on issues exclusive to the female body. Let’s be the change. 🧠💪
November 21, 2024 at 2:22 AM