FinnGen
@finngen.bsky.social
A forerunner in the global landscape of genomics research projects. The study has collected and analysed genome and health data from >500,000 Finnish biobank donors to understand the genetic basis of diseases.
www.finngen.fi
www.finngen.fi
The largest genetic study of anxiety disorders to date has identified 58 genetic variants associated with anxiety. The research, published in Nature Genetics, was based on data from >120,000 individuals with anxiety disorders, from various cohorts, including FinnGen.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
February 9, 2026 at 2:38 PM
The largest genetic study of anxiety disorders to date has identified 58 genetic variants associated with anxiety. The research, published in Nature Genetics, was based on data from >120,000 individuals with anxiety disorders, from various cohorts, including FinnGen.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by FinnGen
🌍 On #WorldCancerDay we recognise those in the BBMRI-ERIC community working to advance cancer research.
🔬 In our first post, we looked at EU projects. Let's turn the spotlight on the researchers & biobankers driving cancer innovation - The teams behind the data, discoveries & breakthroughs.
🧵 1/2
🔬 In our first post, we looked at EU projects. Let's turn the spotlight on the researchers & biobankers driving cancer innovation - The teams behind the data, discoveries & breakthroughs.
🧵 1/2
February 4, 2026 at 2:00 PM
🌍 On #WorldCancerDay we recognise those in the BBMRI-ERIC community working to advance cancer research.
🔬 In our first post, we looked at EU projects. Let's turn the spotlight on the researchers & biobankers driving cancer innovation - The teams behind the data, discoveries & breakthroughs.
🧵 1/2
🔬 In our first post, we looked at EU projects. Let's turn the spotlight on the researchers & biobankers driving cancer innovation - The teams behind the data, discoveries & breakthroughs.
🧵 1/2
FinnGenin suomalaisten partnerien edustajat tapasivat eilen Biomedicumissa Helsingissä ja etäyhteyden välityksellä. Kiitos kaikille osallistujille aktiivisuudesta tutkimuksen seuraavan vaiheen suunnittelussa!
February 4, 2026 at 11:12 AM
FinnGenin suomalaisten partnerien edustajat tapasivat eilen Biomedicumissa Helsingissä ja etäyhteyden välityksellä. Kiitos kaikille osallistujille aktiivisuudesta tutkimuksen seuraavan vaiheen suunnittelussa!
This week, Aarno Palotie and Mark Daly are visiting our Finnish partner organisations presenting what FinnGen has achieved and discussing how to develop it in the future. Great that the seminars, organised with help from the analysts that support FinnGen locally, have turned out to be popular!
January 29, 2026 at 2:25 PM
This week, Aarno Palotie and Mark Daly are visiting our Finnish partner organisations presenting what FinnGen has achieved and discussing how to develop it in the future. Great that the seminars, organised with help from the analysts that support FinnGen locally, have turned out to be popular!
We've been contributing to an international study identifying 13 genetic markers associated with infection with the Omicron variant of the coronavirus. The study, led by Statens Serum Institut, was recently published in Nature Genetics:
🔗 www.nature.com/articles/s41...
🔗 en.ssi.dk/news/news/20...
🔗 www.nature.com/articles/s41...
🔗 en.ssi.dk/news/news/20...
New study finds distinct genetic risk factors for infection with the Omicron variant of the coronavirus
Genetic differences may influence the risk of infection with the highly transmissible Omicron variant, and the patterns differ from earlier coronavirus variants, according to a new large international...
en.ssi.dk
January 29, 2026 at 9:20 AM
We've been contributing to an international study identifying 13 genetic markers associated with infection with the Omicron variant of the coronavirus. The study, led by Statens Serum Institut, was recently published in Nature Genetics:
🔗 www.nature.com/articles/s41...
🔗 en.ssi.dk/news/news/20...
🔗 www.nature.com/articles/s41...
🔗 en.ssi.dk/news/news/20...
Reposted by FinnGen
New preprint 👇
Does diagnostic misclassification in EHR-based psychiatry GWAS suppress genetic discovery?
We use simulations and FinnGen data to expand the SuperControl framework and propose a new ML approach (PRISMA) to boost signal discovery.
Led by Lisa Eick & Zhiyu Yang!
Does diagnostic misclassification in EHR-based psychiatry GWAS suppress genetic discovery?
We use simulations and FinnGen data to expand the SuperControl framework and propose a new ML approach (PRISMA) to boost signal discovery.
Led by Lisa Eick & Zhiyu Yang!
December 29, 2025 at 2:51 PM
New preprint 👇
Does diagnostic misclassification in EHR-based psychiatry GWAS suppress genetic discovery?
We use simulations and FinnGen data to expand the SuperControl framework and propose a new ML approach (PRISMA) to boost signal discovery.
Led by Lisa Eick & Zhiyu Yang!
Does diagnostic misclassification in EHR-based psychiatry GWAS suppress genetic discovery?
We use simulations and FinnGen data to expand the SuperControl framework and propose a new ML approach (PRISMA) to boost signal discovery.
Led by Lisa Eick & Zhiyu Yang!
On behalf of all of us in FinnGen team, we wish you Happy Holidays and a wonderful New Year full of exciting scientific discoveries!
Thank you for being part of the FinnGen community and for helping move this effort forward together. 🧬❄️
Thank you for being part of the FinnGen community and for helping move this effort forward together. 🧬❄️
December 22, 2025 at 9:47 AM
On behalf of all of us in FinnGen team, we wish you Happy Holidays and a wonderful New Year full of exciting scientific discoveries!
Thank you for being part of the FinnGen community and for helping move this effort forward together. 🧬❄️
Thank you for being part of the FinnGen community and for helping move this effort forward together. 🧬❄️
Kindly note that the URLs for our publicly available meta-analysis result browsers have been updated.
The browsers are now accessible at:
➡️FinnGen + pan-UKBB meta-analysis results: public-metaresults-fg-ukbb.finngen.fi
➡️FinnGen-MVP-UKBB meta-analysis results: public-mvp-ukbb.finngen.fi
The browsers are now accessible at:
➡️FinnGen + pan-UKBB meta-analysis results: public-metaresults-fg-ukbb.finngen.fi
➡️FinnGen-MVP-UKBB meta-analysis results: public-mvp-ukbb.finngen.fi
Million Veteran Program & FinnGen teams are pleased to release v1 meta-analysis of MVP, FinnGen and UKBB GWAS data. This first version includes ~300 binary disease definitions across >1.5 M individuals.
Browse scans at: mvp-ukbb.finngen.fi
Browse scans at: mvp-ukbb.finngen.fi
December 22, 2025 at 9:16 AM
Kindly note that the URLs for our publicly available meta-analysis result browsers have been updated.
The browsers are now accessible at:
➡️FinnGen + pan-UKBB meta-analysis results: public-metaresults-fg-ukbb.finngen.fi
➡️FinnGen-MVP-UKBB meta-analysis results: public-mvp-ukbb.finngen.fi
The browsers are now accessible at:
➡️FinnGen + pan-UKBB meta-analysis results: public-metaresults-fg-ukbb.finngen.fi
➡️FinnGen-MVP-UKBB meta-analysis results: public-mvp-ukbb.finngen.fi
Autumn semester publication wrap-up! 📄
This autumn, FinnGen researchers contributed to a remarkable set of papers across human genetics, medicine, and methods; spanning @natgenet.nature.com, @natcomms.nature.com, Hypertension, @ajhgnews.bsky.social and more.
Here’s a 🧵 highlighting these studies ⬇️
This autumn, FinnGen researchers contributed to a remarkable set of papers across human genetics, medicine, and methods; spanning @natgenet.nature.com, @natcomms.nature.com, Hypertension, @ajhgnews.bsky.social and more.
Here’s a 🧵 highlighting these studies ⬇️
December 19, 2025 at 12:47 PM
Autumn semester publication wrap-up! 📄
This autumn, FinnGen researchers contributed to a remarkable set of papers across human genetics, medicine, and methods; spanning @natgenet.nature.com, @natcomms.nature.com, Hypertension, @ajhgnews.bsky.social and more.
Here’s a 🧵 highlighting these studies ⬇️
This autumn, FinnGen researchers contributed to a remarkable set of papers across human genetics, medicine, and methods; spanning @natgenet.nature.com, @natcomms.nature.com, Hypertension, @ajhgnews.bsky.social and more.
Here’s a 🧵 highlighting these studies ⬇️
We are looking for a Software Developer to join our international team in Finland! With us, you will gain invaluable experience in high-impact software solutions that empower researchers to analyse and visualise extensive genomic and health data. Apply by 30 Jan:
jobs.helsinki.fi/job/Helsinki...
jobs.helsinki.fi/job/Helsinki...
December 10, 2025 at 11:30 AM
We are looking for a Software Developer to join our international team in Finland! With us, you will gain invaluable experience in high-impact software solutions that empower researchers to analyse and visualise extensive genomic and health data. Apply by 30 Jan:
jobs.helsinki.fi/job/Helsinki...
jobs.helsinki.fi/job/Helsinki...
Reposted by FinnGen
Excited to share our new FinnGen single-nucleus multiome preprint! 🧬
We profiled ~10M PBMCs (snRNA-seq + snATAC-seq) from 1,108 Finnish donors to map how genetic variants drive complex disease through chromatin and gene regulation 🧵👇
🔗 Link: www.medrxiv.org/content/10.1...
We profiled ~10M PBMCs (snRNA-seq + snATAC-seq) from 1,108 Finnish donors to map how genetic variants drive complex disease through chromatin and gene regulation 🧵👇
🔗 Link: www.medrxiv.org/content/10.1...
December 1, 2025 at 3:36 PM
Excited to share our new FinnGen single-nucleus multiome preprint! 🧬
We profiled ~10M PBMCs (snRNA-seq + snATAC-seq) from 1,108 Finnish donors to map how genetic variants drive complex disease through chromatin and gene regulation 🧵👇
🔗 Link: www.medrxiv.org/content/10.1...
We profiled ~10M PBMCs (snRNA-seq + snATAC-seq) from 1,108 Finnish donors to map how genetic variants drive complex disease through chromatin and gene regulation 🧵👇
🔗 Link: www.medrxiv.org/content/10.1...
Researchers from the University of Edinburgh carried out the largest genetic analysis of delirium to date, drawing on data from several study cohorts, including FinnGen.
The results demonstrate that APOE contributes to delirium susceptibility independently of dementia.
www.ed.ac.uk/news/study-f...
The results demonstrate that APOE contributes to delirium susceptibility independently of dementia.
www.ed.ac.uk/news/study-f...
Study finds gene linked with risk of delirium | News | The University of Edinburgh
A major genetic risk factor for delirium has been identified in a landmark study that analysed the DNA of more than one million people worldwide.
www.ed.ac.uk
November 27, 2025 at 9:09 AM
Researchers from the University of Edinburgh carried out the largest genetic analysis of delirium to date, drawing on data from several study cohorts, including FinnGen.
The results demonstrate that APOE contributes to delirium susceptibility independently of dementia.
www.ed.ac.uk/news/study-f...
The results demonstrate that APOE contributes to delirium susceptibility independently of dementia.
www.ed.ac.uk/news/study-f...
In a new study, @hheyne.bsky.social and her team identified a Finnish-enriched missense variant in the SCN5A gene that acts like a natural lifelong cardiac sodium channel blockade, decreasing the risk of cardiac arrhythmias while also having some negative effects.
hpi.de/en/article/h...
hpi.de/en/article/h...
HPI study finds advances in the treatment of heart disease
HPI researchers Dr. Henrike Heyne, Julian Wanner and their team discover gene variant that acts like heart medication. Their study has now been published.
hpi.de
November 26, 2025 at 9:43 AM
In a new study, @hheyne.bsky.social and her team identified a Finnish-enriched missense variant in the SCN5A gene that acts like a natural lifelong cardiac sodium channel blockade, decreasing the risk of cardiac arrhythmias while also having some negative effects.
hpi.de/en/article/h...
hpi.de/en/article/h...
Reposted by FinnGen
Check out our new article in #Circulation on an astonishing genetic variant in the ion channel #SCN5A that enables us to learn about #cardiac-arrhythmia and their treatment with sodium channel blockers.
@finngen.bsky.social
www.ahajournals.org/doi/10.1161/...
Congrats to @jwanner.bsky.social
@finngen.bsky.social
www.ahajournals.org/doi/10.1161/...
Congrats to @jwanner.bsky.social
Leveraging a Genetic Proxy to Investigate the Effects of Lifelong Cardiac Sodium Channel Blockade | Circulation
BACKGROUND: Atrial fibrillation and other cardiac arrhythmias pose a major public health burden,
but prevention remains difficult. We investigated a genetic variant that we found
to act like a natural...
www.ahajournals.org
November 24, 2025 at 1:05 PM
Check out our new article in #Circulation on an astonishing genetic variant in the ion channel #SCN5A that enables us to learn about #cardiac-arrhythmia and their treatment with sodium channel blockers.
@finngen.bsky.social
www.ahajournals.org/doi/10.1161/...
Congrats to @jwanner.bsky.social
@finngen.bsky.social
www.ahajournals.org/doi/10.1161/...
Congrats to @jwanner.bsky.social
Depression in young adulthood has a stronger hereditary component and is associated with a higher risk of suicide attempts than depression that begins later in life, according to a new study led by researchers @ki.se, including FinnGen as one of the study cohorts:
news.ki.se/genes-may-pr...
news.ki.se/genes-may-pr...
Genes may predict suicide risk in depression
Depression in young adulthood has a stronger hereditary component and is associated with a higher risk of suicide attempts than depression that begins later in life, according to a new study published...
news.ki.se
November 20, 2025 at 1:01 PM
Depression in young adulthood has a stronger hereditary component and is associated with a higher risk of suicide attempts than depression that begins later in life, according to a new study led by researchers @ki.se, including FinnGen as one of the study cohorts:
news.ki.se/genes-may-pr...
news.ki.se/genes-may-pr...
We are proud to welcome Alnylam Pharmaceuticals as the 15th pharma company to join our public-private partnership! Alnylam brings world-leading expertise in RNAi therapeutics to the consortium, further enriching the scientific and translational potential of the study. www.finngen.fi/en/alnylam-b...
Alnylam Becomes Newest Partner in FinnGen Consortium | FinnGen
FinnGen is proud to welcome Alnylam Pharmaceuticals as its newest industry partner. As the 15th pharmaceutical company to join the public-private partnership, Alnylam brings world-leading expertise in...
www.finngen.fi
November 12, 2025 at 1:01 PM
We are proud to welcome Alnylam Pharmaceuticals as the 15th pharma company to join our public-private partnership! Alnylam brings world-leading expertise in RNAi therapeutics to the consortium, further enriching the scientific and translational potential of the study. www.finngen.fi/en/alnylam-b...
FinnGen-aineistoa hyödyntänyt LL Joel Räsäsen normaalipaineisen hydrokefalian eli NPH-taudin geneettistä taustaa käsittelevä väitöskirja tarkastetaan tänään Itä-Suomen yliopiston terveystieteiden tiedekunnassa Kuopion kampuksella. Tilaisuutta voi seurata myös verkossa:
www.uef.fi/fi/artikkeli...
www.uef.fi/fi/artikkeli...
LL Joel Räsänen, väitös 31.10.2025: Uusi tieto NPH-taudin geneettisestä taustasta voi auttaa valottamaan taudin syntymekanismeja
NPH-taudin genominlaajuinen tutkimus on ensimmäinen laatuaan maailmassa ja sen tulokset tarjoavat merkittävästi uutta tietoa taudin geneettisistä tekijöistä.
www.uef.fi
October 31, 2025 at 8:53 AM
FinnGen-aineistoa hyödyntänyt LL Joel Räsäsen normaalipaineisen hydrokefalian eli NPH-taudin geneettistä taustaa käsittelevä väitöskirja tarkastetaan tänään Itä-Suomen yliopiston terveystieteiden tiedekunnassa Kuopion kampuksella. Tilaisuutta voi seurata myös verkossa:
www.uef.fi/fi/artikkeli...
www.uef.fi/fi/artikkeli...
Reposted by FinnGen
Comment🚨
Large biobank projects like #FinnGen help in uncovering genetic factors that influence cancer risk and outcomes, enhancing risk prediction & biomarker and drug target discovery.
@finngen.bsky.social @dalygene.bsky.social @aoxing2.bsky.social
📖 👇
Large biobank projects like #FinnGen help in uncovering genetic factors that influence cancer risk and outcomes, enhancing risk prediction & biomarker and drug target discovery.
@finngen.bsky.social @dalygene.bsky.social @aoxing2.bsky.social
📖 👇
Unlocking the potential of FinnGen to advance cancer research - Nature Reviews Cancer
Large biobank projects such as FinnGen have enabled systematic searches for inherited factors that causally influence a wide range of human traits, including cancer risk and outcome. These explorations provide genetic insights for various aspects of cancer research, including improved risk prediction, enhanced biomarker and drug target discovery, and personalized medicine.
bit.ly
October 20, 2025 at 3:01 PM
Comment🚨
Large biobank projects like #FinnGen help in uncovering genetic factors that influence cancer risk and outcomes, enhancing risk prediction & biomarker and drug target discovery.
@finngen.bsky.social @dalygene.bsky.social @aoxing2.bsky.social
📖 👇
Large biobank projects like #FinnGen help in uncovering genetic factors that influence cancer risk and outcomes, enhancing risk prediction & biomarker and drug target discovery.
@finngen.bsky.social @dalygene.bsky.social @aoxing2.bsky.social
📖 👇
If you are in or around Turku tomorrow, don’t miss Prof. Mark Daly’s @biocityturku.bsky.social guest seminar highlighting the latest FinnGen discoveries!
📆21st Oct at 12:00-13:00, Presidentti auditorium, BioCity
Title: FinnGen and the road ahead in human genetics
🔗 biocityturku.fi/events/bioci...
📆21st Oct at 12:00-13:00, Presidentti auditorium, BioCity
Title: FinnGen and the road ahead in human genetics
🔗 biocityturku.fi/events/bioci...
October 20, 2025 at 9:19 AM
If you are in or around Turku tomorrow, don’t miss Prof. Mark Daly’s @biocityturku.bsky.social guest seminar highlighting the latest FinnGen discoveries!
📆21st Oct at 12:00-13:00, Presidentti auditorium, BioCity
Title: FinnGen and the road ahead in human genetics
🔗 biocityturku.fi/events/bioci...
📆21st Oct at 12:00-13:00, Presidentti auditorium, BioCity
Title: FinnGen and the road ahead in human genetics
🔗 biocityturku.fi/events/bioci...
Day 4 at #ASHG2025 and the FinnGen team is still going strong! 💪🧬
Visit today’s FinnGen posters (see the thread) and swing by booth #147 for some Finnish candies and great conversation!
Visit today’s FinnGen posters (see the thread) and swing by booth #147 for some Finnish candies and great conversation!
October 17, 2025 at 6:31 PM
Day 4 at #ASHG2025 and the FinnGen team is still going strong! 💪🧬
Visit today’s FinnGen posters (see the thread) and swing by booth #147 for some Finnish candies and great conversation!
Visit today’s FinnGen posters (see the thread) and swing by booth #147 for some Finnish candies and great conversation!
Reposted by FinnGen
Excited (😁) to share a commentary on @finngen.bsky.social & cancer research, co-written with Mervi Aavikko & @dalygene.bsky.social!!
(View-only full text -> rdcu.be/eLlJs)
(View-only full text -> rdcu.be/eLlJs)
October 16, 2025 at 10:27 PM
Excited (😁) to share a commentary on @finngen.bsky.social & cancer research, co-written with Mervi Aavikko & @dalygene.bsky.social!!
(View-only full text -> rdcu.be/eLlJs)
(View-only full text -> rdcu.be/eLlJs)
So much great FinnGen science on display again today at #ASHG2025! Make sure to visit the posters listed here, and stop by at our booth (# 147) for some Finnish salmiakki!
October 16, 2025 at 3:06 PM
So much great FinnGen science on display again today at #ASHG2025! Make sure to visit the posters listed here, and stop by at our booth (# 147) for some Finnish salmiakki!
#ASHG2025 in Boston is off to a great start!
The FinnGen team is ready and waiting for you at Booth #147! Come say hi, explore insights from one of the world’s largest genomics initiatives and grab a FinnGen canvas bag (and other goodies)!
The FinnGen team is ready and waiting for you at Booth #147! Come say hi, explore insights from one of the world’s largest genomics initiatives and grab a FinnGen canvas bag (and other goodies)!
October 15, 2025 at 2:06 PM
#ASHG2025 in Boston is off to a great start!
The FinnGen team is ready and waiting for you at Booth #147! Come say hi, explore insights from one of the world’s largest genomics initiatives and grab a FinnGen canvas bag (and other goodies)!
The FinnGen team is ready and waiting for you at Booth #147! Come say hi, explore insights from one of the world’s largest genomics initiatives and grab a FinnGen canvas bag (and other goodies)!
Just in time for #ASHG2025, a new FinnGen public data release is live!
This release features the first clinical laboratory value association results. Analyses cover 383 lab measurements (OMOPIDs) with data from ≥1,000 participants each.
Access the results here: www.finngen.fi/en/access_re...
This release features the first clinical laboratory value association results. Analyses cover 383 lab measurements (OMOPIDs) with data from ≥1,000 participants each.
Access the results here: www.finngen.fi/en/access_re...
October 14, 2025 at 2:17 PM
Just in time for #ASHG2025, a new FinnGen public data release is live!
This release features the first clinical laboratory value association results. Analyses cover 383 lab measurements (OMOPIDs) with data from ≥1,000 participants each.
Access the results here: www.finngen.fi/en/access_re...
This release features the first clinical laboratory value association results. Analyses cover 383 lab measurements (OMOPIDs) with data from ≥1,000 participants each.
Access the results here: www.finngen.fi/en/access_re...