Jeremy Elman
@jaelman.bsky.social
Alzheimer's & aging researcher at UC San Diego
This world series should have come with a health warning.
November 2, 2025 at 4:04 AM
This world series should have come with a health warning.
Reposted by Jeremy Elman
HAPPENING NOW: A MASSIVE crowd of protesters flood the streets of San Diego for a “No Kings Day” rally showing their love for America and standing up against the corrupt fascist Trump administration. look how huge it is
October 18, 2025 at 6:34 PM
HAPPENING NOW: A MASSIVE crowd of protesters flood the streets of San Diego for a “No Kings Day” rally showing their love for America and standing up against the corrupt fascist Trump administration. look how huge it is
Check out our data! Please reach out if you're interested, we're happy to provide more info and we may have useful datasets (e.g., with extra cleaning or composite variables) to address specific questions. Raw and derived MRI data also available upon request for ~1/2 the cohort.
🚨NEW DATA RELEASE🚨
Data from VETSA waves 1-3 is now available for public download from NACDA! This includes cognitive, health, psychosocial and demographic info from our nationwide twin cohort. Future releases will include wave 4 data and derived MRI variables.
www.icpsr.umich.edu/web/ICPSR/st...
Data from VETSA waves 1-3 is now available for public download from NACDA! This includes cognitive, health, psychosocial and demographic info from our nationwide twin cohort. Future releases will include wave 4 data and derived MRI variables.
www.icpsr.umich.edu/web/ICPSR/st...
Vietnam Era Twin Study of Aging (VETSA), United States, 2002-2019
www.icpsr.umich.edu
September 26, 2025 at 3:28 PM
Check out our data! Please reach out if you're interested, we're happy to provide more info and we may have useful datasets (e.g., with extra cleaning or composite variables) to address specific questions. Raw and derived MRI data also available upon request for ~1/2 the cohort.
Reposted by Jeremy Elman
New paper out from the lab, demonstrating a robust non-linear relationship between age at menopause and dementia risk. Fantastic work by post-doc Dr. Ursula Saelzler. alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Age of menopause and dementia risk in 10,832 women from the Swedish Twin Registry
INTRODUCTION
An earlier age of menopause (AOM) is hypothesized to increase vulnerability to the neuropathological processes of dementia, which begin in midlife.
METHODS
We tested this hypothesis i.....
alz-journals.onlinelibrary.wiley.com
August 8, 2025 at 3:48 AM
New paper out from the lab, demonstrating a robust non-linear relationship between age at menopause and dementia risk. Fantastic work by post-doc Dr. Ursula Saelzler. alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Jeremy Elman
Excited to share my new study with the
VETSA team (vetsa.bsky.social) with jaelman.bsky.social and matthewpanizzon.bsky.social published in #JINS showing that moderate-to-severe chronic pain and opioid use are independently related to risk of mild cognitive impairment. tinyurl.com/y88k5z4j
VETSA team (vetsa.bsky.social) with jaelman.bsky.social and matthewpanizzon.bsky.social published in #JINS showing that moderate-to-severe chronic pain and opioid use are independently related to risk of mild cognitive impairment. tinyurl.com/y88k5z4j
July 22, 2025 at 11:08 PM
Excited to share my new study with the
VETSA team (vetsa.bsky.social) with jaelman.bsky.social and matthewpanizzon.bsky.social published in #JINS showing that moderate-to-severe chronic pain and opioid use are independently related to risk of mild cognitive impairment. tinyurl.com/y88k5z4j
VETSA team (vetsa.bsky.social) with jaelman.bsky.social and matthewpanizzon.bsky.social published in #JINS showing that moderate-to-severe chronic pain and opioid use are independently related to risk of mild cognitive impairment. tinyurl.com/y88k5z4j
Reposted by Jeremy Elman
Excited to share my new K01 work to understand chronic pain as an AD risk factor - a collaboration of the VETSA team (vetsa.bsky.social) with jaelman.bsky.social and matthewpanizzon.bsky.social and Rush Medical University using the ROSMAP data. academic.oup.com/braincomms/a...
Multisite chronic pain: association with cognitive decline and post-mortem Alzheimer’s biomarkers
Bell et al. report that multisite chronic pain in older adults is linked to faster cognitive decline and increased Alzheimer’s disease pathology, particula
academic.oup.com
July 22, 2025 at 11:11 PM
Excited to share my new K01 work to understand chronic pain as an AD risk factor - a collaboration of the VETSA team (vetsa.bsky.social) with jaelman.bsky.social and matthewpanizzon.bsky.social and Rush Medical University using the ROSMAP data. academic.oup.com/braincomms/a...
Reposted by Jeremy Elman
Study from Nathan Gillespie testing causal associations of plasma amyloid on total tau using #VETSA twin data.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Testing the causal impact of plasma amyloid on total Tau using a genetically informative sample of adult male twins
The amyloid cascade hypothesis predicts that amyloid-beta (Aβ) aggregation drives tau tangle accumulation. We tested competing causal and non-causal h…
www.sciencedirect.com
July 22, 2025 at 11:05 PM
Study from Nathan Gillespie testing causal associations of plasma amyloid on total tau using #VETSA twin data.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Jeremy Elman
Study by Alex Posis finding that TBI is associated with altered microstructure of certain WM tracts that may persist at least 4 decades after the injury.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Associations of history of traumatic brain injury with markers of brain health among older men in the Vietnam Era Twin Study of Aging
Traumatic brain injury (TBI) is associated with increased risk of dementia, but it is unclear how earlier life TBI is related to brain health in older…
www.sciencedirect.com
July 22, 2025 at 10:56 PM
Study by Alex Posis finding that TBI is associated with altered microstructure of certain WM tracts that may persist at least 4 decades after the injury.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Jeremy Elman
Happy to share a new published study link.springer.com/article/10.1...
on subjective memory concern, negative affect, and cortical microstructure using @vetsa.bsky.social dataset and supported by a K01 grant from the NIA!
on subjective memory concern, negative affect, and cortical microstructure using @vetsa.bsky.social dataset and supported by a K01 grant from the NIA!
link.springer.com
July 22, 2025 at 10:49 PM
Happy to share a new published study link.springer.com/article/10.1...
on subjective memory concern, negative affect, and cortical microstructure using @vetsa.bsky.social dataset and supported by a K01 grant from the NIA!
on subjective memory concern, negative affect, and cortical microstructure using @vetsa.bsky.social dataset and supported by a K01 grant from the NIA!
Reposted by Jeremy Elman
‼️NEW PREPRINT‼️
What if you could take a normal 3T T1w MRI and make it look like it was acquired from a 7T scanner?
That's exactly what we do using AI in our new preprint!
Link: arxiv.org/abs/2507.13782
#neuroskyence #neurosky #compneuro #AI #datascience #neurology #mrisky #neuroimaging
What if you could take a normal 3T T1w MRI and make it look like it was acquired from a 7T scanner?
That's exactly what we do using AI in our new preprint!
Link: arxiv.org/abs/2507.13782
#neuroskyence #neurosky #compneuro #AI #datascience #neurology #mrisky #neuroimaging
July 22, 2025 at 3:34 AM
‼️NEW PREPRINT‼️
What if you could take a normal 3T T1w MRI and make it look like it was acquired from a 7T scanner?
That's exactly what we do using AI in our new preprint!
Link: arxiv.org/abs/2507.13782
#neuroskyence #neurosky #compneuro #AI #datascience #neurology #mrisky #neuroimaging
What if you could take a normal 3T T1w MRI and make it look like it was acquired from a 7T scanner?
That's exactly what we do using AI in our new preprint!
Link: arxiv.org/abs/2507.13782
#neuroskyence #neurosky #compneuro #AI #datascience #neurology #mrisky #neuroimaging
Reposted by Jeremy Elman
Incredibly excited for this new work from our lab. We test the potential of AI-based neurodegenerative disease diagnostics using plasma proteomics data from n>17,000 people, led by the brilliant and indefatigable @anlijuncn.bsky.social Check it out!👇
Can AI reveal risk & co-pathology of multiple neurodegenerative diseases from a single blood sample? We explored AI-based diagnostic power on high rank plasma proteomics (N=17,170). www.medrxiv.org/content/10.1... #neuroskyence #neurosky #Alzheimer #compneuro #AI #datascience #neurology
Benchmarking the AI-based diagnostic potential of plasma proteomics for neurodegenerative disease in 17,170 people
Co-pathology is a common feature of neurodegenerative diseases that complicates diagnosis, treatment and clinical management. However, sensitive, specific and scalable biomarkers for in vivo pathologi...
www.medrxiv.org
July 17, 2025 at 5:51 AM
Incredibly excited for this new work from our lab. We test the potential of AI-based neurodegenerative disease diagnostics using plasma proteomics data from n>17,000 people, led by the brilliant and indefatigable @anlijuncn.bsky.social Check it out!👇
Trying to create directory tree for a new project or storage location? I did, but couldn't find an app that did exactly what I wanted, so I had GitHub Copilot + Claude create an app for me.
Link to the web app: jelman.github.io/TreeForge/
Link to the web app: jelman.github.io/TreeForge/
July 9, 2025 at 9:12 PM
Trying to create directory tree for a new project or storage location? I did, but couldn't find an app that did exactly what I wanted, so I had GitHub Copilot + Claude create an app for me.
Link to the web app: jelman.github.io/TreeForge/
Link to the web app: jelman.github.io/TreeForge/
The onslaught of 2025 can be so isolating. Today was a really great reminder that we're a community, and a large one at that.
June 14, 2025 at 11:26 PM
The onslaught of 2025 can be so isolating. Today was a really great reminder that we're a community, and a large one at that.
Reposted by Jeremy Elman
New work from our postdoc Seraphina Solders shows patterns of blood-brain barrier leakage in cognitively normal APOE4 carriers. BBB breakdown correlated with microstructural brain injury only in groups with high Alzheimer's disease risk (APOE4+, amyloid+, women) www.sciencedirect.com/science/arti...
Blood-brain barrier permeability varies by brain region and APOE4 status and correlates with brain microstructure among high-AD risk groups
Although strong evidence exists for blood–brain barrier (BBB) disruption in Alzheimer’s disease (AD), substantial uncertainty remains regarding its ro…
www.sciencedirect.com
June 2, 2025 at 1:27 AM
New work from our postdoc Seraphina Solders shows patterns of blood-brain barrier leakage in cognitively normal APOE4 carriers. BBB breakdown correlated with microstructural brain injury only in groups with high Alzheimer's disease risk (APOE4+, amyloid+, women) www.sciencedirect.com/science/arti...
This is a popular neighborhood restaurant on a corner with a lot of foot traffic. Rolling in like this on a Friday evening could only have been meant to send a message. It was guaranteed to be packed with folks from the neighborhood, including kids. No wonder they cover their faces.
San Diego erupts at ICE raiding a local restaurant and detaining ALL staff.
May 31, 2025 at 4:48 PM
This is a popular neighborhood restaurant on a corner with a lot of foot traffic. Rolling in like this on a Friday evening could only have been meant to send a message. It was guaranteed to be packed with folks from the neighborhood, including kids. No wonder they cover their faces.
Reposted by Jeremy Elman
Thank you @60minutes.bsky.social for giving the NIH freezes, termination, and proposed budget cuts the attention they deserve. ALL Americans, regardless of party, will feel this impact to their health far beyond one administration. www.cbsnews.com/video/nih-cu...
Federal cuts to National Institutes of Health could threaten medical progress
Former National Institutes of Health Director Dr. Francis Collins, who abruptly left his NIH research lab in February, fears aggressive downsizing could impact Americans’ health.
www.cbsnews.com
April 28, 2025 at 12:16 PM
Thank you @60minutes.bsky.social for giving the NIH freezes, termination, and proposed budget cuts the attention they deserve. ALL Americans, regardless of party, will feel this impact to their health far beyond one administration. www.cbsnews.com/video/nih-cu...
Reposted by Jeremy Elman
This Passover I’m thinking hard about the holiday’s history of resistance to tyrannical leaders, and the imperative for Jewish people to stand with all oppressed peoples of the world.
April 13, 2025 at 12:53 AM
This Passover I’m thinking hard about the holiday’s history of resistance to tyrannical leaders, and the imperative for Jewish people to stand with all oppressed peoples of the world.
Reposted by Jeremy Elman
NEW: The Trump administration is exploiting a loophole to keep funding frozen at the NIH - a move that some legal scholars say is illegal.
Federal Register notices are blocked, so no grant-review sessions can be scheduled.
All the gritty details here, and a short 🧵:
www.nature.com/articles/d41...
Federal Register notices are blocked, so no grant-review sessions can be scheduled.
All the gritty details here, and a short 🧵:
www.nature.com/articles/d41...
Revealed: NIH research grants still frozen despite lawsuits challenging Trump order
The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.
www.nature.com
February 20, 2025 at 8:27 PM
NEW: The Trump administration is exploiting a loophole to keep funding frozen at the NIH - a move that some legal scholars say is illegal.
Federal Register notices are blocked, so no grant-review sessions can be scheduled.
All the gritty details here, and a short 🧵:
www.nature.com/articles/d41...
Federal Register notices are blocked, so no grant-review sessions can be scheduled.
All the gritty details here, and a short 🧵:
www.nature.com/articles/d41...
Reposted by Jeremy Elman
This account is for sharing info with US scientists, both extramural and intramural to NIH, about attacks on science in the US.
Education is power, and we can help advocate for science and medicine together. 💪🧪
We are a team of NIH people. Please ask us questions you might have.
Education is power, and we can help advocate for science and medicine together. 💪🧪
We are a team of NIH people. Please ask us questions you might have.
January 30, 2025 at 1:18 AM
This account is for sharing info with US scientists, both extramural and intramural to NIH, about attacks on science in the US.
Education is power, and we can help advocate for science and medicine together. 💪🧪
We are a team of NIH people. Please ask us questions you might have.
Education is power, and we can help advocate for science and medicine together. 💪🧪
We are a team of NIH people. Please ask us questions you might have.
*Posted for McKenna Williams, not yet on BlueSky*
Our new paper on cognitive resilience against Alzheimer’s pathology is out now!
onlinelibrary.wiley.com/doi/full/10....
Our new paper on cognitive resilience against Alzheimer’s pathology is out now!
onlinelibrary.wiley.com/doi/full/10....
Neuroimaging Predictors of Cognitive Resilience against Alzheimer's Disease Pathology
Objective
Some individuals demonstrate greater cognitive resilience—the ability to maintain cognitive performance despite adverse brain-related changes—through as yet unknown mechanisms. We examined.....
onlinelibrary.wiley.com
February 12, 2025 at 11:35 PM
*Posted for McKenna Williams, not yet on BlueSky*
Our new paper on cognitive resilience against Alzheimer’s pathology is out now!
onlinelibrary.wiley.com/doi/full/10....
Our new paper on cognitive resilience against Alzheimer’s pathology is out now!
onlinelibrary.wiley.com/doi/full/10....
Reposted by Jeremy Elman
This has a twist. I promise it’s worth it
February 8, 2025 at 6:11 PM
This has a twist. I promise it’s worth it
Reposted by Jeremy Elman
🚨RED ALERT for 🧪:
The Trump NIH just gashed indirect costs. This is a direct attack on universities.
“Pursuant to this Supplemental Guidance, there will be a standard rate of 15% across all NIH grants for indirect costs.” 😮
Just a devastating Friday night news dump. #scicomm #academicaky
The Trump NIH just gashed indirect costs. This is a direct attack on universities.
“Pursuant to this Supplemental Guidance, there will be a standard rate of 15% across all NIH grants for indirect costs.” 😮
Just a devastating Friday night news dump. #scicomm #academicaky
February 7, 2025 at 11:40 PM
🚨RED ALERT for 🧪:
The Trump NIH just gashed indirect costs. This is a direct attack on universities.
“Pursuant to this Supplemental Guidance, there will be a standard rate of 15% across all NIH grants for indirect costs.” 😮
Just a devastating Friday night news dump. #scicomm #academicaky
The Trump NIH just gashed indirect costs. This is a direct attack on universities.
“Pursuant to this Supplemental Guidance, there will be a standard rate of 15% across all NIH grants for indirect costs.” 😮
Just a devastating Friday night news dump. #scicomm #academicaky
Reposted by Jeremy Elman
Just in case you thought that removing DEI criteria would mean that everyone is competing equally: NIH is removing grad students from underrepresented backgrounds from the applicant pool altogether. Their applications will not be considered. Other students, not from these backgrounds, will be.
February 6, 2025 at 7:59 PM
Just in case you thought that removing DEI criteria would mean that everyone is competing equally: NIH is removing grad students from underrepresented backgrounds from the applicant pool altogether. Their applications will not be considered. Other students, not from these backgrounds, will be.
Reposted by Jeremy Elman
🚨BREAKING. From a program officer at the National Science Foundation, a list of keywords that can cause a grant to be pulled. I will be sharing screenshots of these keywords along with a decision tree. Please share widely. This is a crisis for academic freedom & science.
February 4, 2025 at 1:26 AM
🚨BREAKING. From a program officer at the National Science Foundation, a list of keywords that can cause a grant to be pulled. I will be sharing screenshots of these keywords along with a decision tree. Please share widely. This is a crisis for academic freedom & science.
Reposted by Jeremy Elman
NEW: Trump says he's letting "lifesaving" foreign aid continue, but sources tell WIRED that DOGE is still blocking HIV/AIDS relief.
Musk brags he's "feeding USAID into the wood chipper."
A USAID worker tell us: “At a minimum, 300 babies that wouldn’t have had HIV now do."
By @knibbs.bsky.social
Musk brags he's "feeding USAID into the wood chipper."
A USAID worker tell us: “At a minimum, 300 babies that wouldn’t have had HIV now do."
By @knibbs.bsky.social
Elon Musk's DOGE Is Still Blocking HIV/AIDS Relief Exempted From Foreign Aid Cuts
The Trump Administration claims it is allowing "lifesaving" foreign aid to continue, but in reality, DOGE is preventing vital work on HIV and AIDS from saving lives.
www.wired.com
February 4, 2025 at 2:11 AM
NEW: Trump says he's letting "lifesaving" foreign aid continue, but sources tell WIRED that DOGE is still blocking HIV/AIDS relief.
Musk brags he's "feeding USAID into the wood chipper."
A USAID worker tell us: “At a minimum, 300 babies that wouldn’t have had HIV now do."
By @knibbs.bsky.social
Musk brags he's "feeding USAID into the wood chipper."
A USAID worker tell us: “At a minimum, 300 babies that wouldn’t have had HIV now do."
By @knibbs.bsky.social