Jon Grimm
@dyerfulchymist.bsky.social
Senior scientist and synthetic organic chemist working on fluorophore development in the Lavis lab at HHMI Janelia
Reposted by Jon Grimm
After those results, the Democratic response to GOP pressure to cave on the shutdown should simply be
a man in a suit and tie is sitting in a chair and making a funny face .
ALT: a man in a suit and tie is sitting in a chair and making a funny face .
media.tenor.com
November 5, 2025 at 1:00 PM
After those results, the Democratic response to GOP pressure to cave on the shutdown should simply be
Enjoy the day you voted for, MAGAts.
...too bad the rest of us have to live through it too.
...too bad the rest of us have to live through it too.
When the ACA enhanced premium tax credits expire later this year, thousands of Washington families will see their health insurance costs skyrocket.
A thread on premium increases: here's what happens to a self-insured middle-class couple's health premiums in King County.
A thread on premium increases: here's what happens to a self-insured middle-class couple's health premiums in King County.
October 30, 2025 at 3:00 PM
Enjoy the day you voted for, MAGAts.
...too bad the rest of us have to live through it too.
...too bad the rest of us have to live through it too.
It's official: we are great again.
You can now preview 2026 ACA insurance premiums on healthcare.gov.
A family of four in Maricopa County paid $514 a month for their ACA plan in 2025. Next year, that same plan will cost $2,435. That kind of increase will be devastating for thousands of Arizona families.
A family of four in Maricopa County paid $514 a month for their ACA plan in 2025. Next year, that same plan will cost $2,435. That kind of increase will be devastating for thousands of Arizona families.
October 30, 2025 at 2:58 PM
It's official: we are great again.
Reposted by Jon Grimm
Updating my LEGO White House
October 23, 2025 at 2:51 AM
Updating my LEGO White House
Are we GrEaT aGaIn yet?
Promises made, promises not given a shit about. It can only good happen!
www.newsweek.com/americans-li...
Promises made, promises not given a shit about. It can only good happen!
www.newsweek.com/americans-li...
Number of Americans living paycheck to paycheck soars
Rising expenses and competing financial priorities have left millions of Americans struggling to save up for a secure retirement.
www.newsweek.com
October 9, 2025 at 3:30 PM
Are we GrEaT aGaIn yet?
Promises made, promises not given a shit about. It can only good happen!
www.newsweek.com/americans-li...
Promises made, promises not given a shit about. It can only good happen!
www.newsweek.com/americans-li...
@edzitron.com has literally been saying this for years.
NVIDIA and OpenAi:
Concerns that their “increasingly complex and interconnected web of business transactions is artificially propping up the trillion-dollar AI boom.“
@bloomberg.com $NVDA 👀
www.bloomberg.com/news/feature...
Concerns that their “increasingly complex and interconnected web of business transactions is artificially propping up the trillion-dollar AI boom.“
@bloomberg.com $NVDA 👀
www.bloomberg.com/news/feature...
October 8, 2025 at 6:46 PM
@edzitron.com has literally been saying this for years.
Reposted by Jon Grimm
I feel like this photo of masked, armed men pepper spraying a pastor protecting his community is going to be a defining picture of this moment in America for a long, long time.
October 7, 2025 at 11:29 PM
I feel like this photo of masked, armed men pepper spraying a pastor protecting his community is going to be a defining picture of this moment in America for a long, long time.
Reposted by Jon Grimm
google wants to introduce errors into my spreadsheets and attribute them to me
October 7, 2025 at 5:59 PM
google wants to introduce errors into my spreadsheets and attribute them to me
Looking for a clear, concise explanation of how insidious and destructive LLMs and generative AI are, either for yourself or for friends who are unaware how truly terrible it is? This video from @kurzgesagt.org is an excellent summary of its existential threat. www.youtube.com/watch?v=_zfN...
AI Slop Is Killing Our Channel
YouTube video by Kurzgesagt – In a Nutshell
www.youtube.com
October 7, 2025 at 5:21 PM
Looking for a clear, concise explanation of how insidious and destructive LLMs and generative AI are, either for yourself or for friends who are unaware how truly terrible it is? This video from @kurzgesagt.org is an excellent summary of its existential threat. www.youtube.com/watch?v=_zfN...
Check it out, new version of the plagiarism machine dropping! And artists / copyright holders have to opt OUT! Definitely not a sign that this is a gigantic bubble and a house of cards built on shuffling fake billions around, no sir!
Generative AI is a scourge.
www.reuters.com/technology/o...
Generative AI is a scourge.
www.reuters.com/technology/o...
OpenAI's new Sora video generator to require copyright holders to opt out, WSJ reports
OpenAI is planning to release a new version of its Sora video generator that creates videos featuring copyrighted material, unless copyright holders opt out of having their work appear, the Wall Street Journal reported on Monday, citing people familiar with the matter.
www.reuters.com
October 6, 2025 at 11:53 AM
Check it out, new version of the plagiarism machine dropping! And artists / copyright holders have to opt OUT! Definitely not a sign that this is a gigantic bubble and a house of cards built on shuffling fake billions around, no sir!
Generative AI is a scourge.
www.reuters.com/technology/o...
Generative AI is a scourge.
www.reuters.com/technology/o...
Reposted by Jon Grimm
Also - it is shocking and appalling that OpenAI CFO Sarah Friar signed off on the revenue projections OpenAI leaked, because she is affirming that they project to make *more revenue than NVIDIA and TSMC* in the next four years. Utterly ridiculous.
September 12, 2025 at 12:21 AM
Also - it is shocking and appalling that OpenAI CFO Sarah Friar signed off on the revenue projections OpenAI leaked, because she is affirming that they project to make *more revenue than NVIDIA and TSMC* in the next four years. Utterly ridiculous.
Reposted by Jon Grimm
OpenAI will, starting in 2028, have to start paying $30bn a year to Oracle, $28bn to Microsoft for Azure, and also $2.9bn to CoreWeave for compute. That’s $60.9 billion *in compute costs alone*. This company is an absolute joke and should be treated as such.
www.theinformation.com/articles/ope...
www.theinformation.com/articles/ope...
July 22, 2025 at 6:08 AM
OpenAI will, starting in 2028, have to start paying $30bn a year to Oracle, $28bn to Microsoft for Azure, and also $2.9bn to CoreWeave for compute. That’s $60.9 billion *in compute costs alone*. This company is an absolute joke and should be treated as such.
www.theinformation.com/articles/ope...
www.theinformation.com/articles/ope...
Reposted by Jon Grimm
The truth here is so ever relevant, is so simple and profound. I think I might pop it into my next book. Sharing yet again:
July 30, 2025 at 3:26 PM
The truth here is so ever relevant, is so simple and profound. I think I might pop it into my next book. Sharing yet again:
Reposted by Jon Grimm
Reposted by Jon Grimm
Finally out in Nature Chem Bio:
SNAP-tag2 for faster and brighter protein labeling
www.nature.com/articles/s41...
Thank you Steffi and Veselin.
SNAP-tag2 for faster and brighter protein labeling
www.nature.com/articles/s41...
Thank you Steffi and Veselin.
SNAP-tag2 for faster and brighter protein labeling - Nature Chemical Biology
SNAP-tag is a widespread tool for labeling protein for bioimaging. Now, Kühn et al. report SNAP-tag2 with increased labeling kinetics and brightness, which translates into a better performance in live...
www.nature.com
July 3, 2025 at 7:45 PM
Finally out in Nature Chem Bio:
SNAP-tag2 for faster and brighter protein labeling
www.nature.com/articles/s41...
Thank you Steffi and Veselin.
SNAP-tag2 for faster and brighter protein labeling
www.nature.com/articles/s41...
Thank you Steffi and Veselin.
Reposted by Jon Grimm
Support your local wannabe hooker by donating to my congressional campaign:
secure.actblue.com/donate/abu-b...
secure.actblue.com/donate/abu-b...
July 2, 2025 at 2:02 AM
Support your local wannabe hooker by donating to my congressional campaign:
secure.actblue.com/donate/abu-b...
secure.actblue.com/donate/abu-b...
Reposted by Jon Grimm
“Independence day is canceled because of fear of secret police raids” is really a level of on the nose political symbolism you just can’t make up.
LA Times - Several communities in Los Angeles County have called off or postponed their previously scheduled Independence Day and July events, citing resident safety amid ongoing immigration enforcement raids.
Fear of immigration raids force the cancellation of several July festivities in Los Angeles
Here are some of the July festivities that have been canceled in Los Angeles out of fear over immigration raids.
www.latimes.com
June 28, 2025 at 7:51 PM
“Independence day is canceled because of fear of secret police raids” is really a level of on the nose political symbolism you just can’t make up.
Reposted by Jon Grimm
it is no exaggeration at all to say that these are people who would rather destroy the state's flagship public university than education a diverse cross-section of the commonwealth's students
I get to be the proud alum who explains to everybody in the group chat how the governor pushed people onto the board and those new members began working with DOJ to threaten the president so he would resign so they could do a coup and replace him with someone that would destroy the university
June 27, 2025 at 8:02 PM
it is no exaggeration at all to say that these are people who would rather destroy the state's flagship public university than education a diverse cross-section of the commonwealth's students
Reposted by Jon Grimm
the president does not actually have the power to fire a university president or a museum director, but if elites simply roll over under pressure, then effectively he does
June 27, 2025 at 5:04 PM
the president does not actually have the power to fire a university president or a museum director, but if elites simply roll over under pressure, then effectively he does
Reposted by Jon Grimm
HUGE NEWS!!!!
A new poll has me within single digits of leading in my race, ahead of FIVE other career politicians. This is incredible!
I was a "long shot" in March. Now we’re proving that grassroots campaigns can be viable and win — but I can’t do it without your help.
A new poll has me within single digits of leading in my race, ahead of FIVE other career politicians. This is incredible!
I was a "long shot" in March. Now we’re proving that grassroots campaigns can be viable and win — but I can’t do it without your help.
June 23, 2025 at 1:38 PM
HUGE NEWS!!!!
A new poll has me within single digits of leading in my race, ahead of FIVE other career politicians. This is incredible!
I was a "long shot" in March. Now we’re proving that grassroots campaigns can be viable and win — but I can’t do it without your help.
A new poll has me within single digits of leading in my race, ahead of FIVE other career politicians. This is incredible!
I was a "long shot" in March. Now we’re proving that grassroots campaigns can be viable and win — but I can’t do it without your help.
Reposted by Jon Grimm
🧵 A lot of people ask me the best way they can support my campaign and right now, that's donating.
If you're able, chipping in $5, $15, or $50 makes the biggest difference — and send our donation link to 3 friends while you're at it!
But let me tell you how your money will be used:
If you're able, chipping in $5, $15, or $50 makes the biggest difference — and send our donation link to 3 friends while you're at it!
But let me tell you how your money will be used:
HUGE NEWS!!!!
A new poll has me within single digits of leading in my race, ahead of FIVE other career politicians. This is incredible!
I was a "long shot" in March. Now we’re proving that grassroots campaigns can be viable and win — but I can’t do it without your help.
A new poll has me within single digits of leading in my race, ahead of FIVE other career politicians. This is incredible!
I was a "long shot" in March. Now we’re proving that grassroots campaigns can be viable and win — but I can’t do it without your help.
June 23, 2025 at 1:58 PM
🧵 A lot of people ask me the best way they can support my campaign and right now, that's donating.
If you're able, chipping in $5, $15, or $50 makes the biggest difference — and send our donation link to 3 friends while you're at it!
But let me tell you how your money will be used:
If you're able, chipping in $5, $15, or $50 makes the biggest difference — and send our donation link to 3 friends while you're at it!
But let me tell you how your money will be used:
Reposted by Jon Grimm
For those of you who might use ChatGPT or any kind of GenAI for your writing, give this a read and maybe reconsider
Diabolus Ex Machina
This Is Not An Essay
amandaguinzburg.substack.com
June 4, 2025 at 5:53 AM
For those of you who might use ChatGPT or any kind of GenAI for your writing, give this a read and maybe reconsider
Reposted by Jon Grimm
You don’t need a think tank to figure this out.
Every single person in the world wants to be safe and comfortably afford housing, groceries, and healthcare. It’s really that simple.
Every single person in the world wants to be safe and comfortably afford housing, groceries, and healthcare. It’s really that simple.
EXCLUSIVE: A top Democratic strategist has launched new policy research and messaging hub, called Searchlight, with a goal of pushing the party toward the most effective, broadly popular positions.
Dems are quietly forming a think tank to help them win again
Searchlight, a name inspired by the birthplace of Senate Majority Leader Harry Reid, comes at a precarious moment for a Democratic Party.
www.politico.com
June 4, 2025 at 1:37 PM
You don’t need a think tank to figure this out.
Every single person in the world wants to be safe and comfortably afford housing, groceries, and healthcare. It’s really that simple.
Every single person in the world wants to be safe and comfortably afford housing, groceries, and healthcare. It’s really that simple.
Reposted by Jon Grimm
Gen X could control the world if we (a) got rid of GPS, (b) required all cars to have manual transmissions, and (c) wrote in cursive.
June 4, 2025 at 12:59 PM
Gen X could control the world if we (a) got rid of GPS, (b) required all cars to have manual transmissions, and (c) wrote in cursive.