Elvira De Leonibus
@deleonibuslab.bsky.social
In love with my Kids and Sanfilippo kids, neuroscience, dopamine, memory
June 26, 2025 at 6:57 PM
🧠 Congrats Diletta Cavezza presenting at the:
@hippocampus spring meeting (lnkd.in/di4KNgYgin) in Verona!
"#Sex-dependent engagement of reuniens-hippocampal pathway during incidental encoding"
#Consiglio Nazionale delle Ricerche - IBBC
#Mnesys
Tigem
#Fondazione Telethon
Great meeting
@hippocampus spring meeting (lnkd.in/di4KNgYgin) in Verona!
"#Sex-dependent engagement of reuniens-hippocampal pathway during incidental encoding"
#Consiglio Nazionale delle Ricerche - IBBC
#Mnesys
Tigem
#Fondazione Telethon
Great meeting
May 19, 2025 at 7:42 PM
🧠 Congrats Diletta Cavezza presenting at the:
@hippocampus spring meeting (lnkd.in/di4KNgYgin) in Verona!
"#Sex-dependent engagement of reuniens-hippocampal pathway during incidental encoding"
#Consiglio Nazionale delle Ricerche - IBBC
#Mnesys
Tigem
#Fondazione Telethon
Great meeting
@hippocampus spring meeting (lnkd.in/di4KNgYgin) in Verona!
"#Sex-dependent engagement of reuniens-hippocampal pathway during incidental encoding"
#Consiglio Nazionale delle Ricerche - IBBC
#Mnesys
Tigem
#Fondazione Telethon
Great meeting
Great!
Targeted gene transfer into developmentally defined cell populations of the primate brain https://www.biorxiv.org/content/10.1101/2025.04.11.648413v1
April 18, 2025 at 6:25 PM
Great!
🧠💥 For #Dopamine (DA) & #Memory lovers!
📢 New paper!! we show that memory capacity (MC) in mice can be expanded from 6 to 8 objects using low doses of a D1 receptor agonist. Higher doses? Paradoxically, they reduce MC.
#Tigem
#Consiglio Nazionale delle Ricerche
lnkd.in/d9skfGeb
📢 New paper!! we show that memory capacity (MC) in mice can be expanded from 6 to 8 objects using low doses of a D1 receptor agonist. Higher doses? Paradoxically, they reduce MC.
#Tigem
#Consiglio Nazionale delle Ricerche
lnkd.in/d9skfGeb
April 3, 2025 at 9:35 AM
🧠💥 For #Dopamine (DA) & #Memory lovers!
📢 New paper!! we show that memory capacity (MC) in mice can be expanded from 6 to 8 objects using low doses of a D1 receptor agonist. Higher doses? Paradoxically, they reduce MC.
#Tigem
#Consiglio Nazionale delle Ricerche
lnkd.in/d9skfGeb
📢 New paper!! we show that memory capacity (MC) in mice can be expanded from 6 to 8 objects using low doses of a D1 receptor agonist. Higher doses? Paradoxically, they reduce MC.
#Tigem
#Consiglio Nazionale delle Ricerche
lnkd.in/d9skfGeb
Reposted by Elvira De Leonibus
Looking for an exciting fellowship in AI & Neuro, with competitive salary (~£100k)? We got a new position in the lab at Oxford, working with @somnirons.bsky.social and me! 🧪
Our project: encode.pillar.vc/projects/beh...
General info: encode.pillar.vc
#compneuro #neuroai #neuroscience #sciencejobs
Our project: encode.pillar.vc/projects/beh...
General info: encode.pillar.vc
#compneuro #neuroai #neuroscience #sciencejobs
ARIA Opportunity Space: Scalable Neural Interfaces
encode.pillar.vc
March 23, 2025 at 7:45 PM
Looking for an exciting fellowship in AI & Neuro, with competitive salary (~£100k)? We got a new position in the lab at Oxford, working with @somnirons.bsky.social and me! 🧪
Our project: encode.pillar.vc/projects/beh...
General info: encode.pillar.vc
#compneuro #neuroai #neuroscience #sciencejobs
Our project: encode.pillar.vc/projects/beh...
General info: encode.pillar.vc
#compneuro #neuroai #neuroscience #sciencejobs
It took so much time to get here, we cannot give up!
Super disappointing but it shouldn't stop us as reviewers from hammering grants and manuscripts that don't consider sex as a biological variable. We don't (...shouldn't) need an NIH mandate to do good science.
(But come on seriously this is so frustrating)
(But come on seriously this is so frustrating)
Great write up at @thetransmitter.bsky.social on the seeming erasure of SABV in the new era of NIH. Gotta say The Transmitter is killing it the last few weeks, first to report on the Federal Register block and now this. Leading the charge! 💪 www.thetransmitter.org/policy/exclu...
February 25, 2025 at 5:13 PM
It took so much time to get here, we cannot give up!
Reposted by Elvira De Leonibus
Young researchers mobilize to protest Trump administration’s science policies www.statnews.com/2025/02/13/r... via @statnews.com
@jpflores.bsky.social @samschuelstein.bsky.social @emmalovesscience.bsky.social @leslie-bern.bsky.social @standupforscience.bsky.social
@jpflores.bsky.social @samschuelstein.bsky.social @emmalovesscience.bsky.social @leslie-bern.bsky.social @standupforscience.bsky.social
Young researchers mobilize to protest Trump administration’s science policies
Stunned by attacks on the scientific research system, early career scientists plan a D.C. demonstration and a national ‘Stand Up for Science’ event.
www.statnews.com
February 13, 2025 at 12:32 PM
Young researchers mobilize to protest Trump administration’s science policies www.statnews.com/2025/02/13/r... via @statnews.com
@jpflores.bsky.social @samschuelstein.bsky.social @emmalovesscience.bsky.social @leslie-bern.bsky.social @standupforscience.bsky.social
@jpflores.bsky.social @samschuelstein.bsky.social @emmalovesscience.bsky.social @leslie-bern.bsky.social @standupforscience.bsky.social
📢 💥 We are ecstatic to announce that another one of our studies on Sanfilippo disease has been published in #MolecularPsychiatry.
#Sanfilippo is a rare genetic lysosomal storage disorder (#LSD) that leads to #neurodegeneration and #dementia.
www.nature.com/articles/s41...
#Sanfilippo is a rare genetic lysosomal storage disorder (#LSD) that leads to #neurodegeneration and #dementia.
www.nature.com/articles/s41...
D1 dopamine receptor antagonists as a new therapeutic strategy to treat autistic-like behaviours in lysosomal storage disorders - Molecular Psychiatry
Molecular Psychiatry - D1 dopamine receptor antagonists as a new therapeutic strategy to treat autistic-like behaviours in lysosomal storage disorders
www.nature.com
February 2, 2025 at 6:26 PM
📢 💥 We are ecstatic to announce that another one of our studies on Sanfilippo disease has been published in #MolecularPsychiatry.
#Sanfilippo is a rare genetic lysosomal storage disorder (#LSD) that leads to #neurodegeneration and #dementia.
www.nature.com/articles/s41...
#Sanfilippo is a rare genetic lysosomal storage disorder (#LSD) that leads to #neurodegeneration and #dementia.
www.nature.com/articles/s41...
Non c'è mai fine al peggio!
President Trump announced today that he would seek to remove the US from the #ParisAgreement. “Such a move is in clear defiance of scientific realities and shows an administration cruelly indifferent to the harsh climate change impacts that people in the US and around the world are experiencing.”
President Trump Ignores Science, Makes Disgraceful Decision to Withdraw US from Paris Agreement
President Trump announced today that he would seek to remove the United States from the Paris Agreement. Statement by Rachel Cleetus, policy director for the Climate and Energy Program at UCS.
www.ucsusa.org
January 21, 2025 at 9:29 PM
Non c'è mai fine al peggio!
Reposted by Elvira De Leonibus
Remembering Eleanor Maguire, ‘trailblazer’ of human memory
www.thetransmitter.org/memory/remem...
#neuroscience
www.thetransmitter.org/memory/remem...
#neuroscience
Remembering Eleanor Maguire, ‘trailblazer’ of human memory
Maguire, mastermind of the famous London taxi-driver study, broadened the field and championed the importance of spatial representations in memory.
www.thetransmitter.org
January 21, 2025 at 8:37 PM
Remembering Eleanor Maguire, ‘trailblazer’ of human memory
www.thetransmitter.org/memory/remem...
#neuroscience
www.thetransmitter.org/memory/remem...
#neuroscience
Thank Bita @bita137.bsky.social for this post. It gives us an idea of how much scientists need training on mentoring and evaluation, to understand our limitations and biases.
What is worst advice you have ever received from an academic?
January 5, 2025 at 10:26 AM
Thank Bita @bita137.bsky.social for this post. It gives us an idea of how much scientists need training on mentoring and evaluation, to understand our limitations and biases.
Reposted by Elvira De Leonibus
Striatal stimulation enhances cognitive control and evidence processing in rodents and humans
www.science.org/doi/10.1126/...
#neuroscience
www.science.org/doi/10.1126/...
#neuroscience
Striatal stimulation enhances cognitive control and evidence processing in rodents and humans
Developing an animal model of human brain stimulation therapy reveals that striatal DBS enhances the brain’s ability to process conflicting evidence.
www.science.org
January 2, 2025 at 12:42 PM
Striatal stimulation enhances cognitive control and evidence processing in rodents and humans
www.science.org/doi/10.1126/...
#neuroscience
www.science.org/doi/10.1126/...
#neuroscience
Reposted by Elvira De Leonibus
Exciting news from the lab! In collaboration with our #EU-Nanobrigth partners, we’ve developed and tested a new probe for vibrational fiber photometry, enabling minimally invasive Raman spectroscopy deep into the 🧠. www.nature.com/articles/s41... @naturemethods.bsky.social
Vibrational fiber photometry: label-free and reporter-free minimally invasive Raman spectroscopy deep in the mouse brain - Nature Methods
Vibrational fiber photometry enables Raman spectroscopy in the mouse brain with low impact, owing to the use of tapered fibers.
www.nature.com
December 31, 2024 at 10:49 AM
Exciting news from the lab! In collaboration with our #EU-Nanobrigth partners, we’ve developed and tested a new probe for vibrational fiber photometry, enabling minimally invasive Raman spectroscopy deep into the 🧠. www.nature.com/articles/s41... @naturemethods.bsky.social
Reposted by Elvira De Leonibus
Anno Domini 2024
👉Nel mondo sono attivi 56 conflitti
👉A #Gaza sono stati uccisi oltre 3.000 bambini
👉In Italia 4,5 milioni di persone rinunciano alle cure
👉A Milano 1 km di poveri sono in fila per un pasto
Poi è stato anche un "anno difficile" per #ChiaraFerragni
👉Nel mondo sono attivi 56 conflitti
👉A #Gaza sono stati uccisi oltre 3.000 bambini
👉In Italia 4,5 milioni di persone rinunciano alle cure
👉A Milano 1 km di poveri sono in fila per un pasto
Poi è stato anche un "anno difficile" per #ChiaraFerragni
December 28, 2024 at 8:53 PM
Anno Domini 2024
👉Nel mondo sono attivi 56 conflitti
👉A #Gaza sono stati uccisi oltre 3.000 bambini
👉In Italia 4,5 milioni di persone rinunciano alle cure
👉A Milano 1 km di poveri sono in fila per un pasto
Poi è stato anche un "anno difficile" per #ChiaraFerragni
👉Nel mondo sono attivi 56 conflitti
👉A #Gaza sono stati uccisi oltre 3.000 bambini
👉In Italia 4,5 milioni di persone rinunciano alle cure
👉A Milano 1 km di poveri sono in fila per un pasto
Poi è stato anche un "anno difficile" per #ChiaraFerragni
Reposted by Elvira De Leonibus
Oggi il Servizio Sanitario Nazionale compie 46 anni.
La sua “mamma” sarebbe molto indignata per l’ignobile tradimento dei princìpi fondanti da lei voluti
#SalviamoSSN
La sua “mamma” sarebbe molto indignata per l’ignobile tradimento dei princìpi fondanti da lei voluti
#SalviamoSSN
December 23, 2024 at 4:02 PM
Oggi il Servizio Sanitario Nazionale compie 46 anni.
La sua “mamma” sarebbe molto indignata per l’ignobile tradimento dei princìpi fondanti da lei voluti
#SalviamoSSN
La sua “mamma” sarebbe molto indignata per l’ignobile tradimento dei princìpi fondanti da lei voluti
#SalviamoSSN
Reposted by Elvira De Leonibus
Announcing the 2025 "Engram and Ensembles in Learning and Memory" meeting, at @tcddublin.bsky.social
Half of speakers will be selected from abstracts submitted by trainees. Registration is open below, with discounted rates available until January 31st.
event.fourwaves.com/engramsensem...
Half of speakers will be selected from abstracts submitted by trainees. Registration is open below, with discounted rates available until January 31st.
event.fourwaves.com/engramsensem...
December 19, 2024 at 8:41 AM
Announcing the 2025 "Engram and Ensembles in Learning and Memory" meeting, at @tcddublin.bsky.social
Half of speakers will be selected from abstracts submitted by trainees. Registration is open below, with discounted rates available until January 31st.
event.fourwaves.com/engramsensem...
Half of speakers will be selected from abstracts submitted by trainees. Registration is open below, with discounted rates available until January 31st.
event.fourwaves.com/engramsensem...
Reposted by Elvira De Leonibus
Last update of our databases for the year.
Download them here:
493 early-career funding opportunities: research.jhu.edu/rdt/funding-...
313 postdoc fellowships: research.jhu.edu/rdt/funding-...
189 PhD fellowships: research.jhu.edu/rdt/funding-...
Download them here:
493 early-career funding opportunities: research.jhu.edu/rdt/funding-...
313 postdoc fellowships: research.jhu.edu/rdt/funding-...
189 PhD fellowships: research.jhu.edu/rdt/funding-...
December 14, 2024 at 6:28 PM
Last update of our databases for the year.
Download them here:
493 early-career funding opportunities: research.jhu.edu/rdt/funding-...
313 postdoc fellowships: research.jhu.edu/rdt/funding-...
189 PhD fellowships: research.jhu.edu/rdt/funding-...
Download them here:
493 early-career funding opportunities: research.jhu.edu/rdt/funding-...
313 postdoc fellowships: research.jhu.edu/rdt/funding-...
189 PhD fellowships: research.jhu.edu/rdt/funding-...
Reposted by Elvira De Leonibus
Over 30 prominent scientists call for a ban on the creation of a "mirror cell"--a microbe made of molecules that are mirror images of their natural forms. It could cause a mind-boggling global disaster. Here's my story [gift link] 🧪https://nyti.ms/3OUCXp6
A ‘Second Tree of Life’ Could Wreak Havoc, Scientists Warn (Gift Article)
Research on so-called mirror cells, which defy fundamental properties of living organisms, should be prohibited as too dangerous, biologists said.
nyti.ms
December 12, 2024 at 8:04 PM
Over 30 prominent scientists call for a ban on the creation of a "mirror cell"--a microbe made of molecules that are mirror images of their natural forms. It could cause a mind-boggling global disaster. Here's my story [gift link] 🧪https://nyti.ms/3OUCXp6
Reposted by Elvira De Leonibus
www.nature.com/articles/s41...
Congrats to Juan and Hugo and the rest of the authors. Not sure if anyone is on bsky yet.
Congrats to Juan and Hugo and the rest of the authors. Not sure if anyone is on bsky yet.
Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors - Nature Neuroscience
Ventral striatal dopamine D3 and D1 receptors regulate motivation and reinforcement, respectively, through dissociable physiological actions.
www.nature.com
December 14, 2024 at 4:10 PM
www.nature.com/articles/s41...
Congrats to Juan and Hugo and the rest of the authors. Not sure if anyone is on bsky yet.
Congrats to Juan and Hugo and the rest of the authors. Not sure if anyone is on bsky yet.
December 12, 2024 at 4:05 PM
#nerusocientists There is little we can do, but we can distante our delves and publicly condemn deliberate acts of violence, while advocating for an immediate ceasefire.
Psychologists and neuroscientists are calling for international pressure towards immediate ceasefire in Israel, Palestine & Lebanon, respect for international humanitarian law, end of the occupation, and release of all hostages.
Read & join us by signing here: tinyurl.com/PsychLetter
Read & join us by signing here: tinyurl.com/PsychLetter
Open letter of psychologists and neuroscientists for peace in the Middle East
We, psychologists and neuroscientists from around the world, call the international community to urgently put pressure towards an immediate ceasefire in Israel, Palestine and Lebanon, to demand that t...
tinyurl.com
November 27, 2024 at 11:52 AM
#nerusocientists There is little we can do, but we can distante our delves and publicly condemn deliberate acts of violence, while advocating for an immediate ceasefire.
Reposted by Elvira De Leonibus
Nature Neuroscience
Inhibitory plasticity supports replay generalization in the hippocampus
www.nature.com/articles/s41...
Inhibitory plasticity supports replay generalization in the hippocampus
www.nature.com/articles/s41...
Inhibitory plasticity supports replay generalization in the hippocampus - Nature Neuroscience
The study of neural plasticity has focused on excitatory neural connections, but inhibitory connections can also change. Learning at inhibitory synapses may support high-level cognitive phenomena, suc...
www.nature.com
November 25, 2024 at 6:46 AM
Nature Neuroscience
Inhibitory plasticity supports replay generalization in the hippocampus
www.nature.com/articles/s41...
Inhibitory plasticity supports replay generalization in the hippocampus
www.nature.com/articles/s41...
I quote and add "or with fancy approaches that do not add much, like replacing Pharmacology with chemogenetics"
I am old so I can say this: innovation in neuroscience research can be accelerated if we did not waste so much resources repeating what we already know from NHP and rat research in Cre mouse lines
November 25, 2024 at 6:24 PM
I quote and add "or with fancy approaches that do not add much, like replacing Pharmacology with chemogenetics"