Juan Carlos De la Concepcion
@delaconcepcionjc.bsky.social
Plants, Pathogens and Procrastination
Emmy Noether Fellow at ZMBP
Emmy Noether Fellow at ZMBP
Pinned
Please share!
My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th!
uni-tuebingen.de/universitaet...
My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th!
uni-tuebingen.de/universitaet...
Reposted by Juan Carlos De la Concepcion
Check out this cool #cryo-EM study spearheaded by our neighbor @tafurlab.bsky.social and his colleagues! A must-read for anyone interested in the molecular mechanisms governing (m)TORC1 regulation. Congrats to all involved! 🎉
It took a while but it’s finally published!
The GAP activity of SEAC (GATOR) is a metabolic switch that allows cells to quickly respond to changes in amino acid levels, both for inhibition and reactivation.
The GAP activity of SEAC (GATOR) is a metabolic switch that allows cells to quickly respond to changes in amino acid levels, both for inhibition and reactivation.
New online: Structure and function of the yeast amino acid-sensing SEAC–EGOC supercomplex
February 13, 2026 at 4:56 PM
Check out this cool #cryo-EM study spearheaded by our neighbor @tafurlab.bsky.social and his colleagues! A must-read for anyone interested in the molecular mechanisms governing (m)TORC1 regulation. Congrats to all involved! 🎉
Reposted by Juan Carlos De la Concepcion
In @science.org this week, thermospermine affects ribosome methylation, which in turn regulates translation of xylem development proteins www.science.org/doi/10.1126/...
#plantscience
#plantscience
Recruitment of bifunctional regulator thermospermine to methylated ribosomes directs xylem fate
Polyamines are often associated with ribosomes and are thought to stabilize their integrity. In Arabidopsis, the polyamine thermospermine (tSpm) affects xylem cell fate. tSpm induces translation of SU...
www.science.org
February 13, 2026 at 9:43 AM
In @science.org this week, thermospermine affects ribosome methylation, which in turn regulates translation of xylem development proteins www.science.org/doi/10.1126/...
#plantscience
#plantscience
Reposted by Juan Carlos De la Concepcion
Registration is now open! The 4th edition of the Mendel Early Career Symposium will take place on 21-22 May at the GMI, part of the @viennabiocenter.bsky.social. This two-day event brings together researchers across career stages to discuss the latest research in all areas of plant science.
January 27, 2026 at 11:20 AM
Registration is now open! The 4th edition of the Mendel Early Career Symposium will take place on 21-22 May at the GMI, part of the @viennabiocenter.bsky.social. This two-day event brings together researchers across career stages to discuss the latest research in all areas of plant science.
Reposted by Juan Carlos De la Concepcion
We’re hiring!
Postdoctoral Researcher / Research Assistant @KamounLab
“Biology and Applications of Plant Immune Receptors” www.tsl.ac.uk/working-at-t...
Postdoctoral Researcher / Research Assistant @KamounLab
“Biology and Applications of Plant Immune Receptors” www.tsl.ac.uk/working-at-t...
February 13, 2026 at 2:18 PM
We’re hiring!
Postdoctoral Researcher / Research Assistant @KamounLab
“Biology and Applications of Plant Immune Receptors” www.tsl.ac.uk/working-at-t...
Postdoctoral Researcher / Research Assistant @KamounLab
“Biology and Applications of Plant Immune Receptors” www.tsl.ac.uk/working-at-t...
Reposted by Juan Carlos De la Concepcion
It was believed in medieval times that hedgehogs had spikes so they could roll over fruit to carry home to their children, which is not true but is a really cute idea
February 13, 2026 at 11:26 AM
It was believed in medieval times that hedgehogs had spikes so they could roll over fruit to carry home to their children, which is not true but is a really cute idea
Reposted by Juan Carlos De la Concepcion
How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller?
Excited to share our latest work in @science.org on a new small polymerase.
1/n
Excited to share our latest work in @science.org on a new small polymerase.
1/n
A small polymerase ribozyme that can synthesize itself and its complementary strand
The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...
www.science.org
February 13, 2026 at 11:42 AM
How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller?
Excited to share our latest work in @science.org on a new small polymerase.
1/n
Excited to share our latest work in @science.org on a new small polymerase.
1/n
Reposted by Juan Carlos De la Concepcion
Vorholt Lab re-created endosymbiosis in the lab: injected bacteria into a fungus and evolved a heritable partnership.
Evolution, fast-forwarded.
doi.org/10.1038/s415...
Evolution, fast-forwarded.
doi.org/10.1038/s415...
Inducing novel endosymbioses by implanting bacteria in fungi - Nature
A study presents an approach to establish and track a new endosymbiotic partnership by implanting bacteria in a non-host fungus and shows that stable inheritance of the implanted bacteria is possible ...
doi.org
February 13, 2026 at 12:32 PM
Vorholt Lab re-created endosymbiosis in the lab: injected bacteria into a fungus and evolved a heritable partnership.
Evolution, fast-forwarded.
doi.org/10.1038/s415...
Evolution, fast-forwarded.
doi.org/10.1038/s415...
Reposted by Juan Carlos De la Concepcion
By 2028, all 4-character PDB IDs will be exhausted.
After that, all new entries will receive extended IDs: 12 characters total, formatted as pdb_ + 8 alphanumeric characters (pdb_1000axyz)
Test it from PDB Beta Archive
Read more: www.wwpdb.org/news/news?ye...
After that, all new entries will receive extended IDs: 12 characters total, formatted as pdb_ + 8 alphanumeric characters (pdb_1000axyz)
Test it from PDB Beta Archive
Read more: www.wwpdb.org/news/news?ye...
February 12, 2026 at 11:32 AM
By 2028, all 4-character PDB IDs will be exhausted.
After that, all new entries will receive extended IDs: 12 characters total, formatted as pdb_ + 8 alphanumeric characters (pdb_1000axyz)
Test it from PDB Beta Archive
Read more: www.wwpdb.org/news/news?ye...
After that, all new entries will receive extended IDs: 12 characters total, formatted as pdb_ + 8 alphanumeric characters (pdb_1000axyz)
Test it from PDB Beta Archive
Read more: www.wwpdb.org/news/news?ye...
Reposted by Juan Carlos De la Concepcion
Big news from our lab: we can now stably edit the genome of a parasitic plant! Transgene-free, genome-edited P. japonicum in one generation! This will transform how we study #parasiticplants and other hard-to-transform plants.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
February 12, 2026 at 9:24 AM
Big news from our lab: we can now stably edit the genome of a parasitic plant! Transgene-free, genome-edited P. japonicum in one generation! This will transform how we study #parasiticplants and other hard-to-transform plants.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Juan Carlos De la Concepcion
🚀 We’re hiring! The Structural Biology Platform is seeking a Project Leader to advance cryo-electron tomography and expand capabilities at the FMI. Join a vibrant research community at the interface of structural biology, cell biology & disease mechanisms. Apply at: www.fmi.ch/education-ca...
February 12, 2026 at 6:47 AM
🚀 We’re hiring! The Structural Biology Platform is seeking a Project Leader to advance cryo-electron tomography and expand capabilities at the FMI. Join a vibrant research community at the interface of structural biology, cell biology & disease mechanisms. Apply at: www.fmi.ch/education-ca...
Reposted by Juan Carlos De la Concepcion
And a new paper from the lab. A follow up to a previous study in which we elucidate the mechanism of the nuclear transport. Read the full story: www.nature.com/articles/s41...
February 11, 2026 at 5:12 PM
And a new paper from the lab. A follow up to a previous study in which we elucidate the mechanism of the nuclear transport. Read the full story: www.nature.com/articles/s41...
Reposted by Juan Carlos De la Concepcion
To regulate gene activity, proteasomes - waste disposal machines of cells - must enter the nucleus. IMP Researchers now show how the adaptor protein AKIRIN2 helps ferry this massive complex through the nuclear pore: https://www.nature.com/articles/s41467-026-69162-0
February 11, 2026 at 10:20 AM
To regulate gene activity, proteasomes - waste disposal machines of cells - must enter the nucleus. IMP Researchers now show how the adaptor protein AKIRIN2 helps ferry this massive complex through the nuclear pore: https://www.nature.com/articles/s41467-026-69162-0
Reposted by Juan Carlos De la Concepcion
CPK28 was already present in the first land plant, and presents a paradox: the Marchantia version can perfectly replace the Arabidopsis version for immunity, but does not seem to participate to immunity in Marchantia ...
A lot more molecular data here =>
www.biorxiv.org/content/10.1...
A lot more molecular data here =>
www.biorxiv.org/content/10.1...
www.biorxiv.org
February 10, 2026 at 9:25 PM
CPK28 was already present in the first land plant, and presents a paradox: the Marchantia version can perfectly replace the Arabidopsis version for immunity, but does not seem to participate to immunity in Marchantia ...
A lot more molecular data here =>
www.biorxiv.org/content/10.1...
A lot more molecular data here =>
www.biorxiv.org/content/10.1...
Reposted by Juan Carlos De la Concepcion
Students need to remember that Inigo Montoya method for emails and greetings:
"Hello, my name is Inigo Montoya. You killed my father. Prepare to die.”
Polite Greeting
Name
Relevant Personal Link
Manage Expectations
Keep it BRIEF.
"Hello, my name is Inigo Montoya. You killed my father. Prepare to die.”
Polite Greeting
Name
Relevant Personal Link
Manage Expectations
Keep it BRIEF.
am i the only 1 who wishes ppl would remind me that we've interacted before if it's plausible i've forgotten? I've had like 3-4 emails that seems like 'cold emails' ab research opportunities but then it turns out we've exchanged emails in the past & it's awkward to not have realized this? just me?
February 10, 2026 at 4:44 PM
Students need to remember that Inigo Montoya method for emails and greetings:
"Hello, my name is Inigo Montoya. You killed my father. Prepare to die.”
Polite Greeting
Name
Relevant Personal Link
Manage Expectations
Keep it BRIEF.
"Hello, my name is Inigo Montoya. You killed my father. Prepare to die.”
Polite Greeting
Name
Relevant Personal Link
Manage Expectations
Keep it BRIEF.
Reposted by Juan Carlos De la Concepcion
If Bad Bunny can cover the history of Puerto Rico, colonialism, transatlantic slavery, hemispheric consciousness, as well as contemporary life and politics in under 14 minutes, you can do your 15- or 20-minute conference presentation with time to spare.
February 9, 2026 at 11:56 PM
If Bad Bunny can cover the history of Puerto Rico, colonialism, transatlantic slavery, hemispheric consciousness, as well as contemporary life and politics in under 14 minutes, you can do your 15- or 20-minute conference presentation with time to spare.
Reposted by Juan Carlos De la Concepcion
Ulrich’s research will help advance our understanding of RNA biology & gene regulation, as well as how these mechanisms might be altered during viral infections & other diseases.
@hohmannulrich.bsky.social comes from the @impvienna.bsky.social / @imbavienna.bsky.social
www.imb.de/about-imb/ne...
@hohmannulrich.bsky.social comes from the @impvienna.bsky.social / @imbavienna.bsky.social
www.imb.de/about-imb/ne...
February 9, 2026 at 11:14 AM
Ulrich’s research will help advance our understanding of RNA biology & gene regulation, as well as how these mechanisms might be altered during viral infections & other diseases.
@hohmannulrich.bsky.social comes from the @impvienna.bsky.social / @imbavienna.bsky.social
www.imb.de/about-imb/ne...
@hohmannulrich.bsky.social comes from the @impvienna.bsky.social / @imbavienna.bsky.social
www.imb.de/about-imb/ne...
Reposted by Juan Carlos De la Concepcion
Long in the making, but happy to present the Chlamydomonas chlororibosome!
Cryo-ET🔬reveals a large new domain on the small subunit, built from multiple extensions in conserved ribosomal proteins.
bioRxiv 📖: shorturl.at/q44tG
This suggests greater chlororibosome diversity than expected!
1/n 🧵
Cryo-ET🔬reveals a large new domain on the small subunit, built from multiple extensions in conserved ribosomal proteins.
bioRxiv 📖: shorturl.at/q44tG
This suggests greater chlororibosome diversity than expected!
1/n 🧵
February 10, 2026 at 8:35 AM
Long in the making, but happy to present the Chlamydomonas chlororibosome!
Cryo-ET🔬reveals a large new domain on the small subunit, built from multiple extensions in conserved ribosomal proteins.
bioRxiv 📖: shorturl.at/q44tG
This suggests greater chlororibosome diversity than expected!
1/n 🧵
Cryo-ET🔬reveals a large new domain on the small subunit, built from multiple extensions in conserved ribosomal proteins.
bioRxiv 📖: shorturl.at/q44tG
This suggests greater chlororibosome diversity than expected!
1/n 🧵
Reposted by Juan Carlos De la Concepcion
@lorenzoorts.bsky.social previously worked as a postdoctoral fellow at @impvienna.bsky.social in Austria. She will establish a new lab at IMB to investigate how mRNA translation is activated in the early embryo. Welcome to IMB Laura! 💐
Read more here: www.imb.de/about-imb/ne...
Read more here: www.imb.de/about-imb/ne...
February 6, 2026 at 2:27 PM
@lorenzoorts.bsky.social previously worked as a postdoctoral fellow at @impvienna.bsky.social in Austria. She will establish a new lab at IMB to investigate how mRNA translation is activated in the early embryo. Welcome to IMB Laura! 💐
Read more here: www.imb.de/about-imb/ne...
Read more here: www.imb.de/about-imb/ne...
Reposted by Juan Carlos De la Concepcion
The physicist Lise Meitner, one of the few women in the room, felt much the same way. I first met Bohr in 1920 when he gave a lecture to the Physical Society in Berlin, she recalls.
February 8, 2026 at 11:29 AM
The physicist Lise Meitner, one of the few women in the room, felt much the same way. I first met Bohr in 1920 when he gave a lecture to the Physical Society in Berlin, she recalls.
Reposted by Juan Carlos De la Concepcion
Plants use cell-surface and intracellular receptors that collaborate to detect pathogens🦠. We discovered that a key #ubiquitin recognition event recruits both receptor types into an unexpected dual receptor complex that boost the translation of defence proteins and establishes robust #PlantImmunity👇🏾
February 9, 2026 at 9:57 AM
Plants use cell-surface and intracellular receptors that collaborate to detect pathogens🦠. We discovered that a key #ubiquitin recognition event recruits both receptor types into an unexpected dual receptor complex that boost the translation of defence proteins and establishes robust #PlantImmunity👇🏾
Reposted by Juan Carlos De la Concepcion
the bushes were people 😂
February 9, 2026 at 2:26 AM
the bushes were people 😂
Reposted by Juan Carlos De la Concepcion
That was a real wedding during Bad Bunny’s Super Bowl Halftime Show. His reps confirmed the happy couple are irl in love. And yet, conservatives still said the show was an affront to American values.
That Was a Real Wedding During Bad Bunny’s Halftime Show
That was a real wedding during Bad Bunny’s Super Bowl Halftime Show. His reps confirmed the happy couple are irl in love. And yet, conservatives still said the show was an affront to American values.
www.vulture.com
February 9, 2026 at 2:54 AM
That was a real wedding during Bad Bunny’s Super Bowl Halftime Show. His reps confirmed the happy couple are irl in love. And yet, conservatives still said the show was an affront to American values.
Reposted by Juan Carlos De la Concepcion
First shot: sugarcane
The backbone of Puerto Rico's agricultural economy since colonial times
Still used to make rum of course!
The backbone of Puerto Rico's agricultural economy since colonial times
Still used to make rum of course!
February 9, 2026 at 2:33 AM
First shot: sugarcane
The backbone of Puerto Rico's agricultural economy since colonial times
Still used to make rum of course!
The backbone of Puerto Rico's agricultural economy since colonial times
Still used to make rum of course!
Reposted by Juan Carlos De la Concepcion
A ubiquitin binding protein mediates the crosstalk between PTI and ETI! Check out our new preprint below 👇
Ubiquitin recognition integrates plant immune signaling by cell-surface and intracellular receptors https://www.biorxiv.org/content/10.64898/2026.02.06.703835v1
February 7, 2026 at 3:38 PM
A ubiquitin binding protein mediates the crosstalk between PTI and ETI! Check out our new preprint below 👇