Carsten Schulte
@carstenschulte4.bsky.social
Interdisciplinary cell biologist fascinated by (extra)cellular mechanobiology in (patho)physiology. Lecturer, Department of Biomedical Engineering @University of Strathclyde & CeMi. Tweets about science & other stuff in which I engage. Views are my own.
Jane Goodall, one of my inspirations to study biology. What a big loss for humanity! RIP
October 3, 2025 at 3:24 PM
Jane Goodall, one of my inspirations to study biology. What a big loss for humanity! RIP
Glasgow representation is strong @cellmech2025.bsky.social with @unistrathclyde.bsky.social & @uofglasgow.bsky.social @theglasgowcemi.bsky.social cell mechanobiologists united 😊!
October 1, 2025 at 1:56 PM
Glasgow representation is strong @cellmech2025.bsky.social with @unistrathclyde.bsky.social & @uofglasgow.bsky.social @theglasgowcemi.bsky.social cell mechanobiologists united 😊!
Reposted by Carsten Schulte
🧵A thread of threads of our invited speakers 👇
May 15, 2025 at 9:04 AM
🧵A thread of threads of our invited speakers 👇
On my way to CellMech25 in Leuven! I'm really looking forward to catching up with the Mechanobiology community! First time as Lecturer @unistrathclyde.bsky.social&PI @theglasgowcemi.bsky.social with parts of my group (Extra) Cellular Mechanobiology in Health and Disease @dylanjfowler.bsky.social 🤩!
September 29, 2025 at 8:18 AM
On my way to CellMech25 in Leuven! I'm really looking forward to catching up with the Mechanobiology community! First time as Lecturer @unistrathclyde.bsky.social&PI @theglasgowcemi.bsky.social with parts of my group (Extra) Cellular Mechanobiology in Health and Disease @dylanjfowler.bsky.social 🤩!
Congratulations Carmelo and team, brilliant work showing that mechanostimuli (through sound waves) can provoke nuclear chromatin responses in mesenchymal stem cells which directs the cells towards osteogenic lineage🤩!
Paper accepted!!!!
Congratultions to @lizebonaaugust.bsky.social Blanca del Rosal and Leslie Yeo it was a pleasure to work together on this amazing project! 🎊🎊🎊🎊
Congratultions to @lizebonaaugust.bsky.social Blanca del Rosal and Leslie Yeo it was a pleasure to work together on this amazing project! 🎊🎊🎊🎊
September 23, 2025 at 10:32 PM
Congratulations Carmelo and team, brilliant work showing that mechanostimuli (through sound waves) can provoke nuclear chromatin responses in mesenchymal stem cells which directs the cells towards osteogenic lineage🤩!
The core team of the Tenovus Scotland-funded Small Pilot Grant project "Leveraging mechanobiology for the optimisation of in vitro muscle-related disease models" is on the case😊, with a strong 4th&5th year students-driven component! @unistrathclyde.bsky.social @theglasgowcemi.bsky.social
September 22, 2025 at 10:29 PM
The core team of the Tenovus Scotland-funded Small Pilot Grant project "Leveraging mechanobiology for the optimisation of in vitro muscle-related disease models" is on the case😊, with a strong 4th&5th year students-driven component! @unistrathclyde.bsky.social @theglasgowcemi.bsky.social
Reposted by Carsten Schulte
Strathclyde named Scottish University of the Year and Runner-Up UK University of the Year by The Times and Sunday Times www.strath.ac.uk/whystrathcly...
September 19, 2025 at 8:51 AM
Strathclyde named Scottish University of the Year and Runner-Up UK University of the Year by The Times and Sunday Times www.strath.ac.uk/whystrathcly...
Very interesting story on the nuclear mechanoresponse to sono-stimulation!
EpiSci - 🧬 - 🧪 - 👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽
We just submitted an updated version of the previous preprint.
Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells
www.biorxiv.org/content/10.1...
We just submitted an updated version of the previous preprint.
Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells
www.biorxiv.org/content/10.1...
Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells
Cells effectively balance and integrate numerous pathways to adapt to external signals in an attempt to regain homeostasis, although the complex nuclear mechanotransduction mechanism through which thi...
www.biorxiv.org
September 11, 2025 at 12:44 PM
Very interesting story on the nuclear mechanoresponse to sono-stimulation!
Reposted by Carsten Schulte
EpiSci - 🧬 - 🧪 - 👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽
We just submitted an updated version of the previous preprint.
Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells
www.biorxiv.org/content/10.1...
We just submitted an updated version of the previous preprint.
Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells
www.biorxiv.org/content/10.1...
Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells
Cells effectively balance and integrate numerous pathways to adapt to external signals in an attempt to regain homeostasis, although the complex nuclear mechanotransduction mechanism through which thi...
www.biorxiv.org
September 11, 2025 at 9:43 AM
EpiSci - 🧬 - 🧪 - 👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽
We just submitted an updated version of the previous preprint.
Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells
www.biorxiv.org/content/10.1...
We just submitted an updated version of the previous preprint.
Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells
www.biorxiv.org/content/10.1...
We are very happy 😄 that our Rheinland-Pfalz & Scotland exchange project started, jointly awarded by @sulsa.bsky.social and JGU Scotland Hub, sponsored by the governments of 🏴 & Rheinland-Pfalz. 1/2
@unistrathclyde.bsky.social @theglasgowcemi.bsky.social @imbmainz.bsky.social @unimainz.bsky.social
@unistrathclyde.bsky.social @theglasgowcemi.bsky.social @imbmainz.bsky.social @unimainz.bsky.social
September 10, 2025 at 8:17 PM
We are very happy 😄 that our Rheinland-Pfalz & Scotland exchange project started, jointly awarded by @sulsa.bsky.social and JGU Scotland Hub, sponsored by the governments of 🏴 & Rheinland-Pfalz. 1/2
@unistrathclyde.bsky.social @theglasgowcemi.bsky.social @imbmainz.bsky.social @unimainz.bsky.social
@unistrathclyde.bsky.social @theglasgowcemi.bsky.social @imbmainz.bsky.social @unimainz.bsky.social
BioMedEng25 is over! I really enjoyed my talk&the opportunity present my research. I also talked about unpublished work from a collaboration with @carmeloferrai.bsky.social that is getting closer&closer to being deposited on @biorxivpreprint.bsky.social. Stay tuned 😀!
@biomedeng25.bsky.social
@biomedeng25.bsky.social
September 5, 2025 at 4:42 PM
BioMedEng25 is over! I really enjoyed my talk&the opportunity present my research. I also talked about unpublished work from a collaboration with @carmeloferrai.bsky.social that is getting closer&closer to being deposited on @biorxivpreprint.bsky.social. Stay tuned 😀!
@biomedeng25.bsky.social
@biomedeng25.bsky.social
Reposted by Carsten Schulte
This is an airyscan confocal movie of mitochondria (white) moving around in a mouse astrocyte. Actin filaments are in orange and microtubules are in blue.
August 18, 2025 at 1:39 AM
This is an airyscan confocal movie of mitochondria (white) moving around in a mouse astrocyte. Actin filaments are in orange and microtubules are in blue.
Reposted by Carsten Schulte
Our study on the mechanosensitive behavior of cell adhesion, showing the existence of a force-transmission mechanism that behaves very differently from the well-known 'load-and-fail' mechanism, was published in Nature Physics:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 18, 2025 at 9:46 AM
Our study on the mechanosensitive behavior of cell adhesion, showing the existence of a force-transmission mechanism that behaves very differently from the well-known 'load-and-fail' mechanism, was published in Nature Physics:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A little more than a year that @carmeloferrai.bsky.social and I published our review "Mechanotransduction in stem cells"🤯! I'm happy that it was received well 😃! Stay tuned, more to come in this direction in a not too far future😎.
EpiSci - Hi there! Our review “Mechanotransduction in stem cells” is finally published. With @carstenschulte4.bsky.social we provided a comprehensive picture, that aims to cover the whole mechanotransductive pathway from the cell microenvironment to the nucleus. 1/3 pubmed.ncbi.nlm.nih.gov/38729084/
June 27, 2025 at 8:37 PM
A little more than a year that @carmeloferrai.bsky.social and I published our review "Mechanotransduction in stem cells"🤯! I'm happy that it was received well 😃! Stay tuned, more to come in this direction in a not too far future😎.
Reposted by Carsten Schulte
A paper that I published as a co-first author in 2014 (with G.M. Ferraris and V. Buttiglione, supervised by N. Sidenius, not on bluesky) reached 100 citations.
Science social media weren't that big yet back then, so I seize this occasion to make a 🧵 about it now:
👉 www.embopress.org/doi/full/10....
Science social media weren't that big yet back then, so I seize this occasion to make a 🧵 about it now:
👉 www.embopress.org/doi/full/10....
The interaction between uPAR and vitronectin triggers ligand‐independent adhesion signalling by integrins | The EMBO Journal
image image Cell adhesion mediated by uPAR and other adhesion receptors triggers non‐canonical integrin activation independent
of integrin–ligand interactions. The cross‐talk between adhesion recepto...
www.embopress.org
May 6, 2025 at 2:27 PM
A paper that I published as a co-first author in 2014 (with G.M. Ferraris and V. Buttiglione, supervised by N. Sidenius, not on bluesky) reached 100 citations.
Science social media weren't that big yet back then, so I seize this occasion to make a 🧵 about it now:
👉 www.embopress.org/doi/full/10....
Science social media weren't that big yet back then, so I seize this occasion to make a 🧵 about it now:
👉 www.embopress.org/doi/full/10....
Reposted by Carsten Schulte
Getting something done at work
June 20, 2025 at 7:08 AM
Getting something done at work
Reposted by Carsten Schulte
So ist es, liebes BMFTR: Die Chancen sind für jede Generation ✨vergleichbar schlecht✨! 12 Jahre prekäre Beschäftigung & anschließend fliegen die nicht mehr ganz so jungen Wissenschaftler_innen ins Weltall 🚀 … ah Moment … doch nicht … sie fliegen: RAUS! Das sind Chancen!
#RundumSorglos #IchBinHanna
#RundumSorglos #IchBinHanna
June 5, 2025 at 6:39 PM
So ist es, liebes BMFTR: Die Chancen sind für jede Generation ✨vergleichbar schlecht✨! 12 Jahre prekäre Beschäftigung & anschließend fliegen die nicht mehr ganz so jungen Wissenschaftler_innen ins Weltall 🚀 … ah Moment … doch nicht … sie fliegen: RAUS! Das sind Chancen!
#RundumSorglos #IchBinHanna
#RundumSorglos #IchBinHanna
Reposted by Carsten Schulte
📜 A comprehensive strategy to strengthen bioimaging in Africa through the Africa Microscopy Initiative
🧑🔬 Michael Anton Reiche, Teng-Leong Chew, et al.
📔 Nature Cell Biology
🔗 www.nature.com/articles/s41...
#️⃣ (Feeds) #Microscopy #CellBiology #AfricaMicroscopyInitiative
🧑🔬 Michael Anton Reiche, Teng-Leong Chew, et al.
📔 Nature Cell Biology
🔗 www.nature.com/articles/s41...
#️⃣ (Feeds) #Microscopy #CellBiology #AfricaMicroscopyInitiative
A comprehensive strategy to strengthen bioimaging in Africa through the Africa Microscopy Initiative...
The Africa Microscopy Initiative (AMI) aims to promote the use of microscopy in biomedical research through facilitated access to instruments and expertise, and via training and networking opportuniti...
www.nature.com
November 2, 2023 at 3:02 PM
📜 A comprehensive strategy to strengthen bioimaging in Africa through the Africa Microscopy Initiative
🧑🔬 Michael Anton Reiche, Teng-Leong Chew, et al.
📔 Nature Cell Biology
🔗 www.nature.com/articles/s41...
#️⃣ (Feeds) #Microscopy #CellBiology #AfricaMicroscopyInitiative
🧑🔬 Michael Anton Reiche, Teng-Leong Chew, et al.
📔 Nature Cell Biology
🔗 www.nature.com/articles/s41...
#️⃣ (Feeds) #Microscopy #CellBiology #AfricaMicroscopyInitiative
Please RT and/or give me a name if you think someone from underrepresented countries deserves a forum:
#Science Bluesky, do your thing:
We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas.
Can you indicate some names to me?
We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas.
Can you indicate some names to me?
May 30, 2025 at 8:28 PM
Please RT and/or give me a name if you think someone from underrepresented countries deserves a forum:
#Science Bluesky, do your thing:
We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas.
Can you indicate some names to me?
We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas.
Can you indicate some names to me?
May 30, 2025 at 8:24 PM
#Science Bluesky, do your thing:
We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas.
Can you indicate some names to me?
We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas.
Can you indicate some names to me?
A brilliant idea that become a fantastic approach🤯:
Boom!!! 💥💥💥💥
EpiSci - 🧬 - 🧪 - Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation
@Zachary D. Chiang. @Ajay S.Labade @jbuenrostro.bsky.social
www.science.org/doi/10.1126/...
EpiSci - 🧬 - 🧪 - Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation
@Zachary D. Chiang. @Ajay S.Labade @jbuenrostro.bsky.social
www.science.org/doi/10.1126/...
Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation
Microscopy and genomics are used to characterize cell function, but approaches to connect the two types of information are lacking, particularly at subnuclear resolution. Here, we describe expansion i...
www.science.org
May 30, 2025 at 8:08 PM
A brilliant idea that become a fantastic approach🤯:
Reposted by Carsten Schulte
At the Center of the Cellular Microenvironment’s impact workshop. Really enjoying the space to think together about where cell engineering and mechanobiology are headed. @theglasgowcemi.bsky.social @unistrathclyde.bsky.social
May 29, 2025 at 10:35 AM
At the Center of the Cellular Microenvironment’s impact workshop. Really enjoying the space to think together about where cell engineering and mechanobiology are headed. @theglasgowcemi.bsky.social @unistrathclyde.bsky.social
Very important publication highlighting the need for more realistic cell culture disease models that recapitulate better (patho)physiological conditions.
YAP, a protein known to help #cancer cells survive treatment, behaves very differently in cell culture models depending on how they are grown in the lab, highlighting the importance of mimicking tumour architecture to guide better drug strategies.
buff.ly/KQ9bkLg
buff.ly/KQ9bkLg
May 18, 2025 at 4:52 PM
Very important publication highlighting the need for more realistic cell culture disease models that recapitulate better (patho)physiological conditions.
Reposted by Carsten Schulte
“The results revealed that researchers who received renewals without a funding gap were less likely to switch research topics and investigate a wide array of subjects than were those in the control group, and they produced papers featuring newer or more unconventional combinations of ideas”
Innovation takes time
US scientists who received renewals from the NIH over the past four decades produced more novel research than those who didn’t
https://go.nature.com/44s6cc5
US scientists who received renewals from the NIH over the past four decades produced more novel research than those who didn’t
https://go.nature.com/44s6cc5
Renewal of NIH grants linked to more innovative results, study finds
Nature - Survey of hundreds of scientists’ work suggests that cutting off funding disrupts focus and reduces the novelty of research.
go.nature.com
May 10, 2025 at 3:20 PM
“The results revealed that researchers who received renewals without a funding gap were less likely to switch research topics and investigate a wide array of subjects than were those in the control group, and they produced papers featuring newer or more unconventional combinations of ideas”
Retroactive or retrospective paper 🧵 (I like the term, thanks @nicopedroncelli.bsky.social):
A paper that I published as a co-first author in 2014 (with G.M. Ferraris and V. Buttiglione, supervised by N. Sidenius, not on bluesky) reached 100 citations.
Science social media weren't that big yet back then, so I seize this occasion to make a 🧵 about it now:
👉 www.embopress.org/doi/full/10....
Science social media weren't that big yet back then, so I seize this occasion to make a 🧵 about it now:
👉 www.embopress.org/doi/full/10....
The interaction between uPAR and vitronectin triggers ligand‐independent adhesion signalling by integrins | The EMBO Journal
image image Cell adhesion mediated by uPAR and other adhesion receptors triggers non‐canonical integrin activation independent
of integrin–ligand interactions. The cross‐talk between adhesion recepto...
www.embopress.org
May 6, 2025 at 3:53 PM
Retroactive or retrospective paper 🧵 (I like the term, thanks @nicopedroncelli.bsky.social):