Giuseppe Di Caprio
@giudica.bsky.social
Associate Professor (Senior Lecturer) at the University of Strathclyde. PI at CeMi. Interested in Smart Microscopy, Cell Engineering, Bioimage Analysis and Organs-On-Chip. Formerly Harvard and Federico II 🏳️🌈 📍Glasgow
https://dicaprio.bioe.strath.ac.uk
https://dicaprio.bioe.strath.ac.uk
Reposted by Giuseppe Di Caprio
What do ER exit sites really look like? Using large-scale volume FIB-SEM and a custom 3D-Unet pipeline (ASEM), Nahir et al @kirchhausenlab.bsky.social reveal that ERES are vesicular, abundant & diverse, resolving long-standing morphological discrepancies rupress.org/jcb/article/...
#ER_literature
#ER_literature
October 31, 2025 at 5:15 PM
What do ER exit sites really look like? Using large-scale volume FIB-SEM and a custom 3D-Unet pipeline (ASEM), Nahir et al @kirchhausenlab.bsky.social reveal that ERES are vesicular, abundant & diverse, resolving long-standing morphological discrepancies rupress.org/jcb/article/...
#ER_literature
#ER_literature
Reposted by Giuseppe Di Caprio
A beautiful piece of work from @ruixuan3.bsky.social and @supgokul.bsky.social presenting a light-based slicing method using a photosensitive hydrogel to image large biological samples layer by layer, preserving fine structure for full 3D reconstructions.
(1/x) Excited to report VIPS (Volumetric imaging of biological specimens via photochemical sectioning) @science.org! VIPS uses light-based sample sectioning to eliminate the inherent imaging depth limit of high-resolution optical microscopes @supgokul.bsky.social: www.science.org/doi/10.1126/...
Mesoscale volumetric fluorescence imaging at nanoscale resolution by photochemical sectioning
Optical nanoscopy of intact biological specimens has been transformed by recent advancements in hydrogel-based tissue clearing and expansion, enabling the imaging of cellular and subcellular structure...
www.science.org
October 17, 2025 at 3:52 PM
A beautiful piece of work from @ruixuan3.bsky.social and @supgokul.bsky.social presenting a light-based slicing method using a photosensitive hydrogel to image large biological samples layer by layer, preserving fine structure for full 3D reconstructions.
We’re excited to welcome Grant McClure, John Selkirk, Ben Polwart, and Robert Barry, who are undertaking their 5th-year Industrial Partnership Project on the OpenFlexure Microscope, an open-source, 3D-printed laboratory microscope designed to make high-quality microscopy accessible worldwide.
October 13, 2025 at 3:28 PM
We’re excited to welcome Grant McClure, John Selkirk, Ben Polwart, and Robert Barry, who are undertaking their 5th-year Industrial Partnership Project on the OpenFlexure Microscope, an open-source, 3D-printed laboratory microscope designed to make high-quality microscopy accessible worldwide.
Say Hi to Nicola👋🏻🔬, our shiny new Nikon microscope. Already the most popular member of the lab... Sorry everyone else 😅
September 30, 2025 at 4:19 PM
Say Hi to Nicola👋🏻🔬, our shiny new Nikon microscope. Already the most popular member of the lab... Sorry everyone else 😅
Reposted by Giuseppe Di Caprio
A new Perspective discusses the challenges of sharing annotated image datasets and offers advice for improving bioimage annotation and reuse, particularly for AI applications.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
September 17, 2025 at 2:56 PM
A new Perspective discusses the challenges of sharing annotated image datasets and offers advice for improving bioimage annotation and reuse, particularly for AI applications.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Giuseppe Di Caprio
Strathclyde named Scottish University of the Year and Runner-Up UK University of the Year by The Times and Sunday Times www.strath.ac.uk/whystrathcly...
September 19, 2025 at 8:51 AM
Strathclyde named Scottish University of the Year and Runner-Up UK University of the Year by The Times and Sunday Times www.strath.ac.uk/whystrathcly...
A bit of a terroristic view. Synthetic data isn’t all bad, it has been shown to improve classification algorithms.
P.S. We’ve got a hopefully interesting contribution to this field coming shortly. 📝 Stay tuned.
www.nature.com/articles/s41...
P.S. We’ve got a hopefully interesting contribution to this field coming shortly. 📝 Stay tuned.
www.nature.com/articles/s41...
The rising danger of AI-generated images in nanomaterials science and what we can do about it - Nature Nanotechnology
Generative AI has made it trivial to generate fake microscopy images that are indistinguishable from real images, even for experts. As researchers in nanoscience, it is time for us to face this realit...
www.nature.com
September 21, 2025 at 10:46 AM
A bit of a terroristic view. Synthetic data isn’t all bad, it has been shown to improve classification algorithms.
P.S. We’ve got a hopefully interesting contribution to this field coming shortly. 📝 Stay tuned.
www.nature.com/articles/s41...
P.S. We’ve got a hopefully interesting contribution to this field coming shortly. 📝 Stay tuned.
www.nature.com/articles/s41...
Big congrats to Lewis @lemackz.bsky.social and Pablo! @unistrathclyde.bsky.social www.heraldscotland.com/news/2547411...
Two Strathclyde Uni researchers receive grants worth more than £1.8m each
The two researchers have received grants worth more than £1.8m each
www.heraldscotland.com
September 20, 2025 at 6:20 PM
Big congrats to Lewis @lemackz.bsky.social and Pablo! @unistrathclyde.bsky.social www.heraldscotland.com/news/2547411...
IEEE is everywhere. 🤓 #IsleofKerrera
August 29, 2025 at 12:31 PM
IEEE is everywhere. 🤓 #IsleofKerrera
Reposted by Giuseppe Di Caprio
🔬🧠 Our paper on smart microscopy & the issue of interoperability! www.biorxiv.org/content/10.1... LONG THREAD WARNING: Smart microscopy uses real-time image analysis to automatically guide the acquisition or perturbation of the sample (closed feedback-control loop). Many applications exist:
August 21, 2025 at 2:22 PM
🔬🧠 Our paper on smart microscopy & the issue of interoperability! www.biorxiv.org/content/10.1... LONG THREAD WARNING: Smart microscopy uses real-time image analysis to automatically guide the acquisition or perturbation of the sample (closed feedback-control loop). Many applications exist:
Intrigued to know more about rBio, a new AI model from CZI that uses virtual cell models to explore biology in silico.
chanzuckerberg.com/blog/rbio-re...
chanzuckerberg.com/blog/rbio-re...
rBio: Reasoning Model Trained on Virtual Cell Simulations
Scientists can ask complex biological questions in plain language and get predictions about gene interactions.
chanzuckerberg.com
August 22, 2025 at 11:19 AM
Intrigued to know more about rBio, a new AI model from CZI that uses virtual cell models to explore biology in silico.
chanzuckerberg.com/blog/rbio-re...
chanzuckerberg.com/blog/rbio-re...
Reposted by Giuseppe Di Caprio
We just got a new toy 🔬🤓
August 21, 2025 at 11:04 AM
We just got a new toy 🔬🤓
So touched by this gift from our summer intern Grant McClure. Naturally, we ended up discussing how the architecture isn't quite correct... People do love feedback on their gifts, don't they 😅 #lifeofsheldon
August 18, 2025 at 1:06 PM
So touched by this gift from our summer intern Grant McClure. Naturally, we ended up discussing how the architecture isn't quite correct... People do love feedback on their gifts, don't they 😅 #lifeofsheldon
This sounds like a good idea: Instead of students submitting only a final PDF of their dissertation, have them submit with full version history. Makes AI use easier to spot, and you get to see their actual writing process. Could be a game‑changer for assessment.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Version control: how I combat the rise of generative AI in the classroom
I was worried that ChatGPT was composing my students’ essays. Looking at the writing process step by step can combat this and has other benefits, too.
www.nature.com
August 6, 2025 at 10:20 AM
This sounds like a good idea: Instead of students submitting only a final PDF of their dissertation, have them submit with full version history. Makes AI use easier to spot, and you get to see their actual writing process. Could be a game‑changer for assessment.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Grateful for the chance to speak on computational microscopy and ML/AI in imaging. Thanks for having me! #SOMC25 #Microscopy #AI
Our final lecture on Day 10 of #SOMC25 is on computational microscopy and ML/AI imaging/analysis approaches, delivered by @giudica.bsky.social (@strathbiomedeng.bsky.social).
August 1, 2025 at 2:15 PM
Grateful for the chance to speak on computational microscopy and ML/AI in imaging. Thanks for having me! #SOMC25 #Microscopy #AI
One of the MEng students in the group opened his project slides with an AI-generated image of me trying to break a CNN and honestly, it’s kind of perfect 🥹😂 So proud (and already slightly roasted).
June 25, 2025 at 2:15 PM
One of the MEng students in the group opened his project slides with an AI-generated image of me trying to break a CNN and honestly, it’s kind of perfect 🥹😂 So proud (and already slightly roasted).
New review paper out! Proud to co-author with @optophysakhil.bsky.social and @gailmcconnell.bsky.social a deep dive into Fourier Ptychographic Microscopy (FPM), from physics to cutting-edge algorithms & medical imaging applications. onlinelibrary.wiley.com/doi/epdf/10....
Fourier ptychography microscopy for digital pathology
onlinelibrary.wiley.com
June 24, 2025 at 12:23 PM
New review paper out! Proud to co-author with @optophysakhil.bsky.social and @gailmcconnell.bsky.social a deep dive into Fourier Ptychographic Microscopy (FPM), from physics to cutting-edge algorithms & medical imaging applications. onlinelibrary.wiley.com/doi/epdf/10....
Seriously need to know what magical places you all travel to have "limited email access".
June 19, 2025 at 11:03 PM
Seriously need to know what magical places you all travel to have "limited email access".
Reposted by Giuseppe Di Caprio
Out today in @natmethods.nature.com : Spotiflow, our transcript localization method for imaging-based spatial transcriptomics. Led by amazing PhD student @albertdm.bsky.social, joint work w @gioelelamanno.bsky.social at EPFL / @scadsai.bsky.social
www.nature.com/articles/s41...
rdcu.be/epIB7
www.nature.com/articles/s41...
rdcu.be/epIB7
June 6, 2025 at 7:06 PM
Out today in @natmethods.nature.com : Spotiflow, our transcript localization method for imaging-based spatial transcriptomics. Led by amazing PhD student @albertdm.bsky.social, joint work w @gioelelamanno.bsky.social at EPFL / @scadsai.bsky.social
www.nature.com/articles/s41...
rdcu.be/epIB7
www.nature.com/articles/s41...
rdcu.be/epIB7
Reposted by Giuseppe Di Caprio
As we mark #PrideMonth, we take this moment to celebrate LGBTQ+ identities and also reflect on the ongoing work to make our universities places where every member can thrive.
Thank you to colleagues for co-authoring this powerful piece on Rainbow Office Hours ➡️ gla.ac/3Zio6uv
#OneTeamUofG 🏳️🌈 🏳️⚧️
Thank you to colleagues for co-authoring this powerful piece on Rainbow Office Hours ➡️ gla.ac/3Zio6uv
#OneTeamUofG 🏳️🌈 🏳️⚧️
June 6, 2025 at 11:32 AM
As we mark #PrideMonth, we take this moment to celebrate LGBTQ+ identities and also reflect on the ongoing work to make our universities places where every member can thrive.
Thank you to colleagues for co-authoring this powerful piece on Rainbow Office Hours ➡️ gla.ac/3Zio6uv
#OneTeamUofG 🏳️🌈 🏳️⚧️
Thank you to colleagues for co-authoring this powerful piece on Rainbow Office Hours ➡️ gla.ac/3Zio6uv
#OneTeamUofG 🏳️🌈 🏳️⚧️
Research away day with a view. @unistrathclyde.bsky.social
June 4, 2025 at 11:56 AM
Research away day with a view. @unistrathclyde.bsky.social