Ruixuan Gao
@ruixuan3.bsky.social
Assistant Professor of Chemistry and Biological Sciences @UIC
Studying Neurobiology, Chemistry, Microscopy, and Nanoelectronics
Lab website: http://www.gaogroup.site/
Studying Neurobiology, Chemistry, Microscopy, and Nanoelectronics
Lab website: http://www.gaogroup.site/
Pinned
Ruixuan Gao
@ruixuan3.bsky.social
· Oct 17
Mesoscale volumetric fluorescence imaging at nanoscale resolution by photochemical sectioning
Optical nanoscopy of intact biological specimens has been transformed by recent advancements in hydrogel-based tissue clearing and expansion, enabling the imaging of cellular and subcellular structure...
www.science.org
(1/x) Excited to report VIPS (Volumetric imaging of biological specimens via photochemical sectioning) @science.org! VIPS uses light-based sample sectioning to eliminate the inherent imaging depth limit of high-resolution optical microscopes @supgokul.bsky.social: www.science.org/doi/10.1126/...
Have you wondered how alcohol affects your emotions and behavior in the long run? How does (excessive) alcohol exposure trigger changes in the brain at the molecular, cellular, and circuitry levels?
February 2, 2026 at 11:57 PM
Have you wondered how alcohol affects your emotions and behavior in the long run? How does (excessive) alcohol exposure trigger changes in the brain at the molecular, cellular, and circuitry levels?
Reposted by Ruixuan Gao
We have two funded postdoctoral positions available. Topics encompass:
-Next gen light-sheet fluorescence microscopy instrumentation
-Structured illumination microscopy and other approaches to extend the resolution limit.
-Nonlinear microscopy combined with adaptive optics / phase conjugation
-Next gen light-sheet fluorescence microscopy instrumentation
-Structured illumination microscopy and other approaches to extend the resolution limit.
-Nonlinear microscopy combined with adaptive optics / phase conjugation
January 27, 2026 at 10:29 PM
We have two funded postdoctoral positions available. Topics encompass:
-Next gen light-sheet fluorescence microscopy instrumentation
-Structured illumination microscopy and other approaches to extend the resolution limit.
-Nonlinear microscopy combined with adaptive optics / phase conjugation
-Next gen light-sheet fluorescence microscopy instrumentation
-Structured illumination microscopy and other approaches to extend the resolution limit.
-Nonlinear microscopy combined with adaptive optics / phase conjugation
Reposted by Ruixuan Gao
🔬🔦Check out our ‘Imaging spotlight’ on Volumetric Imaging via Photochemical Sectioning (VIPS) from @ruixuan3.bsky.social, Srigokul Upadhyayula and colleagues.
VIPS helps researchers scale super resolution imaging to large whole-mount tissues.
focalplane.biologists.com/2025/12/02/i...
VIPS helps researchers scale super resolution imaging to large whole-mount tissues.
focalplane.biologists.com/2025/12/02/i...
Imaging spotlight: Volumetric Imaging via Photochemical Sectioning (VIPS) - FocalPlane
Imaging spotlight: Volumetric Imaging via Photochemical Sectioning (VIPS) - Tools
focalplane.biologists.com
December 2, 2025 at 2:39 PM
🔬🔦Check out our ‘Imaging spotlight’ on Volumetric Imaging via Photochemical Sectioning (VIPS) from @ruixuan3.bsky.social, Srigokul Upadhyayula and colleagues.
VIPS helps researchers scale super resolution imaging to large whole-mount tissues.
focalplane.biologists.com/2025/12/02/i...
VIPS helps researchers scale super resolution imaging to large whole-mount tissues.
focalplane.biologists.com/2025/12/02/i...
Reposted by Ruixuan Gao
Thrilled to share our Science cover! VIPS (volumetric imaging via photochemical sectioning) eliminates working-distance limits for whole-mount, nanoscale imaging. LLSM + photodegradable hydrogel + petabyte-scale compute → mapped axons & myelin across two mouse olfactory bulbs (WT vs NPC1).
October 17, 2025 at 12:30 AM
Thrilled to share our Science cover! VIPS (volumetric imaging via photochemical sectioning) eliminates working-distance limits for whole-mount, nanoscale imaging. LLSM + photodegradable hydrogel + petabyte-scale compute → mapped axons & myelin across two mouse olfactory bulbs (WT vs NPC1).
Reposted by Ruixuan Gao
A new method called VIPS enables organ-wide nanoscale reconstruction for quantitative mapping of connectivity and molecular landscape in intact tissue.
Learn more this week in Science: https://scim.ag/4n4GKPm
Learn more this week in Science: https://scim.ag/4n4GKPm
October 16, 2025 at 6:05 PM
A new method called VIPS enables organ-wide nanoscale reconstruction for quantitative mapping of connectivity and molecular landscape in intact tissue.
Learn more this week in Science: https://scim.ag/4n4GKPm
Learn more this week in Science: https://scim.ag/4n4GKPm
(1/x) Excited to report VIPS (Volumetric imaging of biological specimens via photochemical sectioning) @science.org! VIPS uses light-based sample sectioning to eliminate the inherent imaging depth limit of high-resolution optical microscopes @supgokul.bsky.social: www.science.org/doi/10.1126/...
Mesoscale volumetric fluorescence imaging at nanoscale resolution by photochemical sectioning
Optical nanoscopy of intact biological specimens has been transformed by recent advancements in hydrogel-based tissue clearing and expansion, enabling the imaging of cellular and subcellular structure...
www.science.org
October 17, 2025 at 11:06 AM
(1/x) Excited to report VIPS (Volumetric imaging of biological specimens via photochemical sectioning) @science.org! VIPS uses light-based sample sectioning to eliminate the inherent imaging depth limit of high-resolution optical microscopes @supgokul.bsky.social: www.science.org/doi/10.1126/...