Ruixuan Gao
@ruixuan3.bsky.social
Assistant Professor of Chemistry and Biological Sciences @UIC
Studying Neurobiology, Chemistry, Microscopy, and Nanoelectronics
Lab website: http://www.gaogroup.site/
Studying Neurobiology, Chemistry, Microscopy, and Nanoelectronics
Lab website: http://www.gaogroup.site/
Pinned
Ruixuan Gao
@ruixuan3.bsky.social
· Oct 17
Mesoscale volumetric fluorescence imaging at nanoscale resolution by photochemical sectioning
Optical nanoscopy of intact biological specimens has been transformed by recent advancements in hydrogel-based tissue clearing and expansion, enabling the imaging of cellular and subcellular structure...
www.science.org
(1/x) Excited to report VIPS (Volumetric imaging of biological specimens via photochemical sectioning) @science.org! VIPS uses light-based sample sectioning to eliminate the inherent imaging depth limit of high-resolution optical microscopes @supgokul.bsky.social: www.science.org/doi/10.1126/...
Reposted by Ruixuan Gao
🔬🔦Check out our ‘Imaging spotlight’ on Volumetric Imaging via Photochemical Sectioning (VIPS) from @ruixuan3.bsky.social, Srigokul Upadhyayula and colleagues.
VIPS helps researchers scale super resolution imaging to large whole-mount tissues.
focalplane.biologists.com/2025/12/02/i...
VIPS helps researchers scale super resolution imaging to large whole-mount tissues.
focalplane.biologists.com/2025/12/02/i...
Imaging spotlight: Volumetric Imaging via Photochemical Sectioning (VIPS) - FocalPlane
Imaging spotlight: Volumetric Imaging via Photochemical Sectioning (VIPS) - Tools
focalplane.biologists.com
December 2, 2025 at 2:39 PM
🔬🔦Check out our ‘Imaging spotlight’ on Volumetric Imaging via Photochemical Sectioning (VIPS) from @ruixuan3.bsky.social, Srigokul Upadhyayula and colleagues.
VIPS helps researchers scale super resolution imaging to large whole-mount tissues.
focalplane.biologists.com/2025/12/02/i...
VIPS helps researchers scale super resolution imaging to large whole-mount tissues.
focalplane.biologists.com/2025/12/02/i...
Reposted by Ruixuan Gao
Thrilled to share our Science cover! VIPS (volumetric imaging via photochemical sectioning) eliminates working-distance limits for whole-mount, nanoscale imaging. LLSM + photodegradable hydrogel + petabyte-scale compute → mapped axons & myelin across two mouse olfactory bulbs (WT vs NPC1).
October 17, 2025 at 12:30 AM
Thrilled to share our Science cover! VIPS (volumetric imaging via photochemical sectioning) eliminates working-distance limits for whole-mount, nanoscale imaging. LLSM + photodegradable hydrogel + petabyte-scale compute → mapped axons & myelin across two mouse olfactory bulbs (WT vs NPC1).
Reposted by Ruixuan Gao
A new method called VIPS enables organ-wide nanoscale reconstruction for quantitative mapping of connectivity and molecular landscape in intact tissue.
Learn more this week in Science: https://scim.ag/4n4GKPm
Learn more this week in Science: https://scim.ag/4n4GKPm
October 16, 2025 at 6:05 PM
A new method called VIPS enables organ-wide nanoscale reconstruction for quantitative mapping of connectivity and molecular landscape in intact tissue.
Learn more this week in Science: https://scim.ag/4n4GKPm
Learn more this week in Science: https://scim.ag/4n4GKPm
(1/x) Excited to report VIPS (Volumetric imaging of biological specimens via photochemical sectioning) @science.org! VIPS uses light-based sample sectioning to eliminate the inherent imaging depth limit of high-resolution optical microscopes @supgokul.bsky.social: www.science.org/doi/10.1126/...
Mesoscale volumetric fluorescence imaging at nanoscale resolution by photochemical sectioning
Optical nanoscopy of intact biological specimens has been transformed by recent advancements in hydrogel-based tissue clearing and expansion, enabling the imaging of cellular and subcellular structure...
www.science.org
October 17, 2025 at 11:06 AM
(1/x) Excited to report VIPS (Volumetric imaging of biological specimens via photochemical sectioning) @science.org! VIPS uses light-based sample sectioning to eliminate the inherent imaging depth limit of high-resolution optical microscopes @supgokul.bsky.social: www.science.org/doi/10.1126/...