Carsten Schulte
@carstenschulte4.bsky.social
Interdisciplinary cell biologist fascinated by (extra)cellular mechanobiology in (patho)physiology. Lecturer, Department of Biomedical Engineering @University of Strathclyde & CeMi. Tweets about science & other stuff in which I engage. Views are my own.
Jane Goodall, one of my inspirations to study biology. What a big loss for humanity! RIP
October 3, 2025 at 3:24 PM
Jane Goodall, one of my inspirations to study biology. What a big loss for humanity! RIP
Glasgow representation is strong @cellmech2025.bsky.social with @unistrathclyde.bsky.social & @uofglasgow.bsky.social @theglasgowcemi.bsky.social cell mechanobiologists united 😊!
October 1, 2025 at 1:56 PM
Glasgow representation is strong @cellmech2025.bsky.social with @unistrathclyde.bsky.social & @uofglasgow.bsky.social @theglasgowcemi.bsky.social cell mechanobiologists united 😊!
On my way to CellMech25 in Leuven! I'm really looking forward to catching up with the Mechanobiology community! First time as Lecturer @unistrathclyde.bsky.social&PI @theglasgowcemi.bsky.social with parts of my group (Extra) Cellular Mechanobiology in Health and Disease @dylanjfowler.bsky.social 🤩!
September 29, 2025 at 8:18 AM
On my way to CellMech25 in Leuven! I'm really looking forward to catching up with the Mechanobiology community! First time as Lecturer @unistrathclyde.bsky.social&PI @theglasgowcemi.bsky.social with parts of my group (Extra) Cellular Mechanobiology in Health and Disease @dylanjfowler.bsky.social 🤩!
The core team of the Tenovus Scotland-funded Small Pilot Grant project "Leveraging mechanobiology for the optimisation of in vitro muscle-related disease models" is on the case😊, with a strong 4th&5th year students-driven component! @unistrathclyde.bsky.social @theglasgowcemi.bsky.social
September 22, 2025 at 10:29 PM
The core team of the Tenovus Scotland-funded Small Pilot Grant project "Leveraging mechanobiology for the optimisation of in vitro muscle-related disease models" is on the case😊, with a strong 4th&5th year students-driven component! @unistrathclyde.bsky.social @theglasgowcemi.bsky.social
We are very happy 😄 that our Rheinland-Pfalz & Scotland exchange project started, jointly awarded by @sulsa.bsky.social and JGU Scotland Hub, sponsored by the governments of 🏴 & Rheinland-Pfalz. 1/2
@unistrathclyde.bsky.social @theglasgowcemi.bsky.social @imbmainz.bsky.social @unimainz.bsky.social
@unistrathclyde.bsky.social @theglasgowcemi.bsky.social @imbmainz.bsky.social @unimainz.bsky.social
September 10, 2025 at 8:17 PM
We are very happy 😄 that our Rheinland-Pfalz & Scotland exchange project started, jointly awarded by @sulsa.bsky.social and JGU Scotland Hub, sponsored by the governments of 🏴 & Rheinland-Pfalz. 1/2
@unistrathclyde.bsky.social @theglasgowcemi.bsky.social @imbmainz.bsky.social @unimainz.bsky.social
@unistrathclyde.bsky.social @theglasgowcemi.bsky.social @imbmainz.bsky.social @unimainz.bsky.social
BioMedEng25 is over! I really enjoyed my talk&the opportunity present my research. I also talked about unpublished work from a collaboration with @carmeloferrai.bsky.social that is getting closer&closer to being deposited on @biorxivpreprint.bsky.social. Stay tuned 😀!
@biomedeng25.bsky.social
@biomedeng25.bsky.social
September 5, 2025 at 4:42 PM
BioMedEng25 is over! I really enjoyed my talk&the opportunity present my research. I also talked about unpublished work from a collaboration with @carmeloferrai.bsky.social that is getting closer&closer to being deposited on @biorxivpreprint.bsky.social. Stay tuned 😀!
@biomedeng25.bsky.social
@biomedeng25.bsky.social
#Science Bluesky, do your thing:
We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas.
Can you indicate some names to me?
We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas.
Can you indicate some names to me?
May 30, 2025 at 8:24 PM
#Science Bluesky, do your thing:
We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas.
Can you indicate some names to me?
We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas.
Can you indicate some names to me?
...can involve also other cell adhesion receptors (e.g., GPI-anchored, such as uPAR, or maybe syndecans, DDRs?) 2/2:
May 6, 2025 at 3:50 PM
...can involve also other cell adhesion receptors (e.g., GPI-anchored, such as uPAR, or maybe syndecans, DDRs?) 2/2:
I delved even deeper into this a few years later, further highlighting the importance of talin-mediated molecular clutch force loading in this process:
👉 www.sciencedirect.com/science/arti...
👉 www.sciencedirect.com/science/arti...
May 6, 2025 at 3:08 PM
I delved even deeper into this a few years later, further highlighting the importance of talin-mediated molecular clutch force loading in this process:
👉 www.sciencedirect.com/science/arti...
👉 www.sciencedirect.com/science/arti...
This ligand binding-independent integrin signalling was driven by membrane tension. Indeed, the induction of this non-canonical integrin signalling was not restricted to uPAR/vitronectin interaction.
This work introduced the cell membrane as a critical component of the molecular clutch.
This work introduced the cell membrane as a critical component of the molecular clutch.
May 6, 2025 at 2:56 PM
This ligand binding-independent integrin signalling was driven by membrane tension. Indeed, the induction of this non-canonical integrin signalling was not restricted to uPAR/vitronectin interaction.
This work introduced the cell membrane as a critical component of the molecular clutch.
This work introduced the cell membrane as a critical component of the molecular clutch.
This study assessed the possibility of ligand-independent adhesion signalling by integrins, which was a quite controversial hypothesis at the time (maybe still is).
We found that e.g. uPAR-mediated adhesion to vitronectin can induce integrin signalling that does not require integrin ligand binding:
We found that e.g. uPAR-mediated adhesion to vitronectin can induce integrin signalling that does not require integrin ligand binding:
May 6, 2025 at 2:43 PM
This study assessed the possibility of ligand-independent adhesion signalling by integrins, which was a quite controversial hypothesis at the time (maybe still is).
We found that e.g. uPAR-mediated adhesion to vitronectin can induce integrin signalling that does not require integrin ligand binding:
We found that e.g. uPAR-mediated adhesion to vitronectin can induce integrin signalling that does not require integrin ligand binding:
The abstract submission deadline of BioMedGen2025 @biomedeng25.bsky.social has been extended. You still have the chance to submit until the 19th of May. Meet us all in Glasgow😊:
👉 biomedeng.org/biomedeng25/
👉 biomedeng.org/biomedeng25/
May 6, 2025 at 2:15 PM
The abstract submission deadline of BioMedGen2025 @biomedeng25.bsky.social has been extended. You still have the chance to submit until the 19th of May. Meet us all in Glasgow😊:
👉 biomedeng.org/biomedeng25/
👉 biomedeng.org/biomedeng25/
This review on mechanotransduction in neuronal cells that I wrote in 2019, together with Matteo Chighizola, Tania Dini, Cristina Lenardi, Paolo Milani and Alessandro Podesta' (all not yet on bluesky), reached 100 citations😊🎇, would have never thought it back then:
👉 link.springer.com/article/10.1...
👉 link.springer.com/article/10.1...
March 18, 2025 at 5:38 PM
This review on mechanotransduction in neuronal cells that I wrote in 2019, together with Matteo Chighizola, Tania Dini, Cristina Lenardi, Paolo Milani and Alessandro Podesta' (all not yet on bluesky), reached 100 citations😊🎇, would have never thought it back then:
👉 link.springer.com/article/10.1...
👉 link.springer.com/article/10.1...
If you are interested in these aspects in other cell biological contexts, have a look at my two reviews on mechanotransduction in neuronal and stem cells:
👉 link.springer.com/article/10.1...
👉 www.sciencedirect.com/science/arti...
@carmeloferrai@bsky.social
👉 link.springer.com/article/10.1...
👉 www.sciencedirect.com/science/arti...
@carmeloferrai@bsky.social
March 7, 2025 at 6:11 PM
If you are interested in these aspects in other cell biological contexts, have a look at my two reviews on mechanotransduction in neuronal and stem cells:
👉 link.springer.com/article/10.1...
👉 www.sciencedirect.com/science/arti...
@carmeloferrai@bsky.social
👉 link.springer.com/article/10.1...
👉 www.sciencedirect.com/science/arti...
@carmeloferrai@bsky.social
Yesterday, we had the great pleasure to host @merrylabnotts.bsky.social at our Department @unistrathclyde.bsky.social. Thanks for your amazing talk about the wonderful world of the glycocalyx! Thanks, in particular, also for great conversations about science and so much more☺️!
February 20, 2025 at 9:29 AM
Yesterday, we had the great pleasure to host @merrylabnotts.bsky.social at our Department @unistrathclyde.bsky.social. Thanks for your amazing talk about the wonderful world of the glycocalyx! Thanks, in particular, also for great conversations about science and so much more☺️!
It was a great joy to meet a considerable portion of the Mechanobiology community in London recently! Great conference with really nice talks & very interesting discussions.
The European Mechanobiology community is alive & kicking.
Special thanks to @massivassi.bsky.social for organising this event!
The European Mechanobiology community is alive & kicking.
Special thanks to @massivassi.bsky.social for organising this event!
December 6, 2024 at 4:39 PM
It was a great joy to meet a considerable portion of the Mechanobiology community in London recently! Great conference with really nice talks & very interesting discussions.
The European Mechanobiology community is alive & kicking.
Special thanks to @massivassi.bsky.social for organising this event!
The European Mechanobiology community is alive & kicking.
Special thanks to @massivassi.bsky.social for organising this event!
My Google scholar word cloud😊 (made with www.scholargoggler.com):
November 22, 2024 at 2:33 PM
My Google scholar word cloud😊 (made with www.scholargoggler.com):
A few days ago, I gave my first lecture at the Department of Biomedical Engineering of the University of Strathclyde. I guess, I can call myself officially and practically a lecturer now 🤣:
November 14, 2024 at 12:09 PM
A few days ago, I gave my first lecture at the Department of Biomedical Engineering of the University of Strathclyde. I guess, I can call myself officially and practically a lecturer now 🤣:
Applications are OPEN for our (me, Miguel Pineda and Nikolaj Gardegaard) NorthWestBio DTP opportunity "Breaking the Code of Inflammation: How Cells Sense and Respond to Physical Signals."
Have a look 👀 , and please contact me for informal enquiries, or apply here 😊 :
www.gla.ac.uk/postgraduate...
Have a look 👀 , and please contact me for informal enquiries, or apply here 😊 :
www.gla.ac.uk/postgraduate...
November 13, 2024 at 2:55 PM
Applications are OPEN for our (me, Miguel Pineda and Nikolaj Gardegaard) NorthWestBio DTP opportunity "Breaking the Code of Inflammation: How Cells Sense and Respond to Physical Signals."
Have a look 👀 , and please contact me for informal enquiries, or apply here 😊 :
www.gla.ac.uk/postgraduate...
Have a look 👀 , and please contact me for informal enquiries, or apply here 😊 :
www.gla.ac.uk/postgraduate...
Thanks Carmelo, indeed, I think the work by Zhang et al. of the Cui group&our work you cited here, are nicely complementary covering different aspects of cellular nanotopography mechanosensing. I would also add our previous work: 👉https://pubs.rsc.org/en/content/articlelanding/2020/nr/d0nr01991g
October 16, 2023 at 9:20 AM
Thanks Carmelo, indeed, I think the work by Zhang et al. of the Cui group&our work you cited here, are nicely complementary covering different aspects of cellular nanotopography mechanosensing. I would also add our previous work: 👉https://pubs.rsc.org/en/content/articlelanding/2020/nr/d0nr01991g
This highly interdisciplinary work started as a somewhat "crazy idea" between biologists and physicists at the Phys2BioMed network and was brilliantly realised by
Hatice Holuigue, involving groups at the University of Milan, IEO and San Raffaele.
.
Hatice Holuigue, involving groups at the University of Milan, IEO and San Raffaele.
.
October 9, 2023 at 8:55 AM
This highly interdisciplinary work started as a somewhat "crazy idea" between biologists and physicists at the Phys2BioMed network and was brilliantly realised by
Hatice Holuigue, involving groups at the University of Milan, IEO and San Raffaele.
.
Hatice Holuigue, involving groups at the University of Milan, IEO and San Raffaele.
.
My first post on bluesky is dedicated to our new publication:
Measuring cellular adhesion to real ECM with piconewton precision of atomic force microscopy? We show how this can be achieved by a novel and versatile approach:
👉https://pubs.rsc.org/en/content/articlelanding/2023/NR/D3NR01568H
Measuring cellular adhesion to real ECM with piconewton precision of atomic force microscopy? We show how this can be achieved by a novel and versatile approach:
👉https://pubs.rsc.org/en/content/articlelanding/2023/NR/D3NR01568H
October 9, 2023 at 8:24 AM
My first post on bluesky is dedicated to our new publication:
Measuring cellular adhesion to real ECM with piconewton precision of atomic force microscopy? We show how this can be achieved by a novel and versatile approach:
👉https://pubs.rsc.org/en/content/articlelanding/2023/NR/D3NR01568H
Measuring cellular adhesion to real ECM with piconewton precision of atomic force microscopy? We show how this can be achieved by a novel and versatile approach:
👉https://pubs.rsc.org/en/content/articlelanding/2023/NR/D3NR01568H