Kyojiro N Ikeda
@beingkyo.bsky.social
Submicron morphogenesis
Postdoc at University of Vienna @univie.ac.at
Postdoc at University of Vienna @univie.ac.at
Reposted by Kyojiro N Ikeda
Congrats🥳 to @mike-wieczorek.bsky.social, Bin Cai, and our former lab member Jingwei Xu @xujwet.bsky.social to their multiscale imaging 🔬 story of the centriolar AC linker #teamtomo
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Structure and assembly of the A-C linker connecting microtubule triplets in centrioles
Multiscale cryo-EM of centrioles reveals the structure and polymorphism of the A-C linker connecting microtubule triplets.
www.science.org
October 8, 2025 at 7:07 PM
Congrats🥳 to @mike-wieczorek.bsky.social, Bin Cai, and our former lab member Jingwei Xu @xujwet.bsky.social to their multiscale imaging 🔬 story of the centriolar AC linker #teamtomo
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Kyojiro N Ikeda
What would happen if cells would express more molecular motors ?
They would break all microtubules 😱
As shown by recent great work from @kjverhey1.bsky.social
rupress.org/jcb/article-...
They would break all microtubules 😱
As shown by recent great work from @kjverhey1.bsky.social
rupress.org/jcb/article-...
October 7, 2025 at 3:08 PM
What would happen if cells would express more molecular motors ?
They would break all microtubules 😱
As shown by recent great work from @kjverhey1.bsky.social
rupress.org/jcb/article-...
They would break all microtubules 😱
As shown by recent great work from @kjverhey1.bsky.social
rupress.org/jcb/article-...
Reposted by Kyojiro N Ikeda
Latest from ours: www.cell.com/cell-reports...
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
October 5, 2025 at 10:35 AM
Latest from ours: www.cell.com/cell-reports...
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
Reposted by Kyojiro N Ikeda
A molecular-resolution look into the near-native architecture of the spinach chloroplast🌱. This one was a long time in the oven, but we're happy to finally share our "version of record". What long-standing debates did we settle? Check back for a short thread🧵 on Monday. #TeamTomo #PlantScience 🧪🧶🧬🔬🌾
🌱 Using ‘compelling’ methods, including #CryoET, researchers mapped spinach thylakoid membranes at single-molecule precision, revealing how photosynthetic complexes are organised and settling long-standing debates on chloroplast architecture.
buff.ly/j3TSIkn
buff.ly/j3TSIkn
September 20, 2025 at 7:24 PM
A molecular-resolution look into the near-native architecture of the spinach chloroplast🌱. This one was a long time in the oven, but we're happy to finally share our "version of record". What long-standing debates did we settle? Check back for a short thread🧵 on Monday. #TeamTomo #PlantScience 🧪🧶🧬🔬🌾
Reposted by Kyojiro N Ikeda
Our new paper is out in @currentbiology.bsky.social! Using 3D reconstructions and volume measurements in Drosophila wing primordia, we show that growth can be uncoupled from cell proliferation and uncover a new time window for growth arrest.
With @leopoldlab.bsky.social
www.cell.com/current-biol...
With @leopoldlab.bsky.social
www.cell.com/current-biol...
A switch to non-proliferative growth sustains Drosophila wing development during the early pupal stage
Using precise tissue volume quantification, El Marzkioui, Gaugué, et al. show that
wing primordia continue to grow during the early pupal stage, a phase of increased
cell volume driven by insulin/IGF ...
www.cell.com
August 10, 2025 at 3:01 PM
Our new paper is out in @currentbiology.bsky.social! Using 3D reconstructions and volume measurements in Drosophila wing primordia, we show that growth can be uncoupled from cell proliferation and uncover a new time window for growth arrest.
With @leopoldlab.bsky.social
www.cell.com/current-biol...
With @leopoldlab.bsky.social
www.cell.com/current-biol...
Reposted by Kyojiro N Ikeda
Very proud to share our latest preprint: postdoc/LRSF fellow Yue Rui studies the mechanisms regulating attachment of the cell wall to the plasma membrane. The Cellulose Synthase Complex and REMORINs determine the extent of attachment and root osmotic stress tolerance. www.biorxiv.org/content/10.1...
August 3, 2025 at 3:53 AM
Very proud to share our latest preprint: postdoc/LRSF fellow Yue Rui studies the mechanisms regulating attachment of the cell wall to the plasma membrane. The Cellulose Synthase Complex and REMORINs determine the extent of attachment and root osmotic stress tolerance. www.biorxiv.org/content/10.1...
Reposted by Kyojiro N Ikeda
An amoeba with teeth. When building its shell, Netzelia corona selects sharp grains of quartz and positions them around its aperture with the tips pointing inward. I took a few closeups, yesterday. #ProtistsonSky #amoebae #peatlands #MEvoSky
May 31, 2025 at 8:33 PM
An amoeba with teeth. When building its shell, Netzelia corona selects sharp grains of quartz and positions them around its aperture with the tips pointing inward. I took a few closeups, yesterday. #ProtistsonSky #amoebae #peatlands #MEvoSky
Reposted by Kyojiro N Ikeda
One protein, two opposing roles: This ‘compelling’ study shows how the same signalling molecule can drive either protrusion or retraction in migrating cells depending on its concentration and activation dynamics.
elifesciences.org/articles/931...
elifesciences.org/articles/931...
July 15, 2025 at 10:02 AM
One protein, two opposing roles: This ‘compelling’ study shows how the same signalling molecule can drive either protrusion or retraction in migrating cells depending on its concentration and activation dynamics.
elifesciences.org/articles/931...
elifesciences.org/articles/931...
Reposted by Kyojiro N Ikeda
Belyantseva and Liu et al. report that taperin encircles and stabilizes F-#actin at auditory hair cell #stereocilia bases and bundles F-actin. Taperin deficiency causes stereocilia disassembly, rootlet breakage at pivots, and other abnormalities culminating in deafness. rupress.org/jcb/article/...
June 5, 2025 at 4:18 PM
Belyantseva and Liu et al. report that taperin encircles and stabilizes F-#actin at auditory hair cell #stereocilia bases and bundles F-actin. Taperin deficiency causes stereocilia disassembly, rootlet breakage at pivots, and other abnormalities culminating in deafness. rupress.org/jcb/article/...
I can say that I lived in the times of CRISPR. - @jenniferdoudna.bsky.social 's talk at @gmivienna.bsky.social 25th year anniversary jubilee at ÖAW.
May 5, 2025 at 8:31 PM
I can say that I lived in the times of CRISPR. - @jenniferdoudna.bsky.social 's talk at @gmivienna.bsky.social 25th year anniversary jubilee at ÖAW.
Reposted by Kyojiro N Ikeda
#DevBio job opportunity!
Development (@dev-journal.bsky.social) is looking for a new Community Manager to run our community site, the Node (@the-node.bsky.social) – a great opportunity if you love devbio, #stemcells, #scicom and community engagement. Happy to chat informally about the role.
⬇️
Development (@dev-journal.bsky.social) is looking for a new Community Manager to run our community site, the Node (@the-node.bsky.social) – a great opportunity if you love devbio, #stemcells, #scicom and community engagement. Happy to chat informally about the role.
⬇️
Work for us
Working for us We’re always looking for talented and motivated people to work as part of our close-knit team. Roles range from editorial to production, marketing to event co-ordination, HR to accounts...
www.biologists.com
April 23, 2025 at 3:12 PM
#DevBio job opportunity!
Development (@dev-journal.bsky.social) is looking for a new Community Manager to run our community site, the Node (@the-node.bsky.social) – a great opportunity if you love devbio, #stemcells, #scicom and community engagement. Happy to chat informally about the role.
⬇️
Development (@dev-journal.bsky.social) is looking for a new Community Manager to run our community site, the Node (@the-node.bsky.social) – a great opportunity if you love devbio, #stemcells, #scicom and community engagement. Happy to chat informally about the role.
⬇️
Reposted by Kyojiro N Ikeda
I’ve just updated the BioEmu notebook to include the powerful LogMD. Now, you can generate equilibrium ensembles and explore the full ensemble directly in the notebook.
A huge thanks to Alexander Mathiasen for the support! 🙌
🔗 Try it on Google Colab: lnkd.in/gcuqd-fT
A huge thanks to Alexander Mathiasen for the support! 🙌
🔗 Try it on Google Colab: lnkd.in/gcuqd-fT
March 20, 2025 at 6:09 PM
I’ve just updated the BioEmu notebook to include the powerful LogMD. Now, you can generate equilibrium ensembles and explore the full ensemble directly in the notebook.
A huge thanks to Alexander Mathiasen for the support! 🙌
🔗 Try it on Google Colab: lnkd.in/gcuqd-fT
A huge thanks to Alexander Mathiasen for the support! 🙌
🔗 Try it on Google Colab: lnkd.in/gcuqd-fT
Reposted by Kyojiro N Ikeda
Kyojiro Ikeda @beingkyo.bsky.social @univie.ac.at presenting now at #DevStem2025 @viennabiocenter.bsky.social on first mechanistic & molecular regulators of #bristle biogenesis in the #Platynereis model. Also check Kyojiro's recent @naturecomms.bsky.social publication www.nature.com/articles/s41...
April 4, 2025 at 10:46 AM
Kyojiro Ikeda @beingkyo.bsky.social @univie.ac.at presenting now at #DevStem2025 @viennabiocenter.bsky.social on first mechanistic & molecular regulators of #bristle biogenesis in the #Platynereis model. Also check Kyojiro's recent @naturecomms.bsky.social publication www.nature.com/articles/s41...
Reposted by Kyojiro N Ikeda
Are you in for a PhD project on neural #regeneration? Only 2 more weeks to apply to the @vbcscitraining.bsky.social @univie.ac.at VBC PhD programme: vbcphd.at ! Pls. see tiny.cc/RaibleLab and our recent @naturecomms.bsky.social study www.nature.com/articles/s41... for information and contact!
April 1, 2025 at 2:57 PM
Are you in for a PhD project on neural #regeneration? Only 2 more weeks to apply to the @vbcscitraining.bsky.social @univie.ac.at VBC PhD programme: vbcphd.at ! Pls. see tiny.cc/RaibleLab and our recent @naturecomms.bsky.social study www.nature.com/articles/s41... for information and contact!
Reposted by Kyojiro N Ikeda
Take the next step in your academic career and become part of a thriving international research community!
The Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences (VDS-PhaNuSpo) are offering 13 fully four-year funded PhD positions at the moment!
The Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences (VDS-PhaNuSpo) are offering 13 fully four-year funded PhD positions at the moment!
Open positions
Open positions
vds-phanuspo.univie.ac.at
April 1, 2025 at 1:36 PM
Take the next step in your academic career and become part of a thriving international research community!
The Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences (VDS-PhaNuSpo) are offering 13 fully four-year funded PhD positions at the moment!
The Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences (VDS-PhaNuSpo) are offering 13 fully four-year funded PhD positions at the moment!
Reposted by Kyojiro N Ikeda
Incredible 4Pi and pan-expansion imaging of the Golgi 👇
March 29, 2025 at 4:03 PM
Incredible 4Pi and pan-expansion imaging of the Golgi 👇
Reposted by Kyojiro N Ikeda
We're on the cover of @science.org this week. Awesome work by @florentwaltz.bsky.social. #CryoET is reaching crazy resolutions inside cells, and this is just the beginning. Fantastic interpretation of the proton motive force by @verenaresch.bsky.social. Always a pleasure making #SciArt with you!🧪🧶🧬🌾
In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion.
Learn more in this week's issue: scim.ag/3FA3Ygq
Learn more in this week's issue: scim.ag/3FA3Ygq
March 20, 2025 at 10:37 PM
We're on the cover of @science.org this week. Awesome work by @florentwaltz.bsky.social. #CryoET is reaching crazy resolutions inside cells, and this is just the beginning. Fantastic interpretation of the proton motive force by @verenaresch.bsky.social. Always a pleasure making #SciArt with you!🧪🧶🧬🌾
Reposted by Kyojiro N Ikeda
Nature research paper: Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium
https://go.nature.com/4hrHX0v
https://go.nature.com/4hrHX0v
Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium - Nature
Dynamic cytoskeletal regulation of lymphatic endothelial cell shape, induced by isotropic stretch and crucial for dermal lymphatic capillary function, is identified and found to result from continuous remodelling of cellular overlaps that maintain vessel integrity.
go.nature.com
March 20, 2025 at 1:30 PM
Nature research paper: Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium
https://go.nature.com/4hrHX0v
https://go.nature.com/4hrHX0v
Reposted by Kyojiro N Ikeda
My continued biological education
#Mechanobiology #RigiditySensing
Stiffness Sensing by Cells
"Substrate Stiffness Can Lead to Heritable Epigenetic Changes"
"Cell Motility Is Faster on Soft Elastic Substrates"
#PhysiolRev 2020
journals.physiology.org/doi/full/10....
#Mechanobiology #RigiditySensing
Stiffness Sensing by Cells
"Substrate Stiffness Can Lead to Heritable Epigenetic Changes"
"Cell Motility Is Faster on Soft Elastic Substrates"
#PhysiolRev 2020
journals.physiology.org/doi/full/10....
March 2, 2025 at 12:25 PM
My continued biological education
#Mechanobiology #RigiditySensing
Stiffness Sensing by Cells
"Substrate Stiffness Can Lead to Heritable Epigenetic Changes"
"Cell Motility Is Faster on Soft Elastic Substrates"
#PhysiolRev 2020
journals.physiology.org/doi/full/10....
#Mechanobiology #RigiditySensing
Stiffness Sensing by Cells
"Substrate Stiffness Can Lead to Heritable Epigenetic Changes"
"Cell Motility Is Faster on Soft Elastic Substrates"
#PhysiolRev 2020
journals.physiology.org/doi/full/10....
Reposted by Kyojiro N Ikeda
Cool story on nanopatters! We had picked Osiris genes as erect wing regulated, but no clue what this was about.
genomebiology.biomedcentral.com/articles/10....
genomebiology.biomedcentral.com/articles/10....
February 12, 2025 at 9:14 AM
Cool story on nanopatters! We had picked Osiris genes as erect wing regulated, but no clue what this was about.
genomebiology.biomedcentral.com/articles/10....
genomebiology.biomedcentral.com/articles/10....
Reposted by Kyojiro N Ikeda
Can you spot the difference? 🔬
SiR-actin labeling can be cytotoxic and affects actin dynamics - while the new XActin probes do not! Developed by @veselin-nasufovic.bsky.social and perfect for time-resolved and STED imaging without the need for genetic manipulation.
www.biorxiv.org/content/10.1...
SiR-actin labeling can be cytotoxic and affects actin dynamics - while the new XActin probes do not! Developed by @veselin-nasufovic.bsky.social and perfect for time-resolved and STED imaging without the need for genetic manipulation.
www.biorxiv.org/content/10.1...
February 7, 2025 at 10:14 AM
Can you spot the difference? 🔬
SiR-actin labeling can be cytotoxic and affects actin dynamics - while the new XActin probes do not! Developed by @veselin-nasufovic.bsky.social and perfect for time-resolved and STED imaging without the need for genetic manipulation.
www.biorxiv.org/content/10.1...
SiR-actin labeling can be cytotoxic and affects actin dynamics - while the new XActin probes do not! Developed by @veselin-nasufovic.bsky.social and perfect for time-resolved and STED imaging without the need for genetic manipulation.
www.biorxiv.org/content/10.1...
Reposted by Kyojiro N Ikeda
First Post! Thrilled to share our lab's first evolutionary cytoskeleton study! We uncover two distinct FtsZ paralogs in Odinarchaeota OdinFtsZ1 forms curved filaments, while OdinFtsZ2 assembles into spiral rings. A glimpse into tubulin evolution! threads👇 #Eukaryogenesis #AsgardArchaea #cytoskeleton
February 4, 2025 at 5:55 AM
First Post! Thrilled to share our lab's first evolutionary cytoskeleton study! We uncover two distinct FtsZ paralogs in Odinarchaeota OdinFtsZ1 forms curved filaments, while OdinFtsZ2 assembles into spiral rings. A glimpse into tubulin evolution! threads👇 #Eukaryogenesis #AsgardArchaea #cytoskeleton
Reposted by Kyojiro N Ikeda
Huge congrats to Nadja Milivojev @vbcscitraining.bsky.social who successfully defended her @univie.ac.at PhD thesis with a brilliant presentation today. Thanks to examiners Elly Tanaka, Michael @mikebok.bsky.social and Roger Revilla, and both labs for wonderful support!
January 31, 2025 at 4:14 PM
Huge congrats to Nadja Milivojev @vbcscitraining.bsky.social who successfully defended her @univie.ac.at PhD thesis with a brilliant presentation today. Thanks to examiners Elly Tanaka, Michael @mikebok.bsky.social and Roger Revilla, and both labs for wonderful support!