Philippe Bastin's Lab
@bastinlab.bsky.social
Research unit @Institut Pasteur & @Inserm dealing with trypanosomes, cilia and flagella, tsetse flies, intraflagellar transport, imaging by light and electron microscopy,...
https://research.pasteur.fr/en/team/trypanosome-cell-biology/
https://research.pasteur.fr/en/team/trypanosome-cell-biology/
Reposted by Philippe Bastin's Lab
We miss him so much...
🔬 Honoring Spencer Shorte's legacy
Jan 28, 2026 Institut Pasteur symposium celebrating a pioneering figure in bioimaging & core facilities.
Scientists worldwide will share how his visionary work continues to shape research.
Free registration: forms.cloud.microsoft/pages/respon...
Jan 28, 2026 Institut Pasteur symposium celebrating a pioneering figure in bioimaging & core facilities.
Scientists worldwide will share how his visionary work continues to shape research.
Free registration: forms.cloud.microsoft/pages/respon...
December 16, 2025 at 11:17 AM
We miss him so much...
Reposted by Philippe Bastin's Lab
The MOOC “Viral Outbreaks and Pandemics” starts in one month ! 👉Register ! bit.ly/3tbey7I and share !
Why viral outbreaks are becoming more frequent ? How the world is learning to manage emerging infections in a one health approach?
👥 Discover with A Fontanet, JP Vartanian, PE Ceccaldi, S Zientara
Why viral outbreaks are becoming more frequent ? How the world is learning to manage emerging infections in a one health approach?
👥 Discover with A Fontanet, JP Vartanian, PE Ceccaldi, S Zientara
December 15, 2025 at 9:37 AM
The MOOC “Viral Outbreaks and Pandemics” starts in one month ! 👉Register ! bit.ly/3tbey7I and share !
Why viral outbreaks are becoming more frequent ? How the world is learning to manage emerging infections in a one health approach?
👥 Discover with A Fontanet, JP Vartanian, PE Ceccaldi, S Zientara
Why viral outbreaks are becoming more frequent ? How the world is learning to manage emerging infections in a one health approach?
👥 Discover with A Fontanet, JP Vartanian, PE Ceccaldi, S Zientara
Lovely study! Congratulations to all involved! 👏👏👏
How does C2CD3 contribute to distal appendage formation in centrioles? @centriolelab.bsky.social show that C2CD3 acts as a central architectural organizer of the distal #centriole, bridging the luminal distal ring complex & peripheral appendage sites @plosbiology.org 🧪 plos.io/496XZuH
December 10, 2025 at 1:24 PM
Lovely study! Congratulations to all involved! 👏👏👏
Congratulations to Christine for being awarded the silver "médaille d'honneur du travail"! 👏👏👏 @pasteur.fr
December 10, 2025 at 7:34 AM
Congratulations to Christine for being awarded the silver "médaille d'honneur du travail"! 👏👏👏 @pasteur.fr
Reposted by Philippe Bastin's Lab
🔬 Call to create junior research groups at the Institut Pasteur
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research
The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...
research.pasteur.fr
December 8, 2025 at 8:53 AM
🔬 Call to create junior research groups at the Institut Pasteur
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Reposted by Philippe Bastin's Lab
After a year of inspiring scientific exchanges, the ParaFrap Webinars return in 2026!
Explore the full calendar of cutting-edge parasitology talks and join the community of curious minds
👉 labex-parafrap.fr/en/conferenc...
Explore the full calendar of cutting-edge parasitology talks and join the community of curious minds
👉 labex-parafrap.fr/en/conferenc...
December 8, 2025 at 10:29 AM
After a year of inspiring scientific exchanges, the ParaFrap Webinars return in 2026!
Explore the full calendar of cutting-edge parasitology talks and join the community of curious minds
👉 labex-parafrap.fr/en/conferenc...
Explore the full calendar of cutting-edge parasitology talks and join the community of curious minds
👉 labex-parafrap.fr/en/conferenc...
Reposted by Philippe Bastin's Lab
If you have any questions about publishing in JCS, the JCS- @focalplane.bsky.social Training Grants or other @biologists.bsky.social initiatives, stop by booth 1232 at #CellBio2025.
journals.biologists.com/jcs/pages/ab...
@drmichaelway.bsky.social @seemagrewal.bsky.social
journals.biologists.com/jcs/pages/ab...
@drmichaelway.bsky.social @seemagrewal.bsky.social
December 8, 2025 at 11:02 AM
If you have any questions about publishing in JCS, the JCS- @focalplane.bsky.social Training Grants or other @biologists.bsky.social initiatives, stop by booth 1232 at #CellBio2025.
journals.biologists.com/jcs/pages/ab...
@drmichaelway.bsky.social @seemagrewal.bsky.social
journals.biologists.com/jcs/pages/ab...
@drmichaelway.bsky.social @seemagrewal.bsky.social
Reposted by Philippe Bastin's Lab
#LivingArchitectures
We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay.
www.musee-orsay.fr/fr/agenda/ev...
Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night.
-> Two shows on the 24th and 25th of January.
We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay.
www.musee-orsay.fr/fr/agenda/ev...
Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night.
-> Two shows on the 24th and 25th of January.
December 5, 2025 at 4:11 PM
#LivingArchitectures
We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay.
www.musee-orsay.fr/fr/agenda/ev...
Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night.
-> Two shows on the 24th and 25th of January.
We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay.
www.musee-orsay.fr/fr/agenda/ev...
Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night.
-> Two shows on the 24th and 25th of January.
Reposted by Philippe Bastin's Lab
Dive into global health! Enroll in our MOOC on Neglected Tropical Diseases. Learn about NTDs, control strategies, and more. Join the fight against these ancient diseases! 🌍
👉 Enroll now: www.fun-mooc.fr/en/courses/n...
👉 Enroll now: www.fun-mooc.fr/en/courses/n...
Neglected Tropical Diseases
Unlock the secrets of Neglected Tropical Diseases (NTDs) : Discover these diseases, embrace paradigm shifts in elimination programs and explore groundbreaking research opportunities.
www.fun-mooc.fr
November 28, 2025 at 3:21 PM
Dive into global health! Enroll in our MOOC on Neglected Tropical Diseases. Learn about NTDs, control strategies, and more. Join the fight against these ancient diseases! 🌍
👉 Enroll now: www.fun-mooc.fr/en/courses/n...
👉 Enroll now: www.fun-mooc.fr/en/courses/n...
The exceptional Julius Lukes gave a great talk @pasteur.fr today making sense of non-sense #parasites!
November 27, 2025 at 1:02 PM
The exceptional Julius Lukes gave a great talk @pasteur.fr today making sense of non-sense #parasites!
Great time yesterday visiting @biozentrum.unibas.ch many thanks to Alexey Baldin for invitation & organisation, to all lab members of @cellarchlab.com for the cilia debates and of the Spang lab for trafficking and... aging discussions! Impressive building... and nice lights at the train station 😍
November 21, 2025 at 3:01 PM
Great time yesterday visiting @biozentrum.unibas.ch many thanks to Alexey Baldin for invitation & organisation, to all lab members of @cellarchlab.com for the cilia debates and of the Spang lab for trafficking and... aging discussions! Impressive building... and nice lights at the train station 😍
Reposted by Philippe Bastin's Lab
Thrilled to share "in situ APEX activation" (iAPEX), a proximity labeling technology for subcellular #proteomics applied to primary #cilia. iAPEX uses an enzymatic cascade, in which a D-amino acid oxidase locally produces H2O2 to activate ascorbate peroxidase.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An enzymatic cascade enables sensitive and specific proximity labeling proteomics in challenging biological systems - Nature Communications
Proximity labeling allows proteomic mapping of subcellular structures. Here, Sroka et al. develop in situ APEX activation (iAPEX) to overcome limitations of labeling specificity and H2O2 toxicity, app...
www.nature.com
November 14, 2025 at 8:07 PM
Thrilled to share "in situ APEX activation" (iAPEX), a proximity labeling technology for subcellular #proteomics applied to primary #cilia. iAPEX uses an enzymatic cascade, in which a D-amino acid oxidase locally produces H2O2 to activate ascorbate peroxidase.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Exciting project!
Hello mosquito 🦟 and microbiota 🧫 🦠 aficionados, we are looking for a postdoc to join our team (Saleh's lab @salehlabparis.bsky.social at Institut Pasteur @pasteur.fr ) to investigate the interplay between the mosquito, its microbiota, and arboviruses. More information here 👇
November 7, 2025 at 11:10 AM
Exciting project!
Reposted by Philippe Bastin's Lab
Our special issue on ‘Cilia and Flagella’ is now out! Huge thanks to all (authors + reviewers) who contributed, and to our wonderful Guest Editors (@cilialab.bsky.social + @lottepedersen.bsky.social) for pulling it together.
Happy reading!
#cilia #flagella
journals.biologists.com/jcs/issue/13...
Happy reading!
#cilia #flagella
journals.biologists.com/jcs/issue/13...
Volume 138 Issue 20 | Journal of Cell Science | The Company of Biologists
Journal of Cell Science publishes cutting-edge science encompassing all aspects of cell biology. It is published by The Company of Biologists, a not-for-profit organisation.
journals.biologists.com
November 3, 2025 at 5:32 PM
Our special issue on ‘Cilia and Flagella’ is now out! Huge thanks to all (authors + reviewers) who contributed, and to our wonderful Guest Editors (@cilialab.bsky.social + @lottepedersen.bsky.social) for pulling it together.
Happy reading!
#cilia #flagella
journals.biologists.com/jcs/issue/13...
Happy reading!
#cilia #flagella
journals.biologists.com/jcs/issue/13...
A full house for the brilliant talk of Jean Popovici (Institut Pasteur du Cambodge) @pasteur.fr bridging #parasitology and #virology #malaria #plasmodium #Pasteur2030
November 4, 2025 at 7:43 AM
A full house for the brilliant talk of Jean Popovici (Institut Pasteur du Cambodge) @pasteur.fr bridging #parasitology and #virology #malaria #plasmodium #Pasteur2030
Reposted by Philippe Bastin's Lab
Miao Gui and I wrote a Review for the @jcellsci.bsky.social special issue “Cilia and Flagella: From Basic Biology to Disease”. It provides a comprehensive and up-to-date overview of MIP structure, function, and the latest tools used to study them, crafted to serve both newcomers and experts.
a man stands in front of a white board with the words keep that in mind written on it
ALT: a man stands in front of a white board with the words keep that in mind written on it
media.tenor.com
November 3, 2025 at 5:19 AM
Miao Gui and I wrote a Review for the @jcellsci.bsky.social special issue “Cilia and Flagella: From Basic Biology to Disease”. It provides a comprehensive and up-to-date overview of MIP structure, function, and the latest tools used to study them, crafted to serve both newcomers and experts.
Reposted by Philippe Bastin's Lab
📣 Here it is — our overview on ciliary proteomics! Great discussions and writing with @mick-lab.bsky.social and Ronald Roepman 🙏🙏
Hope we didn’t miss anything important - apologies if we did!
#cilia #ciliopathies #proteomics
@theracilproject.bsky.social @for5547.bsky.social
tinyurl.com/yc8ztn5v
Hope we didn’t miss anything important - apologies if we did!
#cilia #ciliopathies #proteomics
@theracilproject.bsky.social @for5547.bsky.social
tinyurl.com/yc8ztn5v
Advances in ciliary proteomics – towards cracking the hidden proteome code of cilia
Summary: This Review explores proteomic strategies for investigating cilia, tracing the evolution from early discoveries to recent advancements enabled by proximity labeling techniques.
journals.biologists.com
November 1, 2025 at 4:34 PM
📣 Here it is — our overview on ciliary proteomics! Great discussions and writing with @mick-lab.bsky.social and Ronald Roepman 🙏🙏
Hope we didn’t miss anything important - apologies if we did!
#cilia #ciliopathies #proteomics
@theracilproject.bsky.social @for5547.bsky.social
tinyurl.com/yc8ztn5v
Hope we didn’t miss anything important - apologies if we did!
#cilia #ciliopathies #proteomics
@theracilproject.bsky.social @for5547.bsky.social
tinyurl.com/yc8ztn5v
Reposted by Philippe Bastin's Lab
One of the ‘Cell Scientists to Watch’ from our #JCSciliaSI is Girish Ram Mali @dyneinassembly.bsky.social @dunnschool.bsky.social. In this interview we learn about Girish’s career path, scientific mentorship, and how science is a human endeavour.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
October 30, 2025 at 4:36 PM
One of the ‘Cell Scientists to Watch’ from our #JCSciliaSI is Girish Ram Mali @dyneinassembly.bsky.social @dunnschool.bsky.social. In this interview we learn about Girish’s career path, scientific mentorship, and how science is a human endeavour.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Daniel's interview!
Read more about this research in our ‘First person’ interview with Daniel Abbühl: journals.biologists.com/jcs/article/...
#JCSciliaSI
#JCSciliaSI
October 29, 2025 at 12:21 PM
Daniel's interview!
Great issue! Bonus: includes Daniel's work on incorporation of tagged tubulin in flagella!
October 28, 2025 at 8:55 AM
Great issue! Bonus: includes Daniel's work on incorporation of tagged tubulin in flagella!
Reposted by Philippe Bastin's Lab
Multiple so called "quality control checks" by the journal almost killed us. - But now it is out!
A novel mito. protein import factor is only essential in T. brucei without kDNA. – Check it out.
Congrats, to the first authors Corinne and Salome and to all our coauthors.
doi.org/10.1111/febs...
A novel mito. protein import factor is only essential in T. brucei without kDNA. – Check it out.
Congrats, to the first authors Corinne and Salome and to all our coauthors.
doi.org/10.1111/febs...
FEBS Press
Protein import into mitochondria relies on TIM complexes and the membrane potential. Trypanosoma brucei has a unique TIM complex, and the role of one subunit, TbTim20, has remained unclear. Here, we ...
doi.org
October 23, 2025 at 6:27 PM
Multiple so called "quality control checks" by the journal almost killed us. - But now it is out!
A novel mito. protein import factor is only essential in T. brucei without kDNA. – Check it out.
Congrats, to the first authors Corinne and Salome and to all our coauthors.
doi.org/10.1111/febs...
A novel mito. protein import factor is only essential in T. brucei without kDNA. – Check it out.
Congrats, to the first authors Corinne and Salome and to all our coauthors.
doi.org/10.1111/febs...
Reposted by Philippe Bastin's Lab
#holobiont parasite: from descriptive studies towards experimental and clinical tangible evidence that parasites are not alone and that it matters!
Upon virus discovery, we showed an association between fluke-borne virus specific IgG titer and avidity and disease severity.
doi.org/10.1101/2025...
Upon virus discovery, we showed an association between fluke-borne virus specific IgG titer and avidity and disease severity.
doi.org/10.1101/2025...
October 23, 2025 at 4:17 AM
#holobiont parasite: from descriptive studies towards experimental and clinical tangible evidence that parasites are not alone and that it matters!
Upon virus discovery, we showed an association between fluke-borne virus specific IgG titer and avidity and disease severity.
doi.org/10.1101/2025...
Upon virus discovery, we showed an association between fluke-borne virus specific IgG titer and avidity and disease severity.
doi.org/10.1101/2025...
Reposted by Philippe Bastin's Lab
🎆 Join us for an unmissable finale to 2025! 🎆 We're thrilled to bring our #cilia & #centrosome community together 25/11/2025 15:00-17:45 GMT! Our 53rd @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social e-symposium schedule is live: www.eventbrite.co.uk/e/bscb-genso... /1
October 21, 2025 at 6:11 PM
🎆 Join us for an unmissable finale to 2025! 🎆 We're thrilled to bring our #cilia & #centrosome community together 25/11/2025 15:00-17:45 GMT! Our 53rd @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social e-symposium schedule is live: www.eventbrite.co.uk/e/bscb-genso... /1
Reposted by Philippe Bastin's Lab
Thank you to the organizers of the CFC meeting 2025 in Oberbronn! See you next year in Lyon! @club-cfc.bsky.social
October 15, 2025 at 2:03 PM
Thank you to the organizers of the CFC meeting 2025 in Oberbronn! See you next year in Lyon! @club-cfc.bsky.social