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parafrap.bsky.social
LabEx ParaFrap
@parafrap.bsky.social
320 followers 220 following 370 posts
ParaFrap is a LabEx (Laboratory of Excellence) created by the French Ministry of #Research in 2012, bringing together 25 leading #Parasitology groups in France.
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parafrap.bsky.social
📢 Next Webinar — November 13
Join us for a talk by Antoine CLAESSENS (LPHI, Montpellier) on:

🧬 “MADBIO: Malaria Integrative Analysis to Discover Biomarkers of Infection Outcome”

📅 Date: November 13
🔗 Register here: labex-parafrap.fr/en/conferenc...
November 4, 2025 at 10:27 AM
parafrap.bsky.social
👏 Congratulations to Karinna RUBIO-PEÑA from the Institut Pasteur (Lucy Glover’s team) for today’s great webinar: “The VEXing question of VSG regulation in the tsetse fly.” 🪰

🗓️ Next webinar: Nov 13 by Antoine CLAESSENS (LPHI, Montpellier)

🔗 Register here: labex-parafrap.fr/en/conferenc...
October 16, 2025 at 1:57 PM
parafrap.bsky.social
The #EMBOWorkshop : Host–parasite relationship has come to a close! Thank you to all speakers, participants, and organizers for four inspiring days of science, discussion, and human connection. Until next time! 🧫✨
October 8, 2025 at 11:32 AM
parafrap.bsky.social
The second poster session is underway at the #EMBOWorkshop : Host–parasite relationship — and the enthusiasm is still as strong as ever! 🔬🧫
October 7, 2025 at 5:38 PM
parafrap.bsky.social
Closing lecture by Manoj Duraisingh for the #EMBOWORKSHOP x @parafrap.bsky.social 🎬
October 7, 2025 at 3:43 PM
parafrap.bsky.social
🧬 Great energy at the first poster session of the #EMBOWorkshop Host–Parasite Relationships!

Fantastic discussions, new ideas, and inspiring exchanges around cutting-edge parasitology research.

Science thrives through sharing!
October 7, 2025 at 6:21 AM
parafrap.bsky.social
The deadline of @embo.org EMBO workshop "Host-Parasite Relationship: From Mechanisms to Control Strategies" Oct. 5-8 (Les Embiez, France), organized by ParaFrap @parafrap.bsky.social, is extended to July 22.
Don't miss out — only a few places remaining! meetings.embo.org/event/25-hos...
July 18, 2025 at 7:54 AM
parafrap.bsky.social
💼 PostDoc position (2 years) on Trypanosoma brucei | Bordeaux, France | Lab MFP with Dr. Frédéric Bringaud @univbordeaux.bsky.social @cnrsaquitaine.bsky.social

🔬 Glycerol and differentiation in Trypanosoma brucei

🗓️ Deadline: September 15.
Start: by November 2025

labex-parafrap.fr/fr/emplois/4...
June 10, 2025 at 9:15 AM
parafrap.bsky.social
📣 Next ParaFrap Webinar: Elisabeth Davioud-Charvet @unistra.fr @cnrs-alsace.bsky.social : "Design of improved plasmodione analogs, chemical tools, and prodrugs to generate oral antimalarial drug candidates for total cure"

🗓️ June 12, 3pm CEST

🎟️ bit.ly/ParaFrapWeb
June 5, 2025 at 12:48 PM
parafrap.bsky.social
Reminder : Today, ParaFrap webinar at 15:00 CEST. @parafrap.bsky.social #leishmania #parasite
parafrap.bsky.social LabEx ParaFrap @parafrap.bsky.social · May 14
📣 Next ParaFrap Webinar: Paul JENKINS (Team Gerald Spaeth) @pasteur.fr: "Determinants for visceral leishmaniasis progression: lessons from hamster and mouse models" @parafrap.bsky.social

Chairperson: Maryse Lebrun @lebrunlab.bsky.social

🗓️ May 15, 3pm CEST

🎟️ bit.ly/ParaFrapWeb
May 15, 2025 at 10:13 AM
parafrap.bsky.social
📢 Big Announcement: Registration & abstract submission open for EMBO Workshop "Host-Parasite Relationship: From Mechanisms to Control Strategies" organized by ParaFrap @parafrap.bsky.social @embo.org

🗓️ 5-8 Oct 2025 - Les Embiez Island-France

🔚Deadline: 15 Jul 2025 meetings.embo.org/event/25-hos...
May 14, 2025 at 7:37 AM
parafrap.bsky.social
📣 Next ParaFrap Webinar: Paul JENKINS (Team Gerald Spaeth) @pasteur.fr: "Determinants for visceral leishmaniasis progression: lessons from hamster and mouse models" @parafrap.bsky.social

Chairperson: Maryse Lebrun @lebrunlab.bsky.social

🗓️ May 15, 3pm CEST

🎟️ bit.ly/ParaFrapWeb
May 14, 2025 at 7:22 AM
parafrap.bsky.social
An ISWI-related chromatin remodeller regulates stage-specific gene expression in #Toxoplasma gondii. By Belen Pachano (ParaFrap PhD student) et al., team @hakimi.bsky.social. In @natmicrobiol.nature.com www.nature.com/articles/s41...
An ISWI-related chromatin remodeller regulates stage-specific gene expression in Toxoplasma gondii - Nature Microbiology
Toxoplasma gondii evolved two ISWI remodellers, TgSNF2h and TgSNF2L. TgSNF2h forms a complex that insulates active genes, regulates MORC-driven sexual commitment and ensures precise gene expression, s...
www.nature.com
April 22, 2025 at 2:39 PM
Reposted by LabEx ParaFrap
hakimi.bsky.social
A humorous reflection on the first article from my stellar PhD student, Belen Pachano.

communities.springernature.com/posts/open-s...
Open Sesame: The Protein Behind Parasite Stage Switching
communities.springernature.com
April 11, 2025 at 2:59 PM
Reposted by LabEx ParaFrap
freddyfrischknecht.bsky.social
Live from Tübingen: the one and only Artur Scherf illuminating #Plasmodium var gene expression using his flower model of the infected red cell.
April 3, 2025 at 8:42 AM
parafrap.bsky.social
📣 Next ParaFrap Webinar: Catherine Lavazec @lavazeclab.bsky.social: "Deciphering the interactions between malaria parasites and erythroblasts" @parafrap.bsky.social @inserm.fr @institutcochin.bsky.social
Chairperson: Artur Scherf

🗓️ April 10, 3pm CEST

🎟️ bit.ly/ParaFrapWeb
April 1, 2025 at 7:57 AM
parafrap.bsky.social
💼 Associate Professor / Toxoplasma / Bordeaux-France

🎓 Teaching: animal biology, metazoan diversity & phylogeny (Bachelor 1,2,3)

🔬 Research: Apicomplexa parasites, focusing on Toxoplasma gondii. @ MFP Lab (UMR5234) @univbordeaux.bsky.social .

🗓️ Deadline: April 4

labex-parafrap.fr/en/job-offer...
Associate professor l Toxoplama l Bordeaux, France
    Associate Professor : Animal Biology and Parasitology – Host-Pathogen Interactions, Bordeaux, France  Teaching Profile ...
labex-parafrap.fr
March 11, 2025 at 9:42 AM
parafrap.bsky.social
📣Next ParaFrap Webinar: Mauld LAMARQUE (Team Maryse Lebrun) @umontpellier.bsky.social : "Pleiotropic role of the malaria parasite PP1 phosphatase during P. falciparum life cycle" @parafrap.bsky.social
Chairperson: Maryse Lebrun @lebrunlab.bsky.social

🗓️ March 13, 3pm CET

🎟️ bit.ly/ParaFrapWeb
March 10, 2025 at 9:18 AM
parafrap.bsky.social
New study in @biorxivpreprint.bsky.social : "A novel #Leishmania infantum reference strain for gene editing and the study of visceral leishmaniasis". By Rokhaya Thiam, ParaFrap PhD student (Team Yvon Sterkers) #parasite #science
biorxivpreprint.bsky.social bioRxivpreprint @biorxivpreprint.bsky.social · Feb 20
A novel Leishmania infantum reference strain for gene editing and the study of visceral leishmaniasis https://www.biorxiv.org/content/10.1101/2025.02.18.638795v1
February 26, 2025 at 1:14 PM
parafrap.bsky.social
Dendritic cell phagosomes recruit GRASP55 for export of antigen-loaded MHC molecules: @Cell Reports @cellpress.bsky.social . ParaFrap team involved in this study: Nicolas Blanchard (Infinity Lab, Toulouse) #toxoplasma www.cell.com/cell-reports...
Dendritic cell phagosomes recruit GRASP55 for export of antigen-loaded MHC molecules
Cebrian et al. demonstrate that the Golgi membrane-associated protein GRASP55 is recruited to late phagosomes in BMDCs. This interaction is essential for trafficking peptide-loaded MHC-I and MHC-II mo...
www.cell.com
February 25, 2025 at 3:52 PM
parafrap.bsky.social
📅 Save the Date! The EMBO Workshop "Host-Parasite Relationship: From Mechanisms to Control Strategies" organized by @ParaFrap will take place on October 5-8, 2025, at Les Embiez Island. Stay updated on registration opening —enter your email here: coming-soon.embo.org/w25-83 #Science #Parasite
February 25, 2025 at 3:38 PM
parafrap.bsky.social
📣Today-ParaFrap Webinar: Gretchen DIFFENDALL (Team A.Scherf @pasteur.fr): Metabolomics Identifies a Natural Host Cytoadhesion Inhibitor in Asymptomatic #Malaria Cases
@parafrap.bsky.social
Chairperson: A. CLAESSENS @ant1-claessens.bsky.social

🗓️ February 13, 3pm CET

🎟️ bit.ly/ParaFrapWeb
February 13, 2025 at 8:23 AM
Reposted by LabEx ParaFrap
parafrap.bsky.social
📣 ParaFrap Webinar: Gretchen DIFFENDALL (Team A.Scherf @pasteur.fr): Metabolomics Identifies a Natural Host Cytoadhesion Inhibitor in Asymptomatic #Malaria Cases
@parafrap.bsky.social
Chairperson: Antoine CLAESSENS @ant1-claessens.bsky.social

🗓️ Thursday, February 13, 3pm CET

🎟️ bit.ly/ParaFrapWeb
February 4, 2025 at 3:07 PM
parafrap.bsky.social
Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in #Plasmodium berghei. In Scientific Reports @SciReports ParaFrap Team: Olivier Silvie rdcu.be/d9iFF
Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei
Scientific Reports - Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei
rdcu.be
February 10, 2025 at 10:54 AM
parafrap.bsky.social
Development of tolerance to bedaquiline by overexpression of trypanosomal acetate: succinate CoA transferase in #Mycobacterium smegmatis. In Communications Biology
@commsbio.bsky.social . ParaFrap team involved in this study: Frédéric Bringaud. www.nature.com/articles/s42...
Development of tolerance to bedaquiline by overexpression of trypanosomal acetate: succinate CoA transferase in Mycobacterium smegmatis - Communications Biology
The ATP synthase inhibitor bedaquiline (BDQ) inhibits mycobacterial growth by depleting ATP, with gained tolerance to low BDQ concentrations through metabolic transplantation of trypanosomal SLPHOS pa...
www.nature.com
February 10, 2025 at 10:37 AM