André Schneider, University of Bern
@schneian.bsky.social
Biochemist interested in mitochondria, trypanosomes and science in general
Pinned
A piece of science history about RNA, oxygen, and mice cages
There is nothing is more important in an experiment than the proper controls. But what should you do if your experimental control fails? - read my short essay on failed experimental controls.
www.embopress.org/doi/full/10....?
There is nothing is more important in an experiment than the proper controls. But what should you do if your experimental control fails? - read my short essay on failed experimental controls.
www.embopress.org/doi/full/10....?
Reposted by André Schneider, University of Bern
💊 Resistance against antibiotics is a severe threat - also in 🇨🇭
The Forum Phagentherapie discusses with experts and the public about solutions.
👉 Register for our phage forum on Jan 31 in Basel: lnkd.in/e-im3e-g
‼️ Voices from society and patients are vital to develop viable approaches.
The Forum Phagentherapie discusses with experts and the public about solutions.
👉 Register for our phage forum on Jan 31 in Basel: lnkd.in/e-im3e-g
‼️ Voices from society and patients are vital to develop viable approaches.
January 4, 2026 at 2:04 PM
💊 Resistance against antibiotics is a severe threat - also in 🇨🇭
The Forum Phagentherapie discusses with experts and the public about solutions.
👉 Register for our phage forum on Jan 31 in Basel: lnkd.in/e-im3e-g
‼️ Voices from society and patients are vital to develop viable approaches.
The Forum Phagentherapie discusses with experts and the public about solutions.
👉 Register for our phage forum on Jan 31 in Basel: lnkd.in/e-im3e-g
‼️ Voices from society and patients are vital to develop viable approaches.
Reposted by André Schneider, University of Bern
The winner of ✨ #planetaryScience image of 2025 ✨ is
✨Uranus as seen by JWST✨
Taken on: October 6, 2025
Credit: NASA/ @esa.int /CSA/ @stsci.edu / @andrealuck.bsky.social
Full resolution: www.flickr.com/photos/19227...
🧪⚛️
✨Uranus as seen by JWST✨
Taken on: October 6, 2025
Credit: NASA/ @esa.int /CSA/ @stsci.edu / @andrealuck.bsky.social
Full resolution: www.flickr.com/photos/19227...
🧪⚛️
December 30, 2025 at 5:37 PM
The winner of ✨ #planetaryScience image of 2025 ✨ is
✨Uranus as seen by JWST✨
Taken on: October 6, 2025
Credit: NASA/ @esa.int /CSA/ @stsci.edu / @andrealuck.bsky.social
Full resolution: www.flickr.com/photos/19227...
🧪⚛️
✨Uranus as seen by JWST✨
Taken on: October 6, 2025
Credit: NASA/ @esa.int /CSA/ @stsci.edu / @andrealuck.bsky.social
Full resolution: www.flickr.com/photos/19227...
🧪⚛️
David got company!
December 18, 2025 at 3:14 PM
David got company!
Reposted by André Schneider, University of Bern
Well, this is an utter disaster for science.
This gutting of peer review is very likely driven by Project 2025/OMB/Vought, very likely is about funding junk science, and very likely is coming for #NIH and biomedical research next.
🧪
This gutting of peer review is very likely driven by Project 2025/OMB/Vought, very likely is about funding junk science, and very likely is coming for #NIH and biomedical research next.
🧪
December 16, 2025 at 4:10 AM
Well, this is an utter disaster for science.
This gutting of peer review is very likely driven by Project 2025/OMB/Vought, very likely is about funding junk science, and very likely is coming for #NIH and biomedical research next.
🧪
This gutting of peer review is very likely driven by Project 2025/OMB/Vought, very likely is about funding junk science, and very likely is coming for #NIH and biomedical research next.
🧪
Reposted by André Schneider, University of Bern
This is actually the trippiest thing I've ever seen that was not deliberately created by M C Fucking Escher. It straight up took me over a minute to make sense of and now I can't go back.
This is the white-and-gold dress on a gram a week of trenbolone.
This is the white-and-gold dress on a gram a week of trenbolone.
Ok, this is nuts. Once you see it you cannot unsee it. Do you see it?
(OP @drgbuckingham.bsky.social )
(OP @drgbuckingham.bsky.social )
December 17, 2025 at 6:52 AM
This is actually the trippiest thing I've ever seen that was not deliberately created by M C Fucking Escher. It straight up took me over a minute to make sense of and now I can't go back.
This is the white-and-gold dress on a gram a week of trenbolone.
This is the white-and-gold dress on a gram a week of trenbolone.
In the early 1980ies the labs of Cordingley, Boothroyd and Borst
discovered that the LSU rRNA of T. brucei is processed into 6 fragment. Now more than 30 years later Simona Amodeo at al. found the factors that mediate these trypanosomatid-specific processing events. academic.oup.com/nar/article/...
discovered that the LSU rRNA of T. brucei is processed into 6 fragment. Now more than 30 years later Simona Amodeo at al. found the factors that mediate these trypanosomatid-specific processing events. academic.oup.com/nar/article/...
A trypanosome-specific complex mediates late-stage processing of cytosolic LSU rRNA
Abstract. Unlike most eukaryotes, Trypanosoma brucei processes its cytosolic large subunit (LSU) RNA into six fragments. The factors responsible for these
academic.oup.com
December 15, 2025 at 12:30 PM
In the early 1980ies the labs of Cordingley, Boothroyd and Borst
discovered that the LSU rRNA of T. brucei is processed into 6 fragment. Now more than 30 years later Simona Amodeo at al. found the factors that mediate these trypanosomatid-specific processing events. academic.oup.com/nar/article/...
discovered that the LSU rRNA of T. brucei is processed into 6 fragment. Now more than 30 years later Simona Amodeo at al. found the factors that mediate these trypanosomatid-specific processing events. academic.oup.com/nar/article/...
Reposted by André Schneider, University of Bern
Have you ever wondered what you would find if you could keep your eyes on a bee for more than a few meters? Us, too!
preprint (with videos!) + thread 🧵
Precise, individualized foraging flights in honey #bees 🐝 revealed by multicopter drone-based tracking
www.biorxiv.org/content/10.6...
1/9
preprint (with videos!) + thread 🧵
Precise, individualized foraging flights in honey #bees 🐝 revealed by multicopter drone-based tracking
www.biorxiv.org/content/10.6...
1/9
December 6, 2025 at 2:01 PM
Have you ever wondered what you would find if you could keep your eyes on a bee for more than a few meters? Us, too!
preprint (with videos!) + thread 🧵
Precise, individualized foraging flights in honey #bees 🐝 revealed by multicopter drone-based tracking
www.biorxiv.org/content/10.6...
1/9
preprint (with videos!) + thread 🧵
Precise, individualized foraging flights in honey #bees 🐝 revealed by multicopter drone-based tracking
www.biorxiv.org/content/10.6...
1/9
Reposted by André Schneider, University of Bern
I wanted to take the bus but it was stationary
December 7, 2025 at 4:05 PM
I wanted to take the bus but it was stationary
Reposted by André Schneider, University of Bern
How does a caterpillar completely dissolve inside its chrysalis, before reconstructing itself in the shape of a butterfly?
“Metamorphosis is wild,” marvels historian Oren Harman in his beautiful new book, which I reviewed for this week's @nature.com
www.nature.com/articles/d41...
“Metamorphosis is wild,” marvels historian Oren Harman in his beautiful new book, which I reviewed for this week's @nature.com
www.nature.com/articles/d41...
December 2, 2025 at 3:55 PM
How does a caterpillar completely dissolve inside its chrysalis, before reconstructing itself in the shape of a butterfly?
“Metamorphosis is wild,” marvels historian Oren Harman in his beautiful new book, which I reviewed for this week's @nature.com
www.nature.com/articles/d41...
“Metamorphosis is wild,” marvels historian Oren Harman in his beautiful new book, which I reviewed for this week's @nature.com
www.nature.com/articles/d41...
Reposted by André Schneider, University of Bern
📢Postdoc position available!🧪🧫🧬
Our group is seeking a motivated researcher to investigate the molecular mechanisms driving host–endosymbiont interactions.
Full details & application: karriere.hhu.de//index.php?a....
Please help us get the word out!
Our group is seeking a motivated researcher to investigate the molecular mechanisms driving host–endosymbiont interactions.
Full details & application: karriere.hhu.de//index.php?a....
Please help us get the word out!
Postdoc (m/f/d) in Endosymbiosis Research
karriere.hhu.de
November 25, 2025 at 11:21 AM
📢Postdoc position available!🧪🧫🧬
Our group is seeking a motivated researcher to investigate the molecular mechanisms driving host–endosymbiont interactions.
Full details & application: karriere.hhu.de//index.php?a....
Please help us get the word out!
Our group is seeking a motivated researcher to investigate the molecular mechanisms driving host–endosymbiont interactions.
Full details & application: karriere.hhu.de//index.php?a....
Please help us get the word out!
Reposted by André Schneider, University of Bern
What is the most profitable industry in the world, this side of the law? Not oil, not IT, not pharma.
It's *scientific publishing*.
We call this the Drain of Scientific Publishing.
Paper: arxiv.org/abs/2511.04820
Background: doi.org/10.1162/qss_...
Thread @markhanson.fediscience.org.ap.brid.gy 👇
It's *scientific publishing*.
We call this the Drain of Scientific Publishing.
Paper: arxiv.org/abs/2511.04820
Background: doi.org/10.1162/qss_...
Thread @markhanson.fediscience.org.ap.brid.gy 👇
November 12, 2025 at 10:31 AM
What is the most profitable industry in the world, this side of the law? Not oil, not IT, not pharma.
It's *scientific publishing*.
We call this the Drain of Scientific Publishing.
Paper: arxiv.org/abs/2511.04820
Background: doi.org/10.1162/qss_...
Thread @markhanson.fediscience.org.ap.brid.gy 👇
It's *scientific publishing*.
We call this the Drain of Scientific Publishing.
Paper: arxiv.org/abs/2511.04820
Background: doi.org/10.1162/qss_...
Thread @markhanson.fediscience.org.ap.brid.gy 👇
Reposted by André Schneider, University of Bern
Schrödinger: Excuse me, miss, can I borrow that box for a science experiment?
Pandora: Sure, be my guest.
Pandora: Sure, be my guest.
November 9, 2025 at 5:38 AM
Schrödinger: Excuse me, miss, can I borrow that box for a science experiment?
Pandora: Sure, be my guest.
Pandora: Sure, be my guest.
Reposted by André Schneider, University of Bern
- Picture by Raymond Gosling and Rosalind Franklin, King's College
- DNA by Rudolf Signer, University of Bern
- DNA by Rudolf Signer, University of Bern
March 7, 2025 at 4:36 PM
- Picture by Raymond Gosling and Rosalind Franklin, King's College
- DNA by Rudolf Signer, University of Bern
- DNA by Rudolf Signer, University of Bern
Reposted by André Schneider, University of Bern
Holy smokes!!!!
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
November 8, 2025 at 12:16 AM
Holy smokes!!!!
Reposted by André Schneider, University of Bern
Here we are! To celebrate our arrival, here is a #trypanosome expanded ~13 times & stained for tubulin, individual cortical #microtubules can be recognised, what was only achievable by EM before. Images: Christine Girard-Blanc & Thierry Blisnick. Many thanks to @centriolelab.bsky.social for training
November 26, 2024 at 9:12 PM
Here we are! To celebrate our arrival, here is a #trypanosome expanded ~13 times & stained for tubulin, individual cortical #microtubules can be recognised, what was only achievable by EM before. Images: Christine Girard-Blanc & Thierry Blisnick. Many thanks to @centriolelab.bsky.social for training
Reposted by André Schneider, University of Bern
Paper by the Schneider lab( @schneian.bsky.social ) & collaborators w/co-first authors Corinne von Känel & Salome Aeschlimann "TbTim20 facilitates protein import at a low membrane potential in trypanosomes lacking the mitochondrial genome" @febsj.bsky.social nccr-rna-and-disease.ch/news/article...
October 27, 2025 at 8:02 AM
Paper by the Schneider lab( @schneian.bsky.social ) & collaborators w/co-first authors Corinne von Känel & Salome Aeschlimann "TbTim20 facilitates protein import at a low membrane potential in trypanosomes lacking the mitochondrial genome" @febsj.bsky.social nccr-rna-and-disease.ch/news/article...
Multiple so called "quality control checks" by the journal almost killed us. - But now it is out!
A novel mito. protein import factor is only essential in T. brucei without kDNA. – Check it out.
Congrats, to the first authors Corinne and Salome and to all our coauthors.
doi.org/10.1111/febs...
A novel mito. protein import factor is only essential in T. brucei without kDNA. – Check it out.
Congrats, to the first authors Corinne and Salome and to all our coauthors.
doi.org/10.1111/febs...
FEBS Press
Protein import into mitochondria relies on TIM complexes and the membrane potential. Trypanosoma brucei has a unique TIM complex, and the role of one subunit, TbTim20, has remained unclear. Here, we ...
doi.org
October 23, 2025 at 6:27 PM
Multiple so called "quality control checks" by the journal almost killed us. - But now it is out!
A novel mito. protein import factor is only essential in T. brucei without kDNA. – Check it out.
Congrats, to the first authors Corinne and Salome and to all our coauthors.
doi.org/10.1111/febs...
A novel mito. protein import factor is only essential in T. brucei without kDNA. – Check it out.
Congrats, to the first authors Corinne and Salome and to all our coauthors.
doi.org/10.1111/febs...
Reposted by André Schneider, University of Bern
The flagellar pocket collar (FPC) is a cytoskeletal structure essential for nutrient uptake & immune evasion in #Trypanosome. @mbonhivers.bsky.social &co use U-ExM to provide novel insights into FPC biogenesis, and reveal 2 unknown cytoskeletal structures @plosbiology.org 🧪 plos.io/4n3bWi6
October 13, 2025 at 12:55 PM
The flagellar pocket collar (FPC) is a cytoskeletal structure essential for nutrient uptake & immune evasion in #Trypanosome. @mbonhivers.bsky.social &co use U-ExM to provide novel insights into FPC biogenesis, and reveal 2 unknown cytoskeletal structures @plosbiology.org 🧪 plos.io/4n3bWi6
Reposted by André Schneider, University of Bern
Video: a Japanese scientist was attacked by flies while giving the acceptance speech for his Ig Nobel Prize-winning research paper that proved painting Zebra-like stripes on cows led to a decrease in biting fly attacks.
September 19, 2025 at 9:58 AM
Video: a Japanese scientist was attacked by flies while giving the acceptance speech for his Ig Nobel Prize-winning research paper that proved painting Zebra-like stripes on cows led to a decrease in biting fly attacks.
...and now something for RNA enthusiasts
@nccr-rna-disease.bsky.social
The function of the vault complex has finally been solved: it is a lampshade.
@nccr-rna-disease.bsky.social
The function of the vault complex has finally been solved: it is a lampshade.
September 24, 2025 at 12:21 PM
...and now something for RNA enthusiasts
@nccr-rna-disease.bsky.social
The function of the vault complex has finally been solved: it is a lampshade.
@nccr-rna-disease.bsky.social
The function of the vault complex has finally been solved: it is a lampshade.
Another case of convergent evolution?
September 20, 2025 at 1:07 PM
Another case of convergent evolution?
Convergent Evolution? – Spiral staircase in the “Église Saint-Catherine” in Loix, France
September 20, 2025 at 12:45 PM
Convergent Evolution? – Spiral staircase in the “Église Saint-Catherine” in Loix, France
Reposted by André Schneider, University of Bern
Congrats to all authors, especially Lim who had an impressive PhD viva last week! TAC is a very interesting structure linking mitochondrial DNA and basal bodies in trypanosomes
September 19, 2025 at 11:22 AM
Congrats to all authors, especially Lim who had an impressive PhD viva last week! TAC is a very interesting structure linking mitochondrial DNA and basal bodies in trypanosomes
The trypanosomal TAC of is required for mitochondrial DNA segregation: Discovery of the novel TAC53 subunit and the tubular arrangement of the TAC filaments
Joint study by the Ochsenreiter and Schneiderlabs.
👏 to 1. Author Lim.
journals.plos.org/plospathogen...
#mitochondria #mtDNA #Trypanosoma
Joint study by the Ochsenreiter and Schneiderlabs.
👏 to 1. Author Lim.
journals.plos.org/plospathogen...
#mitochondria #mtDNA #Trypanosoma
Connecting basal body and mitochondrial DNA: TAC53 and the tubular organization of the tripartite attachment complex
Author summary Trypanosoma brucei, is the causative agent of human African sleeping sickness and nagana in cattle. The eukaryotic parasite relies on the faithful inheritance of its singular mitochondr...
journals.plos.org
September 18, 2025 at 9:49 AM
The trypanosomal TAC of is required for mitochondrial DNA segregation: Discovery of the novel TAC53 subunit and the tubular arrangement of the TAC filaments
Joint study by the Ochsenreiter and Schneiderlabs.
👏 to 1. Author Lim.
journals.plos.org/plospathogen...
#mitochondria #mtDNA #Trypanosoma
Joint study by the Ochsenreiter and Schneiderlabs.
👏 to 1. Author Lim.
journals.plos.org/plospathogen...
#mitochondria #mtDNA #Trypanosoma
Reposted by André Schneider, University of Bern
so happy to have Katie as a colleague !
Nice interview to Katie Peichel @currentbiology.bsky.social
I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.
www.cell.com/current-biol...
I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.
www.cell.com/current-biol...
Catherine Peichel
Interview with Katie Peichel, who studies the evolutionary genetics of sticklebacks
at the University of Bern, Switzerland.
www.cell.com
September 10, 2025 at 3:45 PM
so happy to have Katie as a colleague !