Olivier Pertz
@olivierpertz.bsky.social
Prof at University of Bern
#MAPK #Rho #optogenetics #biosensors #computer_vision
skiing, rock/ice/mountain climbing when I have time
#MAPK #Rho #optogenetics #biosensors #computer_vision
skiing, rock/ice/mountain climbing when I have time
This Wednesday @bgraedel.bsky.social defended his PhD — crowning an extraordinary scientific journey.
He showed how live-cell imaging and computational modeling can reveal and perturb cytoskeletal dynamics at micrometer and second-level scales.
Thanks Benjamin — a wild, inspiring ride! 🚀
He showed how live-cell imaging and computational modeling can reveal and perturb cytoskeletal dynamics at micrometer and second-level scales.
Thanks Benjamin — a wild, inspiring ride! 🚀
November 7, 2025 at 12:15 PM
This Wednesday @bgraedel.bsky.social defended his PhD — crowning an extraordinary scientific journey.
He showed how live-cell imaging and computational modeling can reveal and perturb cytoskeletal dynamics at micrometer and second-level scales.
Thanks Benjamin — a wild, inspiring ride! 🚀
He showed how live-cell imaging and computational modeling can reveal and perturb cytoskeletal dynamics at micrometer and second-level scales.
Thanks Benjamin — a wild, inspiring ride! 🚀
Reposted by Olivier Pertz
Very happy to share our latest work extending iterative immunofluorescence to in toto imaging of early zebrafish embryos (3D-4i), integrated with a 3D-dedicated image analysis pipeline! 🐟🔬📊
Huge kudos to Max Hess for this PhD milestone! 💪
@lucaspelkmans.bsky.social shorturl.at/cO0u7
Let's zoom in!
Huge kudos to Max Hess for this PhD milestone! 💪
@lucaspelkmans.bsky.social shorturl.at/cO0u7
Let's zoom in!
October 29, 2025 at 2:20 PM
Very happy to share our latest work extending iterative immunofluorescence to in toto imaging of early zebrafish embryos (3D-4i), integrated with a 3D-dedicated image analysis pipeline! 🐟🔬📊
Huge kudos to Max Hess for this PhD milestone! 💪
@lucaspelkmans.bsky.social shorturl.at/cO0u7
Let's zoom in!
Huge kudos to Max Hess for this PhD milestone! 💪
@lucaspelkmans.bsky.social shorturl.at/cO0u7
Let's zoom in!
Excited to join the Fusion Conference on Fibroblast Growth Factor Signalling this May in Malta 🇲🇹!
I’ll be discussing how FGF–MAP kinase signaling unfolds at the single-cell level — bridging molecules to cell decisions 🔬✨
#FGF #MAPK #conference www.fusion-conferences.com/conference/195
I’ll be discussing how FGF–MAP kinase signaling unfolds at the single-cell level — bridging molecules to cell decisions 🔬✨
#FGF #MAPK #conference www.fusion-conferences.com/conference/195
Fibroblast Growth Factor Signalling in Development, Health & Disease Conference | Fusion Conferences
Receptor Tyrosine Kinases (RTKs) are cell-surface receptors that, upon ligand binding, regulate cell-to-cell communication during embryonic development and in adult life. Among RTKs, the twenty-two Fi...
www.fusion-conferences.com
October 21, 2025 at 12:20 PM
Excited to join the Fusion Conference on Fibroblast Growth Factor Signalling this May in Malta 🇲🇹!
I’ll be discussing how FGF–MAP kinase signaling unfolds at the single-cell level — bridging molecules to cell decisions 🔬✨
#FGF #MAPK #conference www.fusion-conferences.com/conference/195
I’ll be discussing how FGF–MAP kinase signaling unfolds at the single-cell level — bridging molecules to cell decisions 🔬✨
#FGF #MAPK #conference www.fusion-conferences.com/conference/195
Went to see Yayoi Kusama’s mind-bending art at the Beyeler Foundation in Basel. As a biologist, I tried to enjoy the art… but my brain kept yelling "nuclei!", “organoid!”, and “endocytosis!”. Here are some of my favorite accidental biology sightings. 🧬🎨🧫
October 19, 2025 at 8:11 PM
Went to see Yayoi Kusama’s mind-bending art at the Beyeler Foundation in Basel. As a biologist, I tried to enjoy the art… but my brain kept yelling "nuclei!", “organoid!”, and “endocytosis!”. Here are some of my favorite accidental biology sightings. 🧬🎨🧫
Reposted by Olivier Pertz
Want to get started with smart microscopy? 🧠🔬
Check out our online repository with implementations from labs and industry -- lots of practical tips and links to sample code! smartmicroscopy.github.io/implementati...
More details in the ✨updated preprint!✨
www.biorxiv.org/content/10.1...
Check out our online repository with implementations from labs and industry -- lots of practical tips and links to sample code! smartmicroscopy.github.io/implementati...
More details in the ✨updated preprint!✨
www.biorxiv.org/content/10.1...
October 1, 2025 at 9:43 AM
Want to get started with smart microscopy? 🧠🔬
Check out our online repository with implementations from labs and industry -- lots of practical tips and links to sample code! smartmicroscopy.github.io/implementati...
More details in the ✨updated preprint!✨
www.biorxiv.org/content/10.1...
Check out our online repository with implementations from labs and industry -- lots of practical tips and links to sample code! smartmicroscopy.github.io/implementati...
More details in the ✨updated preprint!✨
www.biorxiv.org/content/10.1...
Reposted by Olivier Pertz
Cell and developmental biologists; This is well worth a read: Maik and Roberto synthesize work over decades to propose a provocative model of who mesenchymal cells migrate and shape tissues 🧪 Go for the cool Figures, stay for the deep insights
New perspective in @jcb.org by @maikbischoff.bsky.social & @mayorlab.bsky.social about how mesenchymal cells use contact-dependent rules to generate swarm-like behaviors, patterns & organ forms. rupress.org/jcb/article/...
#CellBio #CellMigration #Morphogenesis #Development #Science
#CellBio #CellMigration #Morphogenesis #Development #Science
September 23, 2025 at 11:04 PM
Cell and developmental biologists; This is well worth a read: Maik and Roberto synthesize work over decades to propose a provocative model of who mesenchymal cells migrate and shape tissues 🧪 Go for the cool Figures, stay for the deep insights
Reposted by Olivier Pertz
Its raining #Ichthyos ... Hallelujah!
#Lattice #LightSheet #Ichthyosporeans #Creolimax #Cellularization #ProtistsOnSky
#Lattice #LightSheet #Ichthyosporeans #Creolimax #Cellularization #ProtistsOnSky
September 15, 2025 at 7:52 AM
Its raining #Ichthyos ... Hallelujah!
#Lattice #LightSheet #Ichthyosporeans #Creolimax #Cellularization #ProtistsOnSky
#Lattice #LightSheet #Ichthyosporeans #Creolimax #Cellularization #ProtistsOnSky
so happy to have Katie as a colleague !
Nice interview to Katie Peichel @currentbiology.bsky.social
I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.
www.cell.com/current-biol...
I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.
www.cell.com/current-biol...
Catherine Peichel
Interview with Katie Peichel, who studies the evolutionary genetics of sticklebacks
at the University of Bern, Switzerland.
www.cell.com
September 10, 2025 at 3:45 PM
so happy to have Katie as a colleague !
Reposted by Olivier Pertz
Nice interview to Katie Peichel @currentbiology.bsky.social
I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.
www.cell.com/current-biol...
I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.
www.cell.com/current-biol...
Catherine Peichel
Interview with Katie Peichel, who studies the evolutionary genetics of sticklebacks
at the University of Bern, Switzerland.
www.cell.com
September 9, 2025 at 2:36 PM
Nice interview to Katie Peichel @currentbiology.bsky.social
I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.
www.cell.com/current-biol...
I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.
www.cell.com/current-biol...
looks like an ingenious combination of technologies to study out of equilibrium developmental processes ... Congrats !
Preprint alert!
We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength.
doi.org/10.1101/2025...
We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength.
doi.org/10.1101/2025...
September 9, 2025 at 7:20 PM
looks like an ingenious combination of technologies to study out of equilibrium developmental processes ... Congrats !
⚡️ Don’t forget that we’re looking for a Tenure-track Assistant Professor in Quantitative Cell Biology @ UniBern!
🔬 Bridge experiments + theory
📈 Tackle processes across scales
💡 Join our vibrant research community
Deadline Oct 17 👉 shorturl.at/1Y1WP
🔬 Bridge experiments + theory
📈 Tackle processes across scales
💡 Join our vibrant research community
Deadline Oct 17 👉 shorturl.at/1Y1WP
Assistant Professor with tenure-track for Quantitative Cell Biology (80-100%) - Bern, Switzerland job with University of Bern, Institute of Cell Biology | 12840798
Assistant Professor with tenure-track for Quantitative Cell Biology (80-100%) at the University of Bern, Switzerland.
shorturl.at
September 9, 2025 at 3:32 PM
⚡️ Don’t forget that we’re looking for a Tenure-track Assistant Professor in Quantitative Cell Biology @ UniBern!
🔬 Bridge experiments + theory
📈 Tackle processes across scales
💡 Join our vibrant research community
Deadline Oct 17 👉 shorturl.at/1Y1WP
🔬 Bridge experiments + theory
📈 Tackle processes across scales
💡 Join our vibrant research community
Deadline Oct 17 👉 shorturl.at/1Y1WP
Reposted by Olivier Pertz
Summer break prevented me from properly advertising this serie of reviews on the function of cell death during development that I edited. There is still a lot to dig in regarding regulation of apoptosis in vivo ad I hope we managed to illustrate this well
www.sciencedirect.com/special-issu...
www.sciencedirect.com/special-issu...
Seminars in Cell & Developmental Biology | Novel functions of programmed cell death in development: current status and future challenges | ScienceDirect.com by Elsevier
While the core regulators of programmed cell death have been relatively well characterised, our understanding of the regulation and role of programmed cell death in tissue during embryonic development...
www.sciencedirect.com
August 28, 2025 at 10:58 AM
Summer break prevented me from properly advertising this serie of reviews on the function of cell death during development that I edited. There is still a lot to dig in regarding regulation of apoptosis in vivo ad I hope we managed to illustrate this well
www.sciencedirect.com/special-issu...
www.sciencedirect.com/special-issu...
Reposted by Olivier Pertz
2 weeks ago we were some of the first to see 'Cancer Revolution: Science, Innovation & Hope,' the astounding new exhibition from Breakthrough Cancer Research. Read more about this free interactive display & our involvement in the project along w/ @precisiononcire.bsky.social
ucd.ie/sbi/news/new...
ucd.ie/sbi/news/new...
August 27, 2025 at 2:59 PM
2 weeks ago we were some of the first to see 'Cancer Revolution: Science, Innovation & Hope,' the astounding new exhibition from Breakthrough Cancer Research. Read more about this free interactive display & our involvement in the project along w/ @precisiononcire.bsky.social
ucd.ie/sbi/news/new...
ucd.ie/sbi/news/new...
“New paper out 🎉 We built a system to automate optogenetic cell control across scales. For the demo, we made the cells spell my name — because if you can’t use science to feed your ego, what’s the point? 😎🧫✨”
Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out! www.biorxiv.org/content/10.1...
August 22, 2025 at 2:41 PM
“New paper out 🎉 We built a system to automate optogenetic cell control across scales. For the demo, we made the cells spell my name — because if you can’t use science to feed your ego, what’s the point? 😎🧫✨”
Reposted by Olivier Pertz
Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out! www.biorxiv.org/content/10.1...
August 21, 2025 at 8:16 PM
Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out! www.biorxiv.org/content/10.1...
Congrats @lhinderling.bsky.social and team
So many people involved! Special thanks to @hannah-superres.bsky.social, Alfredo Rates, @olivierpertz.bsky.social, @nilsnorlin.bsky.social, Aliaksandr Halavatyi & Rafael Camacho. Link again to the paper: www.biorxiv.org/content/10.1...
August 22, 2025 at 2:38 PM
Congrats @lhinderling.bsky.social and team
Reposted by Olivier Pertz
So many people involved! Special thanks to @hannah-superres.bsky.social, Alfredo Rates, @olivierpertz.bsky.social, @nilsnorlin.bsky.social, Aliaksandr Halavatyi & Rafael Camacho. Link again to the paper: www.biorxiv.org/content/10.1...
August 21, 2025 at 2:22 PM
So many people involved! Special thanks to @hannah-superres.bsky.social, Alfredo Rates, @olivierpertz.bsky.social, @nilsnorlin.bsky.social, Aliaksandr Halavatyi & Rafael Camacho. Link again to the paper: www.biorxiv.org/content/10.1...
Reposted by Olivier Pertz
Not only acquisition settings can be changed, but also perturbation: Popular is automated targeting of photomanipulation:
August 21, 2025 at 2:22 PM
Not only acquisition settings can be changed, but also perturbation: Popular is automated targeting of photomanipulation:
Reposted by Olivier Pertz
For example event-driven acquisition: rare events (here mitoses) are detected in a low-res overview scan, the microscope switches objective to automatically image only the mitotic cells in high-res. 🔎
August 21, 2025 at 2:22 PM
For example event-driven acquisition: rare events (here mitoses) are detected in a low-res overview scan, the microscope switches objective to automatically image only the mitotic cells in high-res. 🔎
Reposted by Olivier Pertz
🔬🧠 Our paper on smart microscopy & the issue of interoperability! www.biorxiv.org/content/10.1... LONG THREAD WARNING: Smart microscopy uses real-time image analysis to automatically guide the acquisition or perturbation of the sample (closed feedback-control loop). Many applications exist:
August 21, 2025 at 2:22 PM
🔬🧠 Our paper on smart microscopy & the issue of interoperability! www.biorxiv.org/content/10.1... LONG THREAD WARNING: Smart microscopy uses real-time image analysis to automatically guide the acquisition or perturbation of the sample (closed feedback-control loop). Many applications exist:
Reposted by Olivier Pertz
In the latest issue of Lab on a Chip:
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology.
#OpenAccess from Olivier Pertz, Lucien Hinderling et al @olivierpertz.bsky.social @lhinderling.bsky.social.
Read now: pubs.rsc.org/en/content/a...
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology.
#OpenAccess from Olivier Pertz, Lucien Hinderling et al @olivierpertz.bsky.social @lhinderling.bsky.social.
Read now: pubs.rsc.org/en/content/a...
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology
The application of traditional microfabrication techniques to biological research is hindered by their reliance on clean rooms, expensive or toxic materials, and slow iteration cycles. We present an a...
pubs.rsc.org
August 6, 2025 at 9:33 AM
In the latest issue of Lab on a Chip:
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology.
#OpenAccess from Olivier Pertz, Lucien Hinderling et al @olivierpertz.bsky.social @lhinderling.bsky.social.
Read now: pubs.rsc.org/en/content/a...
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology.
#OpenAccess from Olivier Pertz, Lucien Hinderling et al @olivierpertz.bsky.social @lhinderling.bsky.social.
Read now: pubs.rsc.org/en/content/a...
Reposted by Olivier Pertz
Introducing five concepts from dynamical systems to decode developmental regulatory mechanisms, have a read! @perez-carrasco.bsky.social @roederlab.bsky.social @mpipz.bsky.social This effort started in a morphogenesis meeting @kitp-ucsb.bsky.social in 2023. journals.biologists.com/dev/article/...
August 4, 2025 at 6:42 AM
Introducing five concepts from dynamical systems to decode developmental regulatory mechanisms, have a read! @perez-carrasco.bsky.social @roederlab.bsky.social @mpipz.bsky.social This effort started in a morphogenesis meeting @kitp-ucsb.bsky.social in 2023. journals.biologists.com/dev/article/...
Reposted by Olivier Pertz
@lwellberg.bsky.social @josjonkers.bsky.social @olivierpertz.bsky.social @juliosaezrod.bsky.social
please share with your followers - thank you!
please share with your followers - thank you!
August 4, 2025 at 10:51 AM
@lwellberg.bsky.social @josjonkers.bsky.social @olivierpertz.bsky.social @juliosaezrod.bsky.social
please share with your followers - thank you!
please share with your followers - thank you!
Thanks for having me !
Happy to chair a session on cell and pathway engineering at ICSB2025.com featuring e.g. an inspiring talk by @olivierpertz.bsky.social on pathway dynamics, cell fates and optical tools. Contributed talk deadline is today, Sept 1st for poster abstracts. Hope to see you in Dublin in October! #ICSB2025
August 1, 2025 at 3:12 PM
Thanks for having me !
Reposted by Olivier Pertz
first data from the new LLSM in PertzLab @olivierpertz.bsky.social! i always thought nuclei were spherical but they are pancakes???? so much more to see in 3d, but data volume produced is insane, we will have to rethink our analysis pipelines. tips welcome! here shown in @napari.org
July 26, 2025 at 8:29 AM
first data from the new LLSM in PertzLab @olivierpertz.bsky.social! i always thought nuclei were spherical but they are pancakes???? so much more to see in 3d, but data volume produced is insane, we will have to rethink our analysis pipelines. tips welcome! here shown in @napari.org