Anna Poetsch
@apoetsch.bsky.social
Computational Biologist at TU Dresden. Interested in how genomes encode their own stability.
Congratulations @vakil-takhaveev.bsky.social @sturlalab.bsky.social and everyone else involved. It was really a pleasure to play a small part in it. I am looking forward to celebrating the next time we meet!
New publication alert! Click-code-seq, our DNA-damage sequencing method, is now out! This tool can advance our understanding of aging, cancer and neurodegeneration. Huge thanks to the amazing collaborative team behind this! @sturlalab.bsky.social @ethz.ch
Mapping oxidatively damaged bases and abasic sites at single-nucleotide resolutions reveals transcription-related strand biases, patterns mirroring cancer mutational signatures, and the action of anticancer drug irofulven
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 4, 2025 at 6:24 AM
Congratulations @vakil-takhaveev.bsky.social @sturlalab.bsky.social and everyone else involved. It was really a pleasure to play a small part in it. I am looking forward to celebrating the next time we meet!
Reposted by Anna Poetsch
Click-code-seq reveals strand biases of DNA oxidation and depurination in human genome. #DNAoxidation #HumanGenome @natchembio.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 2, 2025 at 9:31 AM
Click-code-seq reveals strand biases of DNA oxidation and depurination in human genome. #DNAoxidation #HumanGenome @natchembio.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Anna Poetsch
I am looking to get my hands on some #Illumina 5-base methylation data - does anyone have a bam file that I could use for some testing? Please RT for reach!
October 21, 2025 at 9:36 AM
I am looking to get my hands on some #Illumina 5-base methylation data - does anyone have a bam file that I could use for some testing? Please RT for reach!
It was a pleasure to talk Genome Stability for a few days with the DFG - FOR5504 for. It is really exciting to see the community in and around Cologne looking for genome stability in whole organisms and the context of the sequence. I am excited about what else is going to come.
Amazing retreat of the @dfg.de Research Unit FOR5504 on the Physiological Causes and Consequences of Genome Instability and the Institute for Genome Stability in Aging and Disease with keynotes by @apoetsch.bsky.social and @garinis.bsky.social
October 1, 2025 at 9:25 AM
It was a pleasure to talk Genome Stability for a few days with the DFG - FOR5504 for. It is really exciting to see the community in and around Cologne looking for genome stability in whole organisms and the context of the sequence. I am excited about what else is going to come.
Me: I got a new type of compliment from an audience member: "Your talk was so Gen Z"
My lab: This was not a compliment...
Me: 🥲 (but..., but..., I still think it was meant to be one...)
My lab: This was not a compliment...
Me: 🥲 (but..., but..., I still think it was meant to be one...)
September 27, 2025 at 11:16 AM
Me: I got a new type of compliment from an audience member: "Your talk was so Gen Z"
My lab: This was not a compliment...
Me: 🥲 (but..., but..., I still think it was meant to be one...)
My lab: This was not a compliment...
Me: 🥲 (but..., but..., I still think it was meant to be one...)
Reposted by Anna Poetsch
I am happy to share some thoughts on using AI to generate viruses (in German). www.spiegel.de/wissenschaft...
(S+) Künstliche Intelligenz: KI-designtes Virus tötet Kolibakterien
US-Forscher haben mithilfe von künstlicher Intelligenz Viren hergestellt und ihnen bestimmte Eigenschaften gegeben, weltweit sind sie damit wohl die Ersten. Die Möglichkeit KI-generierten Lebens schei...
www.spiegel.de
September 25, 2025 at 1:06 PM
I am happy to share some thoughts on using AI to generate viruses (in German). www.spiegel.de/wissenschaft...
Reposted by Anna Poetsch
The ARD Wissenschaftsredaktion talked to me about AI generated viruses. Interested? Here you can listen to it (in German). www.swr.de/leben/gesund...
Die ersten KI-generierten Viren als Hoffnung im Kampf gegen resistente Bakterien
Forschende aus Stanford haben erstmals Viren entwickelt, die von einer KI entworfen wurden. Einige dieser KI-Viren konnten antibiotikaresistente Bakterien infizieren und abtöten - ein möglicher Durchb...
www.swr.de
September 25, 2025 at 1:11 PM
The ARD Wissenschaftsredaktion talked to me about AI generated viruses. Interested? Here you can listen to it (in German). www.swr.de/leben/gesund...
There is a new Master of Physics of Life in the house. Congratulations, Adnan! Well done! It was really a superb Defense!
@poldresden.bsky.social
@poldresden.bsky.social
September 25, 2025 at 1:14 PM
There is a new Master of Physics of Life in the house. Congratulations, Adnan! Well done! It was really a superb Defense!
@poldresden.bsky.social
@poldresden.bsky.social
The ARD Wissenschaftsredaktion talked to me about AI generated viruses. Interested? Here you can listen to it (in German). www.swr.de/leben/gesund...
Die ersten KI-generierten Viren als Hoffnung im Kampf gegen resistente Bakterien
Forschende aus Stanford haben erstmals Viren entwickelt, die von einer KI entworfen wurden. Einige dieser KI-Viren konnten antibiotikaresistente Bakterien infizieren und abtöten - ein möglicher Durchb...
www.swr.de
September 25, 2025 at 1:11 PM
The ARD Wissenschaftsredaktion talked to me about AI generated viruses. Interested? Here you can listen to it (in German). www.swr.de/leben/gesund...
I am happy to share some thoughts on using AI to generate viruses (in German). www.spiegel.de/wissenschaft...
(S+) Künstliche Intelligenz: KI-designtes Virus tötet Kolibakterien
US-Forscher haben mithilfe von künstlicher Intelligenz Viren hergestellt und ihnen bestimmte Eigenschaften gegeben, weltweit sind sie damit wohl die Ersten. Die Möglichkeit KI-generierten Lebens schei...
www.spiegel.de
September 25, 2025 at 1:06 PM
I am happy to share some thoughts on using AI to generate viruses (in German). www.spiegel.de/wissenschaft...
Dear CRC TRR 341, thanks for having me. It was fascinating to learn more about the genomes of plants in their ecological context!
Our 5th Internal Progress Colloquium is coming to an end! Two days full of scientific interactions. Honoured to have with us Caroline Müller (Bielefeld University) and @apoetsch.bsky.social! Our ECRs have progressed enormously and this makes us so happy!
September 25, 2025 at 10:06 AM
Dear CRC TRR 341, thanks for having me. It was fascinating to learn more about the genomes of plants in their ecological context!
Reposted by Anna Poetsch
Would you like to do some unique experiments in cancer genomics and mutagenesis, in beautiful Munich? Well then apply for this PhD position: jobs.dkfz.de/en/jobs/1679...
You'll learn a lot and it'll be fun and interesting!
#DKTK @dkfz.bsky.social @lmumuenchen.bsky.social
You'll learn a lot and it'll be fun and interesting!
#DKTK @dkfz.bsky.social @lmumuenchen.bsky.social
PhD Student in Mutational Processes Driving Somatic Evolution
jobs.dkfz.de
August 19, 2025 at 2:54 PM
Would you like to do some unique experiments in cancer genomics and mutagenesis, in beautiful Munich? Well then apply for this PhD position: jobs.dkfz.de/en/jobs/1679...
You'll learn a lot and it'll be fun and interesting!
#DKTK @dkfz.bsky.social @lmumuenchen.bsky.social
You'll learn a lot and it'll be fun and interesting!
#DKTK @dkfz.bsky.social @lmumuenchen.bsky.social
Exciting to see the @grunewaldlab.bsky.social finding new target candidates against metastases of Ewing sarcoma.
It makes one wonder how general this pathway disruption might be and whether it may work with other sarcomas or metastatic cancers in general… 🤔
It makes one wonder how general this pathway disruption might be and whether it may work with other sarcomas or metastatic cancers in general… 🤔
Very proud on our stellar Alina Ritter for her frist first-author paper:
Targeting CXADR-mediated AKT signaling suppresses tumorigenesis and enhances #chemotherapy efficacy in #Ewing #sarcoma
tinyurl.com/3kcs3bc9
@dkfz.bsky.social
@uniheidelberg.bsky.social
@nct-heidelberg.bsky.social
Targeting CXADR-mediated AKT signaling suppresses tumorigenesis and enhances #chemotherapy efficacy in #Ewing #sarcoma
tinyurl.com/3kcs3bc9
@dkfz.bsky.social
@uniheidelberg.bsky.social
@nct-heidelberg.bsky.social
August 12, 2025 at 4:00 PM
Exciting to see the @grunewaldlab.bsky.social finding new target candidates against metastases of Ewing sarcoma.
It makes one wonder how general this pathway disruption might be and whether it may work with other sarcomas or metastatic cancers in general… 🤔
It makes one wonder how general this pathway disruption might be and whether it may work with other sarcomas or metastatic cancers in general… 🤔
We are happy to present a new paper on gastric tumour evolution in response to peri-operative chemotherapy. www.biorxiv.org/content/10.1... 🧵 1/6
Tumor clone dynamics in gastro-esophageal cancer organoids reveal a non-genetic memory of neoadjuvant chemotherapy via downregulation of NFκB signaling
Adenocarcinomas of the gastroesophageal junction exhibit genetic and non-genetic heterogeneity that impact clinical outcomes, though the underlying mechanisms behind drug resistance remain poorly unde...
www.biorxiv.org
July 31, 2025 at 6:28 AM
We are happy to present a new paper on gastric tumour evolution in response to peri-operative chemotherapy. www.biorxiv.org/content/10.1... 🧵 1/6
We are happy to present a new paper on the sequence dependence of 🧬-double strand breaks. www.biorxiv.org/content/10.1...
🧵 1/4
🧵 1/4
Using the DNA language model, GROVER, to parse sequence and epigenetic effects on genome stability
Genome stability is shaped by DNA sequence and epigenomic context, but their relative contributions to double-strand break (DSB) sensitivity remain unclear. We show that the DNA language model, GROVER...
www.biorxiv.org
July 30, 2025 at 2:11 PM
We are happy to present a new paper on the sequence dependence of 🧬-double strand breaks. www.biorxiv.org/content/10.1...
🧵 1/4
🧵 1/4
Reposted by Anna Poetsch
This week, we are highlighting Helena Jambor, a prolific contributor to our community sites @the-node.bsky.social and
@focalplane.bsky.social, as an extraordinary biologist. #100biologists
@helenajambor.bsky.social
@focalplane.bsky.social, as an extraordinary biologist. #100biologists
@helenajambor.bsky.social
July 17, 2025 at 2:03 PM
This week, we are highlighting Helena Jambor, a prolific contributor to our community sites @the-node.bsky.social and
@focalplane.bsky.social, as an extraordinary biologist. #100biologists
@helenajambor.bsky.social
@focalplane.bsky.social, as an extraordinary biologist. #100biologists
@helenajambor.bsky.social
Reposted by Anna Poetsch
🚨 #JobAlert. please share: The DRESDEN-concept Genome Center (DcGC) 🧬 @dcgenomecenter.bsky.social is looking for the new Head of Facility!
🗓️ Deadline for applications: August 11
More information here ➡️ tud.link/fz5hr8
@tudresden.bsky.social @mpi-cbg.de
🗓️ Deadline for applications: August 11
More information here ➡️ tud.link/fz5hr8
@tudresden.bsky.social @mpi-cbg.de
July 8, 2025 at 11:03 AM
🚨 #JobAlert. please share: The DRESDEN-concept Genome Center (DcGC) 🧬 @dcgenomecenter.bsky.social is looking for the new Head of Facility!
🗓️ Deadline for applications: August 11
More information here ➡️ tud.link/fz5hr8
@tudresden.bsky.social @mpi-cbg.de
🗓️ Deadline for applications: August 11
More information here ➡️ tud.link/fz5hr8
@tudresden.bsky.social @mpi-cbg.de
We have several open postdoc positions! We do computational biology 🧬🖥️ and deep learning to understand the genomics of genome instability and (somatic) genome evolution in ageing and cancer. Interested? 👉🏻 more details: tu-dresden.de/cmcb/biotec/...
Open positions
We are looking for Postdocs!
If you are interested in the lab in general as a postdoc, please feel free to apply with an open application, including a letter of motivation and a CV …
tu-dresden.de
June 26, 2025 at 9:46 AM
We have several open postdoc positions! We do computational biology 🧬🖥️ and deep learning to understand the genomics of genome instability and (somatic) genome evolution in ageing and cancer. Interested? 👉🏻 more details: tu-dresden.de/cmcb/biotec/...
Reposted by Anna Poetsch
Reposted by Anna Poetsch
@odedrechavi.bsky.social says he wants to change science for the better.
How? I’m still not quite sure. But 1.5 days into #TCTeAC, the plan seems to involve, among other things, walk-up songs, jumping, dancing, and a hefty serving of joy.
How? I’m still not quite sure. But 1.5 days into #TCTeAC, the plan seems to involve, among other things, walk-up songs, jumping, dancing, and a hefty serving of joy.
June 11, 2025 at 1:37 PM
@odedrechavi.bsky.social says he wants to change science for the better.
How? I’m still not quite sure. But 1.5 days into #TCTeAC, the plan seems to involve, among other things, walk-up songs, jumping, dancing, and a hefty serving of joy.
How? I’m still not quite sure. But 1.5 days into #TCTeAC, the plan seems to involve, among other things, walk-up songs, jumping, dancing, and a hefty serving of joy.
@helenajambor.bsky.social
Making a point about the importance of data visualization.
#theconferencetoendallconferences
#TCTEaC
Making a point about the importance of data visualization.
#theconferencetoendallconferences
#TCTEaC
June 10, 2025 at 5:21 PM
@helenajambor.bsky.social
Making a point about the importance of data visualization.
#theconferencetoendallconferences
#TCTEaC
Making a point about the importance of data visualization.
#theconferencetoendallconferences
#TCTEaC
Reposted by Anna Poetsch
The deadline for the VIB.AI group leader positions is approaching - send in your CV and short research plan before 14th June to start your BioML research lab in Leuven or Ghent
We want to connect:
To link model builders with data generators.
To bring together scientists asking why cells behave the way they do, and others figuring out how to model that behavior.
If you're working on AI in biology, consider joining!
https://tinyurl.com/y35m6khy
To link model builders with data generators.
To bring together scientists asking why cells behave the way they do, and others figuring out how to model that behavior.
If you're working on AI in biology, consider joining!
https://tinyurl.com/y35m6khy
June 4, 2025 at 7:16 AM
The deadline for the VIB.AI group leader positions is approaching - send in your CV and short research plan before 14th June to start your BioML research lab in Leuven or Ghent
Reposted by Anna Poetsch
We are recruiting! Senior postdoc in computational cancer genomics/epigenomics @ludwigcancer.bsky.social @ox.ac.uk. Lead research into epigenetic drivers of secondary AML with rich omics data + strong clinical/wet-lab collaborations.
cutt.cx/YUoB
We look forward hearing from you!
#epigenetics #jobs
cutt.cx/YUoB
We look forward hearing from you!
#epigenetics #jobs
April 28, 2025 at 2:59 PM
We are recruiting! Senior postdoc in computational cancer genomics/epigenomics @ludwigcancer.bsky.social @ox.ac.uk. Lead research into epigenetic drivers of secondary AML with rich omics data + strong clinical/wet-lab collaborations.
cutt.cx/YUoB
We look forward hearing from you!
#epigenetics #jobs
cutt.cx/YUoB
We look forward hearing from you!
#epigenetics #jobs
Reposted by Anna Poetsch
Are you interested in combing machine learning and 🧬 language models with multi-omics data to study somatic genome evolution?
We have several open postdoc positions and look forward to hearing from you!
tu-dresden.de/cmcb/biotec/...
🧬🖥️
We have several open postdoc positions and look forward to hearing from you!
tu-dresden.de/cmcb/biotec/...
🧬🖥️
Open positions
We are looking for Postdocs!
If you are interested in the lab in general as a postdoc, please feel free to apply with an open application, including a letter of motivation and a CV …
tu-dresden.de
April 11, 2025 at 9:40 AM
Are you interested in combing machine learning and 🧬 language models with multi-omics data to study somatic genome evolution?
We have several open postdoc positions and look forward to hearing from you!
tu-dresden.de/cmcb/biotec/...
🧬🖥️
We have several open postdoc positions and look forward to hearing from you!
tu-dresden.de/cmcb/biotec/...
🧬🖥️
Reposted by Anna Poetsch
🚨 #JobAlert
Postdoc positions in @apoetsch.bsky.social group at BIOTEC. Combine #AI and #LLM with #omics data to study #genomics.
More info ⬇️⬇️
Postdoc positions in @apoetsch.bsky.social group at BIOTEC. Combine #AI and #LLM with #omics data to study #genomics.
More info ⬇️⬇️
Are you interested in combing machine learning and 🧬 language models with multi-omics data to study somatic genome evolution?
We have several open postdoc positions and look forward to hearing from you!
tu-dresden.de/cmcb/biotec/...
🧬🖥️
We have several open postdoc positions and look forward to hearing from you!
tu-dresden.de/cmcb/biotec/...
🧬🖥️
Open positions
We are looking for Postdocs!
If you are interested in the lab in general as a postdoc, please feel free to apply with an open application, including a letter of motivation and a CV …
tu-dresden.de
April 11, 2025 at 1:18 PM