Span
@anna2.bsky.social
spanning with spandrels whiles tnetting on 'kneedles
Rita Levi-Montalcini
Thanks for highlighting, this lady’s career is fascinating. “one of the first scientists to point out the importance of the mast cell in human pathology.”
Thanks for highlighting, this lady’s career is fascinating. “one of the first scientists to point out the importance of the mast cell in human pathology.”
Love this tradition @ohiostatepress.bsky.social. Promoted faculty pick a book and write a dedication. 🧪💚🧪 Here is mine from my promotion to Professor in 2025.
February 15, 2026 at 6:04 PM
Rita Levi-Montalcini
Thanks for highlighting, this lady’s career is fascinating. “one of the first scientists to point out the importance of the mast cell in human pathology.”
Thanks for highlighting, this lady’s career is fascinating. “one of the first scientists to point out the importance of the mast cell in human pathology.”
Reposted by Span
Prevention may have wider spillovers than we thought: Eric Topol explores the evidence that older adults who received a shingles vaccine had a roughly 20% lower risk of developing dementia in later years buff.ly/iuMmX9U
#ShareGoodNewsToo
#ShareGoodNewsToo
Spotlight on the Shingles Vaccine—Again!
Two new studies add to a remarkable body of evidence for benefit
buff.ly
February 14, 2026 at 2:50 PM
Prevention may have wider spillovers than we thought: Eric Topol explores the evidence that older adults who received a shingles vaccine had a roughly 20% lower risk of developing dementia in later years buff.ly/iuMmX9U
#ShareGoodNewsToo
#ShareGoodNewsToo
1490s 💫
reading @adapalmer.bsky.social book Inventing the Renaissance, I lately learn “the #earlymodern “ could be that old* too
*for some
reading @adapalmer.bsky.social book Inventing the Renaissance, I lately learn “the #earlymodern “ could be that old* too
*for some
And here is the paper astrolabe that is included into the binding of the so-called "Heidelberger Schicksalsbuch". This paper instrument left the highlighted lasting impression on the nearby blank pages. #bookhistory #histsci
2/2
2/2
February 3, 2026 at 3:43 PM
1490s 💫
reading @adapalmer.bsky.social book Inventing the Renaissance, I lately learn “the #earlymodern “ could be that old* too
*for some
reading @adapalmer.bsky.social book Inventing the Renaissance, I lately learn “the #earlymodern “ could be that old* too
*for some
Apt
2/
"I can choose to exceed my limits, but I can’t choose to recover from exceeding them, and telling me to try is like telling a diabetic who’s being forced to eat a box of fudge to “try” not to become hyperglycaemic"
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME #PEM
"I can choose to exceed my limits, but I can’t choose to recover from exceeding them, and telling me to try is like telling a diabetic who’s being forced to eat a box of fudge to “try” not to become hyperglycaemic"
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME #PEM
February 2, 2026 at 7:00 AM
Apt
“it can be hard not to marvel at certain empirical blind spots that ought not have been there by the middle of the twentieth century.”
Yah. Jaw dropping to glimpse the mirror mid century researchers held up to themselves when writing about women patients .
Yah. Jaw dropping to glimpse the mirror mid century researchers held up to themselves when writing about women patients .
@tomzellerjr.com explores how medical misogyny impacted the practice of neuroscience (and the treatment of migraines).
How Medical Misogyny Impacted the Treatment of Women’s Migraines
“I get ocular migraines, so they’re behind my eyes. And I can’t do anything when it’s bad. Like, even like the smallest light or the lightest noise sets me off. I wear sunglasses everywhere. It’s j…
buff.ly
January 14, 2026 at 11:04 PM
“it can be hard not to marvel at certain empirical blind spots that ought not have been there by the middle of the twentieth century.”
Yah. Jaw dropping to glimpse the mirror mid century researchers held up to themselves when writing about women patients .
Yah. Jaw dropping to glimpse the mirror mid century researchers held up to themselves when writing about women patients .
Reposted by Span
The idea that getting surviving a disease is proof of strength and fitness has deep and largely disgusting roots in American history (see Olivarius’ book). In this case, they are drawing the lOgIcAl conclusion that needless exposure to disease is therefore a valuable test of strength…
January 11, 2026 at 5:12 PM
The idea that getting surviving a disease is proof of strength and fitness has deep and largely disgusting roots in American history (see Olivarius’ book). In this case, they are drawing the lOgIcAl conclusion that needless exposure to disease is therefore a valuable test of strength…
Reposted by Span
People distrust healthcare, and often it's not the medicine itself. It's because of exceptionally negative experiences with medical "professionals." I'm a white male. And even I have experienced doctors treating me like total garbage. Makes me scared of how marginalized people are treated.
December 19, 2025 at 3:29 PM
People distrust healthcare, and often it's not the medicine itself. It's because of exceptionally negative experiences with medical "professionals." I'm a white male. And even I have experienced doctors treating me like total garbage. Makes me scared of how marginalized people are treated.
”Long COVID is sometimes described as an anything-goes sequela.
This study shows the opposite.
A consistent, reproducible biological signature across independent cohorts.“
(from the Zdenek tweet thread on the nature paper)
This study shows the opposite.
A consistent, reproducible biological signature across independent cohorts.“
(from the Zdenek tweet thread on the nature paper)
Direct link to the article mentioned above:
Long COVID involves activation of proinflammatory and immune exhaustion pathways (Dec 12, 2025)
www.nature.com/articles/s41...
[ Free PDF available ]
Long COVID involves activation of proinflammatory and immune exhaustion pathways (Dec 12, 2025)
www.nature.com/articles/s41...
[ Free PDF available ]
Long COVID involves activation of proinflammatory and immune exhaustion pathways - Nature Immunology
Long COVID (LC) involves a spectrum of chronic symptoms after resolution of acute severe acute respiratory syndrome coronavirus 2 infection. Barouch and colleagues show that LC is characterized by per...
www.nature.com
December 12, 2025 at 10:33 PM
”Long COVID is sometimes described as an anything-goes sequela.
This study shows the opposite.
A consistent, reproducible biological signature across independent cohorts.“
(from the Zdenek tweet thread on the nature paper)
This study shows the opposite.
A consistent, reproducible biological signature across independent cohorts.“
(from the Zdenek tweet thread on the nature paper)
Reposted by Span
In this week’s TPWKY book club episode, Dr. Homer Venters joins us to discuss his latest work, Outbreak Behind Bars: Spider Bites, Human Rights, and the Unseen Danger to Public Health. Dr. Venters has extensive firsthand knowledge of the barriers in care - and he has evidence-based solutions.
December 9, 2025 at 3:03 PM
In this week’s TPWKY book club episode, Dr. Homer Venters joins us to discuss his latest work, Outbreak Behind Bars: Spider Bites, Human Rights, and the Unseen Danger to Public Health. Dr. Venters has extensive firsthand knowledge of the barriers in care - and he has evidence-based solutions.
Reposted by Span
A few charts we created for this analysis.
November 21, 2025 at 2:33 PM
A few charts we created for this analysis.
Had an exchange not so long ago here on when neuroplasticity approach appropriate. The cause of illness accurately recognised (e.g. a discrete lesion) and not as a cure for impairment but to improve quality of life, post CNS injury for example. Misapplications harm reputation.
They include a bit about Deacon discussing the idea of people being insulted by the neuroplasticity approach. "There might be a tendency to double down on your I am sick and I am having these symptoms and reluctance or resistance to an open mind."
November 21, 2025 at 5:21 PM
Had an exchange not so long ago here on when neuroplasticity approach appropriate. The cause of illness accurately recognised (e.g. a discrete lesion) and not as a cure for impairment but to improve quality of life, post CNS injury for example. Misapplications harm reputation.
Reposted by Span
2) The authors started with data in the UK Biobank. They looked for cases with MS, Crohn's disease, ulcerative colitis, and atopic dermatitis using their ICD-10 health records.
Next, they used the genetic data of these participants to screen for disease–causing mutations.
Next, they used the genetic data of these participants to screen for disease–causing mutations.
October 28, 2025 at 8:27 AM
2) The authors started with data in the UK Biobank. They looked for cases with MS, Crohn's disease, ulcerative colitis, and atopic dermatitis using their ICD-10 health records.
Next, they used the genetic data of these participants to screen for disease–causing mutations.
Next, they used the genetic data of these participants to screen for disease–causing mutations.
Reposted by Span
(kindly share)
I'm selling photos to raise money private medical help for a severe - quite lifeshortening - immune damaging disease I have, #MECFS, outside the coverage of public health.
There are some good nature photos in any event ;)
More info here:
payhip.com/MiskaKnapek/...
I'm selling photos to raise money private medical help for a severe - quite lifeshortening - immune damaging disease I have, #MECFS, outside the coverage of public health.
There are some good nature photos in any event ;)
More info here:
payhip.com/MiskaKnapek/...
July 27, 2025 at 8:36 AM
(kindly share)
I'm selling photos to raise money private medical help for a severe - quite lifeshortening - immune damaging disease I have, #MECFS, outside the coverage of public health.
There are some good nature photos in any event ;)
More info here:
payhip.com/MiskaKnapek/...
I'm selling photos to raise money private medical help for a severe - quite lifeshortening - immune damaging disease I have, #MECFS, outside the coverage of public health.
There are some good nature photos in any event ;)
More info here:
payhip.com/MiskaKnapek/...
Interesting work. "we analyzed viral load of 31 DNA viruses in human blood and saliva using whole-genome sequencing from UK Biobank (n=490k), SPARK (n=13k), and All of Us (n=415k)... genetic variation at dozens of loci associated with load of seven viruses"
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Genes and environment profoundly affect the human virome
Many viruses have adapted to persist in infected humans for life. Variable host control of their abundance (or load) can lead to clearance or disease. Here, we analyzed the viral load of 31 DNA viruse...
www.biorxiv.org
September 13, 2025 at 9:22 PM
Reposted by Span
Last ep, we took you through all the ways that cold can harm us. Ending the story there would be skipping over the parts where cold is the hero, rather than the villain. In the second of this frosty miniseries, we explore situations in which we might use cold to protect us and how it actually
works.
works.
September 11, 2025 at 4:03 AM
Last ep, we took you through all the ways that cold can harm us. Ending the story there would be skipping over the parts where cold is the hero, rather than the villain. In the second of this frosty miniseries, we explore situations in which we might use cold to protect us and how it actually
works.
works.
Reposted by Span
A very important point! When my cognitive stuff started making long form reading intermittently impossible, I adopted a variety of tools to still engage w/ my craft: audiobooks, graphic novels, short fiction, film adaptations of books & plays, the mix has & hones the tools of writing really well 1/2
August 9, 2025 at 6:19 PM
A very important point! When my cognitive stuff started making long form reading intermittently impossible, I adopted a variety of tools to still engage w/ my craft: audiobooks, graphic novels, short fiction, film adaptations of books & plays, the mix has & hones the tools of writing really well 1/2
Reposted by Span
A report from @aarp.org and the National Alliance for Caregiving shows that more than 63 million Americans are serving as family caregivers — and they’re managing financial risks, poor health and isolation.
The number of family caregivers is surging
A new report from AARP and the National Alliance for Caregiving shows that more than 63 million Americans are serving as family caregivers — and they’re managing financial risks, poor health and isola...
19thnews.org
July 28, 2025 at 5:13 PM
A report from @aarp.org and the National Alliance for Caregiving shows that more than 63 million Americans are serving as family caregivers — and they’re managing financial risks, poor health and isolation.
Reposted by Span
TW: New Sunday Times investigation hundreds of parents, falsely accused of Fabricated or Induced Illness when seeking care for their children - abuse allegations, risk losing access, and waiting months to be cleared— some children worsened and even died.
archive.ph/2025.07.19-1...
archive.ph/2025.07.19-1...
July 19, 2025 at 11:01 PM
TW: New Sunday Times investigation hundreds of parents, falsely accused of Fabricated or Induced Illness when seeking care for their children - abuse allegations, risk losing access, and waiting months to be cleared— some children worsened and even died.
archive.ph/2025.07.19-1...
archive.ph/2025.07.19-1...
Reposted by Span
New website in the UK
ME Genetics Centre of Excellence
megenetics.org.uk
Hopefully this group will get enough funding from somewhere to continue their work following the publication of the DecodeME research soon
#MEcfs #CFS
ME Genetics Centre of Excellence
megenetics.org.uk
Hopefully this group will get enough funding from somewhere to continue their work following the publication of the DecodeME research soon
#MEcfs #CFS
June 6, 2025 at 3:18 PM
New website in the UK
ME Genetics Centre of Excellence
megenetics.org.uk
Hopefully this group will get enough funding from somewhere to continue their work following the publication of the DecodeME research soon
#MEcfs #CFS
ME Genetics Centre of Excellence
megenetics.org.uk
Hopefully this group will get enough funding from somewhere to continue their work following the publication of the DecodeME research soon
#MEcfs #CFS
Is there a medically acknowledged paradigm where an inborn error of metabolism in a previously normal adult/teenager can be triggered by unremarkable infection into a terminal illness? Note, not a prion disease.
A Case Study of Dysfunctional Nicotinamide Metabolism in a 20-Year-Old Male #NNMT #NAD #NADH #MECFS #LongCovid
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
A Case Study of Dysfunctional Nicotinamide Metabolism in a 20-Year-Old Male
We present a case study of a 20-year-old male with an unknown neurodegenerative disease who was referred to the Undiagnosed Diseases Network Vanderbilt Medical Center site. A previous metabolic panel ...
pmc.ncbi.nlm.nih.gov
May 29, 2025 at 8:13 PM
Is there a medically acknowledged paradigm where an inborn error of metabolism in a previously normal adult/teenager can be triggered by unremarkable infection into a terminal illness? Note, not a prion disease.
Reposted by Span
The book is called The Creatures' Guide to Caring, and it'll be out sometime in early 2026. You can get updates by following me here or subscribing to my newsletter: elizabethgpreston.substack.com Thanks!
Inkfish | Elizabeth Preston | Substack
Advice of questionable relevance from the animal kingdom (plus updates about my writing). Click to read Inkfish, by Elizabeth Preston, a Substack publication. Launched 7 months ago.
elizabethgpreston.substack.com
April 21, 2025 at 9:29 PM
The book is called The Creatures' Guide to Caring, and it'll be out sometime in early 2026. You can get updates by following me here or subscribing to my newsletter: elizabethgpreston.substack.com Thanks!
👋 hello from New Zealand
Is there any way to preorder the audiobook here? All retailers say not available in your country.
Is there any way to preorder the audiobook here? All retailers say not available in your country.
Time is rapidly coming up to fast approaching the publication of THE DECLINE AND FALL OF THE HUMAN EMPIRE. But why wait? You can pre-order it now. 'Put this at the head of your reading lists immediately people. Before it’s too late' – Eric Idle www.panmacmillan.com/authors/henr...
The Decline and Fall of the Human Empire by Henry Gee
Find out more about The Decline and Fall of the Human Empire by Henry Gee
www.panmacmillan.com
February 12, 2025 at 4:09 AM
👋 hello from New Zealand
Is there any way to preorder the audiobook here? All retailers say not available in your country.
Is there any way to preorder the audiobook here? All retailers say not available in your country.
