Ander Movilla
@andermovilla.bsky.social
Mathematical/physical/computational biologist. Postdoc @johninnescentre.bsky.social. Mostly about Science, occasionally something else. Opinions my own, even when wrong.
Reposted by Ander Movilla
How much carbon budget do we have left if we want to stay below 1.5˚C?
Just 2 more years at current rates. It is essentially impossible to avoid global temperature rise exceeding 1.5˚C.
climatelabbook.substack.com/p/the-shrink...
Just 2 more years at current rates. It is essentially impossible to avoid global temperature rise exceeding 1.5˚C.
climatelabbook.substack.com/p/the-shrink...
November 13, 2025 at 1:19 PM
How much carbon budget do we have left if we want to stay below 1.5˚C?
Just 2 more years at current rates. It is essentially impossible to avoid global temperature rise exceeding 1.5˚C.
climatelabbook.substack.com/p/the-shrink...
Just 2 more years at current rates. It is essentially impossible to avoid global temperature rise exceeding 1.5˚C.
climatelabbook.substack.com/p/the-shrink...
Reposted by Ander Movilla
📣 Looking for a 3-Year Postdoc @johninnescentre.bsky.social to join my Wellcome project.
This is a highly interdisciplinary project that explores chromatin dynamics in 🌱 plant responses across timescales, from circadian rhythms to seasonal changes
📅 Closes on 10 Dec.
www.jic.ac.uk/vacancies/36...
This is a highly interdisciplinary project that explores chromatin dynamics in 🌱 plant responses across timescales, from circadian rhythms to seasonal changes
📅 Closes on 10 Dec.
www.jic.ac.uk/vacancies/36...
Postdoctoral Researcher (Dr Miguel Montez) | John Innes Centre
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Wellcome Trust project led by Dr Miguel Montez and hosted within the Dodd Group at the John Innes Centre.
www.jic.ac.uk
November 13, 2025 at 8:34 AM
📣 Looking for a 3-Year Postdoc @johninnescentre.bsky.social to join my Wellcome project.
This is a highly interdisciplinary project that explores chromatin dynamics in 🌱 plant responses across timescales, from circadian rhythms to seasonal changes
📅 Closes on 10 Dec.
www.jic.ac.uk/vacancies/36...
This is a highly interdisciplinary project that explores chromatin dynamics in 🌱 plant responses across timescales, from circadian rhythms to seasonal changes
📅 Closes on 10 Dec.
www.jic.ac.uk/vacancies/36...
Reposted by Ander Movilla
Exciting @centuri-ls.bsky.social internal seminar by @efeilker-phys.bsky.social on energetics and scaling during development 🤩
November 4, 2025 at 8:03 AM
Exciting @centuri-ls.bsky.social internal seminar by @efeilker-phys.bsky.social on energetics and scaling during development 🤩
Reposted by Ander Movilla
🚨 Exciting conference for stem cell aficionados!
‘Frontiers in Stem Cell Innovation’ will bring together experts in stem cell biology from academia & industry to discuss key developments as well as challenges in regenerative medicine and disease modelling.
fisci2026.eventbrite.co.uk
Please repost 🙏
‘Frontiers in Stem Cell Innovation’ will bring together experts in stem cell biology from academia & industry to discuss key developments as well as challenges in regenerative medicine and disease modelling.
fisci2026.eventbrite.co.uk
Please repost 🙏
Frontiers in Stem Cell Innovation 2026
Join leading academics and industry professionals exploring cutting-edge stem cell technologies and disease modelling for drug discovery
FISCI2026.eventbrite.co.uk
November 1, 2025 at 8:56 PM
🚨 Exciting conference for stem cell aficionados!
‘Frontiers in Stem Cell Innovation’ will bring together experts in stem cell biology from academia & industry to discuss key developments as well as challenges in regenerative medicine and disease modelling.
fisci2026.eventbrite.co.uk
Please repost 🙏
‘Frontiers in Stem Cell Innovation’ will bring together experts in stem cell biology from academia & industry to discuss key developments as well as challenges in regenerative medicine and disease modelling.
fisci2026.eventbrite.co.uk
Please repost 🙏
Reposted by Ander Movilla
1/ 🚀 AEBP2 isn’t what we thought.
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
October 31, 2025 at 10:53 AM
1/ 🚀 AEBP2 isn’t what we thought.
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
Reposted by Ander Movilla
Two 2-year postdoc positions in my theory group — for studying the interplay between metabolism and morphogenesis at the edge of the Calanques and the Mediterranean. More information can be found on: euraxess.ec.europa.eu/jobs/381176
#biophysics
#biophysics
Postdoc in Theoretical Biophysics
Two postdoc positions (each for two years, funded by Amidex Foundation) are available in theoretical biophysics within the theory group at DyNaMo (Aix-Marseille University).
euraxess.ec.europa.eu
October 27, 2025 at 4:19 PM
Two 2-year postdoc positions in my theory group — for studying the interplay between metabolism and morphogenesis at the edge of the Calanques and the Mediterranean. More information can be found on: euraxess.ec.europa.eu/jobs/381176
#biophysics
#biophysics
Reposted by Ander Movilla
📢 New preprint !
Please check if you are interested in the comparison between 2d and 3d nematic theories 🤔
I show that the 2d description can lead to artefacts on curved surfaces, and I propose a thin film description of nematic shells with full 3d orientation !
This was a funny summer project 😊
Please check if you are interested in the comparison between 2d and 3d nematic theories 🤔
I show that the 2d description can lead to artefacts on curved surfaces, and I propose a thin film description of nematic shells with full 3d orientation !
This was a funny summer project 😊
Mathieu Dedenon: Three-dimensional formulation of curved nematic shells https://arxiv.org/abs/2510.19412 https://arxiv.org/pdf/2510.19412 https://arxiv.org/html/2510.19412
October 23, 2025 at 10:49 AM
📢 New preprint !
Please check if you are interested in the comparison between 2d and 3d nematic theories 🤔
I show that the 2d description can lead to artefacts on curved surfaces, and I propose a thin film description of nematic shells with full 3d orientation !
This was a funny summer project 😊
Please check if you are interested in the comparison between 2d and 3d nematic theories 🤔
I show that the 2d description can lead to artefacts on curved surfaces, and I propose a thin film description of nematic shells with full 3d orientation !
This was a funny summer project 😊
Reposted by Ander Movilla
Check out our new work, led by talented @janhuemar.bsky.social, where we uncover that pioneer factor Oct4 remodels chromatin for DNA access not by opening it but by exploiting nucleosome breathing and forming clusters 🔥🔥🔥
🚨 🚨 🚨 New preprint alert!!! 🚨 🚨 🚨
In the past, we have learnt that Oct4 can induce nucleosome breathing on the mono-nucleosome level.
But what happens when you have a fibre of multiple nucleosomes?
www.biorxiv.org/content/10.1...
@rcollepardo.bsky.social @juliamaristany.bsky.social
In the past, we have learnt that Oct4 can induce nucleosome breathing on the mono-nucleosome level.
But what happens when you have a fibre of multiple nucleosomes?
www.biorxiv.org/content/10.1...
@rcollepardo.bsky.social @juliamaristany.bsky.social
October 22, 2025 at 5:10 AM
Check out our new work, led by talented @janhuemar.bsky.social, where we uncover that pioneer factor Oct4 remodels chromatin for DNA access not by opening it but by exploiting nucleosome breathing and forming clusters 🔥🔥🔥
Reposted by Ander Movilla
The Paris Agreement offers a powerful framework for a fairer, healthier world. But as extreme heat shows, every tenth of a degree matters. We need higher ambition to stop violating the rights of ever more people. - new @wwattribution.bsky.social study
www.worldweatherattribution.org/ten-years-of...
www.worldweatherattribution.org/ten-years-of...
October 16, 2025 at 11:12 AM
The Paris Agreement offers a powerful framework for a fairer, healthier world. But as extreme heat shows, every tenth of a degree matters. We need higher ambition to stop violating the rights of ever more people. - new @wwattribution.bsky.social study
www.worldweatherattribution.org/ten-years-of...
www.worldweatherattribution.org/ten-years-of...
Reposted by Ander Movilla
This work was led by Young Jun Kim, a very talented student in the lab. If you have ONT data and want to investigate DNA methylation, DMRcaller would be able to provide you more information than what was previously possible.
October 14, 2025 at 8:21 AM
This work was led by Young Jun Kim, a very talented student in the lab. If you have ONT data and want to investigate DNA methylation, DMRcaller would be able to provide you more information than what was previously possible.
Reposted by Ander Movilla
Biophysics Seminar will take place Today, 12pm, at ENS Physics Department, room L378 ( zoom link by DM).
Fabián Aguirre López (Centre d'Economie de la Sorbonne).
Patterns robust to Disorder in spatially-interacting Generalized Lotka-Volterra Ecosystems
Fabián Aguirre López (Centre d'Economie de la Sorbonne).
Patterns robust to Disorder in spatially-interacting Generalized Lotka-Volterra Ecosystems
October 10, 2025 at 7:12 AM
Biophysics Seminar will take place Today, 12pm, at ENS Physics Department, room L378 ( zoom link by DM).
Fabián Aguirre López (Centre d'Economie de la Sorbonne).
Patterns robust to Disorder in spatially-interacting Generalized Lotka-Volterra Ecosystems
Fabián Aguirre López (Centre d'Economie de la Sorbonne).
Patterns robust to Disorder in spatially-interacting Generalized Lotka-Volterra Ecosystems
Reposted by Ander Movilla
Wonderful opportunity to work with Martin Howard and my group trying to understand how chromatin influences gene transcription and expression. Integration of theory, modelling, and experimentation. Come and join the team!
Please repost!
jobs.jic.ac.uk/Details.asp?...
Please repost!
jobs.jic.ac.uk/Details.asp?...
John Innes Centre
jobs.jic.ac.uk
October 8, 2025 at 9:04 AM
Wonderful opportunity to work with Martin Howard and my group trying to understand how chromatin influences gene transcription and expression. Integration of theory, modelling, and experimentation. Come and join the team!
Please repost!
jobs.jic.ac.uk/Details.asp?...
Please repost!
jobs.jic.ac.uk/Details.asp?...
Reposted by Ander Movilla
If you are a computational biologist come, apply and join Howard & Klose lab in a joint Norwich-Oxford collaboration on chromatin dynamics!
VACANCY - We have an opportunity for a Postdoctoral Researcher to join the Howard Group, working to develop computational models of epigenetic dynamics in the Polycomb system.
www.jic.ac.uk/vacancies/po...
Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time
www.jic.ac.uk/vacancies/po...
Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time
Postdoctoral Researcher (Howard Group) | John Innes Centre
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Howard Group at the John Innes Centre, working on cutting-edge science in the field of Computational and Systems Biology.
www.jic.ac.uk
October 8, 2025 at 10:44 AM
If you are a computational biologist come, apply and join Howard & Klose lab in a joint Norwich-Oxford collaboration on chromatin dynamics!
Reposted by Ander Movilla
If you are a computational biologist interested in how chromatin states are established and maintained to regulate transcription, this is the dream job for you! This will be in close collaboration with the Klose lab in Oxford and we have a lot of cool projects you can get involved in. Apply!
VACANCY - We have an opportunity for a Postdoctoral Researcher to join the Howard Group, working to develop computational models of epigenetic dynamics in the Polycomb system.
www.jic.ac.uk/vacancies/po...
Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time
www.jic.ac.uk/vacancies/po...
Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time
Postdoctoral Researcher (Howard Group) | John Innes Centre
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Howard Group at the John Innes Centre, working on cutting-edge science in the field of Computational and Systems Biology.
www.jic.ac.uk
October 6, 2025 at 8:17 PM
If you are a computational biologist interested in how chromatin states are established and maintained to regulate transcription, this is the dream job for you! This will be in close collaboration with the Klose lab in Oxford and we have a lot of cool projects you can get involved in. Apply!
Reposted by Ander Movilla
After a long time in the making, my paper on nonequilibrium thermodynamics of Darwinian evolution has been published in Philosophical Transactions B. Updated version: arxiv.org/abs/2112.02809
October 7, 2025 at 9:33 AM
After a long time in the making, my paper on nonequilibrium thermodynamics of Darwinian evolution has been published in Philosophical Transactions B. Updated version: arxiv.org/abs/2112.02809
Very exciting opportunity for those with a quantitative background and interested in epigenetics / gene regulation. Highly collaborative environment!
VACANCY - We have an opportunity for a Postdoctoral Researcher to join the Howard Group, working to develop computational models of epigenetic dynamics in the Polycomb system.
www.jic.ac.uk/vacancies/po...
Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time
www.jic.ac.uk/vacancies/po...
Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time
Postdoctoral Researcher (Howard Group) | John Innes Centre
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Howard Group at the John Innes Centre, working on cutting-edge science in the field of Computational and Systems Biology.
www.jic.ac.uk
October 7, 2025 at 6:34 AM
Very exciting opportunity for those with a quantitative background and interested in epigenetics / gene regulation. Highly collaborative environment!
Reposted by Ander Movilla
New preprint from the lab !! Loop extrusion may provide mechanical robustness to chromatin. Great work by Hossein Salari. @cnrs.fr @lbmcinlyon.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Loop extrusion provides mechanical robustness to chromatin
Chromosomes are complex biopolymers folded into dynamic loops via a loop extrusion process and may experience various mechanical forces in vivo . We develop a force-dependent model of chromatin loop e...
www.biorxiv.org
September 29, 2025 at 1:24 PM
New preprint from the lab !! Loop extrusion may provide mechanical robustness to chromatin. Great work by Hossein Salari. @cnrs.fr @lbmcinlyon.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Ander Movilla
I'm really looking forward to visiting Norwich again and sharing my perspective on why plants are the most amazing and important organisms in the universe! 🌱💚
EVENT - Calling all teachers, A-level science classes and colleges! Registration is now open for the NBI Accessible Science Talks 2025
🗓️ Tuesday 7 October 2025
💻 Register here: jic.link/NBIAST2025
🗓️ Tuesday 7 October 2025
💻 Register here: jic.link/NBIAST2025
September 10, 2025 at 3:39 PM
I'm really looking forward to visiting Norwich again and sharing my perspective on why plants are the most amazing and important organisms in the universe! 🌱💚
Reposted by Ander Movilla
Delighted to share that I’ve been awarded the Wellcome Trust Early-Career Award 🙏 £1.4m over 5 years.
The start of an exciting new journey 🚀
The start of an exciting new journey 🚀
NEWS - Talented early-career researcher receives major @wellcometrust.bsky.social funding
The innovative research project of JIC early-career plant scientist, Dr @miguelmontez.bsky.social, has attracted a prestigious funding award from a global health charity.
www.jic.ac.uk/news/talente...
The innovative research project of JIC early-career plant scientist, Dr @miguelmontez.bsky.social, has attracted a prestigious funding award from a global health charity.
www.jic.ac.uk/news/talente...
Talented early-career researcher receives major Wellcome Trust funding | John Innes Centre
The innovative research project of an early-career plant scientist at the John Innes Centre has attracted a prestigious funding award from a global health charity…
www.jic.ac.uk
September 9, 2025 at 10:54 AM
Delighted to share that I’ve been awarded the Wellcome Trust Early-Career Award 🙏 £1.4m over 5 years.
The start of an exciting new journey 🚀
The start of an exciting new journey 🚀
Reposted by Ander Movilla
NEWS - Talented early-career researcher receives major @wellcometrust.bsky.social funding
The innovative research project of JIC early-career plant scientist, Dr @miguelmontez.bsky.social, has attracted a prestigious funding award from a global health charity.
www.jic.ac.uk/news/talente...
The innovative research project of JIC early-career plant scientist, Dr @miguelmontez.bsky.social, has attracted a prestigious funding award from a global health charity.
www.jic.ac.uk/news/talente...
Talented early-career researcher receives major Wellcome Trust funding | John Innes Centre
The innovative research project of an early-career plant scientist at the John Innes Centre has attracted a prestigious funding award from a global health charity…
www.jic.ac.uk
September 9, 2025 at 10:09 AM
NEWS - Talented early-career researcher receives major @wellcometrust.bsky.social funding
The innovative research project of JIC early-career plant scientist, Dr @miguelmontez.bsky.social, has attracted a prestigious funding award from a global health charity.
www.jic.ac.uk/news/talente...
The innovative research project of JIC early-career plant scientist, Dr @miguelmontez.bsky.social, has attracted a prestigious funding award from a global health charity.
www.jic.ac.uk/news/talente...
Reposted by Ander Movilla
Excited to share the paper from my work in the Dean lab @johninnescentre.bsky.social out now in @cp-molcell.bsky.social. Huge thanks to all the co-authors - it was a great collaborative effort! Watch out for the associated cover artwork coming out next week 🎉 www.cell.com/molecular-ce...
VEL-dependent polymerization maintains the chromatin association of Polycomb proteins for the switch to epigenetic silencing
Schulten et al. show that VEL polymerization domains produce higher-order protein
assemblies to maintain chromatin association of Polycomb proteins, enabling a stable
epigenetic switch at the floral r...
www.cell.com
August 26, 2025 at 6:04 PM
Excited to share the paper from my work in the Dean lab @johninnescentre.bsky.social out now in @cp-molcell.bsky.social. Huge thanks to all the co-authors - it was a great collaborative effort! Watch out for the associated cover artwork coming out next week 🎉 www.cell.com/molecular-ce...
Reposted by Ander Movilla
I wrote an "Open Questions" piece last year, trying to sum up things I have been thinking about on gene tuning and TFs dosage. In my view, much we don't know is cause we are lacking the tools - but maybe I'm biased as I was a tech developer. THX to the reviewer! :) doi.org/10.1098/rsob...
Transcriptional regulation as a dose-dependent process: insights from transcription factor tuning | Open Biology
Several biological processes, including transcriptional regulation by transcription factors (TFs), are dose-dependent. At the mathematical level, dose-dependent processes can be modelled by fitting dose–response curves, for istance, employing Hill-type ...
doi.org
August 6, 2025 at 1:00 PM
I wrote an "Open Questions" piece last year, trying to sum up things I have been thinking about on gene tuning and TFs dosage. In my view, much we don't know is cause we are lacking the tools - but maybe I'm biased as I was a tech developer. THX to the reviewer! :) doi.org/10.1098/rsob...
Reposted by Ander Movilla
🚨 New paper alert 🚨
I am excited to share our new work on epigenetic enhancer priming in early mammalian development
genomebiology.biomedcentral.com/articles/10....
Fantastic collaboration with Wolf Reik’s team, with key contributions from many others, led by the excellent Chris Todd.
Short 🧵
I am excited to share our new work on epigenetic enhancer priming in early mammalian development
genomebiology.biomedcentral.com/articles/10....
Fantastic collaboration with Wolf Reik’s team, with key contributions from many others, led by the excellent Chris Todd.
Short 🧵
Epigenetic priming of mammalian embryonic enhancer elements coordinates developmental gene networks - Genome Biology
Background Embryonic development requires the accurate spatiotemporal execution of cell lineage-specific gene expression programs, which are controlled by transcriptional enhancers. Developmental enha...
genomebiology.biomedcentral.com
July 22, 2025 at 10:26 PM
🚨 New paper alert 🚨
I am excited to share our new work on epigenetic enhancer priming in early mammalian development
genomebiology.biomedcentral.com/articles/10....
Fantastic collaboration with Wolf Reik’s team, with key contributions from many others, led by the excellent Chris Todd.
Short 🧵
I am excited to share our new work on epigenetic enhancer priming in early mammalian development
genomebiology.biomedcentral.com/articles/10....
Fantastic collaboration with Wolf Reik’s team, with key contributions from many others, led by the excellent Chris Todd.
Short 🧵
Reposted by Ander Movilla
🇪🇺🤝 🇰🇷
Today, the Republic of Korea joins Horizon Europe. It is the first Asian country to take part.
Korean entities can now join and lead research consortia with some of the world’s best research organisations to tackle global challenges together.
More info ↓
europa.eu/!QFHCnC
Today, the Republic of Korea joins Horizon Europe. It is the first Asian country to take part.
Korean entities can now join and lead research consortia with some of the world’s best research organisations to tackle global challenges together.
More info ↓
europa.eu/!QFHCnC
July 17, 2025 at 1:22 PM
🇪🇺🤝 🇰🇷
Today, the Republic of Korea joins Horizon Europe. It is the first Asian country to take part.
Korean entities can now join and lead research consortia with some of the world’s best research organisations to tackle global challenges together.
More info ↓
europa.eu/!QFHCnC
Today, the Republic of Korea joins Horizon Europe. It is the first Asian country to take part.
Korean entities can now join and lead research consortia with some of the world’s best research organisations to tackle global challenges together.
More info ↓
europa.eu/!QFHCnC
Reposted by Ander Movilla
Save the Date!
Development has teamed up with the Wellcome-funded consortium the Human Developmental Biology Initiative to co-organise a meeting on #HumanDevelopment.
📅7 - 9 Sep 2026
📍University of Warwick, UK
Register your interest for #HumanDev26: www.biologists.com/meetings/dev...
Development has teamed up with the Wellcome-funded consortium the Human Developmental Biology Initiative to co-organise a meeting on #HumanDevelopment.
📅7 - 9 Sep 2026
📍University of Warwick, UK
Register your interest for #HumanDev26: www.biologists.com/meetings/dev...
July 11, 2025 at 7:46 AM
Save the Date!
Development has teamed up with the Wellcome-funded consortium the Human Developmental Biology Initiative to co-organise a meeting on #HumanDevelopment.
📅7 - 9 Sep 2026
📍University of Warwick, UK
Register your interest for #HumanDev26: www.biologists.com/meetings/dev...
Development has teamed up with the Wellcome-funded consortium the Human Developmental Biology Initiative to co-organise a meeting on #HumanDevelopment.
📅7 - 9 Sep 2026
📍University of Warwick, UK
Register your interest for #HumanDev26: www.biologists.com/meetings/dev...